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Preparation of Porous Mullite-Corundum Ceramics Via Organic Foam Impregnation
Xianzhi Zhou,Shaofeng Zhu,Yuxi Wang,TONG ZHANG 한국재료학회 2022 한국재료학회지 Vol.32 No.2
Porous mullite-corundum ceramics were prepared using organic foam impregnation method with alumina and silica as raw materials. The influence of alkaline treatment and surfactant modification on polyurethane foam were studied. Effects of sintering process and material composition on porous mullite-corundum ceramics were investigated. The results show that the hang-pulp quantity of polyurethane foam increases with alkaline treatment. After treatment with 3 wt% SDS solution, the hang-pulp quantity of polyurethane foam further improved. Open porosity of sample decreased with elevation of sintering temperature and holding time, and compressive strength of sample showed a trend opposite to the change of porosity. The open porosity of the sample was enhanced by the increase of m(Al2O3/SiO2); the compressive strength decreased with increase of m(Al2O3/SiO2). However, when m(Al2O3/SiO2) was 2.5, the compressive strength of the sample reached 6.23 MPa, and the open porosity of the sample was 80.7 %.
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Xiaoyu Li,Xianzhi Zhao,Wen Song,Zibin Tian,Lin Yang,Qinghui Niu,Qi Zhang,Man Xie,Bin Zhou,Yonghong Xu,Jun Wu,Cuiping Zhang 연세대학교의과대학 2018 Yonsei medical journal Vol.59 No.1
Purpose: This study was aimed to investigate the effect of pseudolaric acid B (PAB) on proliferation, invasion and epithelial-to-mesenchymal transition (EMT) in pancreatic cancer cells and to explore the possible mechanism. Materials and Methods: The pancreatic cancer cell line SW1990 was cultured and treated with PAB dose- and time-dependent manners. Cell proliferation and invasion ability were measured by MTT assay and Matrigel/Transwell test, respectively. Semi-quantitative real-time polymerase chain reaction and Western blotting were conducted to detect the expression of EMT markers and the key molecules. Finally, nude mice subcutaneous transplantation tumor model was used to confirm the therapy efficacy of PAB. Results: PAB could inhibit SW1990 cell proliferation and invasion in time- and dose-dependent manners. Vimentin, fibronectin, N-cadherin, Snail, Slug, YAP, TEAD1, and Survivin were down-regulated (p<0.01), while E-cadherin, caspase-9, MST1, and pYAP were up-regulated (p<0.05). Combined PAB and gemcitabine treatment markedly restricted the tumor growth compared with gencitabin or PAB alone groups. Conclusion: PAB could inhibit the proliferation and invasion ability of pancreatic cancer cells through activating Hippo-YAP pathway and inhibiting the process of EMT.
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Jiangtao Fan,Jingyan Wang,Xianzhi Liu,Changping Zhao,Chaobing Zhou,Tasheen Saba,Jiaojiao Wu,Wenkai Hui,Wei Gong 한국원예학회 2022 원예과학기술지 Vol.40 No.3
Zanthoxylum armatum, known as green prickly ash, is a major condiment species planted on a large scale in southwest China. However, its limited cold tolerance has been a significant disadvantage for its cultivation in low-temperature regions. To better understand the antioxidant enzyme activities related to cold resistance, superoxide dismutase (SOD), peroxidase (POD), and catalase (CAT) activities as well as malondialdehyde (MDA) content were investigated under 16 fertilizer and soil moisture treatments to explore the cold resistance response mechanism in Z. armatum. The results showed that low temperatures could significantly affect antioxidant enzyme activities in the leaves of Z. armatum seedlings. The antioxidant enzyme activities of seedlings treated with soil moisture and fertilizer treatments were significantly higher than those without fertilizer. Furthermore, the comprehensive evaluation index (CEI) was positively correlated with SOD, POD, and CAT activities but negatively correlated with MDA content. Meanwhile, the treatment T12 (60% field water capacity + 300 kg·ha-1 nitrogen + 30 kg·ha-1 phosphoric anhydride) had the highest CEI value, whereas T1 (20% water capacity) had the lowest. Based on the regression equation for CEI improvement, the predicted optimal levels for field water capacity (FWC), nitrogen, phosphorus, and potassium were 59.6%–63.4% FWC (average 61.5%), 114.2–248.8 kg N/ha (average 181.5 kg N/ha), 40.1–108.5 kg P2O5/ha (average 74.3 kg P2O5/ha), and 200.2–254.4 kg K2O/ha (average 227.3 kg K2O/ha), respectively. The present study provides the optimal soil moisture and fertilizer concentration required to enhance protective enzyme activity and low-temperature tolerance, which is crucial for improving cold resistance in Z. armatum.
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