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      • KCI등재

        A novel inverse opal zirconia pigment with controllable color saturation

        Li-li Wang,Xin-xin Liu,Xiao-peng Li,Xiu-feng Wang,Li-na Feng,Xu-ri Hou 한양대학교 세라믹연구소 2021 Journal of Ceramic Processing Research Vol.22 No.2

        The inverse opal zirconia pigments were prepared by template method using polystyrene microspheres with the size of 340 ± 10nm as raw material and the in situ carbon was formed to achieve controllable and adjustable color saturation by sintering atvarious temperatures in nitrogen atmosphere with various nitrogen flow rates. The effects of nitrogen atmosphere, nitrogenflow rate and sintering temperature on the morphology, phase and color saturation of the inverse opal zirconia wereinvestigated. The results showed that when the inverse opal zirconia was sintered at 450 oC to 600 oC in nitrogen atmosphere,the green color saturation could be adjusted by changing the nitrogen flow rate from 0.2 L/min to 0.8 L/min. When thenitrogen rate was 0.8L/min, the green color saturation of the inverse opal zirconia could be adjusted by changing the sinteringtemperature from 450 oC to 600 oC. It indicated that the more the amount of in-situ carbon was generated, the more stray lightwas absorbed and the higher green color saturation of the inverse opal zirconia could be obtained. Further increasing thesintering temperature to 700 oC would destroy the inverse opal morphology of zirconia and affect the carbonization of theorganic component.

      • Web Spam Detection Based On Link Diversity and Content Features

        Xu Gongwen,Li Xiaomei,Zhang Zhijun,Xu LiNa 보안공학연구지원센터 2016 International Journal of Security and Its Applicat Vol.10 No.7

        In order to get a higher ranking, spam pages deceive the search engine using cheating technology, which will disturb the users to find useful information via search engine. The web spam is designed for search engines rather than for users, so it is important to make a distinction between the normal web pages and the web spam pages. The links of the normal web pages have a wide variety of sources and the content feature of the normal web pages are distributed regularly, while links source of the web spam pages is single and the content features of them are distributed disorderly. So after analyzing the link diversity and content features distribution of the web pages, a new web page ranking algorithm was proposed in this paper. In this method, the web pages ranking score is calculated by the TrustRank method combining web pages links diversity and the web pages content features. It can be shown from the experimental results that this method can effectively reduce spam pages ranking score.

      • KCI등재

        Nanocomposites of Fe2O3@rGO for adsorptive removal of arsanilic acid from aqueous solution

        Li-Li Sui,Li-Na Peng,Hong-Bo Xu 한국화학공학회 2021 Korean Journal of Chemical Engineering Vol.38 No.3

        Arsanilic acid (ASA), an organic-arsenic veterinary drug used widely, has greatly attracted attention due to its potential threats. We report the nanocomposites of the α-Fe2O3 nanoparticles growth on reduced graphene oxide (rGO) by a one-pot method. The α-Fe2O3 nanoparticles are densely covered on the surface of rGO according to the observations of transmission and scanning electron microscope. The adsorptive capacity (357.4±11.2 mg g1 ) of the Fe2O3@rGO nanocomposites for ASA, which was more than the sum of adsorptive capacities of the pure α-Fe2O3 nanoparticles and rGO, revealed a remarkable enhancement due to the synergetic effect of multiple interactions and the good dispersion of α-Fe2O3 nanoparticles with more active binding sites in the Fe2O3@rGO nanocomposites. The adsorption equilibrium of ASA onto the Fe2O3@rGO nanocomposites was achieved for 60 min, and the adsorption of ASA was dependent of pH and temperature, and independent of the concentration of humic acid ranging from 0 to 20 mg L-1 . After five cycles of adsorption-desorption, the adsorptive amounts of ASA by the regenerative sorbent still retained 85% of adsorptive amount by the fresh sorbents. The adsorption process of ASA can be described by the Langmuir and the pseudo-second-order equations and is exothermic and spontaneous according to thermodynamic analysis.

      • Clinical Study of Tumor Angiogenesis and Perfusion Imaging Using Multi-slice Spiral Computed Tomography for Breast Cancer

        Xu, Na,Lei, Zhen,Li, Xiao-Long,Zhang, Jun,Li, Chen,Feng, Guo-Quan,Li, Di-Nuo,Liu, Jing-Yi,Wei, Qiang,Bian, Ting-Ting,Zou, Tian-Yu Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.1

        Objectives: To explore the correlation between multi-slice spiral CT (MSCT) perfusion parameters and the expression of vascular endothelial growth factor (VEGF) as well as matrix metalloproteinase-2 (MMP-2) in breast cancer. Methods: Forty five breast cancer patients and 16 patients with benign breast tumor, both confirmed by pathology examination, were enrolled. All underwent MSCT perfusion imaging to obtain perfusion maps and data for parameters including blood flow (BF), blood volume (BV) and permeability surface (PS). Cancer patients did not receive treatment prior to surgery. The expression of VEGF and MMP-2 were examined with both immunohistochemistry and Western blotting. Results: The levels of VEGF and MMP-2 by immunohistochemistry were significantly higher in the breast cancer group (P < 0.01) than the benign tumor group. Relative OD values from Western blotting were also higher in cancer cases (P < 0.05). Similarly, the mean MSCT perfusion parameters (BF, BV, PS) were significantly higher in the breast cancer group (P < 0.01), BF and BV positively correlating with VEGF expression (r = 0.878 and 0.809 respectively, P < 0.01); PS and VEGF and MMP-2 expression were also positively correlated (r= 0.860, 0.786 respectively, P < 0.01). Conclusion: There is a correlation between breast cancer MSCT perfusion parameters and VEGF andMMP-2 expression, which might be useful for detection of breast lesions, qualitative diagnosis of breast cancer, and evaluation of breast cancer treatment.

      • KCI등재

        An Integrated Artificial Neural Network-based Precipitation Revision Model

        ( Tao Li ),( Wenduo Xu ),( Li Na Wang ),( Ningpeng Li ),( Yongjun Ren ),( Jinyue Xia ) 한국인터넷정보학회 2021 KSII Transactions on Internet and Information Syst Vol.15 No.5

        Precipitation prediction during flood season has been a key task of climate prediction for a long time. This type of prediction is linked with the national economy and people's livelihood, and is also one of the difficult problems in climatology. At present, there are some precipitation forecast models for the flood season, but there are also some deviations from these models, which makes it difficult to forecast accurately. In this paper, based on the measured precipitation data from the flood season from 1993 to 2019 and the precipitation return data of CWRF, ANN cycle modeling and a weighted integration method is used to correct the CWRF used in today’s operational systems. The MAE and TCC of the precipitation forecast in the flood season are used to check the prediction performance of the proposed algorithm model. The results demonstrate a good correction effect for the proposed algorithm. In particular, the MAE error of the new algorithm is reduced by about 50%, while the time correlation TCC is improved by about 40%. Therefore, both the generalization of the correction results and the prediction performance are improved.

      • KCI등재

        Microstructures and nano mechanical properties of the metal tungsten film

        Zhu Li-na,Li Guo-lu,Wang Hai-dou,Xu Bin-shi,Zhuang Da-ming,Liu Jia-jun 한국물리학회 2009 Current Applied Physics Vol.9 No.3

        The W film was prepared on 1045 steel by magnetron sputtering, with the thickness of 2 ㎛, its surface and cross-section morphologies were investigated with SEM, and the phase structure was analyzed with XRD. X-ray stress determinator was utilized to measure its residual stress, and the nano-hardness and elastic modulus of the film were surveyed by nano-indentation tester. The results show that the surface of W film is very compact and smooth; the particles arranged regularly, the granularity of the thin film is about 1 ㎛. The microcracks, cavities and desquamation were not found in the film and interface, and the bonding between the W film and substrate is well. The XRD results showed that the W film had a body-centered cubic structure, the lattice constant: ɑ = 0.316 nm, the growth preferred orientations are (110) and (220). The compressive stress (-169 MPa) was found on the surface. The average nano-hardness and elastic modulus of W film are 15.22 GPa, 176.64 GPa, respectively, and the mechanical properties of W film are well. The W film was prepared on 1045 steel by magnetron sputtering, with the thickness of 2 ㎛, its surface and cross-section morphologies were investigated with SEM, and the phase structure was analyzed with XRD. X-ray stress determinator was utilized to measure its residual stress, and the nano-hardness and elastic modulus of the film were surveyed by nano-indentation tester. The results show that the surface of W film is very compact and smooth; the particles arranged regularly, the granularity of the thin film is about 1 ㎛. The microcracks, cavities and desquamation were not found in the film and interface, and the bonding between the W film and substrate is well. The XRD results showed that the W film had a body-centered cubic structure, the lattice constant: ɑ = 0.316 nm, the growth preferred orientations are (110) and (220). The compressive stress (-169 MPa) was found on the surface. The average nano-hardness and elastic modulus of W film are 15.22 GPa, 176.64 GPa, respectively, and the mechanical properties of W film are well.

      • KCI등재

        Gut Microbiota Alteration Influences Colorectal Cancer Metastasis to the Liver by Remodeling the Liver Immune Microenvironment

        Yuan Na,Li Xiaoyan,Wang Meng,Zhang Zhilin,Qiao Lu,Gao Yamei,Xu Xinjian,Zhi Jie,Li Yang,Li Zhongxin,Jia Yitao 거트앤리버 소화기연관학회협의회 2022 Gut and Liver Vol.16 No.4

        Background/Aims:This study aimed to explore the effect of gut microbiota-regulated Kupffer cells (KCs) on colorectal cancer (CRC) liver metastasis. Methods: A series of in vivo and in vitro researches were showed to demonstrate the gut microbiota and its possible mechanism in CRC liver metastasis. Results: Fewer liver metastases were identified in the ampicillin-streptomycin-colistin and colistin groups. Increased proportions of Parabacteroides goldsteinii, Bacteroides vulgatus, Bacteroides thetaiotaomicron, and Bacteroides uniformis were observed in the colistin group. The significant expansion of KCs was identified in the ampicillin-streptomycin-colistin and colistin groups. B. vulgatus levels were positively correlated with KC levels. More liver metastases were observed in the vancomycin group. An increased abundance of Parabacteroides distasonis and Proteus mirabilis and an obvious reduction of KCs were noted in the vancomycin group. P. mirabilis levels were negatively related to KC levels. The number of liver metastatic nodules was increased in the P. mirabilis group and decreased in the B. vulgatus group. The number of KCs decreased in the P. mirabilis group and increased in the B. vulgatus group. In vitro, as P. mirabilis or B. vulgatus doses increased, there was an opposite effect on KC proliferation in dose- and time-dependent manners. P. mirabilis induced CT26 cell migration by controlling KC proliferation, whereas B. vulgatus prevented this migration. Conclusions: An increased abundance of P. mirabilis and decreased amount of B. vulgatus play key roles in CRC liver metastasis, which might be related to KC reductions in the liver.

      • KCI등재

        Identification, fine mapping and characterization of Rht-dp, a recessive wheat dwarfing (reduced height) gene derived from Triticum polonicum

        Hou-Yang Kang,Li-Juan Lin,Zhi-Jian Song,Jing-Ya Yuan,Mei-Yu Zhong,Hai-Qin Zhang,Xing Fan,Li-Na Sha,Yi Wang,Li-Li Xu,Jian Zeng,Yong-Hong Zhou 한국유전학회 2012 Genes & Genomics Vol.34 No.5

        Semi-dwarfism is an agronomically important trait in breeding for resistance to damage by wind and rain (lodging resistance)and for stable high yields. Dwarf Polish wheat (Triticum polonicum L., 2n = 4x = 28, AABB AS304) is a potential donor of dwarfing and other traits for common wheat improvement. A genetic analysis using an F2 population derived from a cross of AS304 and tall cultivar AS302 and derived F2:3 lines indicated that AS304 carries a recessive dwarfing gene, temporarily designated Rht-dp. Molecular markers and bulked segregant analysis were used to characterize and map the gene. Eight polymorphic SSR markers (Xwmc511, Xgwm495, Xgwm 113, Xgwm192, Xgpw7026, Xgpw3017, Xgpw1108 and Xgpw7521) on chromosome arm 4BS and two AFLP markers (M8/E5 and M4/E3) were mapped relative to the dwarfing locus. The closest linked markers, Xgpw3017 and M8/E5 at 0.5 and 3.5 cM, respectively, from Rht-dp will enable its marker assisted transfer to wheat breeding populations. Allelic tests indicated that Rht-dp was allelic to Rht-B1b; hence it may be an alternative allele at the Rht-B1 locus.

      • Knockdown of HMGN5 Expression by RNA Interference Induces Cell Cycle Arrest in Human Lung Cancer Cells

        Chen, Peng,Wang, Xiu-Li,Ma, Zhong-Sen,Xu, Zhong,Jia, Bo,Ren, Jin,Hu, Yu-Xin,Zhang, Qing-Hua,Ma, Tian-Gang,Yan, Bing-Di,Yan, Qing-Zhu,Li, Yan-Lei,Li, Zhen,Yu, Jin-Yan,Gao, Rong,Fan, Na,Li, Bo,Yang, Jun Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.7

        HMGN5 is a typical member of the HMGN (high mobility group nucleosome-binding protein) family which may function as a nucleosomal binding and transcriptional activating protein. Overexpression of HMGN5 has been observed in several human tumors but its role in tumorigenesis has not been fully clarified. To investigate its significance for human lung cancer progression, we successfully constructed a shRNA expression lentiviral vector in which sense and antisense sequences targeting the human HMGN5 were linked with a 9-nucleotide loop. Inhibitory effects of siRNA on endogenous HMGN5 gene expression and protein synthesis were demonstrated via real-time RT-PCR and western blotting. We found HMGN5 silencing to significantly inhibit A549 and H1299 cell proliferation assessed by MTT, BrdU incorporation and colony formation assays. Furthermore, flow cytometry analysis showed that specific knockdown of HMGN5 slowed down the cell cycle at the G0/G1 phase and decreased the populations of A549 and H1299 cells at the S and G2/M phases. Taken together, these results suggest that HMGN5 is directly involved in regulation cell proliferation in A549 and H1299 cells by influencing signaling pathways involved in cell cycle progression. Thus, our finding suggests that targeting HMGN5 may be an effective strategy for human lung cancer treatment.

      • KCI등재

        A Three-Stage Dynamic Risk Model for Metro Shield Tunnel Construction

        Na Xu,Chaoran Guo,Li Wang,Xueqing Zhou,Ying Xie 대한토목학회 2024 KSCE Journal of Civil Engineering Vol.28 No.2

        The complex construction process of the metro shield method often leads to safety accidents. The various construction stages of shield tunnel construction comprise different construction activities and are accompanied by different safety risk factors. However, traditional risk assessment often evaluates the risk factors as a whole before shield tunnel construction and does not evaluate the risk factors dynamically by construction stages and by construction activities. To fill this gap, this paper aims to construct a dynamic Bayesian-based safety risk assessment model for shield tunnel construction from the perspective of changing construction stages and activities. First, safety risk factors were identified using the work breakdown structure-risk breakdown structure (WBS-RBS) method. Then, a three-stage dynamic assessment model of safety risks was constructed to depict the shield launch, shield tunnel, and shield reach. The dynamic Bayesian network (DBN) was improved to address the model with triangular fuzzy numbers and the leaky noisy-or-gate extension model. Finally, a case study was conducted. The model proposed in this paper is able to reveal the dynamic evolution of safety risks triggered by different construction activities. It offers a new simulated model for the prevention of safety accidents in the construction of metro shields.

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