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600W급 IPMSM의 구동특성 변화에 따른 온도 내력 분석
이원식(Wonsik_Lee),고덕화(Duk-Hwa Go),김용태(Yong-Tae Kim),조규원(Gyu-Won Cho),김규탁(Gyu Tak Kim) 대한전기학회 2016 대한전기학회 학술대회 논문집 Vol.2016 No.10
본 논문에서는 동일 출력에서 연기전력 증가 및 형상 변경을 통한 효율 향상 전동기와 기본모델 전동기를 열 등가회로망법을 사용한 열해석을 수행하여 온도 내력을 비교, 분석하였다.
Joohyeong Lee,Eunmi Kim,Min-Kyung Kang,Jihye Ryu,Ji Eon Kim,Eun-Ae Shin,Yangie Pinanga,Kyung-hee Pyo,Haesong Lee,Eun Hae Lee,Heejin Cho,Jayeon Cheon,Wonsik Kim,Eek-hoon Jho,Semi Kim,Jung Weon Lee 생화학분자생물학회 2022 BMB Reports Vol.55 No.12
Mutation of the gene for adenomatous polyposis coli (APC), asseen in ApcMin/+ mice, leads to intestinal adenomas and carcinomasvia stabilization of β-catenin. Transmembrane 4 L sixfamily member 5 (TM4SF5) is involved in the development ofnon-alcoholic fatty liver disease, fibrosis, and cancer. However,the functional linkage between TM4SF5 and APC or β-cateninhas not been investigated for pathological outcomes. After interbreedingApcMin/+ with TM4SF5-overexpressing transgenic(TgTM4SF5) mice, we explored pathological outcomes in the intestinesand livers of the offspring. The intestines of 26-week-olddual-transgenic mice (ApcMin/+:TgTM4SF5) had intramucosal adenocarcinomasbeyond the single-crypt adenomas in ApcMin/+ mice. Additional TM4SF5 overexpression increased the stabilizationof β-catenin via reduced glycogen synthase kinase 3β (GSK3β)phosphorylation on Ser9. Additionally, the livers of the dualtransgenicmice showed distinct sinusoidal dilatation and featuresof hepatic portal hypertension associated with fibrosis,more than did the relatively normal livers in ApcMin/+ mice. Interestingly, TM4SF5 overexpression in the liver was positivelylinked to increased GSK3β phosphorylation (opposite to thatseen in the colon), β-catenin level, and extracellular matrix (ECM)protein expression, indicating fibrotic phenotypes. Consistentwith these results, 78-week-old TgTM4SF5 mice similarly had sinusoidaldilatation, immune cell infiltration, and fibrosis. Altogether,systemic overexpression of TM4SF5 aggravates pathologicalabnormalities in both the colon and the liver.
KoFlux: A New Tool to Study the Biosphere-Atmosphere Interactions in Asia
Joon Kim,Wonsik Kim,Byong-lyol Lee,Ki-hyun Kim,Kyu-rang Kim,Min-young Kim,Bang-yong Lee,Do-won Lee,Gang-woong Lee,Jeong-taek Lee,Jong-hwan Lim,Jai-ho Oh,Eun-woo Park,Jae-seol Shim,Jin-il Yun,Chae-shik 한국기상학회 2002 대기 Vol.12 No.1
Light-induced electrical switch <i>via</i> photo-responsive nanocomposite film
Lee, Wonsik,Kim, Dongjun,Lim, Joonyoung,Kim, Geonho,Kim, Ikyon,Kim, Songkuk,Kim, Jiwon Elsevier 2018 Sensors and actuators. B Chemical Vol.266 No.-
<P><B>Abstract</B></P> <P>Photo-responsive nanomaterials have attracted a lot of attention since they allow a remote control with a non-invasive stimulus—light. Owing to this property, it has been applied to next-generation electrical devices, which are desired to be flexible and transparent for a wider range of applications. Herein, we developed a flexible, transparent and conductive film which can change its shape <I>via</I> light of specific wavelength to control the electrical conductivity between electrodes. The film is composed of three layers: azobenzene incorporated poly(dimethylsiloxane), AzoPDMS; silk fibroin; and silver nanowires, AgNWs. When azobenzene within the polymer changes its molecular arrangement upon irradiation, the difference in volume changes of AzoPDMS and silk fibroin layer results in the film to bend. Since a silk fibroin layer folds inward upon irradiation, AgNWs are coated onto the silk fibroin layer to be selectively in contact with the electrodes. This photo-responsive nanocomposite film is flexible, transparent and conductive which can be connected to the circuit on demand <I>via</I> light acting as an electrical switch. We believe it can be combined with various transparent electronic devices to further expand its applications.</P> <P><B>Highlights</B></P> <P> <UL> <LI> A flexible, transparent and conductive photo-bending film was fabricated. </LI> <LI> The photo-responsive film consists of photo-responsive/support/conductive layers. </LI> <LI> The film could bend up to 90° with switching time of a few seconds upon irradiation. </LI> <LI> The conductivity of film can be optimized by changing the concentration of silver nanowires. </LI> <LI> The film can be connected to the circuit on demand acting as a light-induced electrical switch. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
Lee Wonsik 한국미생물학회 2022 The journal of microbiology Vol.60 No.12
Transposon mutant libraries are an important resource to study bacterial metabolism and pathogenesis. The fitness analysis of mutants in the libraries under various growth conditions provides important clues to study the physiology and biogenesis of structural components of a bacterial cell. A transposon library in conjunction with next-generation sequencing techniques, collectively named transposon sequencing (Tnseq), enables high-throughput genome profiling and synthetic lethality analysis. Tn-seq has also been used to identify essential genes and to study the mode of action of antibacterials. To construct a high-density transposon mutant library, an efficient delivery system for transposition in a model bacterium is essential. Here, I describe a detailed protocol for generating a high-density phage-based transposon mutant library in a Staphylococcus aureus strain, and this protocol is readily applicable to other S. aureus strains including USA300 and MW2.
Compressive Deformation Behavior of Nanocrystalline Al Alloys at High Temperatures
Lee, Wonsik,Jang, Jin Man,Ko, Se-Hyun,Lee, Chang-Woo The Japan Institute of Metals 2006 MATERIALS TRANSACTIONS Vol.47 No.6
<P>Three kinds of nanocrystalline materials, pure Al, Al-1.5Mg and Al-0.7Mg-1.0Cu, were compressive deformed at 300°C. In load-displacement curves, sharp drop of load after yielding was observed in Al-1.5Mg and Al-0.7Mg-1.0Cu alloys while slight increase of load in pure Al. The load drop results from effective grain boundary sliding, which indicates that alloying elements, Mg and/or Cu, assist the occurrence of grain boundary sliding. Plateau region where load is constantly sustained appeared following load drop, especially at strain rate of 1×10<SUP>−3</SUP> s<SUP>−1</SUP> in Al-1.5Mg and Al-0.7Mg-1.0Cu alloys. During deformation in plateau region grains were highly refined from 100 nm to about 10 nm and then, the refined grains grew again up to 100 nm by subsequent deformation. All nanocrystalline Al alloys including pure Al showed strain softening phenomenon due to grain boundary sliding at 300°C regardless of strain rate.</P>