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Weiwei Gao,Fei Zhang,Tai Ma,Jiqing Hao 대한위암학회 2020 Journal of gastric cancer Vol.20 No.2
Purpose: This study was to investigate the prognostic significance of the preoperative fibrinogen and systemic inflammation response index (F-SIRI) in a Chinese cohort of resectable gastric cancer. Materials and Methods: Baseline characteristics, preoperative fibrinogen levels and peripheral neutrophil, monocyte, and lymphocyte counts were retrospectively reviewed in 240 patients who underwent radical gastrectomy. The optimal cut-off values for fibrinogen and SIRI were defined as 4.0 g/L and 1.2. Then patients with hyperfibrinogenemia (≥4.0 g/L) and high SIRI (≥1.2) were assigned with an F-SIRI of 2 (both of these hematological abnormalities), 1 (one of these abnormalities), and 0 (neither abnormality), respectively. The prognostic value was examined by univariate and multivariate survival analysis. Results: Preoperative F-SIRI was significantly correlated with tumor size, fibrinogen level, and adjuvant chemotherapy. Whereas there was no significant difference in age, gender, tumor location or other characteristics between groups. In addition, high preoperative F-SIRI was significantly associated with worse disease-free survival (DFS) (hazard ratio [HR], 2.299; 95% confidence interval [CI], 1.482–3.566; P<0.001) and overall survival (OS) (HR, 2.461; 95% CI, 1.584–3.824; P<0.001) by univariate survival analysis. Moreover, it remained an independent predictor for impaired DFS (HR, 2.023; 95% CI, 1.273–3.215; P=0.003) and OS (HR, 2.341; 95% CI, 1.480–3.705; P<0.001) in multivariate Cox regression analysis. Conclusions: Preoperative F-SIRI could serve as a significantly prognostic marker for long-term survival in Chinese patients who underwent radical gastrectomy.
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Facile Synthesis of CdTe Nanorods from the Growth of Te Nanorods
Weiwei Xu,Jinzhong Niu,Guimin Tian,Xinghui Wu,Yongguang Cheng,Xiaoyang Hu,Haoshan Hao 대한화학회 2017 대한화학회지 Vol.61 No.4
One-dimensional CdTe nanorods (NRs) are obtained by the reaction of various Cd precursors with single crystalline Te nanorod templates, which are pre-synthesized from Te precursors by a simple and reproducible solvothermal method. Throughout the process, the diffraction intensity of different crystal facets of single crystalline Te NRs varied with reaction times. Finally, by alloying Cd ions along the axial direction of Te NRs, polycrystalline cubic phase CdTe NRs with diameters of 80–150 nm and length up to 1.2–2.4 μm are obtained. The nucleation and growth processes of Te and CdTe NRs are discussed in details, and their properties are characterized by XRD, SEM, TEM, Raman scattering, and UV-vis absorption spectra. It was found that the key elements of synthesizing CdTe NRs such as reaction temperatures and Cd sources will strongly influence the final shape of CdTe NRs.
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Facile Synthesis of CdTe Nanorods from the Growth of Te Nanorods
Xu, Weiwei,Niu, Jinzhong,Zheng, Shuang,Tian, Guimin,Wu, Xinghui,Cheng, Yongguang,Hu, Xiaoyang,Liu, Shuaishuai,Hao, Haoshan Korean Chemical Society 2017 대한화학회지 Vol.61 No.4
One-dimensional CdTe nanorods (NRs) are obtained by the reaction of various Cd precursors with single crystalline Te nanorod templates, which are pre-synthesized from Te precursors by a simple and reproducible solvothermal method. Throughout the process, the diffraction intensity of different crystal facets of single crystalline Te NRs varied with reaction times. Finally, by alloying Cd ions along the axial direction of Te NRs, polycrystalline cubic phase CdTe NRs with diameters of 80-150 nm and length up to $1.2-2.4{\mu}m$ are obtained. The nucleation and growth processes of Te and CdTe NRs are discussed in details, and their properties are characterized by XRD, SEM, TEM, Raman scattering, and UV-vis absorption spectra. It was found that the key elements of synthesizing CdTe NRs such as reaction temperatures and Cd sources will strongly influence the final shape of CdTe NRs.
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Gao, Weiwei,Zhang, Fei,Ma, Tai,Hao, Jiqing The Korean Gastric Cancer Association 2020 Journal of gastric cancer Vol.20 No.2
Purpose: This study was to investigate the prognostic significance of the preoperative fibrinogen and systemic inflammation response index (F-SIRI) in a Chinese cohort of resectable gastric cancer. Materials and Methods: Baseline characteristics, preoperative fibrinogen levels and peripheral neutrophil, monocyte, and lymphocyte counts were retrospectively reviewed in 240 patients who underwent radical gastrectomy. The optimal cut-off values for fibrinogen and SIRI were defined as 4.0 g/L and 1.2. Then patients with hyperfibrinogenemia (≥4.0 g/L) and high SIRI (≥1.2) were assigned with an F-SIRI of 2 (both of these hematological abnormalities), 1 (one of these abnormalities), and 0 (neither abnormality), respectively. The prognostic value was examined by univariate and multivariate survival analysis. Results: Preoperative F-SIRI was significantly correlated with tumor size, fibrinogen level, and adjuvant chemotherapy. Whereas there was no significant difference in age, gender, tumor location or other characteristics between groups. In addition, high preoperative F-SIRI was significantly associated with worse disease-free survival (DFS) (hazard ratio [HR], 2.299; 95% confidence interval [CI], 1.482-3.566; P<0.001) and overall survival (OS) (HR, 2.461; 95% CI, 1.584-3.824; P<0.001) by univariate survival analysis. Moreover, it remained an independent predictor for impaired DFS (HR, 2.023; 95% CI, 1.273-3.215; P=0.003) and OS (HR, 2.341; 95% CI, 1.480-3.705; P<0.001) in multivariate Cox regression analysis. Conclusions: Preoperative F-SIRI could serve as a significantly prognostic marker for long-term survival in Chinese patients who underwent radical gastrectomy.
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Wenzhong Wang,Weiwei Zhang,Shan Meng,Lujie Jia,Miao Tan,Chenchun Hao,Yujie Liang,JUN WANG,Bin Zou 대한금속·재료학회 2016 ELECTRONIC MATERIALS LETTERS Vol.12 No.6
Reducing the fast recombination of photogenerated electron-hole pairsof semiconductor photocatalyst is very important to improve itsphotocatalysis. In this paper we fabricate Cu2O nanocube-decoratedBiVO4 nanocrystal (denoted as BiVO4@Cu2O nanocrystal@nanocube)heterostructure photocatalyst by coupling n-type BiVO4 with p-type Cu2O. The BiVO4@Cu2O nanocrystal@nanocube photocatalysts show superiorphotocatalytic activities in photoelectrochemical (PEC) activity andphotocatalytic water oxidation to BiVO4 photocatalysts under visible lightillumination. The BiVO4@Cu2O nanocrystal@nanocube heterostructureelectrode achieves the highest photocurrent density of ~ 10 μA cm−2 at 0 Vversus Ag/AgCl, 5 times higher than that of BiVO4 nanocrystal electrode (~ 2 μA cm−2). The light induced evolution rate of O2generation for BiVO4@Cu2O nanocrystal@nanocube heterostructures is as high as 150 μmol h−1100 mg cat−1, more than 3times higher than that (48 μmol h−1100 mg cat−1) of BiVO4 nanocrystals. The enhanced photocatalysis activities of theBiVO4@Cu2O nanocrystal@nanocube photocatalysts are attributed to the efficient separation of the photoexcited electron-holepairs caused by inner electronic field (IEF) of p-n junction. This study opens up new opportunities in designing photoactivematerials with highly enhanced performance for solar energy conversion.
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Chengbin Wang,Hao Chen,Xiaopeng Wang,Zhongping Wu,Weiwei Liu,Yuanmei Guo,Jun Ren,Nengshui Ding 아세아·태평양축산학회 2019 Animal Bioscience Vol.32 No.12
Objective: Copy number variations (CNVs) are a major source of genetic diversity complementary to single nucleotide polymorphism (SNP) in animals. The aim of the study was to perform a comprehensive genomic analysis of CNVs based on high density whole-genome SNP markers in Chinese Dongxiang spotted pigs. Methods: We used customized Affymetrix Axiom Pig1.4M array plates containing 1.4 million SNPs and the PennCNV algorithm to identify porcine CNVs on autosomes in Chinese Dongxiang spotted pigs. Then, the next generation sequence data was used to confirm the detected CNVs. Next, functional analysis was performed for gene contents in copy number variation regions (CNVRs). In addition, we compared the identified CNVRs with those reported ones and quantitative trait loci (QTL) in the pig QTL database. Results: We identified 871 putative CNVs belonging to 2,221 CNVRs on 17 autosomes. We further discarded CNVRs that were detected only in one individual, leaving us 166 CNVRs in total. The 166 CNVRs ranged from 2.89 kb to 617.53 kb with a mean value of 93.65 kb and a genome coverage of 15.55 Mb, corresponding to 0.58% of the pig genome. A total of 119 (71.69%) of the identified CNVRs were confirmed by next generation sequence data. Moreover, functional annotation showed that these CNVRs are involved in a variety of molecular functions. More than half (56.63%) of the CNVRs (n = 94) have been reported in previous studies, while 72 CNVRs are reported for the first time. In addition, 162 (97.59%) CNVRs were found to overlap with 2,765 previously reported QTLs affecting 378 phenotypic traits. Conclusion: The findings improve the catalog of pig CNVs and provide insights and novel molecular markers for further genetic analyses of Chinese indigenous pigs.
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AN IMPROVED METHOD FOR TRANSFERRING GRAPHENE GROWN BY CHEMICAL VAPOR DEPOSITION
YUJIE REN,CHAOFU ZHU,WEIWEI CAI,HUIFENG LI,YUFENG HAO,YAPING WU,SHANSHAN CHEN,QINGZHI WU,RICHARD D. PINER,RODNEY S. RUOFF 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2012 NANO Vol.7 No.1
In this paper, we report an improved transfer of graphene by directly picking up the graphene with target substrates and the comparison of such transferred graphene samples with other graphene samples transferred by the commonly used "PMMA-based transfer" method. Raman spectroscopy studies show that this "direct transfer method" does not degrade the graphene structure and field effect transistor measurements show that it does not introduce any extra doping in graphene; in contrast, PMMA-based transfer samples have strong n-type doping. We also find that graphene samples achieved by this direct transfer method show higher mobility than graphene obtained from the PMMA-based transfer method.
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Wenkai Zhang,Yanshan Zhan,Xiuxiu Gao,Runming Li,Weiwei Zhu,Hao Xu,Baoying Liu,Xiaomin Fang,Yuanqing Xu,Tao Ding 한국고분자학회 2018 Macromolecular Research Vol.26 No.1
Herein, we report the effect of oxygen functionalities of graphene oxide on thermal activated polymerization and thermal properties of reactive benzoxazine nanocomposites. The numbers of oxygen moieties of graphene oxide (GO) are controlled by hydrothermal reduction. The polymerization behavior of benzoxazine monomer (BA-a) is studied by Fourier transform infrared spectroscopy, differential scanning calorimetry and rheological analysis. It is hypothesized that the GO not only exhibits accelerated effect on the polymerization of the BA-a, but also the oxygen moieties such as carboxyl groups of GO interact with the benzoxazine polymers, leading to several orders of magnitude increase in the chemoviscosity and modulus of composite system. Thermal conductivity of poly(BA-a)/GO composite increases from an initial value of ∼0.27 W/mK to 0.47 W/mK as the loading increases from 1 wt% to 6 wt% (enhancement factor up to 176%). Moreover, the nanocomposites display enhanced initial decomposition temperature and char yields as the degree of GO reduction increases.
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