http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Yuan, Yuan,Cai, Hui,Yang, Xiao-Jun,Li, Wei,He, Jin,Guo, Tian-Kang,Chen, Yi-Rong Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.14
Background: The aim of this study was to investigate the effect of a c-myc antisense oligodeoxynucleotide and 5-fluorouracil on the expression of c-myc, invasion and proliferation of HEPG-2 liver cancer cells. Materials and Methods: HEPG-2 cells were treated with lipiosome-mediated c-myc ADSON and 5-fluorouracil. The proliferation inhibition rate and invasion were measured by MTT and invasion assay, respectively. Cell apoptosis was detected by flow cytometry and expression of c-myc by RT-PCR and immunohistochemistry. Results: The proliferation inhibition rate was significantly higher in the antisense oligodeoxynucleotide added-5-fluorouracil group than single antisense oligodeoxynucleotide or 5-fluorouracil group (p<0.05). G0/G1 cells in the antisense oligodeoxynucleotide group and S cells in the 5-fluorouracil groups were significantly increased than that in the control group, respectively (P<0.01). The amplification strips of PCR products in 5-FU, ASODN and combination groups were significantly weaker than that in the control group (P<0.01). The percentage of c-myc-protein-positive cells were significantly lower in antisense oligodeoxynucleotide, 5-fluorouracil and combination groups than that in the control group (P<0.01). Conclusions: A liposome-mediated c-myc antisense oligodeoxynucleotide and 5-fluorouracil can inhibit the proliferation and invasion of liver cancer cells by reducing the expression of c-myc. A c-myc antisense oligodeoxynucleotide can increase the sensitivity of liver cancer cells to 5-fluorouracil and decrease the dosage of the agent necessary for efficacy, providing an experimental basis for the clinical therapy of liver cancer.
Wei Zhou,Zhi-yuan Wei,Guang-fei Wang,Kang-ning Han,Ran Liu,Lian-Hua Ma 한국섬유공학회 2021 Fibers and polymers Vol.22 No.4
Accurate characterisation of transverse tensile deformation and damage evolution is of importance for evaluatingthe failure behaviors of three-dimensional (3D) braided composites. In the present study, a finite element method (FEM) andseveral non-destructive testing methods including acoustic emission, digital image correlation, and infrared thermography aredeveloped to investigate the transverse tensile deformation and damage evolution of 3D five-directional braided composites. In the finite element approach, a matrix-impregnated fiber bundles (MIFB) model and a representative volume cell (RVC)model, which take into account the fiber bundles and matrix, are respectively established to predict the effective mechanicalproperties of fiber bundles and simulate the deformation and progressive damage of such composites. The damaged locationsand the failure modes including matrix crack, fiber debonding and shear fracture of fiber are predicted and verified byexperimental tests. The non-destructive tests show that the transverse tensile fracture process can be divided into four stageswhich correspond to acoustic emission signals severally. The combination of the FEM based numerical modeling andmultiple non-destructive characterisation methods can accurately monitor the deformation and damage behaviors of 3Dbraided composites under transverse tensile loads and thus provide a reference for structural health monitoring of compositesin practical application.
Wei Yuan,Qing-feng Wang,Wen-han Pei,Si-yu Li,Tian-min Wang,Hui-peng Song,Dan Teng,Ting-guo Kang,Hui Zhang 고려인삼학회 2024 Journal of Ginseng Research Vol.48 No.1
Background: Ginseng (Panax ginseng Mayer) is an important natural medicine. However, a long culture period andchallenging quality control requirements limit its further use. Although artificial cultivation can yield a sustainablemedicinal supply, research on the association between the transplantation and chaining of metabolicnetworks, especially the regulation of ginsenoside biosynthetic pathways, is limited. Methods: Herein, we performed Liquid chromatography tandem mass spectrometry based metabolomic measurementsto evaluate ginsenoside accumulation and categorise differentially abundant metabolites (DAMs). Transcriptome measurements using an Illumina Platform were then conducted to probe the landscape of geneticalterations in ginseng at various ages in transplantation mode. Using pathway data and crosstalk DAMs obtainedby MapMan, we constructed a metabolic profile of transplantation Ginseng. Results: Accumulation of active ingredients was not obvious during the first 4 years (in the field), but followingtransplantation, the ginsenoside content increased significantly from 6 8 years (in the wild). Glycerolipidmetabolism and Glycerophospholipid metabolism were the most significant metabolic pathways, as Lipids andlipid-like molecule affected the yield of ginsenosides. Starch and sucrose were the most active metabolic pathwaysduring transplantation Ginseng growth. Conclusion: This study expands our understanding of metabolic network features and the accumulation of specificcompounds during different growth stages of this perennial herbaceous plant when growing in transplantationmode. The findings provide a basis for selecting the optimal transplanting time.
Application of Signal Compression into Medical Surgery Robot with Cable-Pulley System
Yuan Long Wei,Yo Hwan Kang,Chi Yen Kim,Min Cheol Lee 제어로봇시스템학회 2010 제어로봇시스템학회 국제학술대회 논문집 Vol.2010 No.10
Robot Technology and Medical Surgery combination has already been implemented into the surgical operation, such as the laparoscopy surgery. For reduce the risk of the Invasive surgery, we use robotic surgery instead of surgeon motion, which can be operated by realizing haptic torque control. But the surgical instrument cannot attach any electric sensors because of the human body obligations. To enhance the haptic force feedback without the sensors, in our system, we use the Pre-tensioned cable beside the instrument torque framework. In this paper, we will generate the feedback impulse signal through linear element using Signal Compression and study the method to estimate the system structure dynamic equation for the whole controller design. We can estimate the unknown parameters from the comparing the Bode diagrams of its impulse response and model’s response.
Lin, Yuan-Pei,Zhang, Zeng-huan,Tang, Wei,Lu, Yong-Cheng,Ding, Jian-Kang,Zhang, Jian-Ying Korean Group of IABSE;Korea wind Engineering Resea 2006 Proceedings of the International Symposium on Sea- Vol.2006 No.-
Dong Hai Bridge in Shanghai is the longest in world and the first sea-crossing project in china, the total length of which is 32.5km and the width of the bridge is 31.5m. In this paper the general concepts of design, construction and durability are introduced. 상하이의 동해대교는 전장 32.5km 폭 31.5m 의 세계 최장 교량이며, 중국에서는 최초의 해상 횡단 프로젝트이다. 이논문에서는 동해대교의 설계, 건설, 그리고 내구성에 대한 기본 개념을 소개한다.
Applying Formal Methods to Modeling and Analysis of Real-time Data Streams
Kapitanova, Krasimira,Wei, Yuan,Kang, Woo-Chul,Son, Sang-H. Korean Institute of Information Scientists and Eng 2011 Journal of Computing Science and Engineering Vol.5 No.1
Achieving situation awareness is especially challenging for real-time data stream applications because they i) operate on continuous unbounded streams of data, and ii) have inherent realtime requirements. In this paper we showed how formal data stream modeling and analysis can be used to better understand stream behavior, evaluate query costs, and improve application performance. We used MEDAL, a formal specification language based on Petri nets, to model the data stream queries and the quality-of-service management mechanisms of RT-STREAM, a prototype system for data stream management. MEDAL's ability to combine query logic and data admission control in one model allows us to design a single comprehensive model of the system. This model can be used to perform a large set of analyses to help improve the application's performance and quality of service.
Applying Formal Methods to Modeling and Analysis of Real-time Data Streams
Krasimira Kapitanova,Yuan Wei,Woochul Kang,Sang H. Son 한국정보과학회 2011 Journal of Computing Science and Engineering Vol.5 No.1
Achieving situation awareness is especially challenging for real-time data stream applications because they i) operate on continuous unbounded streams of data, and ii) have inherent realtime requirements. In this paper we showed how formal data stream modeling and analysis can be used to better understand stream behavior, evaluate query costs, and improve application performance. We used MEDAL, a formal specification language based on Petri nets, to model the data stream queries and the quality-of-service management mechanisms of RT-STREAM, a prototype system for data stream management. MEDAL’s ability to combine query logic and data admission control in one model allows us to design a single comprehensive model of the system. This model can be used to perform a large set of analyses to help improve the application’s performance and quality of service.
Plasmonic Nanoantennae Fabricated by Focused Ion Beam Milling
Jiang-Tao Lv,Yuan Yan,Wei-Kang Zhang,Yun-Hui Liu,Zi-Yu Jiang,Guang-Yuan Si 한국정밀공학회 2015 International Journal of Precision Engineering and Vol. No.
We show a novel approach to fabricate plasmonic nanoantennae based on a maskless focused ion beam nanoring patterning process. Antenna nanoarrays with desired outlines are achieved by precisely controlling the geometric parameters during the milling process. Various nanoantenna designs of bow-tie, nanoclusters (pentamers), and ellipsoid shaped satellites surrounded particle lattices arerealized. The whole fabrication method is programmable and monolithic since only a one-step milling process is involved. The opticalproperties are experimentally characterized. Such nanoantennae may find extensive applications in chemical/bio-sensing due toremarkably enhanced near field intensity at the plasmon resonance.
Reduction of [Fe(III)EDTA]ˉcatalyzed by activated carbon modified with KOH solution
Lin Yang,Xiang-li Long,Xue-wei Chou,Cong Li,Wei-kang Yuan 한국공업화학회 2013 Journal of Industrial and Engineering Chemistry Vol.19 No.3
NO and SO2 can be eliminated simultaneously by [Fe(II)EDTA]2ˉ solution with a pH range of 5.6–8.0 at 25–80 8C. Activated carbon is used to catalyze the regeneration of [Fe(II)EDTA]2ˉ. In this paper, KOH solution has been utilized to modify the carbon to improve its catalytic capability. Experimental results show that the optimal modification factors are as follow: KOH concentration 6.0 mol l-1, impregnation time 9 h, activation temperature 700 8C and activation time 4 h. After KOH modification, the surface area of activated carbon decreases. But its basicity is enhanced, which plays an important role in improving the catalytic characteristics of activated carbon in the reduction of [Fe(III)EDTA]ˉ. The experimental results demonstrate that the activated carbon modified by concentrated KOH solution can get a higher NO removal efficiency than the original activated carbon.