완벽한 룸메이트를 얻기 위한 룸메이트 매칭 플랫폼 서비스 연구 : 2030세대를중심으로

Ui-Jin Lee,Seung-In Kim 한국서비스디자인학회 2019 서비스디자인융합연구 Vol.3 No.1

이 연구는 급증하는 1인 가구의 증가로 기존의 혼자 사는 주거 형태에서 서로의 필요, 조건에 따라 세분화하여 룸메이트를 찾을 수 있는 ‘룸메이트 매칭 플랫폼 서비스’ 제안에 목적이 있다. 이러한 서비스는 부동산 애플리케이션에 적용하면 적합하다고 판단하였고, 국내 부동산 시장의 수요를 더욱 충족시킬 수 있는 서비스라고 여겨진다. 이 연구를 통하여 향후 4차 산업 혁명으로 더 커지는 국내 부동산 애플리케이션 서비스를 중심으로 1인 가구의 초기 사회 진출을 위한 방법을 확대하고, 적합한 주거환경의 활성화에 도움이 되고자 한다. 이 방식은 기존의 스마트 폰에서 함께 지낼 룸메이트를 찾는다는 단순 방향에서, 다양한 조건을 가지고 우선순위를 두어 필터로 걸러내어 찾는 보다 효과적인 룸메이트 찾기 방식이다. 이 연구를 발판으로 국내 부동산 시장 활성화가 더욱 커질 수 있길 기대하며, 급증하는 1인 가구 서비스 발전의 기초자료로 활용되고자 한다. The study is aimed at proposing a roommate matching platform service which can find roommates according to the needs and conditions of each other in the form of existing single living with the surge of single - person households. These services are considered to be suitable for real estate applications and are considered to be a service that can better meet the demand of the domestic real estate market. Through this research, I intend to expand the method for the advancement of one person s household into the early social life centered on the domestic real estate application service, which is getting bigger due to the 4th industrial revolution in the future, and help to activate suitable living environment. This method is a more effective way to search for roommates by searching for a roommate to stay together on an existing smart-phone, filtering it by prioritizing it with various conditions. We hope that this study will help to revitalize the domestic real estate market and will be used as basic data for the rapid growth of single-person household services.

圓周狀슬라이스의 오-븐건조법에 의한 함수율의 圓盤내 방사방향분포 추이 평가 (Ⅱ) : 주요 국산 침엽수재를 중심으로 For some of domestic softwoods

이남호,Li, Chengyuan,최준호,황의도,진영문 한국목재공학회 2004 목재공학 Vol.32 No.2

본 연구는 주요 국산 침엽수재 원반에서 채취한 두께 3 ㎜의 圓周狀슬라이스를 오-븐에서 급속 건조하면서 각 원반내 함수율의 방사방향 분포추이를 조사하기 위하여 수행하였다. 소나무의 경우 건조가 진행됨에 따라 변재부는 매우 급속한 건조속도로 함수율이 감소한 반면, 심재부는 건조속도가 느려 오히려 생재함수율이 높은 변재부가 심재부보다 먼저 섬유포화점에 도달하였으나, 이러한 분포상태가 장시간 지속되지는 않았다. 낙엽송의 경우 변재부의 생재함수율이 심재부보다 약 3배 가량 높은 분포를 보였으며, 이러한 수분경사 패턴은 평균함수율 약 20%일때 까지 지속되었다. 은행나무의 경우 변재영역 내에서는 매우 고른 생재함수율 분포를 보였으며, 건조가 진행되면서도 어느 정도의 진폭은 존재하였지만 비교적 균일한 함수율 분포를 보였다. 삼나무의 경우 심재부는 생재함수율이 매우 낮아 건조 초기부터 수축이 개시되지만 높은 함수율을 나타내고 있는 변재부에 의해 수축이 억제되므로써 심재영역 또는 이행재 영역에 인장응력이 형성될 것으로 판단된다. 편백나무 변재의 생재함수율은 심재보다 훨씬 낮아 침엽수재의 일반적인 함수율 분포와는 정반대의 분포를 나타내었으며, 이러한 함수율 분포패턴은 평균함수율 약 21%까지도 지속되었다. 측백나무의 경우 변재부의 생재함수율이 심재부보다 약 2배 정도 더 높은 분포를 보였으나, 건조가 진행되면서 이러한 분포는 빠른 속도로 약화되었다. This study was carried out to investigate a radial distribution of moisture contents (MCs) within a log cross section (LC) during ovendrying of 3 mm-thick circumferential slices cut from several domestic softwoods LCs. For Korean red pine, drying rate of sapwood slices during oven-drying represented much higher values than that of heartwood slices, and so sapwood with higher green MC early reached below fiber saturation point (FSP) rather than heartwood did. However, this distribution of moistures did not last for long duration. For Japanese larch, green MC of sapwood was approximately three times higher than that of heartwood. This similar distribution in MC was lasted until about 20% average MC. The MC was around uniform throughout the sapwood of Ginkgo when green and during oven-drying, although it was somewhat fluctuated. For Japanese cedar, the heartwood with so low moistures around FSP would begin to shrink from the beginning stage of drying, but the sapwood above hygroscopic MC prevents the heartwood from shrinking, and consequently, the heartwood or the transition wood goes into tension stress. The results for Japanese cypress showed that the green MCs of the sapwoods were much lower than those for heartwoods, and then this trend was continued until about 20% in average MC. For Chinese thuja, the green MCs of sapwoods were about 2 times as high as those of heartwood, hut this along the radial gradient in MC rapidly hecame gentle during oven-drying.

톨루엔을 포함한 유기용제의 직업적 폭로로 인한 신경내분비계 영향

이채언,이종태,정의화,손혜숙,문덕환,전진호,강정학,이창희,김휘동,김종한,정귀옥 大韓産業醫學會 1995 대한직업환경의학회지 Vol.7 No.2

Long term occupational exposure to solvent mixtures may cause adverse effects to the central nervous system with neurobehavioral symptoms. And some organic slovents have been suggested to cause impairment of tuberoinfundibular dopaminergic activity and neurochemical mechanisms controlling pituitary secretion. For the purpose of assessing neuroendocrine effects in occupational solvents exposure, hormonal study settings (shoes-manufacturing industry & fishing products industry) and compared with nonexposed controls(33 men, 85 women). Male workers exposed to solvent mixtures had significantly lower plasma level of follicle-stimulating hormone(FSH) than nonexposed male controls. While female workers exposed to solvent mixtures had significantly lower plasma levels of growth hormone(GH), and thyroid-stimulating hormone(TSH) than nonexposed female controls. The results of significant decrease in plasma concentrations of pituitary hormones(FSH, GH, and TSH) in workers exposed solvent mixtures indicate that occupational exposure to solvent mixtures may induce neuroendocrine effects through an effect on hypothalamic pituitary axis.

담관 결찰 시 혈장 빌리루빈 농도와 GPT 활성도의 ICG 농도에 대한 상관관계

배진우,이태의 건국대학교 의과학연구소 1998 건국의과학학술지 Vol.8 No.-

Plasma clearance rate of indocyanine green (ICG) is the most important parameter to evaluate the hepatic reserve function for liver resection. To study the relationship between ICG concentration and bilirubin concentration or GPT activity in plasma, we determined these parameters before and after the ligation of bile duct. we ligated the bile duct of rats to induce hyperbilirubinemia and high GPT activity. Before and after the ligation (one day. three days. or fourteen days). we sampled 0.5 ml blood from portal vein to determine the concentration of bilirubin and GPT activity. After removing the ligation. we injected indocyanine green (0.5 mg/kg, 0.5 mg/ml) for 30 seconds through portal vein and sampled 0.5 ml of blood from the abdominal vein to determine ICG concentration after 15 minutes. From these data, we calculated the correlation coefficient. We calculated statistical significance of these parameters of different days after the ligation and the significance between two correlation coefficients. We confirmed the linearity too. All of these parameters were significantly higher than those before ligation(p<0.05). However GPT activity showed peaks after one day, while the concentration of bilirubin and ICG showed peaks after 3 days. The correlation coefficient was 0.884 between the concentration of ICG and bilirubin, but 0.721 between the concentration of ICG and GPT activity. These correlation showed significant linearity with p<0.001 and significant difference with p<0.05. These results suggest that ICG clearance can be negatively influenced by bilirubin concentration more than by GPT activity in the plasma. Therefore, care should be taken in determining the hepatic reserve function by ICG clearance rate for patients with hyperbilirubinemia.

CKD-602, a topoisomerase I inhibitor, induces apoptosis and cell-cycle arrest and inhibits invasion in cervical cancer

Lee, Sungha,Ho, Jung Yoon,Liu, Jing Jing,Lee, Hyewon,Park, Jae Young,Baik, Minwha,Ko, Minji,Lee, Seon Ui,Choi, Youn Jin,Hur, Soo Young BioMed Central 2019 Molecular medicine Vol.25 No.-

<P><B>Background</B></P><P>Cervical cancer is the third most common gynecological malignancy. Conventional treatment options are known to be ineffective for the majority of patients with advanced or recurrent cervical cancer. Therefore, novel therapeutic agents for cervical cancer are necessary. In this study, the effects of CKD-602 in cervical cancer were investigated.</P><P><B>Methods</B></P><P>Three established human, immortalized, cervical cancer cell lines (CaSki, HeLa and SiHa) were used in this study. Following treatment with CKD-602, apoptosis was quantified using fluorescein isothiocyanate Annexin V-FITC and propidium iodide (PI) detection kit and cell cycle analysis was analyzed using fluorescence activated cell sorting (FACS). Transwell chambers were used for invasion assays. Western blot assay was performed to analyze proteomics. CaSki cells were subcutaneously injected into BALB/c-nude mice and cervical cancer xenograft model was established to elucidate the antitumor effect of CKD-602 in vivo.</P><P><B>Results</B></P><P>Treatment with CKD-602 induced apoptosis and increased expression of the enzyme PARP, cleaved PARP, and BAX. In addition, expression of phosphorylated p53 increased. Cell cycle arrest at G2/M phase and inhibition of invasion were detected after treatment with CKD-602. A significant decrease in cervical cancer tumor volume was observed in this in vivo model, following treatment with CKD-602.</P><P><B>Conclusions</B></P><P>This is the first report of CKD-602 having an antitumor effect in cervical cancer in both an in vitro and in vivo models. The results of this study indicate that CKD-602 may be a novel potential drug, targeting cervical cancer, providing new opportunities in the development of new therapeutic strategies.</P><P><B>Electronic supplementary material</B></P><P>The online version of this article (10.1186/s10020-019-0089-y) contains supplementary material, which is available to authorized users.</P>

Dihydrobenzofuran Norlignans from the Leaves of Cedrela sinensis A. Juss

Lee, Ik-Soo,Kim, Hong-Jin,Youn, Ui-Jung,Chen, Quan-Cheng,Kim, Jin-Pyo,Ha, Do Thi,Ngoc, Tran Minh,Min, Byung-Sun,Lee, Sang-Myung,Jung, Hyun-Ju,Na, Min-Kyun,Bae, Ki-Hwan WILEY-VCH Verlag 2010 Helvetica chimica acta Vol.93 No.2

<P>Two new norlignans, cedralins A (1) and B (2), were isolated from the leaves of Cedrela sinensis. Their structures were established by extensive spectroscopic studies and chemical evidence. The absolute configurations of these compounds were determined by comparing their CD spectra with those of known compounds. In addition, their in vitro cytotoxic activity against two human-cancer cell lines was evaluated.</P> <B>Graphic Abstract</B> <P> <img src='wiley_img/0018019X-2010-93-2-HLCA200900180-content.gif' alt='wiley_img/0018019X-2010-93-2-HLCA200900180-content'> </P>

Blue-Shifting Intramolecular Charge Transfer Emission by Nonlocal Effect of Hyperbolic Metamaterials

Lee, Kwang Jin,Lee, Yeon Ui,Fages, Fré,dé,ric,Ribierre, Jean-Charles,Wu, Jeong Weon,D’Alé,o, Anthony American Chemical Society 2018 NANO LETTERS Vol.18 No.2

<P>Metallic nanostructures permit controlling various photophysical processes by coupling photons with plasmonic oscillation of electrons confined in the tailored nanostructures. One example is hyperbolic metamaterial (HMM) leading to an enhanced spontaneous emission rate of emitters located nearby. Noting that emission in organic molecules is from either pi-pi* or intramolecular charge-transfer (ICT) states, we address here how HMM modifies ICT emission spectral features by comparing them with a spectral shift dependent on the local polarity of the medium. The 7.0 nm blue shift is observed in ICT emission from 4-dicyanomethylene-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran dispersed into a polymer matrix prepared on HMM multilayered structure, while no spectral shift is observed in pi-pi* emission from perylene diimide. In the frame of the Lippert-Mataga formalism, the blue shift is explained by the HMM nonlocal effects resulting from 8% decrease in refractive index and 18% reduction in dielectric permittivity. This phenomenon was also shown in a hemi-curcuminoid borondifluoride dye yielding 15.0 nm blue shift. Such a capability of spectral shift control in films by HMM structure opens new prospects for engineering organic light-emitting devices.</P>

Simple, rapid, and accurate malaria diagnostic platform using microfluidic-based immunoassay of Plasmodium falciparum lactate dehydrogenase

Lee Wang Sik,강태준,Kwak Kyung Jin,박경숙,이소연,Lee Ui Jin,Shin Yong Beom,Jeong Jinyoung 나노기술연구협의회 2020 Nano Convergence Vol.7 No.13

This work reports on a rapid diagnostic platform for the detection of Plasmodium falciparum lactate dehydrogenase (PfLDH), a representative malaria biomarker, using a microfluidic microplate-based immunoassay. In this study, the microfluidic microplate made it possible to diagnose PfLDH with a small volume of sample (only 5 μL) and short time (< 90 min) compared to conventional immunoassays such as enzyme-linked immunosorbent assay (ELISA). Moreover, the diagnostic performance of PfLDH showed high sensitivity, specificity, and selectivity (i.e., 0.025 pg/μL in phosphate-buffered saline and 1 pg/μL in human serum). The microfluidic-based microplate sensing platform has the potential to adapt simple, rapid, and accurate diagnoses to the practical detection of malaria.

Standards for recognition and approval rate of occupational cerebro-cardiovascular diseases in Korea

Ui-Jin Kim,Won-Jun Choi,Seong-Kyu Kang,Wanhyung Lee,Seunghon Ham,Junhyeong Lee,Yongho Lee,Eunseun Han,Sanghyuk Lee,Yongkyu Kim,Inah Kim 대한직업환경의학회 2022 대한직업환경의학회지 Vol.34 No.-

Microstructure and Pattern Size Dependence of Copper Corrosion in Submicron-Scale Features

Lee, Ui-hyoung,Jeon, Hyoung Jin,Kang, Tak,Sohn, Hun-Joon,Oh, Kyu Hwan,Her, Eun Kyu,Han, Heung Nam,Lee, H. W.,Kim, Insoo,Kim, Donggyu,Lee, Sung-Keun,Lee, Hyo-Jong The Electrochemical Society 2011 Journal of the Electrochemical Society Vol.158 No.5