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Lai Thi Ngoc Huyen,홍석주,TranQuangTrung,Montri Meeseepong,김아리,이내응 한국바이오칩학회 2023 BioChip Journal Vol.17 No.1
Polydimethylsiloxane (PDMS) has been widely used for the rapid prototyping of microfluidic devices for biosensor cartridges. However, using PDMS to prototype capillary-driven microfluidic devices is often limited by the difficulty of maintaining the surface energy of surface-treated PDMS for an extended period in addition to the degradation of the biosensing elements during the bonding process at elevated temperature. Herein, prototyping of a flexible capillary microfluidic channel (FCMC) device based on the room-temperature bonding of the surface energy-modified PDMS (m-PDMS) microfluidic channel and a thermoplastic lid, polymethylmethacrylate (PMMA), is introduced for prolonged control of passive liquid flow characteristics. The m-PDMS was fabricated by blending polydimethylsiloxane-ethylene oxide (60–70%) block copolymer (PDMS-b-PEO) additive with pre-PDMS, of which the water contact angles could be controlled between 38.5° and 78.5° by adjusting the ratio of the two components. Room-temperature bonding of the m-PDMS and PMMA sheets functionalized by 3-glycidoxypropyltrimethoxysilane and aminopropyltriethoxysilane, respectively, was introduced to fabricate the FCMC devices via the formation of a stable linker epoxy-amine without the requirement of elevated temperatures. The FCMC device possessed longevity to passively drive liquid in the channel for 2 months under ambient conditions due to the prolonged stable hydrophilicity of m-PDMS. The proposed approaches provide great potential for prototyping passive microfluidic devices for biosensor cartridge applications.
Thuy Kieu Truong,T. N. T. Nguyen,TranQuangTrung,손일융,김덕진,정진혁,이내응 한국물리학회 2014 Current Applied Physics Vol.14 No.5
In this study, the reduced graphene oxide field-effect transistor (rGO FET) with indium tin oxide (ITO) extended gate electrode was demonstrated as a transducer for proton sensing application. In this structure, the proton sensing area of the ITO extended gate electrode is isolated from the active area of the rGO FET. The proton sensing properties based on the rGO FET transducer were analyzed. The rGO FET device with encapsulation by a tetratetracontane (TTC) layer showed good stability in electrolytic solutions. The device showed an ambipolar behavior with shifts in Dirac point as the pH of the electrolyte is varied. The pH sensitivity based on the Dirac point shift as a sensing parameter was about 43e50 mV/pH for a wide range of pH values from 2 to 12. The ITO extended gate rGO FET may be considered a potential transducer for sensing of Hþ in electrolytes. Its sensing area can be modified further for various ions sensing applications.
Venu Reddy,K.K.C. Satish Babu,Sri Ramulu Torati,엄윤지,TranQuangTrung,이내응,김철기 한국공업화학회 2018 Journal of Industrial and Engineering Chemistry Vol.63 No.-
The development of environmentally benign, low-processing and low-cost approaches to the large-scale preparation of advanced nanomaterials based on the use of biological materials is currently attracting great interest. Here, we report the discovery that aqueous honey solutions reduce graphene oxide in a low-cost and an eco-friendly manner, yielding highly water dispersive functionalized reduced graphene sheets. The roles of honey in the reduction of graphene oxide of as-prepared graphene are demonstrated. The possible mechanism for the de-epoxidation of graphene oxide is elucidated. The fabricated a honey-reduced graphene oxide-based field-effect transistor exhibited ambipolar transfer characteristics, thereby demonstrating that the developed material may therefore have applications in electronic devices and sensors.