Cloning and structure of a histocompatibility class IIA gene (Lelo-DAA) in Chinese longsnout catfish (Leiocassis longirostris)

Tong Shen,Jianming Li,Xiaoshun He,Meiling Lei,Jingru Wang,Xiuming Li 한국유전학회 2014 Genes & Genomics Vol.36 No.6

Here, the major histocompatibility complex(MHC) class II alpha chain gene in the Chinese longsnoutcatfish (Leiocassis longirostris) was characterized throughcloning, sequencing, polymorphism analysis, and expressionpatterns in various tissues. The full-length LeloDAAcDNA comprises 1,114 bp with a 50-UTR region of 79 bp,an open reading frame of 714 bp and a 30-UTR of 302 bp. The deduced protein sequence shows the followingimportant features: leader peptide, a1, a2, and CP/TM/CYT regions. Using long PCR techniques, the genomicsequence was further identified to be 2,093 bp in length,containing four exons and three introns. Three class IIAalleles were identified from four individuals. Two differentalleles observed (at most) in each individual suggest theexistence of a single locus of class IIA gene in the Chineselongsnout catfish genome. This locus is polymorphic andmost of the amino acidic changes occurred in the a1domain containing the peptide-binding region. Lelo-DAAmRNA expression was mainly found in the intestine, gills,spleen, head kidney and liver; minor expression wasdetected in the stomach, skin, heart and muscle. Our resultsyield insight into Chinese longsnout catfish T cell immuneresponses and will aid future work on the genetic status ofthis economically important species.

Eremophilane Sesquiterpenoids from Farfugium japonicum

Shen, Tong,Yang, Xia,Wang, Xiu Ru,Row, Kyung-Ho Korean Chemical Society 2011 Bulletin of the Korean Chemical Society Vol.32 No.1

Eremophilane Sesquiterpenoids from Farfugium japonicum

Tong Shen,Xia Yang,Xiu Ru Wang,노경호 대한화학회 2011 Bulletin of the Korean Chemical Society Vol.32 No.1

Refining and Validating a Two-stage and Web-based Cancer Risk Assessment Tool for Village Doctors in China

Shen, Xing-Rong,Chai, Jing,Feng, Rui,Liu, Tong-Zhu,Tong, Gui-Xian,Cheng, Jing,Li, Kai-Chun,Xie, Shao-Yu,Shi, Yong,Wang, De-Bin Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.24

The big gap between efficacy of population level prevention and expectations due to heterogeneity and complexity of cancer etiologic factors calls for selective yet personalized interventions based on effective risk assessment. This paper documents our research protocol aimed at refining and validating a two-stage and web-based cancer risk assessment tool, from a tentative one in use by an ongoing project, capable of identifying individuals at elevated risk for one or more types of the 80% leading cancers in rural China with adequate sensitivity and specificity and featuring low cost, easy application and cultural and technical sensitivity for farmers and village doctors. The protocol adopted a modified population-based case control design using 72, 000 non-patients as controls, 2, 200 cancer patients as cases, and another 600 patients as cases for external validation. Factors taken into account comprised 8 domains including diet and nutrition, risk behaviors, family history, precancerous diseases, related medical procedures, exposure to environment hazards, mood and feelings, physical activities and anthropologic and biologic factors. Modeling stresses explored various methodologies like empirical analysis, logistic regression, neuro-network analysis, decision theory and both internal and external validation using concordance statistics, predictive values, etc..

Multi-RIS Aided 3D Secure Precise Wireless Transmission

Tong Shen,Wenlong Cai,Yan Lin,Shuo Zhang,Jinyong Lin,Feng Shu,Jiangzhou Wang 한국통신학회 2022 Journal of communications and networks Vol.24 No.5

In this paper, multiple reconfigurable intelligent surfaces (RIS) aided secure precise wireless transmission (SPWT) schemes are proposed in the three-dimensional (3D) wire- less communication scenario. Unavailable direct path channels from transmitter to receivers are considered when the di- rect paths are obstructed by obstacles. Then, multiple RISs are utilized to achieve SPWT through the reflection path among transmitter, RISs and receivers in order to enhance the communication performance and energy efficiency simulta- neously. First, a maximum-signal-to-interference-and-noise ratio (MSINR) scheme is proposed in a single user scenario. Then, the multi-user scenario is considered where the illegitimate users are regarded as eavesdroppers. A maximum-secrecy-rate (MSR) scheme and a maximum-signal-to-leakage-and-noise ratio (MSLNR) are proposed. The former achieves a better secrecy rate (SR) performance but incurs a higher complexity. The latter has a lower complexity than the MSR scheme with an SR performance loss. Simulation results show that both single- user scheme and multi-user scheme can achieve SPWT which transmits confidential message precisely to location of desired users. Moreover, MSLNR scheme has a lower complexity than the MSR scheme, while the SR performance is close to that of the MSR scheme.

한·중·일 상호 문화의 차이에 대한 드라마 가족서사분석 - <꽃보다 남자>의 재제작 판을 중심으로 -

심동 ( Shen Tong ),이승조 ( Lee Seungjo ) 인하대학교 교육연구소 2017 교육문화연구 Vol.23 No.5

본 연구는 한·중·일에서 인기를 얻었던 드라마 <꽃보다 남자>의 각국별 재제작 판에서 가족서사를 중심으로 드러나는 문화적 차이를 살펴보았다. <꽃보다 남자>는 빈부 격차가 현격한 두 가족을 배경으로 자녀들의 사랑 이야기가 전개되기 때문에 물질적 가치를 둘러싼 문화적 차이가 묘사될 것으로 기대하였다. 연구 방법은 이야기 전체의 흐름을 따라가는 통합체 분석과 대립적인 관계를 조명하는 계열체 분석을 이용하였다. 분석 결과, 가족서사에 표현된 부유층과 서민층의 간극은 한국판에서 가장 크고, 일본판과 중국판의 순서대로 감소하는 것으로 나타났다. 이러한 간극의 차이는 부유층과 서민층의 욕망이 충돌하는 정도나 계층 상승의 장벽이 묘사되는 문화적 현상의 차별화로 표출되었다. 본 연구는 <꽃보다 남자>와 같이 동일한 이야기의 재제작 판이 한·중·일 삼국 간의 문화적 동질성과 차별성을 비교하고 이해하는 질료를 제공함을 보여준다. This study examined the cultural differences revealed in family narratives of the reproduction versions of < Boys Over Flowers >, which was popular in Korea, China and Japan. We expected that cultural differences relative to material values will be portrayed through < Boys Over Flowers > because the love story of young people develops within the background of two families whose gap between rich and poor is remarkable. The research method employed were both the integrated analysis that followed the whole story and the sequential analysis which focused on the opposing relationship. The results show that the gap between the rich and poor family narrative structure is the largest in the Korean version, and decreases in the order of the Japanese and the Chinese version. The gaps were expressed by the different cultural phenomenon depicting the degree of conflict between the rich and poor people 's desires and the barrier against mobility to the upper class. This study shows that the remakes of the same story, such as “Boys Over Flowers,” provides the foundation that we can compare and understand cultural homogeneity and differentiation between the three countries.

Association Between Gestational Diabetes Mellitus and Subsequent Risk of Cancer: a Systematic Review of Epidemiological Studies

Tong, Gui-Xian,Cheng, Jing,Chai, Jing,Geng, Qing-Qing,Chen, Peng-Lai,Shen, Xin-Rong,Liang, Han,Wang, De-Bin Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.10

Purpose: This study aimed at summarizing epidemiological evidence of the association between gestational diabetes mellitus (GDM) and subsequent risk of cancer. Materials and Methods: We searched Medline, Embase, Cancer Lit and CINAHL for epidemiological studies published by February 1, 2014 examining the risk of cancer in patients with history of GDM using highly inclusive algorithms. Information about first author, year of publication, country of study, study design, cancer sites, sample sizes, attained age of subjects and methods used for determining GDM status were extracted by two researchers and Stata version 11.0 was used to perform the meta-analysis and estimate the pooled effects. Results: A total of 9 articles documented 5 cohort and 4 case-control studies containing 10,630 cancer cases and 14,608 women with a history of GDM were included in this review. Taken together, the pooled odds ratio (OR) between GDM and breast cancer risk was 1.01 (0.87-1.17); yet the same pooled ORs of case-control and cohort studies were 0.87 (0.71-1.06) and 1.25 (1.00-1.56) respectively. There are indications that GDM is strongly associated with higher risk of pancreatic cancer (HR=8.68) and hematologic malignancies (HR=4.53), but no relationships were detected between GDM and other types of cancer. Conclusions: Although GDM increases the risk of certain types of cancer, these results should be interpreted with caution becuase of some methodological flaws. The issue merits added investigation and coordinated efforts between researchers, antenatal clinics and cancer treatment and registration agencies to help attain better understanding.

Effects of pores and temperature on mechanics of gold nanowires using molecular dynamics

Shen-Yung Lin,Tong Hong Wangs,Te-Hua Fang,Wen-Li Chen 한국물리학회 2010 Current Applied Physics Vol.10 No.1

The deformation mechanisms of gold nanowires with different nanopores under tension were simulated by molecular dynamics (MD). The stress–strain curves varied from different porous defects, and the tension caused dislocations to take place and slip along plane (1 1 1). Moreover, the tensile strength of the nanoporous monocrystalline gold was decreased when the simulated temperature increased. The stress concentrations factors of porous nanowires were calculated, and it was found that there was a great influence of size and model effects on the stress concentration factors.

A Study on the Synergistic Effects of Online and Offline Integration Performance of Rainbow Shares

Shen Linlin,Wang Tong 한중경제문화학회 2018 한중경제문화연구 Vol.11 No.-

In the new era of rapid development of e-commerce and increasingly convenient mobile payment, the online and offline business model is increasingly becoming an important direction for the transformation and upgrading of retail enterprises, affecting the management and investment decisions of retail enterprises. Whether online and offline integration has a synergistic effect on physical retail enterprises remains to be seen. This paper analyzes and evaluates the performance of online and offline integration of Rainbow Shares by using the catastrophe progression method combined with the entropy method. The combination of these two methods provides new ideas for research in retail development.

Association Between Pancreatitis and Subsequent Risk of Pancreatic Cancer: a Systematic Review of Epidemiological Studies

Tong, Gui-Xian,Geng, Qing-Qing,Chai, Jing,Cheng, Jing,Chen, Peng-Lai,Liang, Han,Shen, Xing-Rong,Wang, De-Bin Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.12

This study aimed to summarize published epidemiological evidence for the relationship between pancreatitis and subsequent risk of pancreatic cancer (PC). We searched Medline and Embase for epidemiological studies published by February $5^{th}$, 2014 examining the risk of PC in pancreatitis patients using highly inclusive algorithms. Information about first author, year of publication, country of study, recruitment period, type of pancreatitis, study design, sample size, source of controls and attained age of subjects were extracted by two researchers and Stata 11.0 was used to perform the statistical analyses and examine publication bias. Odds ratios (ORs) with 95% confidence intervals (CIs) were calculated with the random effects model. A total of 17 articles documenting 3 cohort and 14 case-control studies containing 14,667 PC cases and 17,587 pancreatitis cases were included in this study. The pooled OR between pancreatitis and PC risk was 7.05 (95%CI: 6.42-7.75). Howeever, the pooled ORs of case-control and cohort studies were 4.62 (95%CI: 4.08-5.22) and 16.3 (95%CI: 14.3-18.6) respectively. The risk of PC was the highest in patients with chronic pancreatitis (pooled OR=10.35; 95%CI: 9.13-11.75), followed by unspecified type of pancreatitis (pooled OR=6.41; 95%CI: 4.93-8.34), both acute and chronic pancreatitis (pooled OR=6.13; 95%CI: 5.00-7.52), and acute pancreatitis (pooled OR=2.12; 95%CI: 1.59-2.83). The pooled OR of PC in pancreatitis cases diagnosed within 1 year was the highest (pooled OR=23.3; 95%CI: 14.0-38.9); and the risk in subjects diagnosed with pancreatitis for no less than 2, 5 and 10 years were 3.03 (95%CI: 2.41-3.81), 2.82 (95%CI: 2.12-3.76) and 2.25 (95%CI: 1.59-3.19) respectively. Pancreatitis, especially chronic pancreatitis, was associated with a significantly increased risk of PC; and the risk decreased with increasing duration since diagnosis of pancreatitis.