한·중 여성소설의 전쟁 체험과 여성 주체성 형성

방문정(Pang Wen-ting) 어문연구학회 2017 어문연구 Vol.93 No.-

이 논문은 한국 작가 박완서의 그 산이 정말 거기 있었을까와 중국 작가 장졔의 무자를 대상으로 여성들의 전쟁 체험과 여성의식의 변화 과정, 주체성의 형성 등을 살펴보았다. 두 작품 모두 여성의 시각으로 전시 여성들이 직면해야 하는 위기와 문제, 그리고 고난을 적극적으로 해결하고 극복하면서 여성으로서의 삶에 대해 진지하게 성찰하는 모습을적절히형상화하고있다. 비록나라는다르지만, 두작품에반영된전시여성의삶을통해 전쟁이 여성의 삶에 끼치는 영향과 여성 정체성 찾기에 나타난 보편성과 공통점을 확인할 수 있었다. 구세대 여성들의 경우, 전쟁의 고통스런 경험은 기성의 관념을 강화시키기도 하고 또역으로 분열시키기도 한다. 즉 구세대 여성들이 체화하고 있었던 가부장적 이념이 남성중심적사상으로강화되어 등장하기도하고, 또여성의공적 영역에서의사회생활을인정하는 모습을 보임으로써 가부장적 이념의 분열을 드러내기도 하였다. 다른 한편 전쟁은 여성에게 가족의 유지와 생계 문제 해결을 요구함으로써 공적 공간 으로의진출계기를마련해주었으며이를통해여성은독립한인간으로서의자아를찾아가는 기회를 가질 수 있었다. 결국 개인의 성장과 주체성의 구성은 사회가 제공하는 경험의요소와 인간내면의주체의식이서로호응되면서 발전해 간다는 것을 확인할 수있었다. 두작품은전쟁의계기로다양한경험을하게된여성들이자신의힘으로삶의어려움을 극복하고 경제적 독립을 통해 인격적 독립까지도 획득하는 과정을 보여주었다. 물론두작품에나타난주체성형성과정의구체적인양상에는차이가 분명존재한다. 그산이정말거기 있었을까에서 주인공 여성은전쟁 중여성 가장이되면서자신의내면을 형성하고자연스럽게 연애과 결혼의 경로를 거친다. 무자의우웨이는 작가가 되면서 가장으로서의 면모를 보이지만, 왜곡된 남성관으로 인하여 두 번에 걸친 결혼에 실패한다. 이러한 차이는 작가의 경험과 의식의 차이로 나타난 것이기도 하지만, 한국과 중국의 전쟁과 근대국가의 건설과정이 서로 달라 나타난 것이기도 하다. 이러한 차이에도 불구하고 한・중 양국의 대표적인 여성작가 박완서와 장졔의 작품에서 전시의 극한 환경 속에 놓인 여성들은 각종 고난을 극복하면서 자기 정체성을 탐구하는 끈질긴 노력을 공통적으로 보여주었다. 이런 측면에서 소설에 나타난 여성 의식의 전개와 변화 발전의 가능성을 확인할 수 있었다.

MUSIC 알고리즘에 의한 레이더 반사단면적 계산법에 관한 연구

방천정(Tian Ting Pang),정중식(Jung-Sik Jeong),박성현(Sung-Hyeon Park),남택근(Taek-Kun Nam),임정빈(Jeong-Bin Yim),안영섭(Young-sup Ahn) 한국항해항만학회 2005 한국항해항만학회 학술대회논문집 Vol.3 No.-

레이더 물표에 대한 반사성능은 RCS(Radar Cross Section)에 의하여 결정된다. 형상이 비교적 간단한 물체에 대해서는 고유함수 접근법에 의하여 RCS를 정확하게 예측할 수 있으나, 해상물표와 같은 복잡한 물표에 대해서는 저주파 및 고주파 산란해석 기법 등을 이용하여 근사적인 해를 찾을 수 밖에 없고 계산적으로도 복잡하다. 본 연구에서는 수신신호의 파라미터를 정도 높게 추정할 수 있는 MUSIC 알고리즘을 이용하여 RCS 값을 근사적으로 구할 수 있는 알고리즘을 제안한다. 제안된 방법에서는 레이더 물표는 산란체의 링으로서 가정되고 레이더 물표로부터 반사된 신호들의 진폭은 통계적 성질을 지니고 분포하게 된다. 결과적으로 제안된 레이더 신호모델에 MUSIC 알고리즘이 적용되고, 레이더 물표의 RCS는 간단한 대수적인 방법으로 계산된다. The detectability of radar depends on RCS(radar cross section). The RCS for complex radar targets may be only approximately calculated by using low-frequency or high-frequency scattering methods, while the RCS for simple radar targets can be exactly obtained by applying an eigen-function method. However, the conventional methods for calculation of RCS are computationally complex. We propose an approximation method for RCS calculation by MUSIC algorithm. In this research, it is assumed that the radar target is considered as a ring of scatterers. The amplitudes of scatterers may be statistically distributed. As the result, the radar signal model is proposed to use MUSIC, and the RCS is calculated by a simple linear algebraic method.

DC-DC Converter with Self-Regulated Output Voltage Control Scheme for Multiple-String Dimmable LED Driver Control

Pang-Jung Liu,Yu-Chi Hsu,Ting-Yu Wei,Zhi-Yuan Hong 전력전자학회 2019 ICPE(ISPE)논문집 Vol.2019 No.5

This paper presents a dc-dc converter with selfregulated output voltage (SROV) and phase shift PWM (PSPWM) control methods for multiple LED strings. The LED driver is composed of a boost converter and dimmable current balancing regulators (CBRs). Compared with traditional linear current regulator, the CBR is adopted to reduce power consumption. To keep a designed constant voltage on the CBRs, the output voltage of the boost converter is dynamically adjusted with the SROV control method. It results in high efficiency and current balance of the CBRs and prevents output voltage oscillation. The PSPWM control is employed to mitigate the output current variation supplied by the boot converter, leading to smaller output transient ripple when the PWM dimming signals are changed. The CBRs and control circuits were fabricated with a 0.35-μm standard CMOS technology. The experimental results demonstrate the theoretical analysis of the proposed LED driver.

Development of Automatic Supplementary Lighting System for Greenhouses

( Shih Fu-pang ),( Lin Meng-ting ),( Lee Hsieh-chih ),( Hsieh Kuang-wen ) 한국농업기계학회 2018 한국농업기계학회 학술발표논문집 Vol.23 No.1

To solve the agricultural damages caused by the climate change, this study is developed to build an automatic supplementary lighting platform for plant factories. The platform mainly uses aluminum as materials. The lighting strategy will depend on the DPI. During the day, platform parked at the original position and uses quantum sensor to accumulate the daylight. At night, it moved to the supplementary lighting area and provides lighting to plants. The platform is operated in cooperation with a PLC control system, and uses RFID and limit switch as a local positioning system at plant factories. In supplementary lighting area, lifting system detects the height of plants to adjust the level of lampshade accordingly. The study operated 10 times movement experiments, after first 5 times calibration, the success rate of last 5 times moving positioning is 93%, and the success rate of 10 times lifting experiments is 98%. The platform can provide an average of 354 μmol /㎡ /s light intensity within the distance of 10cm from the plants, and 3.27 μmol CO₂ / ㎡ / s if it is within the photosynthesis characteristic of lettuce. Based on the results of two-week experiment, it can be confirmed that supplementary lighting is able to provide sufficient lighting to plants during the night, and reach DPI standard of each supplementary lighting area.

Coexistence of osteoporosis, sarcopenia and obesity in community-dwelling adults – The Yishun Study

Benedict Wei Jun Pang,Shiou-Liang Wee,Kenneth Kexun Chen,Lay Khoon Lau,Khalid Abdul Jabbar,Wei Ting Seah,Daniella Hui Min Ng,Queenie Lin Ling Tan,Mallya Ullal Jagadish,Tze Pin Ng 대한골다공증학회 2021 Osteoporosis and Sarcopenia Vol.7 No.1

Objectives: To 1) report prevalence of ‘osteosarcopenia’ (OS) and osteosarcopenic obesity (OSO) entities using evidence-based diagnostic techniques and definitions, 2) examine if OSO offers additional predictive value of functional decline over its components, and 3) identify associated factors in a multi-racial Southeast Asian population. Methods: We performed a cross-sectional study of a representative sample of 542 community-dwelling adults (21e90 years old), and assessed anthropometry, cognition, functional performance, and selfreport sociodemographic, health and lifestyle questionnaires. Low muscle mass, and the Asian Working Group for Sarcopenia (AWGS) 2019 criteria, were used to assess sarcopenia. Obesity was defined using percentage body fat and fat mass index. Osteopenia/osteoporosis was determined using lumbar spinal bone mineral density. Associated factors were examined using logistic regression, and OSO’s value investigated using linear regressions with functional performance. Results: OS and OSO prevalence were 1.8% and 0% (21e59 years), 12.9% and 2.8% ( 60 years), 17.3% and 4.1% ( 65 years), and 25.5% and 7.0% (75 years), respectively. OSO entity as defined was not a significant predictor (P > 0.05) and did not improve explanations for functional decline over sarcopenia or sarcopenic obesity. Age, sex, race and body mass index (BMI) were associated with OS, while age, sex, race and alcoholism were associated with OSO. Conclusions: Our results do not support OSO as a distinct entity in relation to functional decline. Aside from biological age, sex, and race, amenable lifestyle factors such as BMI and alcohol intake are important variables that can influence the co-existence of osteopenia/osteoporosis, sarcopenia and obesity.

Identification of lead inhibitors targeting influenza A virus nucleoprotein through surface plasmon resonance screening

Chun-Yeung Lo,Sze-Ting Choi,Olive Tin-Wai Li,Jacky Chi-Ki Ngo,David Chi-Cheong Wan,Leo Lit-Man Poon,Pang-Chui Shaw1 한국구조생물학회 2015 Biodesign Vol.3 No.3

Currently, many strains of influenza A virus have developed resistance against anti-influenza drugs, and it is essential to find new chemicals to combat this virus. The viral nucleoprotein (NP) is a major component of the ribonucleoprotein (RNP) complex for the transcription and replication of the virus. In this study, we have employed surface plasmon resonance direct binding screening on the influenza A NP and found a hit compound 16 that can subdue influenza RNP activities. Subsequently, two analogs (compounds 55 & 58) from compound 16 were identified which inhibit RNP activities of various influenza A subtypes and viral growth at micromolar levels. These analogs were also shown to directly interact with NP, with KD 12.0±1.25 and 41.6±1.93 μM respectively by surface plasmon resonance assay.

Generation of Buffalo Mammary Epithelial Cells with Targeted Knockout of 18s rDNA by a CRISPR/Cas9 Adenovirus System

Peng Zhu,An-Qin Duan,Ting-Xian Deng,Xing-Rong Lu,Xiao-Ya Ma,Sha-Sha Liang,Chun-Ying Pang,Xian-Wei Liang 한국생물공학회 2017 Biotechnology and Bioprocess Engineering Vol.22 No.5

In recent years, CRISPR/Cas9 has rapidly become one of the most promising genome editing tools because it is simple and easy to use and cost effective. However, the large size of Cas9 sequences limits its application in clinically promising vectors and it also impacts non-viral transfection. In this study, CRISPR/Cas9 adenovirus vectors that target the buffalo 18s rDNA gene were constructed, transfected into 293 cells for adenovirus packaging, and the adenovirus was used to knockout the 18s rDNA gene in buffalo mammary epithelial cells. The results demonstrated that the CRISPR/Cas9 adenovirus vectors for the buffalo 18s rDNA gene could efficiently target the sites as revealed by the fluorescence reporter system. After amplification, the adenovirus titer of Sn458- 18s1 and Sn458-18s2 reached 1.03 × 109PFU/mL and 1.05 × 109 PFU/mL, respectively. For buffalo mammary epithelial cell infection, the efficiency was 100% when the multiplicity of infection (MOI) 100 PFU/mL. There were 9 mutational clones found in the 20 clones, and the gene mutagenesis rate reached 45%. Of these, 2 clones were 35-bp deleted and 7 clones were 12-bp deleted. These results suggested that the adenovirus system overcame the low transfection efficiency of the buffalo mammary epithelial cells associated with using lipid-based methods or electroporation. Moreover, we preliminary developed an efficient technique for multiple-locus gene targeting at repeated sequences of the buffalo genome.

MiR-183-5p Promotes Proliferation, Metastasis and Angiogenesis in Breast Cancer Cells through Negatively Regulating Four and a Half LIM Protein 1

Yi Li,Qing'an Zeng,Jiliang Qiu,Ting Pang,Fenglian Ye,Lin Huang,Xuexia Zhang 한국유방암학회 2020 Journal of breast cancer Vol.23 No.4

Purpose: Four and a half LIM protein 1 (FHL1) is involved in breast cancer (BC) development, but the regulatory mechanism involved remain unclear. In the present study, we examined the role of FHL1 in BC development. Methods: The expression of FHL1, miR-183-5p, and miR-96-5p in BC tissues was analyzed using StarBase analysis. FHL1 expression in BC tissues, a normal human breast epithelial cell line, and BC cell lines was detected using quantitative reverse transcription polymerase chain reaction (qRT-PCR). The relationship between FHL1 and miR-183-5p/miR-96-5p was analyzed via Pearson's rank correlation, TargetScan, and a dual-luciferase reporter assay. BT549 and MDA-MB-231 cells were transfected with either FHL1 and miR-183-5p mimics, or siFHL1 and a miR-183-5p inhibitor, respectively. The viability, colony number, migration, invasion, and tube length of BT549 and MDA-MB-231 cells were examined using cell counting kit-8, colony formation, wound-healing, Transwell, and tube formation assays, respectively. The levels of FHL1, vascular endothelial growth factor (VEGF), p53, E-cadherin, N-cadherin, and vimentin were quantified using western blotting and qRT-PCR. Results: FHL1 expression was downregulated in BC tissues and cells, whereas miR-183-5p and miR-96-5p were upregulated in BC tissues (negative correlation with FHL1 expression). FHL1 overexpression inhibited the viability, colony number, migration, and invasion of BC cells and the expression of VEGF, N-cadherin, and vimentin, and increased the expression of FHL1, p53, and E-cadherin in BT549 cells. Furthermore, a miR-183-5p mimic reversed these effects of FHL1 overexpression, whereas FHL1 silencing caused opposite results to those observed in MDA-MB-231 cells; however, this was reversed by a miR-183-5p inhibitor. Conclusion: Our study suggests that miR-183-5p promotes cell proliferation, metastasis, and angiogenesis by negatively regulating FHL1 in BC.

Prediction of Chemotherapeutic Response in Unresectable Non-small-cell Lung Cancer (NSCLC) Patients by 3-(4,5-Dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium (MTS) Assay

Chen, Juan,Cheng, Guo-Hua,Chen, Li-Pai,Pang, Ting-Yuan,Wang, Xiao-Le Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.5

Background: Selecting chemotherapy regimens guided by chemosensitivity tests can provide individualized therapies for cancer patients. The 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2Htetrazolium, inner salt (MTS) assay is one in vitro assay which has become widely used to evaluate the sensitivity to anticancer agents. The aim of this study was to evaluate the clinical applicability and accuracy of MTS assay for predicting chemotherapeutic response in unresectable NSCLC patients. Methods: Cancer cells were isolated from malignant pleural effusions of patients by density gradient centrifugation, and their sensitivity to eight chemotherapeutic agents was examined by MTS assay and compared with clinical response. Results: A total of 37 patients participated in this study, and MTS assay produced results successfully in 34 patients (91.9%). The sensitivity rates ranged from 8.8% to 88.2%. Twenty-four of 34 patients who received chemotherapy were evaluated for in vitro-in vivo response analysis. The correlation between in vitro chemosensitivity result and in vivo response was highly significant (P=0.003), and the total predictive accuracy, sensitivity, specificity, positive predictive value, and negative predictive value for MTS assay were 87.5%, 94.1%, 71.4%, 88.9%, and 83.3%, respectively. The in vitro sensitivity for CDDP also showed a significant correlation with in vivo response (P=0.018, r=0.522). Conclusion: MTS assay is a preferable in vitro chemosensitivity assay that could be use to predict the response to chemotherapy and select the appropriate chemotherapy regimens for unresectable NSCLC patients, which could greatly improve therapeutic efficacy and reduce unnecessary adverse effects.

Effect of metal oxide partial substitution of V2O5 in V2O5–WO3/TiO2 on selective catalytic reduction of NO with NH3

Qing-mao Zhang,Chong-lin Song,Gang Lv,Feng Bin,Hua-ting Pang,Jin-ou Song 한국공업화학회 2015 Journal of Industrial and Engineering Chemistry Vol.24 No.-

After partial substitution of V2O5 in V2O5–WO3/TiO2 by metal oxide (MxOy, M = Fe, Co, Ni, Cu, Sr, La, and Ce), the NO conversions for the MxOy–V2O5–WO3/TiO2 catalysts (M-VW) showed the following sequence: Co–VW > Fe–VW > Sr-VW Ce-VW La-VW > VW > Ni-VW > Cu-VW. The reduction activities for almost all the M-VW catalysts were enhanced at reaction temperature >400 8C, but only the Co-VW catalyst showed an increased activity at temperature <400 8C. Among the M-VW catalysts tested, the Co-VW sample had the highest catalytic activity with a temperature range of 300–550 8C for more than 90% NO removal at a GHSV of 60 000 h1. Moreover, the Co-VW sample exhibited high space- velocity, H2O and SO2 resistance, and low N2O yield. Co partial substitution for V in the VW led to more Lewis acid sites and Brønsted acid sites, and an obvious increase in the ratio of the adsorbed oxygen to the lattice oxygen from 12.74% for VW to 36.73% for Co-VW. The increased adsorbed oxygen and Lewis and Brønsted acid sites contributed to the improved SCR activity of the Co-VW sample.