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Modified Criteria for Diagnosing “Cognitive Frailty”
Chang Won Won,Yunhwan Lee,Sunyoung Kim,Jinho Yoo,Miji Kim,Tze-Pin Ng,Haena Kim,Sang Joon Son 대한신경정신의학회 2018 PSYCHIATRY INVESTIGATION Vol.15 No.9
The concept of cognitive frailty has recently been proposed by an International Consensus Group as the presence of physical frailty and cognitive impairment [defined using the Clinical Dementia Ratings (CDR)=0.5], without concurrent dementia. However, CDR is difficult to implement and not often available in epidemiologic studies or busy clinical settings, and an alternative to CDR is required. We suggest an alternative definition of cognitive frailty as: 1) physical frailty, 2) more than 1.5 standard deviation below the mean for age-, gender-, and education-adjusted norms on any cognitive function test (e.g., the Montreal Cognitive assessment test, the Alzheimer’s disease assessment scale-cognitive subscale, verbal learning test, Digit Span, Boston Naming Test, Trail Making Test, and Frontal Assessment Battery), and 3) no dependency in instrumental activities of daily living. The redefined criteria for cognitive frailty would be more feasible to implement and thus more applicable in epidemiologic studies and busy clinical settings.
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Coexistence of osteoporosis, sarcopenia and obesity in community-dwelling adults – The Yishun Study
Benedict Wei Jun Pang,Shiou-Liang Wee,Kenneth Kexun Chen,Lay Khoon Lau,Khalid Abdul Jabbar,Wei Ting Seah,Daniella Hui Min Ng,Queenie Lin Ling Tan,Mallya Ullal Jagadish,Tze Pin Ng 대한골다공증학회 2021 Osteoporosis and Sarcopenia Vol.7 No.1
Objectives: To 1) report prevalence of ‘osteosarcopenia’ (OS) and osteosarcopenic obesity (OSO) entities using evidence-based diagnostic techniques and definitions, 2) examine if OSO offers additional predictive value of functional decline over its components, and 3) identify associated factors in a multi-racial Southeast Asian population. Methods: We performed a cross-sectional study of a representative sample of 542 community-dwelling adults (21e90 years old), and assessed anthropometry, cognition, functional performance, and selfreport sociodemographic, health and lifestyle questionnaires. Low muscle mass, and the Asian Working Group for Sarcopenia (AWGS) 2019 criteria, were used to assess sarcopenia. Obesity was defined using percentage body fat and fat mass index. Osteopenia/osteoporosis was determined using lumbar spinal bone mineral density. Associated factors were examined using logistic regression, and OSO’s value investigated using linear regressions with functional performance. Results: OS and OSO prevalence were 1.8% and 0% (21e59 years), 12.9% and 2.8% ( 60 years), 17.3% and 4.1% ( 65 years), and 25.5% and 7.0% (75 years), respectively. OSO entity as defined was not a significant predictor (P > 0.05) and did not improve explanations for functional decline over sarcopenia or sarcopenic obesity. Age, sex, race and body mass index (BMI) were associated with OS, while age, sex, race and alcoholism were associated with OSO. Conclusions: Our results do not support OSO as a distinct entity in relation to functional decline. Aside from biological age, sex, and race, amenable lifestyle factors such as BMI and alcohol intake are important variables that can influence the co-existence of osteopenia/osteoporosis, sarcopenia and obesity.
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