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Two new meroterpenoids produced by the endophytic fungus Penicillium sp. SXH-65
Xinhua Sun,Xianglan Kong,Huquan Gao,Tianjiao Zhu,Guangwei Wu,Qianqun Gu,Dehai Li 대한약학회 2014 Archives of Pharmacal Research Vol.37 No.8
Two new meroterpenoids, arisugacins I (1) andJ (2), together with five known meroterpenoids includingarisugacin B (3), arisugacin F (4), arisugacin G (5), territremB (6) and territrem C (7) were isolated from anendophytic fungus Penicillium sp. SXH-65. Their structureswere determined by extensive spectroscopic experimentsand comparison with literature data. Theircytotoxicities were evaluated against Hela, HL-60 andK562 cell lines, and only 3 and 4 exhibited weak cytotoxicitiesagainst Hela, HL-60 and K562 cell lines withIC50 values ranging from 24 to 60 lM.
Zhengmin Yang,Yang Shi,Jiaqi Shuai,Yanlin Li,Tianjiao Sun,Mengjie Chen,Changping Lv 한국원예학회 2021 원예과학기술지 Vol.39 No.5
To protect and identify the varieties of tree peony, DNA fingerprints were constructed and genetic diversity was analyzed with simple sequence repeat markers with tailed primer M13 (TP-M13-SSR) technology in 18 local tree peony varieties in Hunan Province of China. Twenty-four out of 131 pairs of polymorphic primers showing stable amplification and good capillary electrophoresis peaks were selected. The Shannon information indexes (I), polymorphism information contents (PICs), and differentiation rates of eight primer pairs were higher than average. Unweighted pair-group method with arithmetic mean (UPGMA) dendrograms indicated that the genetic similarity coefficients of the 18 Hunan tree peony varieties ranged from 0.57 to 0.86, and Paeonia suffruticosa ‘Ning Xiang Hong’ (0.57) was classified as a separate group. The 18 varieties could be completely distinguished with two pairs of primers. The variety names, flower types, fingerprinting codes, and other information were included in the quick response (QR) code, which provides a basis for the molecular identification of Hunan tree peony varieties. The construction of DNA fingerprinting of tree peony varieties in Hunan is important for its protection.