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Fabrication of Slot-Antenna-Coupled BSCCO Intrinsic Josephson Junctions
Takashi Uchida,Noboru Kawai,Takashi Tachiki 한국물리학회 2006 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.48 No.5I
Coupling intrinsic Josephson junctions with a thin-.lm antenna is an eective method for realizing sensitive detectors and high-power oscillators in the millimeter- and submillimeter- wavelength regions. We investigated using a slot antenna as a thin-.lm antenna and fabricated slot-antenna-coupled Bi2Sr2CaCu2O8+x intrinsic Josephson junctions for 100 GHz millimeter waves. The antenna structure was designed for coupling the antenna ground plane with intrinsic Josephson junctions of a four-terminal con.guration. The ground plane of the antenna also acts as an electrode. Therefore, the ground plane was divided into four electrodes by making four DC cuts and extended electrodes were used to connect the electrodes to intrinsic Josephson junctions. Then, slot-antenna-coupled intrinsic Josephson junctions were fabricated on MgO substrates. The antenna ground plane consisted of a Au .lm. The current-voltage characteristics of the intrinsic Josephson junctions exhibited resistive branches with the critical current of about 1.5 mA at 20 K. Operation of the antenna was con.rmed on the basis of the dierence of 7.8 dB in the irradiation power when the critical current started to be suppressed between the cases with the incident electric .eld respectively parallel and perpendicular to the E-plane of the antenna.
First-principles Molecular-dynamics Study on the Magnetic Structure of Mn3Pt
Takashi Uchida,Nobuyuki Kimura,Yoshiro Kakehashi 한국물리학회 2013 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.62 No.12
A first-principles molecular-dynamics (MD) approach to the magnetic structure of itinerant magnetsis proposed and applied to the magnetic structure of Mn3Pt, which is a three-dimensionalfrustrated magnet with an octahedral configuration of Mn local magnetic moments and exhibitstwo ordered phases at temperatures below the N´eel temperature. The theory is formulated byincorporating the first-principles tight-binding linear muffin-tin orbital Hamiltonian into the MDapproach for itinerant magnets on the basis of the functional integral method and the isothermal MDtechnique, and determines automatically the magnetic structures of itinerant magnets at finite temperatures. Numerical results at 25 K for a 3×3×3 fcc unit cell reveal a triangular-type noncollinearmagnetic structure, which is consistent with the experimentally-proposed magnetic structure of thelow-temperature-ordered phase (D-phase). With increasing temperature in the D-phase region, theamplitude and the thermal average of Mn local moments were found to decrease gradually. The stabilityof the experimentally-suggested magnetic structure of the higher-temperature-ordered phase(F-phase) in Mn3Pt is discussed on the basis of the nonmagnetic ground-state density of states,which shows a sharp sub-peak consisting of the Eg states of Mn at the Fermi energy.
Flow characteristics and rheological properties of propane hydrate slurry
Ryosuke Uchida,Takashi Morimoto,Hiroyuki Kumano 대한설비공학회 2018 대한설비공학회 학술발표대회논문집 Vol.2018 No.6
Propane hydrate is crystalline solids resulting from the arrangement of water molecules linked by hydrogen bonds constituting cages around propane molecules. The propane hydrate slurry is composed of water and fine propane hydrate crystals, and is attracting as transportation and storage medium of the propane. In this study, the flow characteristics and rheological properties of the propane hydrate slurry in a circular tube were investigated. The hydrate volume fraction and the flow rate of the slurry were varied as experimental parameters. As a result, it was found that the pressure drop increases with the solid fraction and the flow rate. Furthermore, in order to evaluate the rheological properties, the relationship between shear stress and shear rate was also discussed. From the results, the propane hydrate slurry could be regarded as a Bingham fluid. Finally, the correlation to predict the apparent viscosity and the yield stress was proposed as a function of the volume fraction. Moreover, it was found that solid phase doesn’t affect the flow characteristics of the hydrate slurry in turbulent flow region.
Ohmachi, Ken,Niitsu, Nozomi,Uchida, Toshiki,Kim, Seok Jin,Ando, Kiyoshi,Takahashi, Naoki,Takahashi, Naoto,Uike, Naokuni,Eom, Hyeon Seok,Chae, Yee Soo,Terauchi, Takashi,Tateishi, Ukihide,Tatsumi, Mitsu American Society for Clinical Oncology 2013 Journal of clinical oncology Vol.31 No.17
<P><B>Purpose</B></P><P>Effective and less aggressive therapies are required for patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL) who are not eligible for or have undergone autologous stem-cell transplantation (ASCT). The present phase II study assessed the efficacy and safety of bendamustine plus rituximab (BR) in this population.</P><P><B>Patients and Methods</B></P><P>Patients with relapsed or refractory DLBCL treated with one to three prior chemotherapy regimens received rituximab 375 mg/m<SUP>2</SUP> intravenous (IV) infusion on day 1 and bendamustine 120 mg/m<SUP>2</SUP> by IV infusion on days 2 and 3 of each 21-day cycle for up to six cycles. The primary end point was overall response rate (ORR), and the secondary end points were complete response (CR) rate, progression-free survival (PFS), and safety.</P><P><B>Results</B></P><P>Sixty-three patients were enrolled, and 59 received BR. The median age was 67 years (range, 36 to 75 years), and 62.7% of patients were 65 years of age or older. Fifty-seven patients (96.6%) were previously treated with rituximab-containing chemotherapy. The ORR was 62.7% (95% CI, 49.1% to 75.0%), with a CR rate of 37.3% (95% CI, 25.0% to 50.9%). The ORRs were comparable between patients ≥ 65 years of age and less than 65 years (62.2% and 63.6%, respectively). The median PFS was 6.7 months (95% CI, 3.6 to 13.7 months). The most frequently observed grade 3 or 4 adverse events were hematologic: lymphopenia (78.0%), neutropenia (76.3%), leukopenia (72.9%), CD4 lymphopenia (66.1%), and thrombocytopenia (22.0%).</P><P><B>Conclusion</B></P><P>BR is a promising salvage regimen for patients with relapsed or refractory DLBCL after rituximab-containing chemotherapy, warranting further investigation.</P>
Significance of rescue hybrid endoscopic submucosal dissection in difficult colorectal cases
Hayato Yamaguchi,Masakatsu Fukuzawa,Takashi Kawai,Takahiro Muramatsu,Taisuke Matsumoto,Kumiko Uchida,Yohei Koyama,Akira Madarame,Takashi Morise,Shin Kono,Sakiko Naito,Naoyoshi Nagata,Mitsushige Sugimo 대한소화기내시경학회 2023 Clinical Endoscopy Vol.56 No.6
Background/Aims: Hybrid endoscopic submucosal dissection (ESD), in which an incision is made around a lesion and snaring is per-formed after submucosal dissection, has some advantages in colorectal surgery, including shorter procedure time and preventing per-foration. However, its value for rescue resection in difficult colorectal ESD cases remains unclear. This study evaluated the utility of res-cue hybrid ESD (RH-ESD). Methods: We divided 364 colorectal ESD procedures into the conventional ESD group (C-ESD, n=260), scheduled hybrid ESD group(SH-ESD, n=69), and RH-ESD group (n=35) and compared their clinical outcomes. Results: Resection time was significantly shorter in the following order: RH-ESD (149 [90–197] minutes) >C-ESD (90 [60–140] min-utes) >SH-ESD (52 [29–80] minutes). The en bloc resection rate increased significantly in the following order: RH-ESD (48.6%), SH-ESD (78.3%), and C-ESD (97.7%). An analysis of factors related to piecemeal resection of RH-ESD revealed that the submucosal dis-section rate was significantly lower in the piecemeal resection group (25% [20%–30%]) than in the en bloc resection group (40% [20%–60%]). Conclusions: RH-ESD was ineffective in terms of curative resection because of the low en bloc resection rate, but was useful for avoid-ing surgery.
Shinji Hiyama,Toshie Sugiyama,Seiji Kusuhara,Takashi Uchida 대한수의학회 2012 JOURNAL OF VETERINARY SCIENCE Vol.13 No.3
The temporal expression of estrogen receptor (ER)α and ERβ mRNA was examined in male Japanese quails. Femurs of quails receiving 17βestradiol underwent RTPCR and histochemical analysis 1 to 15 days after treatment. Untreated quails were used as controls (day 0). Between days 0 and 5, cells lining the bone endosteal surface differentiated into osteoblasts, which in turn formed medullary bone. Expression of ERα was already observed on day 0 and increased slightly during bone formation whereas ERβ was hardly detected throughout this process. After osteoclasts appeared on the medullary bone surface, this type of bone disappeared from the bone marrow cavity (days 7∼15). ERα expression simultaneously decreased slightly and ERβ levels remained very low. These results suggest that estrogen activity mediated by ERα not only affects medullary bone formation but also bone resorption.