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      • 日本型水稻と日印交雜水稻における 分離種子根の伸長性の比較(I報)

        井之上 準,折谷 隆志,金晋鎬 順天大學校 1985 論文集 Vol.4 No.1

        日本型水稻20品種, 一印交雜水稻20品種の種子根·分離根を川田らの"改良培地"で培養し,分離根の發育を調査した. 1.分離根の長さは,27℃區では日本型水稻の10.9∼18.0㎝に대??して日印交雜水稻は13.2∼19.7㎝で,兩水稻品種間に著しぃ差異はなかったが,30℃區はでは9.1∼19.0㎝と16.7∼27.3㎝で,日本型水稻して日印交雜水稻の伸長は著しく良好であった. 2.分離根の乾物重は,27℃區ては日本型水稻が0.9∼2.0㎎でなったのに對し,日印交雜水稻は3.2∼5.7㎎, 30℃區では0.9∼2.3㎎に對し,4.2∼10.1㎎で,兩溫度흉にねい て兩品稻群間に明からな差が認られた.なね,この差異は30℃區にねいてより著しか った. 3.日本型水稻と日印交雜水稻の間にみられた分離根の乾物重の差異は,主に分지??根の發育の良否によるもので,特に長さ1∼5㎝の分岐根數に 差異が認られた. 4.上記のよらな分岐根の發育の違いは品種群の特性によるものか,あるいは"改良培地"に對する適應度が異なることによるものかについては不明であり,今後にまちたい. 謝辭:本實驗の遂行にあたり有益な助言をいただいた佐賀大學農學部田中典幸博土に深く 感謝いたします. Based on a culture method of excised root tip reported by Kawata et al.??, this study examined growth of seminal root tips of Japonica type and Japonica-Indica hybrid rices. Throughout the studies, the 1㎝ long root tips to initiate experiments were excised from seminal roots and the two root tips had grown in each flask containing 15ml of the culture solution. They had grown at 27 or 30℃ in the dark for three weeks, until the root growth ceased. Plant materials used were 20 varieties of Japonica-Indica hybrids bred in Korea, 10 varieties of Korean paddy rice and 10 ones of Japanese paddy rice. The following results were obtained. 1. Root length at 27℃ varied from 10.9 to 18.0㎝ in the Japonica type rice and from 13.2 to 19.7㎝ in the Japonica-Indica hybrid rice. At 30℃, it was from 9.1 to 19.0㎝ in the former and from 16.7 to 27.3㎝ in the latter. 2. In the both cultural temperatures of 27 and 30℃, Japonica-Indica hyvrid rice had more number of the well developed branched roots than the Japonica type rice. The dry root weight which seems to represent the root growth was from 0.9 to 2.0㎎ in the Japonica type rice and from 3.2 to 5.7㎎ in the Japonica-Indica hyvrid rice at 27℃, while it was from 0.9 to 2.3㎎ in the frmer and from 4.2 to 10.1㎎ in the latter at 30℃. 3. Excised root growth of the Japonica type rice was better at 27℃, than at 30℃, while in the case of the Japonica-Indica hybrid rice this was reverse.

      • The relationships between the arrangement of teeth, root resorption, and dental maturity in bovine mandibular incisors

        Jin-kyu An,Yoshiro Matsumoto,Takashi Ono 대한치과교정학회 2017 대한치과교정학회지 Vol.47 No.6

        Objective: The objective of this study is to investigate the eruption pattern and root resorption of the bovine anterior dentition in relation to growth-related parameters based on dental maturity. Methods: A cross-sectional study was conducted on 110 bovine anterior mandibles by using standard radiography, cone-beam computed tomography (CBCT), and actual measurements. We determined the relationships between the stages of dental maturity by using a modification of Demirjian’s method and various growth-related parameters, such as the activity of the root-resorbing tissue and mobility of the deciduous teeth. The correlation of growth-related parameters with interdental spacing and distal unusual root resorption (DRR) of the deciduous fourth incisor was assessed. The cause of mesial unusual root resorption (MRR) of the deciduous fourth incisor was determined on the basis of the arrangement of the permanent third incisor. Results: An independent t-test and chi-square test indicated significant differences in growth-related parameters associated with dental arch length discrepancy and factors related to the shedding of deciduous teeth between the low and high dental maturity groups. The samples with interdental spacing and DRR showed a larger sum of mesiodistal permanent crown widths and higher dental maturity than did the respective controls. Samples with MRR tended to show a lingually rotated distal tip of the adjacent tooth crown. Conclusions: Dental maturity has relevance to the interdental spaces and unusual root resorption of mixed dentition. The position of the adjacent tooth crown on CBCT may be correlated with the occurrence of unusual root resorption of the incisor.

      • SCOPUSKCI등재
      • SCISCIESCOPUS

        Imaging of pure spin-valley diffusion current in WS<sub>2</sub>-WSe<sub>2</sub> heterostructures

        Jin, Chenhao,Kim, Jonghwan,Utama, M. Iqbal Bakti,Regan, Emma C.,Kleemann, Hans,Cai, Hui,Shen, Yuxia,Shinner, Matthew James,Sengupta, Arjun,Watanabe, Kenji,Taniguchi, Takashi,Tongay, Sefaattin,Zettl, A American Association for the Advancement of Scienc 2018 Science Vol.360 No.6391

        <P>Transition metal dichalcogenide (TMDC) materials are promising for spintronic and valleytronic applications because valley-polarized excitations can be generated and manipulated with circularly polarized photons and the valley and spin degrees of freedom are locked by strong spin-orbital interactions. In this study we demonstrate efficient generation of a pure and locked spin-valley diffusion current in tungsten disulfide (WS2)-tungsten diselenide (WSe2) heterostructures without any driving electric field. We imaged the propagation of valley current in real time and space by pump-probe spectroscopy. The valley current in the heterostructures can live for more than 20 microseconds and propagate over 20 micrometers; both the lifetime and the diffusion length can be controlled through electrostatic gating. The high-efficiency and electric-field-free generation of a locked spin-valley current in TMDC heterostructures holds promise for applications in spin and valley devices.</P>

      • KCI등재

        Structural and Tunable Characteristics of Ba(ZrxTi1−x)O3 Films Prepared by RF-magnetron Sputtering Using a Metal Target

        Jin-Woong Kim,Hiromi Shima,Ken Nishida,Takashi Yamamoto,Hiroshi Funakubo 한국물리학회 2014 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.65 No.3

        Ba(ZrxTi1−x)O3 (BZT) thin films with different Zr contents were deposited on (100)MgO and(100)Pt/(100)MgO substrates by RF-magnetron sputtering using metal targets. The BZT thinfilms epitaxially grew on MgO substrates with only a (001)/(100) orientation and had a singleperovskite phase. In all cases, Ba/Ti ratio was stoichiometric and the BZT films possessed a densemicrostructure. The grain size decreased with increasing Zr content. At room temperature, adielectric constant as a function of the DC bais (tunability) of nearly 30% was achieved at 1 MHz;meanwhile, a relatively low dielectric loss was obtained. Moreover, after a post-annealing process,the tunability was increased significantly. These results indicate that we succeeded in depositinghigh-quality, and potential tunable ferroelectrics.

      • SCISCIESCOPUS

        Fluorescence emission and image patterning from selective photocyclic aromatization of cis–cisoid helical poly(phenylacetylene)s <i>in situ</i> in a film via top-down photodegradation

        Jin, Young-Jae,Park, Hyosang,Lee, Chang-Lyoul,Teraguchi, Masahiro,Kaneko, Takashi,Aoki, Toshiki,Kwak, Giseop Elsevier 2018 Dyes and pigments Vol.149 No.-

        <P><B>Abstract</B></P> <P>Selective photocyclic aromatization (SCAT) of cis–cisoid helical poly(phenylacetylene) derivatives was investigated during the <I>in situ</I> photodegradation in a film. An infrared absorption peak appeared at ∼1700 cm<SUP>−1</SUP> owing to the overtone vibration of the 1,3,5-trisubstituted benzene and the peak at 1060 cm<SUP>−1</SUP> due to the cis C=C bending of the main chain decreased, indicating occurrence of SCAT. Simultaneously, the polymer film became emissive in visible region during SCAT. The fluorescence (FL) quantum efficiency was approximately 0.92% in the film and not so much high relative to usual fluorophores. The FL emission disappeared in an instant when the decomposition product dissolved in a solvent. The FL lifetime of the polymer film increased with photodegradation. These all indicated the occurrence of excimer emission. A finely resolved FL image pattern was readily obtained using a photomask.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Selective photocyclic aromatization of cis–cisoid helical poly(phenylacetylene)s occurred during the photodegradation. </LI> <LI> The polymer films were converted to decomposition products of 1,3,5-trisubstituted benzene derivatives. </LI> <LI> At the same time, the polymer films turned emissive in visible region, while they were almost not emissive originally. </LI> <LI> When the decomposition products dissolved in a solvent, the fluorescence disappeared in an instant. </LI> <LI> A finely resolved fluorescence image pattern was obtained using an appropriate photomask. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

      • Long-term nintedanib treatment in idiopathic pulmonary fibrosis (IPF) : final data from INPULSIS-ON

        ( Jin Woo Song ),( Bruno Crestani ),( Manuel Quaresma ),( Mitchell Kaye ),( Takashi Ogura ),( Wibke Stansen ),( Susanne Stowasser ),( Michael Kreuter ) 대한결핵 및 호흡기학회 2018 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.126 No.-

        Background & Aims: The two 52-week Phase III INPULSIS trials investigated the efficacy and safety of nintedanib 150 mg bid vs placebo in patients with IPF. Patients who completed an INPULSIS trial could receive open-label nintedanib in the extension trial INPULSIS-ON. We assessed the long-term efficacy and safety of nintedanib based on final data from INPULSIS-ON. Methods: Placebo-treated patients in INPULSIS initiated nintedanib in INPULSIS-ON; patients treated with nintedanib in INPULSIS continued nintedanib in INPULSIS-ON. Results: 734 patients were treated in INPULSIS-ON (430 continuing nintedanib; 304 initiating nintedanib). Mean (SD) exposure in INPULSIS-ON was 29.0 (16.4) months; total exposure to nintedanib in both INPULSIS and INPULSIS-ON was 42.1 (16.0) months (max: 68.3 months). In INPULSIS, mean (SD) changes from baseline in FVC at week 52 were -89 (264) mL with nintedanib vs -203 (293) mL with placebo; annual rates (SE) of decline in FVC were -114 (11) mL/year and -224 (13) mL/year in these groups. In INPULSIS-ON, mean (SD) change from baseline in FVC at week 192 was -327 (385) mL; the annual rate (SE) of decline in FVC over 192 weeks was -135 (6) mL/year. The adverse event profile of nintedanib in INPULSIS-ON was consistent with that observed in INPULSIS. Conclusions: Final data from INPULSIS-ON indicate that the effect of nintedanib on reducing disease progression in patients with IPF is maintained over the long term. Nintedanib treatment, up to 68 months, had an acceptable safety and tolerability profile.

      • KCI등재

        Inhibition of plasminogen activator inhibitor-1 attenuates against intestinal fibrosis in mice

        ( Jin Imai ),( Takashi Yahata ),( Hitoshi Ichikawa ),( Abd Aziz Ibrahim ),( Masaki Yazawa ),( Hideaki Sumiyoshi ),( Yutaka Inagaki ),( Masashi Matsushima ),( Takayoshi Suzuki ),( Tetsuya Mine ),( Kiyo 대한장연구학회 2020 Intestinal Research Vol.18 No.2

        Background/Aims: Intestinal fibrosis is a major complication of Crohn’s disease (CD). The profibrotic protein transforming growth factor-β (TGF-β) has been considered to be critical for the induction of the fibrotic program. TGF-β has the ability to induce not only the expression of extracellular matrix (ECM) including collagen, but also the production of plasminogen activator inhibitor-1 (PAI-1) that prevents enzymatic degradation of the ECM during the onset of fibrotic diseases. However, the significance of PAI-1 in the developing intestinal fibrosis has not been fully understood. In the present study, we examined the actual expression of PAI-1 in fibrotic legion of intestinal inflammation and its correlation with the abnormal ECM deposition. Methods: Chronic intestinal inflammation was induced in BALB/c mice using 8 repeated intrarectal injections of 2,4,6-trinitrobenzene sulfonic acid (TNBS). TM5275, a PAI-1 inhibitor, was orally administered as a carboxymethyl cellulose suspension each day for 2 weeks after the sixth TNBS injection. Results: Using a publicly available dataset (accession number, GSE75214) and TNBS-treated mice, we observed increases in PAI-1 transcripts at active fibrotic lesions in both patients with CD and mice with chronic intestinal inflammation. Oral administration of TM5275 immediately after the onset of intestinal fibrosis upregulated MMP-9 (matrix metalloproteinase 9) and decreased collagen accumulation, resulting in attenuation of the fibrogenesis in TNBS-treated mice. Conclusions: PAI-1-mediated fibrinolytic system facilitates collagen degradation suppression. Hence, PAI-1 inhibitor could be applied as an anti-fibrotic drug in CD treatment. (Intest Res 2020;18:219-228)

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