참지식 부직포여과 활성슬러지 시스템의 가정 오수처리 적용 타당성 조사 연구

임태진,서규태,이택순,문병현 7개 국립대학교 환경연구 논문집 공동발행 위원회 2002 환경연구논문집 Vol.2 No.1

An experimental study was conducted to investigate the applicability of non-woven fabric filter as an alternative separation material in membrane combined activated sludge process. The most advantage of the fabric filtration activated sludge system is the low operation and maintenance cost resulting from the ready available material and gravity filteration. The system was consisted of two reactors, anoxic and aerobic one with working volume of 0.28㎥ and 0.47㎥, respectively. The non-woven fabric filter module was immersed in the aerobic compartment for separation of activated sludge by gravity filtration. Although the system showed high potential to treat domestic wastewater the initial leakage of bio-solid from the reactor and reduction of permeate flux were main problems of the system. The initial flux of 0.4㎥/㎡/day reduced to 0.2㎥/㎡/day in 12 days operation at 133㎝ water head. During the stable operation period, average SS concentration of effluent was 1.8㎎/L showing 96.4% removal. Organic removal efficiency was 98.3% as COD_Cr and 91.6% as BOD with the effluent concentration, 14.4㎎/L and 1.5㎎/L, respectively. T-N removal efficiency was 60% at C/N ratio 4.5.

분말야금법에 의해 제조된 소결 GEAR 및 RATCHET의 조직 특성

임태환,이창순,박인규 선문대학교 중소기업기술지원연구소 1997 선문공대 연구/기술 논문집 Vol.2 No.1

활성탄에서 할로카본의 흡착 평형

장원철,임진규,이태진 嶺南大學校 環境問題硏究所 1994 環境硏究 Vol.13 No.2

두가지 활성탄에 대한 4가지 할로카본(CFC-113, CFC-11, Methylene Chloride, 1,1,1-TCE)의 흡착평형을 용량법으로 473K의 진공에서 밤새 처리한 후에 298-473K에서 측정하였다. Clausius-Clapeyron식으로 구해진 흡착열은 Henry's law constants로 구한 흡착열과 같은 크기의 정도(order of magnitude)를 보였으며 표면점유율에 상관없이 거의 일정하였다. 실험측정치를 BET상관식, Langmuir식, Dubinin-Astakhov식으로 해석하였으며 흡착제의 변수를 결정하였다. Dubinin-Astakhov식의 지수 n은 1.2∼2.7의 범위를 보였으며 이 값들은 흡착질과 흡착제간의 상호 작용의 의존도를 보여주었다. 흡착특성에너지 E와 지수 n은 흡착질의 분자직경 d에 의해 상관 관계를 맺을 수 있었다. Adsorption equilibria of four kinds of Halocarbons(CFC-113, CFC-11, Methylene Chloride, 1,1,1-TCE) on two activated carbons were measured at 298-473 K by using a static adsorption apparatus. The adsorbents were regenerated overnight at 473K under vacuum condition. The heat of adsorption calculated from Clausius-Clapeyron equation and that obtained from Henry's law constants showed the same order of magnitude. And it remained nearly constant irrespective of the surface coverage. Experimental data were correlated by BET, Langmuir, and Dubinin-Astakhov equations with the parameters of the adsorbents. The exponent n in Dubinin-Astakhov equation ranged from 1.2 to 2.7 depending on the adsorbate-adsorbent system. The characteristic energy of adsorption E and the exponent n were correlated by the molecular diameter d of the adsorbate.

자궁경부 상피내 병변 환자에서 LEETZ 원추절제술 후 HPV DNA Test 추적 검사의 임상적 의의

김미향,이태화,오영림,이천준,김원규 고신대학교 의과대학 2009 고신대학교 의과대학 학술지 Vol.24 No.2

Objective: This study was performed to investigate the clinical significance and timing of HPV test for follow up of patients after LEETZ treatment in CIN lesion Methods: From January 2005 to December 2008, 105 patients with CIN were treated with LLETZ at Kosin university gospel hospital, Busan, Korea. After LEETZ, HPV test and Pap smear were done after 3months. Every HPV typing was done by HPV DNA chip. Results: A total of 105 cases were enrolled in this study. There were 25 patients with CINⅠ, 38 with CINⅡ, 42 with CINⅢ. Mean age was 41.95 years (range, 23-71 years) at the time of LEETZ. Positive HPV DNA was found about 72.4% before LEETZ procedure and subtype 16 was the most common type (10.5%), follow by subtype 18 (6.6%) and subtype 58 (6.6%). During follow up after LEETZ, 65.6% had negative result after 3 month, 72.1% after 6 month, 73.9% after 9 month, 77.1% after 12 month, 79.2% after 15 month, 79.6% after 18 month, and 80.4% after 24 month. There were 2 cases of abnormal pap smear among persistent positive HPV DNA cases and no abnormal pap smear results in negative HPV DNA cases during follow up. Conclusion: Positive HPV DNA was found about 72.4% before LEETZ procedure and subtype 16 was the most common type (10.5%), follow by subtype 18 (6.6%) and subtype 58 (6.6%). We suggest that HPV DNA test is recommended per 6 Months, and close observation is recommended in persistent positive HPV DNA test cases.

열처리 개선을 통한 전동 공구 Gear류의 수명 향상에 관한 연구

이창순,임태환,박인규 선문대학교 중소기업기술지원연구소 1997 선문공대 연구/기술 논문집 Vol.2 No.1

2차원 Laplace 변환 경계요소법에 의한 이종재료의 충격해석

조상봉,김태규,임호성 慶南大學校 附設 工業技術硏究所 1993 硏究論文集 Vol.11 No.-

이종재료의 충격문제를 해석하기 위하여 기존의 단일영역 2차원 Laplace 변환 경계요소법 프로그램에 접합경계에서 완전결합조건을 이용한 다중영역 결합법을 부가하여 이종재료의 동적문제가 해석가능하도록 프로그램을 작성하였다. 등방성 재료에 대한 정적 및 동적문제에서 단일영역에 의한 해석 결과와 영역결합법에 의한 해석 결과가 잘 일치함을 확인하였다. 이종재료의 해석에 2차원 Laplace 변환 경계요소법 프로그램을 응용하여 몇가지 모델을 해석하였고, 해석결과를 물리적인 측면에서 타당성을 분석하여 이종재료의 충격해석이 가능함을 확인하였다. For BEM analyses of the impact problems of dissimilar materials, the method of connected multi-regions using perfect bonded conditions on the interface boundaries was implemented to the two-dimensional Laplace transformed-domain BEM program for a single-region and multi-regions for a homogeneous isotropic material are consistent well. The two-dimensional Laplace transformed-domain BEM program with the method of connected multi-regions was applied to analyse several impact problems of dissimilar materials and it was confirmed the possibility of BEM impact analyses for dissimilar materials by the analysis of the BEM results for impact problems of dissimilar materials on physical grounds.

GIS를 이용한 산불발생위험지역 구분

이시영,안상현,원명수,이명보,임태규,신영철 한국지리정보학회 2004 한국지리정보학회지 Vol.7 No.2

산불로 인한 재해를 미연에 방지하고 피해를 저감하기 위해서는 산불발생위험지역을 사전에 파악하여 예방대책을 세울 필요가 있다. 따라서 본 연구에서는 산불발생인자에 따른 산불발생위험지역을 구분하고자 겸상북도 의성군에서 발생한 산불피해지역에 대하여 임상, 지형 등에 대하여 조사하였다. 조사된 요인들 간 독립성 유무를 상관분석을 이용하여 산불발생과 관련 있는 7개의 주제도를 선정하였으며, 선정된 주제도를 조건부확률과 지리정보시스템을 이용하여 산불발생확률을 계산하였다. 계산된 산불발생확률을 20개 등급으로 지수화하여 산불발생위험지역을 구분하였다. In order to decrease the area damaged by forest fires and to prevent the occurrence of forest fires, we are making an effort to improve prevention measures for forest fires. The objective of this study is to classify hazard regions where forest fires occur based on the factors that contribute to the occurrence of forest fires. Forest fire sites in the Uiseong-gun, Gyeongsangbuk-do were surveyed according to the factors of forest type and topographic characteristics where the forest fires occurred. We used a correlation analysis to determine the forest fire occurrence factors and a conditional probability analysis and GIS to determine a forest fire danger index. The resulting forest fire danger index was used in the classification of forest fire occurrence risk regions.

동종 골수이식 후 만성 이식편대숙주질환과 동반되어 신증후군으로 발현된 IgA 신병증 1예

정철권,김현수,박준성,정성현,조도연,최진혁,남동기,임호영,김명성,신규태,임현이,김효철 대한조혈모세포이식학회 1999 대한조혈모세포이식학회지 Vol.4 No.2

동종 골수이식 후 발생하는 신기능부전은 원인이 다양하여 감별에 어려움이 있다. 만성 GVHD는 흉선의 기능저하에 따른 면역관용의 실패로 발생되는 자가면역현상에 의해 발생되는 것으로 알려져 있으며 드물게 신장을 침범하여 신증후군을 일으키기도 한다. CaA의 용량을 줄이거나 투약중지 후 발생한 만성 GVHD에 동반된 신증후군의 경우 조기에 신조직검사를 시행하여 감별진단하고 CsA의 용량을 증량하거나 재투약하여 좋은 치료 결과를 보일 것으로 기대된다. 저자들은 문헌고찰을 통해 동종 골수이식 후 발생된 신증후군이 유사한 임상양상을 보이며 발생기전에 만성 GVHD와 자가면역현상이 연관되어 있음을 확인하였으며 동종 골수이식 후 신증후군의 임상양상을 보이는 환자에서 병리조직학적으로 lgA 신병증을 진단하고 이러한 lgA 신병증이 발생기전에 만성 GVHD와 자가 면역현상이 연관되어 있을 가능성을 최초로 확인하였으며 CsA를 이용하여 성공적으로 치료한 경험을 하였기에 보고하는 바이다. Renal insufficiency is occasionally encountered in allogeneic bone marrow transplantation and its cause is difficult to ascertain. Chronic graft-versus-host disease (GVHD) related to thymic dysfunction is immune-mediated and involves autoreactivity of T-lymphocytes derived from donor marrow to recipient's major histocompatibility complex(MHC) minor antigens. The clinical mainifestations of chronic GVHD are similar to those of autoimmune disease but kidney involvement is rare. Few cases of nephrotic syndrome with membranous nephropathy or minimal change nephrotic syndrome have been reported to be associated with chronic GVHD in allogeneic bone marrow transplant recipient especially after cyclosporine A(CsA) withdrawal, and these cases have responded well to CsA. Therefore, it is prudent to differentiate the cause of post-transplant renal insufficiency using renal biopsy and to start CsA in a case of nephrotic syndrome associated with chronic GVHD as early as possible. We report a case who had a massive proteinuria during the post-allogeneic marrow transplantation period. The cause of nephrotic syndrome was diagnosed as IgA nephropathy by renal biopsy. The patient was successfully treated with reintroduction of CsA.

Curcumin Suppresses Proliferation of Colon Cancer Cells by Targeting CDK2

Lim, Tae-Gyu,Lee, Sung-Young,Huang, Zunnan,Lim, Do Young,Chen, Hanyong,Jung, Sung Keun,Bode, Ann M.,Lee, Ki Won,Dong, Zigang American Association for Cancer Research 2014 CANCER PREVENTION RESEARCH Vol.7 No.4

<P>Curcumin, the yellow pigment of turmeric found in Southeast Indian food, is one of the most popular phytochemicals for cancer prevention. Numerous reports have demonstrated modulation of multiple cellular signaling pathways by curcumin and its molecular targets in various cancer cell lines. To identify a new molecular target of curcumin, we used shape screening and reverse docking to screen the Protein Data Bank against curcumin. Cyclin-dependent kinase 2 (CDK2), a major cell-cycle protein, was identified as a potential molecular target of curcumin. Indeed, <I>in vitro</I> and <I>ex vivo</I> kinase assay data revealed a dramatic suppressive effect of curcumin on CDK2 kinase activity. Furthermore, curcumin induced G<SUB>1</SUB> cell-cycle arrest, which is regulated by CDK2 in HCT116 cells. Although the expression levels of CDK2 and its regulatory subunit, cyclin E, were not changed, the phosphorylation of retinoblastoma (Rb), a well-known CDK2 substrate, was reduced by curcumin. Because curcumin induced cell-cycle arrest, we investigated the antiproliferative effect of curcumin on HCT116 colon cancer cells. In this experiment, curcumin suppressed HCT116 cell proliferation effectively. To determine whether CDK2 is a direct target of curcumin, CDK2 expression was knocked down in HCT116 cells. As expected, HCT116 sh-CDK2 cells exhibited G<SUB>1</SUB> arrest and reduced proliferation. Because of the low levels of CDK2 in HCT116 sh-CDK2 cells, the effects of curcumin on G<SUB>1</SUB> arrest and cell proliferation were not substantially relative to HCT116 sh-control cells. From these results, we identified CDK2 as a direct target of curcumin in colon cancer cells. <I>Cancer Prev Res; 7(4); 466–74. ©2014 AACR</I>.</P>

Analysis of Airflow Pattern in Plant Factory with Different Inlet and Outlet Locations using Computational Fluid Dynamics

( Tae Gyu Lim ),( Yong Hyeon Kim ) 한국농업기계학회 2014 바이오시스템공학 Vol.39 No.4

Purpose: This study was conducted to analyze the air flow characteristics in a plant factory with different inlet and outlet locations using computational fluid dynamics (CFD). Methods: In this study, the flow was assumed to be a steady-state, incompressible, and three-dimensional turbulent flow. A realizable k- ε turbulent model was applied to show more reasonable results than the standard model. A CFD software was used to perform the numerical simulation. For validation of the simulation model, a prototype plant factory (5,900 mmⅹ2,800 mmⅹ2,400 mm) was constructed with two inlets (Φ250 mm) and one outlet (710 mmⅹ290 mm), located on the top side wall. For the simulation model, the average air current speed at the inlet was 5.11 m?s-1. Five cases were simulated to predict the airflow pattern in the plant factory with different inlet and outlet locations. Results: The root mean square error of measured and simulated air current speeds was 13%. The error was attributed to the assumptions applied to mathematical modelling and to the magnitude of the air current speed measured at the inlet. However, the measured and predicted airflow distributions of the plant factory exhibited similar patterns. When the inlets were located at the center of the side wall, the average air current speed in the plant factory was increased but the spatial uniformity was lowered. In contrast, if the inlets were located on the ceiling, the average air current speed was lowered but the uniformity was improved. Conclusions: Based on the results of this study, it was concluded that the airflow pattern in the plant factory with multilayer cultivation shelves was greatly affected by the locations of the inlet and the outlet.