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      • KCI등재

        Local Condensation Heat Transfer Characteristics of Refrigerant R1234ze(E) Flow Inside a Plate Heat Exchanger

        Mohammad Sultan Mahmud,Keishi Kariya,AKIO MIYARA 대한설비공학회 2017 International Journal Of Air-Conditioning and Refr Vol.25 No.1

        In the present study, local condensation heat transfer coefficients of the R1234ze(E) inside a vertical plate heat exchanger (PHE) were investigated experimentally. In the experiment, three vertical flow channels are formed in the test section where refrigerant flows downward in the middle channel and cooling water flows upward in other two channels. The test section consists of eight plates: two of them form a channel of chevron type PHE for refrigerant flow channel, other two flat plates are set for heat transfer measurements, and another consist on cooling water flow channel. Down flow of the condensing refrigerant R1234ze(E) in the center channel releases heat to other channels of cooling water. In order to measure local heat transfer characteristics, a total of 60 thermocouples were set at middle of flow direction and also in the right and left sides of plates in test section. Experiments were conducted for mass fluxes ranging from 10kg/m2s to 50kg/m2s. The measurement results show that local heat transfer coefficients decrease with increase of wetness with different values in horizontal direction. Further, characteristics of local heat flux and wall temperature distribution as a function of distance from inlet to outlet of refrigerant channel were explored in detail.

      • KCI등재

        Functional Prediction of Hypothetical Proteins from Shigella flexneri and Validation of the Predicted Models by Using ROC Curve Analysis

        Md. Amran Gazi,Sultan Mahmud,Shah Mohammad Fahim,Mohammad Golam Kibria,Parag Palit,Md. Rezaul Islam,Humaira Rashid,Subhasish Das,Mustafa Mahfuz,Tahmeed Ahmeed 한국유전체학회 2018 Genomics & informatics Vol.16 No.4

        Shigella spp. constitutes some of the key pathogens responsible for the global burden of diarrhoeal disease. With over 164 million reported cases per annum, shigellosis accounts for 1.1 million deaths each year. Majority of these cases occur among the children of the developing nations and the emergence of multi-drug resistance Shigella strains in clinical isolates demands the development of better/new drugs against this pathogen. The genome of Shigella flexneri was extensively analyzed and found 4,362 proteins among which the functions of 674 proteins, termed as hypothetical proteins (HPs) had not been previously elucidated. Amino acid sequences of all these 674 HPs were studied and the functions of a total of 39 HPs have been assigned with high level of confidence. Here we have utilized a combination of the latest versions of databases to assign the precise function of HPs for which no experimental information is available. These HPs were found to belong to various classes of proteins such as enzymes, binding proteins, signal transducers, lipoprotein, transporters, virulence and other proteins. Evaluation of the performance of the various computational tools conducted using receiver operating characteristic curve analysis and a resoundingly high average accuracy of 93.6% were obtained. Our comprehensive analysis will help to gain greater understanding for the development of many novel potential therapeutic interventions to defeat Shigella infection.

      • KCI등재후보

        Functional Prediction of Hypothetical Proteins from Shigella flexneri and Validation of the Predicted Models by Using ROC Curve Analysis

        Gazi, Md. Amran,Mahmud, Sultan,Fahim, Shah Mohammad,Kibria, Mohammad Golam,Palit, Parag,Islam, Md. Rezaul,Rashid, Humaira,Das, Subhasish,Mahfuz, Mustafa,Ahmeed, Tahmeed Korea Genome Organization 2018 Genomics & informatics Vol.16 No.4

        Shigella spp. constitutes some of the key pathogens responsible for the global burden of diarrhoeal disease. With over 164 million reported cases per annum, shigellosis accounts for 1.1 million deaths each year. Majority of these cases occur among the children of the developing nations and the emergence of multi-drug resistance Shigella strains in clinical isolates demands the development of better/new drugs against this pathogen. The genome of Shigella flexneri was extensively analyzed and found 4,362 proteins among which the functions of 674 proteins, termed as hypothetical proteins (HPs) had not been previously elucidated. Amino acid sequences of all these 674 HPs were studied and the functions of a total of 39 HPs have been assigned with high level of confidence. Here we have utilized a combination of the latest versions of databases to assign the precise function of HPs for which no experimental information is available. These HPs were found to belong to various classes of proteins such as enzymes, binding proteins, signal transducers, lipoprotein, transporters, virulence and other proteins. Evaluation of the performance of the various computational tools conducted using receiver operating characteristic curve analysis and a resoundingly high average accuracy of 93.6% were obtained. Our comprehensive analysis will help to gain greater understanding for the development of many novel potential therapeutic interventions to defeat Shigella infection.

      • KCI등재

        Dilution of the Magnetic Moment of Fe by Cr for Fe73.5-xCrxCu1Nb3Si13.5B9 and the Field-Cooled and Zero-Field-Cooled Behavior for Higher Cr Content

        S. S. Sikder,M. A. Hakim,S. Manjura Hoque,Md. Sultan Mahmud,P. Nordblad 한국물리학회 2008 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.53 No.2

        The temperature and the field dependences of the magnetization have been measured for Fe73:5-xCrxCu1Nb3Si13:5B9 (0 ≤ x ≤ 17.5) prepared by using a melt spin technique. The temperature dependence of the magnetization in the range of 5 to 300 K with an applied field of 1 Tesla for all the compositions follows the relaxation M(T) = M0(1-BT3/2 -CT5/2), which is indicative of the presence of a spin wave excitation. The saturation magnetizations at 5 and 300 K decrease linearly with Cr concentration for the entire composition range, which indicates that a simple dilution of the Fe moment takes place due to Cr substitution. The field-cooled (FC) and the zero-field-cooled (ZFC)magnetizations measured with an applied field of 1 Oe show divergences for x = 10, 12.5, 15 and 17.5, which may be attributed to the magnetic hardening at low temperatures.

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