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      • SCOPUSKCI등재

        이온성 혈관조영제 Talabrix가 동맥혈관내막과 미세혈관 문합 후 혈관개폐에 미치는 영향

        홍순원,김용욱,탁관철,박병윤 大韓成形外科學會 1993 Archives of Plastic Surgery Vol.20 No.1

        In the free flap surgery using microvascular anastomosis, angioraphy is widely used as an integral part of preoperative plans. The necessity of angiography is well extablished. But since there exist many controversies regarding adverse effects of angiography. especially there is no concrete evidence about their effects on the patency after microvascular anastomosis, This study attempts to examine the chronological changes of the arterial intima after systemic injection of ionic contrast media sodium iothamate(Talabrix ) and to evaluate its effects on the patency of microvascular anastomosis. Fifty-nine Sprague Dawley rats were divided into 5 groups according to time interval between contrast media injection and microvascular anastomosis. The time intervals were 1 day, 3 days, 7 days, and 14 days after contrast media injection. The ionic contrast media was injected intraveneously through the tail vein. Left inguinal arteries were anastomosed under an operating microscope after the contrast media injection. After the above procedures and reviewing all the results, we can conclude that ionic angiographic dye causes reversible injuries to the vascular intima, and deteriorates patency of the microvascular anastomosis. And we suggest that a time interval more than at least 7 days to 14 days, between anguographic study and flap transfer is requested.

      • 우리 나라 自然洞窟의 現況과 利用에 關한 硏究

        洪始煥,朴寬燮,任文淳,全順任 건국대학교 1978 學術誌 Vol.22 No.1

        Our country has many limestone caves. There are about two hundred and thirty caves all over the country. Among them ninth percentages are limestone caves. We divide them into four classes as the limestone cove, lava cave erosion cave. We dlassify them with the component of formation for example, the limestone cave in the Karst region, the erosion cave in the seaside and the lava cave around the volcanic zone in Jeaioo Island. With geographical distribution, we could discover the limestone eave generally around the Gangwon Province, the Gyungsang Province the Chungcheung Province and the lava cave in Jea boo Province. The erosion caves are developed along the coast. With the geological period, we could discover the limestone cave mainly in the Cambro-Oldovisian Stage. We can see the anvient creature in the cave, not discovered at the surface, because the living things in the cave were late for the development. And the direction of the cave has connection with geological features. Mainly it agree with a fault plane. Generally Caves maintain the temperature from 14 degrees to 17 degrees. Thus, the fried temperature is a character of the cave. From old time, cave is made use for the place of the residence. Academic study for the cave began in earnest at the late 19th century. Comparaticely spealcing, we started studying only ten years ago. We used only cave for the place of refuse. And the cave is used for storehouse or the place in order to train the mind. Now we had to study to utilize the cave in our new period. For the temperature of the cave is fixed, we can use the cave for store. Now we had to study to utilize the cave in our new period. For the temperature of the cave is fixed, we can use the cave for storehouse of the crops or of the military goods. It is important for the cave to use for the military strategy. And it is possible to captivate the mushroom in the cave. Besides, we can use the pond of the cave for fish-breeding, as Japan is utilizing the cave for a fry-breeding. It is vary important to investigate the size or form of our many caves so as to serve the national safety.

      • Developmental characterization of embryo size mutant in rice (Oryza sativa L.)

        Hong,Soon-Kwan 한국자원식물학회 2002 Plant Resources Vol.5 No.2

        In this experiment, three kinds of mutations(ge, re, and eml )relating to the size of embryos were used to study their generation, genetic mechanism and developmental characteristics, and the interactions between embryo and endosperm were also examined. Giant embryo mutation comprises 7 kinds including the already isolated ge, and ge-2, which share an identical gene site. The SAM and the size of radicule for the ge showed little difference compared to a normal type. The number of embryo cells did not increased as much as it would affect the size of embryo. Therefore, the enlargement of embryo was due to the enlargement of scutellum that originated from the corpulence of each cell. Both F$_1$ 수식 이미지 s of re ]and odm 49 formed reduce embryos, and other combinations of hybridization showed all wild type of embryo sizes. Accordingly, the odm 49 must have an identical gene site of re 1, while odm 48 and odm 62 have different gene sites. Their shoots and radicules also shrank by the same ratio, however no sign of physical change was noticed. The size of embryo cell showed no change, while the number of cells was the half of that of wild types. The three gene sites of re represent all of them control the size of the entire embryo forming organs. The eml 1 was defined to have temperature sensibilities that the generation of endosperms was active at a high temperature while that was hampered at a low temperature.

      • E. coli 과량발현을 통한 B형 간염 바이러스 preS1 유도체의 안정한 동위원소 N의 치환

        박병관,김세하,한규훈,김선영,홍요정,이시형,한동설,김순종,박진구 木浦大學校基礎科學硏究所 1997 基礎科學硏究誌 Vol.15 No.-

        We have used molecular biology technique to label the side chains and backbone of HBV preS1(1-56) with stable isotope (??) during E. coli over-expression and purified the protein to near homogeneity. The expression level of ?? labelled preS1(1-56) seems to be ∼15% of the total protein. to characterize the secondary structure of the labelled protein, circular dichroism was used. In different buffer conditions including pH 3.3 and pH 7.4 the protein seems to be devoid of any stable secondary structure probably suggesting that the N-terminal portion (preS1(1-56)) of HBV preS1 might be unstructured before binding to its target cells.

      • 붕소확산에 의한 산화적층결함의 후면게터링

        朴善宇,洪淳寬,金鐵柱 서울市立大學校 1991 論文集 Vol.25 No.-

        The backside gettering phenomena of OSFs which are generated at the Si-SiO₂interface during the oxidation is observed. After the backside boron diffusion at 1200℃ for 120min, the OSFs' density on the Si(100) front surface is reduced from 10?cm-²to about 20cm-²or below. In addition to, the rate of decrease of the OSFs' density is deduced experimentally as a function of the boron diffusion time and temperature.

      • 비안와대뇌형 모균증 치험 3례

        문영일,김종남,홍순관,이지애,정옥경,김문정 梨花女子大學校 醫科大學 醫科學硏究所 1997 EMJ (Ewha medical journal) Vol.20 No.3

        Rhinocerebral mucormycosis is a well-described fulminant fungal infection that typically presents in a rapidly fulminant manner. This condition is more likely to occur among patient with diabetes mellitus, malignant tumors, who have long-term steroid treatment, or who suffer from some debilitating diseases. We report 3 cases of rhinoorbitocerebral mucormycosis, all suffered from diabetes mellitus. In all 3 cases, endoscopic sinus surgery was done and the antifungal agent(amphotericin B) was administered intravenously, and two patients died. One survivor who had focal extension of paranasal sinus and orbit, required one surgical intervention without orbital exenteration and he is alive without recurrence disease. The severity of the disease is probably dependent upon the gost resistance to the invasion of phycomycetes. Early diagnosis and immediate, effective treatment are the key for cure of the disease.

      • 축우 부루셀라병의 ELISA 진단법에 관한 연구

        임윤규,이두식,박전홍,양기천,김승호,김공식,현관종,김우택,이영순 濟州大學校 農科大學 動物科學硏究所 1993 動物科學論叢 Vol.8 No.1

        Enzyme-linked Immuno sorbent Assay (ELISA) for the serological diagnosis oi Bruceiia abortus was developed and compared with plate aggluhnation test Cell wall antigen was extracted from Brucella abortus 1119-3 by sonicabon and with a sodium deoxychlate solution Optimum protein concentra tion of coating antigen 0.4㎍/100㎕ protein on each microtiter plate well. Horse radish peroxidase(HRP) labled protein-G was used as a tracer of reacted antibodies ELISA confirmed the agreeable results of 40 rases out of 43 cases by plate aggulutination test ELISA diagnosed positive cases (10 out of 12) and negatiw cases (1 out of 12) with dubious sera by plate agglutination test From this results EL ISA could be used for the early diagnostic tools of Brucellosis in cattle.

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