당뇨병과 동반된 화농성 간농양의 임상상 및 예후인자

오은숙,강무일,이원영,오기원,임동준,이소영,이정민,고승현,김성래,안유배,손현식,윤건호,차봉연,이광우,손호영,강성구 대한당뇨병학회 2000 임상당뇨병 Vol.1 No.1

연구배경: 감염질환은 혈관질환과 함께 당뇨병의 중요한 사망원인의 하나이며, 혈당조절이 불량할수록 감염 빈도가 증가됨은 잘 알려져 있다. 간농양의 발생이 있어서도 당뇨병은 중요한 기저질환 중의 하나이다. 일반적으로 간농양의 가장 흔한 원인균은 Escherichi coli라고 알려져 있으나, 최근 당뇨병을 가진 간농양 환자에서 Klesiella pneumoniae의 검출이 증가되고 있다. 또 최근 연구에 의하면 K.pneumonie가 간농양의 가장 흔한 원인균이며, K. pneumoniae에 의한 간농양은 K.pneumoniae 이외의 균주에 의한 간농양보다 당뇨병과 밀접히 관련되어 있다고 보고된 바 있다. 이에 저자들은 간농양 환자를 대상으로 당뇨병환자의 빈도를 알아보고, 그 원인균 및 특징을 비당뇨병 환자들의 경우와 비교해 보고자 하였다. 방법: 1992년 1월부터 1999년 6월까지 방사선학적 검사 혹은 수술에 의해 간농양이 확인되거나, 경피적 천자나 수술을 통한 배농액 배양, 혹은 혈액 검사에서 원인균이 증명된 182명의 환자를 대상으로 후향적 임상고찰을 실시하였다. 결과: 화농성 농양을 가진 167명의 환자(남:94명, 여:73명)중 당뇨병을 가진 환자는 54명 (남:30명, 여:24명)으로 32.3%를 차지하였다. 환자의 평균나이는 당뇨군에서 62.1 ± 13.4세, 비당뇨군에서는 55.1 ±15.5세로 당뇨군에서 높았으며(p=0.0021), 남녀간의 평균나이 비교 시 두 군 모두 여성의 나이가 의미있게 높았다. 비당뇨군에 비하여 당뇨군의 경우 저알부민혈증의 빈도와 aspartate transaminase가 증가되어있었다. 원인균주는 K. pneumoniae (당뇨군54%, 비당뇨군 39.1%), E. coli(당뇨군 17.5%, 비당뇨군 18.8%), Pseudomonas aeruginosa, Streptococcus viridans, Enterococcus 순이었으며 두 군간의 의미는 차이는 없었으나 K. pneumoniae의 경우 다른 균종에 비해 단독감염의 빈도가 높았다(82.8%). 사망률은 당뇨군에서 16.7%, 비당뇨군에서 7.1%로 당뇨군에서 의미있게 높았으며(p=0.019), 당뇨군에서의 사망환자는 모두 패혈증이 동반되어 있었다. 당뇨환자의 사망군은 생존군에 비해 당뇨병 이환기간이 길고 혼합감염의 빈도가 높았다(p=0.046). 검사실 소견에서는 총 빌리루빈 및 알카리성 포스파타제의 증가가 관찰되어 있었다. 결론: E. coli가 간농양의 주된 원인균이라는 기존 보고와는 달리 당뇨군과 비당뇨군 모두 K. pneumoniae가 간농양의 주된 원인균이었다. 또한 당뇨 유병기간이 길고 당뇨조절이 불량한 환자에서 혼합감염이며 총 빌리루빈 및 알카리성 포스파타제의 증가등과 같은 위험인자가 존재할 경우 사망률이 증가될 수 있으므로 이들 군에서는 적극적인 치료가 필요할 것으로 사료된다. Background: Liver abscesses are commonly associated with underlying disease, particularly diabete mellitus. The number of the liver abscesses caused by Klebslella pneumoniae in diabetic patient has been increased in Korea nowadays. This study was conducted to clarify the clinical presentation and prognostic factors of pyogenic liver abscesses, especially in diabetic patients and to determine the proportion of K. pneunomiae as a pathogen in liver abscess in Korea. Methods: Medical records of 167 patients treated for pyogenic liver abscess from January, 1992 through June, 1999 were reviewed retrospectively in detail. Major Pathogenic organism, clinical manifestations, prognostic factors, the importance of diabetes mellilus as an underlying disease and its effect on clinical features and prognosis were analyzed. Results: Among 167 cases of pyogenic liver abscess, underlying diabetes mellitus was present in 32.3%. The mean age of patients was 62.7 13.4 years in diabetic liver abscess group and 55.1 15.5 years in non-diabetic liver abscess group. Most liver abscesses were cryptogenic in origin or secondary to the billary tree diseases. The clinical presentations among the two groups were not significantly different. When compared to patients without diabetes, patients with diabetes had significantly higher proportions of hypoalbuminemia and elevated aspartate transaminase level. The most common organism of the pyogenic abscess was K. pneumoniae in both groups. Percutaneous drainage of the abscess with appropriate antibiotics was the most commonly used therapeutic modality in liver abscess. The mortality rate of diabetic liver abscess is 16.1 % and 7.1% in nondiabetic liver abscess. Complications, especially septicemla, were found more frequently in patients with diabetes than in patients without diabetes (64.8% vs 28.3%, septicemia : 31.5% vs 9.7%). The factors influencing mortality in the diabetic liver abscess were disease duration, mixed infection, presence of septicemia, elevated bilirubin and alkaline phosphatase. Conclusions: In contrast to prior report that the E. coli was the most common pathogen in liver abscess, we found that K. pneumoniae was the most common organism cultured in liver abscess. Diabetic patients have more complications and higher mortality than patients without diabetes. Early detection and proper treatment are needed to improve the outcome for diabetic patient with liver abscess.

易東 禹倬思想의 硏究

오석원 安東大學附設 安東文化硏究所 1984 安東文化 Vol.5 No.-

The purpose of this thesis is to research on the characteristics of Yeok-Dong's(易東) thought. He was one of the outstanding Neo-Confucinists who practiced the thought of righteousness at the end of Koryo. In order to accomplish the objective set up, I have studied his personality through his life and historical back ground of his term. I have surveyed the relations of his teacher and student and the essence of his Neo-Confucianism to understand the basis of his learning. Finally, I searched the practice of his Righteousness and its influence on the later generations. The essence of his thought and his role in the history of Confucianism may be summarized as follows. (1) He subjectively accommodated the doctrines of Chu-Tzu(朱子) that had been introduced China at the end of Koryo and played the original role of the later Confucians through his full understanding and conveyance of Neo-Confucianism. (2) He had a thorough knowledge of the Book of Changes, especially Cheng-Tzu's Exposition(程傳). (3) He broke down the irrational and superstitious customs, which was prevalent at the end of Koryo and established the new ethos. (4) His thought of righteousness that aimed to embody the cause of justice gave an influence on the Confucianists in Yi dynasty. Especially, his scholarship and virtue exerted a great effects on Toe-Gye(退溪). (5) Nodays we can discover the new values in his thought of righteousness.

외배엽 이형성증 환자의 임상적 치험례

오소희,권순원,김종수,김용기,임헌송 대한소아치과학회 2000 大韓小兒齒科學會誌 Vol.27 No.2

Ectodermal dysplasia(외배엽 이형성증)은 외배엽성 기관에 한가지 이상의 선천적 이상소견을 특징으로 하는 질환이다. Ectodermal dysplasia는 약 120종류 이상이 보고되고 있고, 이 중 Hypohidrotic ectodermal dysplasia가 가장 잘 알려져 있으며 이는 성염색체 열성인자에 의해 유전되며 남성에서 호발한다고 한다. 임상증상으로는 무한증, 감모증, 무치증 혹은 핍지증이 가장 특징적이다. 이외에도 무피지증, 손톱이형성증, 가늘고 성긴 머리카락, 두드러진 이마, 안장코, 돌출된 안와상부, 입술의 돌출과 함께 피부가 건조하고 땀샘이 결핍되어 있어서 더위를 참지 못하고 발열이 일어나기 쉽다. 본 증례의 환자는 단국대학교 치과병원 소아치과에 내원한 6세 6개월된 남아로써 무치증을 보이는 Hypohidrotic ectodermal dysplasia로 진단되었고 환자의 심미적, 기능적 결함을 해소하기 위해 총의치로 치료를 시행하는 동안 다소의 지견을 얻어 이를 보고하는 바이다. 주요어 : 외배엽 이형성증, 무치증, 총의치

Merkel cell carcinoma with Bowen`s disease : review of Merkel cell polyomavirus in pathogenesis

( So Min Lyu ),( Seung Hyun Cheong ),( Ji Yeon Byun ),( Hae Young Choi ),( Chee Won Oh1 ) 대한피부과학회 2012 대한피부과학회 학술발표대회집 Vol.64 No.1

파노라마방사선사진에서 석회화가 발견되는 경동맥의 협착 정도

조소양,오원만,윤숙자,윤웅,이재서,Juan M. Palomo,강병철 대한구강악안면방사선학회 2009 Imaging Science in Dentistry Vol.39 No.3

Purpose : This study aimed to investigate the luminal stenosis of the internal carotid artery with calcification detected on panoramic radiographs. Materials and Methods : This study used fifty carotid arteries of 36 dental patients whose panoramic radiograph and computed tomography angiography (CTA) revealed the presence of carotid artery calcification. A neuroradiologist interpreted CTA to determine the degree of stenosis of the internal carotid arteries. The degree of stenosis was stratified in four stages; normal (no stenosis), mild stenosis (1-49%), moderate stenosis (50-69%) and severe stenosis (70-99%). Results : Among the fifty carotid arteries with calcification detected on both panoramic radiography and CTA, 20 carotid arteries (40%) were normal, 29 carotid arteries (18%) had mild stenosis, 1 carotid artery (2%) had moderate stenosis, and there was none with severe stenosis. Conclusion : Sixty percent of the carotid arteries with calcification detected on both panoramic radiography and CTA had internal luminal stenosis, and two percent had moderate stenosis. When carotid atheroma is detected on panoramic radiograph, it is possible that the dental patient has luminal stenosis of the internal carotid artery. (Korean J Oral Maxillofac Radiol 2009; 39 : 157-61)

고액 상평형의 측정과 추산 연구

박소진,박영신,황태원,한규진,오종혁,원동복 忠南大學校 産業技術硏究所 2001 산업기술연구논문집 Vol.16 No.2

정적인 융점측정 방법으로 benzene+n-dodecane, cyclohexane+phenol, phenol+water, water+sulfolane 및 diethylcarbonate+nitrobenzene계에 대한 고액 평형을 측정하였다. 측정된 고액평형 데이터는 문헌값과 modified UNIFAC에 의해 예측된 값과 비교하였으며, 추산값과 실험값은 ±1.61K 범위에서 잘 일치하였다. 본 연구에서 고찰된 diethylcarbonate의 융점은 기존문헌치와 큰 편차를 보여 재검증이 필요하다. Solid-liquid equilibrium(SLE) data were measured for benzene+ n-dodecane, cyclohexane+phenol phenol+water, water+sulfolane, and diethylcarbonate+ nitrobenzene systems by using static melting point measuring method. Measured SLE data were compared with the literature values and also compared with the values predicted by modified UNIFAC(Dortmund) equation. The experimental results are in good agreements with the published and estimated values, and the average deviation between the experimental values and the calculated values is ±1.16K. The measured melting point of diethylcarbonate shows some difference from literature value, and it will be certified through other experimental data for different systems.

시ᆞ도 건강가정지원센터의 운영모형 개발 연구 : 역할 및 조직을 중심으로 It's Roles and Organization

장진경,오제은,한은주,류진아,원소연 한국가족관계학회 2006 한국가족관계학회지 Vol.11 No.1

Reactive perforating collagenosis with leukocytoclastic vasculitis

( Ju Yun Woo ),( So Min Lyu ),( Seung Hyun Cheong ),( Ji Yeon Byun ),( Hae Young Choi ),( Chee Won Oh1 ) 대한피부과학회 2012 대한피부과학회 학술발표대회집 Vol.64 No.1

밀폐형 온실의 과습 조건과 무선통신 성능 관계 규명

김태균, 송정원, 박소정, 오종우 忠北大學校 農業科學硏究所 2017 農業科學硏究 Vol.33 No.1

In order to utilize the ubiquitous sensor network technology, it is necessary to identify the communication characteristics of the sensor node. The purpose of this study is to investigate the wireless performance to be related the environment (i.e. humidity) which can cause data loss in the greenhouse environment. The performance of wireless communication was conducted in the constant temperature and humidity device. The results of performance for Zigbee communication were not affected by the humidity. The Zigbee communication without the data loss would be more effective to control the environment in the greenhouse.

수종의 치과용 수복재료 및 시멘트의 radiopacity

정현주,강병철,오원만,양홍서 大韓口腔顎顔面 放射線學會 1994 Imaging Science in Dentistry Vol.24 No.1

The radiopacity of six composite resins, three resin luting cements and ten filling materials were studied. The purpose was to obtain an indication of radiopacity value of different brands within each of these groups of materials and to show differences in radiopacities of filling materials and natural tooth structures. On radiographs, the optimal densities of standardized samples were determined by computer imaging system and radiopacity values of the materials were expressed in millimeter equivalent aluminum. Within the groups of materials studied, there was considerable variation in radiopacity. The composite resins of P-50, Z100 and Prisma AP.H displayed much higher radiopacities than aluminum. Panavia resin cement was shown to be similarly radiopaque to aluminum. Generally, the radiopacity of base and filling materials appeared to be higher than that of the enamel and dentin. If materials with substantial difference in radiopacity are used in combined applications for restorative treatment of teeth, lower radiopacity can interfere with the diagnosis and detection of gaps near the restoration.