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Sivakumar, T,Kumar, R Sambath,Perumal, P,Vamsi, MLM,Sivakumar, P,Kanagasabai, R,Baskaran, MV,Karki, Subhas S,Mazumder, UK,Gupta, M Kyung Hee Oriental Medicine Research Center 2005 Oriental pharmacy and experimental medicine Vol.5 No.4
The plant Bryonia laciniosa (Family: Cucurbitaceae) has been indicated for the treatment of various diseases one among which is cancer. The purpose of this study was investigating experimentally the possible anti-tumor effect and antioxidant role of Bryonia laciniosa leaves in animal model. The methanol extract of Bryonia laciniosa (MEBL) administered at the doses of 62.5, 125 and 250 mg/kg in mice for 14 days after 24 h of tumor inoculation. The effect of MEBL on the growth of transplantable murine tumor, life span of EAC bearing mice, hematological profile and liver biochemical parameters (lipid peroxidation, antioxidant enzymes) were estimated. Treatment with MEBL decreased the tumor volume and viable cell count thereby increasing the life span of EAC bearing mice and brought back the hematological parameter more or less normal level. The effect of MEBL also decreases the levels of lipid peroxidation and increased the levels of glutathione (GSH), superoxide dismutase (SOD) and catalase (CAT). The present work indicates that the methanol extract of Bryonia laciniosa exhibited significant antitumor and antioxidant activity in vivo.
Meat Quality and Physicochemical Trait Assessments of Berkshire and Commercial 3-way Crossbred Pigs
Sivakumar Allur Subramaniyan,강다래,Shah Ahmed Belal,조은소리,정종현,정영철,최양일,심관섭 한국축산식품학회 2016 한국축산식품학회지 Vol.36 No.5
In this study, we compared qualities and physiochemical traits of meat from Berkshire (black color) pigs with those of meat from 3-way Landrace (white color) × Yorkshire (white color) × Duroc (red color) crossbred pigs (LYD). Meat quality characteristics, including pH, color, drip loss, cooking loss, and free amino acid, fatty acid, vitamin, and mineral contents of longissimus dorsi muscles, were compared. Meat from Berkshire pigs had deeper meat color (redness), higher pH, and lower drip loss and cooking loss than meat from LYD pigs. Moreover, meat from Berkshire pigs had higher levels of phosphoserine, aspartic acid, threonine, serine, asparagine, α-aminoadipic acid, valine, methionine, isoleucine, leucine, tyrosine, histidine, tryptophan, and carnosine and lower levels of glutamic acid, glycine, alanine, and ammonia than did meat from LYD pigs. The fatty acids oleic acid, docosahexaenoic acid (DHA), and monounsaturated fatty acids (MUFA) were present in significantly higher concentrations in Berkshire muscles than they were in LYD muscles. Additionally, Berkshire muscles were significantly enriched with nucleotide components (inosine), minerals (Mg and K), and antioxidant vitamins such as ascorbic acid (C) in comparison with LYD muscles. In conclusion, our results show that in comparison with LYD meat, Berkshire meat has better meat quality traits and is a superior nutritional source of all essential amino acids, monounsaturated fatty acids, vitamin C, and minerals (Mg and K).
Behaviour of Cold Formed Steel Built-Up Channel Columns Strengthened Using CFRP
Sivakumar Naganathan,H. G. Nahushananda Chakravarthy,Noor Amalina Anuar,Sreedhar Kalavagunta,Kamal Nasharuddin Bin Mustapha 한국강구조학회 2020 International Journal of Steel Structures Vol.20 No.2
This paper presents experimental findings of carbon fibre reinforced polymer (CFRP) strengthened cold-formed steel built-up channels subjected to axial load. In order to sensitively detect the buckling strengths and failure modes, twenty-four built-up columns were tested in which twelve columns were unadorned and another twelve columns were strengthened using CFRP sheets. The columns were tested for ultimate load, lateral displacement and failure modes. Tension coupon tests were conducted to determine the material properties of test specimens. The experimental results were compared with the design load calculated according to AISI S100-16 specification and are found to be in good agreement. It is established that the use of CFRP for strengthening increases the ultimate load and delays the buckling.
Sivakumar Rathinavelu,Satya Sai Pavan,Senthilkumar Sivaprakasam 한국생물공학회 2023 Biotechnology and Bioprocess Engineering Vol.28 No.1
Hyaluronic acid (HA), a glycosaminoglycan polymer, is widely used in the biomedical and cosmetic industries. Due to highly viscous nature of the HA fermentation broth, it is difficult to capture the dynamics of its bioprocess with physical sensors in real-time. The goal of this study was to track non-invasively the state variables involved in HA production process and deducing the critical process parameters based on the recorded process inputs. The framework employed in this study is based on a hybrid model that predicts HA and biomass concentration using online bioreactor data (pH, DO%, %CO2 evolved, feed rate, and agitation rate) to ensure real-time tracking of HA bioprocess dynamics. A HA fermentation dataset with data from historical batches and freshly performed fedbatch runs for various specific growth rate set-points (μsp) was created. The dataset was used to train the hybrid model, which was then used to predict biomass and HA concentration for test runs, with a mean squared error of prediction ranging from 0.018 to 0.049 (g/L)2. Furthermore, recurrent neural networks were evaluated in forecasting the specific growth rate (μ) and HA productivity rate (qHA) to observe the desired process trajectory. The current study addressed the scope of application of hybrid model based soft-sensor to predict the trend of process parameters of HA fermentation.
Drying and energy aspects of tapioca sago processing-An experimental field study
Sivakumar R.,Elayaperumal A.,Saravanan R. 대한기계학회 2017 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.31 No.6
The drying characteristics of tapioca sago were studied using four different drying methods--Open sun drying (OSD), Conveyor beltdrying (CBD), Bin drying (BD) and Fluidized bed drying (FBD)--in an industry located in Tamilnadu, India (Latitude: 11.494347° N;Longitude: 78.272264° E). The BD and FBD dryers were designed and fabricated as pilot scale models in the laboratory with respectivecapacity of 5 kg/h and 10 kg/h; CBD (1000 kg/h) and OSD are the commercial drying operations currently employed in industrial processing. The drying time, energy and exergy aspects of all the drying methods were compared along with the achieved final moisture content,color and quality of the dried products. The highest Energy utilization ratio (EUR) was found in CBD and FBD in the range of 20-76 % and 10-67 %, respectively. The exergy efficiency was initially low in all the cases but increased to 80 % towards the end of thedrying process.
Effect and design of Mn2+ doped ZnO nanostructures for photodegradation and energy storage devices
Sivakumar S.,Robinson Yengkokpam 한국물리학회 2023 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.82 No.12
This paper studies the synthesis of Zn1-xMnxO (x=0.00, 0.03, 0.06) nanoparticles using the co-precipitation method. The structural, morphological and optical properties were characterized by XRD, FTIR, SEM, HR-TEM and UV–Visible DRS analysis. The structural analysis indicated a hexagonal shape with good crystallinity of the samples. The FTIR absorption peaks confrmed the formation of Zn–O bonding. The surface morphology and particle size were observed by SEM and HRTEM analysis. The EDS spectra determined the presence of elements Zn, Mn, and O in the samples. The optical band-gap of Mn-doped nanoparticles decreased with increasing concentration from 3.27 eV to 3.09 eV. The photocatalytic activity has been observed with methylene blue (MB) dye under solar irradiation. The Zn0.94Mn0.06O (Mn=0.06) nanoparticles photocatalyst has the highest degradation efciency at 94.08% within 180 min. This result shows that the Mn-doped ZnO enhanced the performance of the photocatalytic activity. In electrochemical performance analysis, undoped and Mn-doped electrodes have been studied 10 mV/s to 100 mV/s scan rate. Mn-doped electrodes decrease the specifc capacitance due to low surface area. However, all the undoped and Mn-doped electrodes possess reduction and oxidation peaks, which is considerable for suitable electrode materials for energy storage devices.