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Park, Jae Hyeok,Lee, Chang-Ha,Joo, Ji Bong,Bae, Dal-Hee,Shun, Dowon,Moon, Jong-Ho,Park, Young Cheol,Shin, Jong-Seon,Choi, Young-Chan,Jung, Doo-hwan,Park, Jaehyeon Taylor Francis 2016 Drying technology Vol.34 No.9
<P>Upgrading low-rank coal (LRC) through various strategies is always an important issue. Here, we report the production of hybrid coals and an evaluation of their characteristics for use as a fuel in power plants. The hybrid coals (HCKs) were prepared by a combination of drying and biomass impregnation into an Indonesian LRC followed by a precarbonization process. We used a top-spray fluidized-bed reactor for drying, biomass impregnation, and precarbonization to produce hybrid coals that have improved fuel characteristics in terms of heating value, moisture readsorption, and combustion patterns. A systematic study reveals that experimental parameters, such as a bed temperature, bioliquid spraying procedure, and precarbonization temperature strongly influence the characteristics of the resulting hybrid coal, meaning that they have an important role in upgrading LRC. In particular, the hybrid coal prepared by a process of simultaneous drying and bioliquid spraying followed by precarbonization at 200-300 degrees C showed high contents of fixed carbon, an improved heating value, lower moisture adsorption, and single combustion patterns in which the characteristics were dramatically upgraded for practical use as a fuel in power plants. In addition, the simultaneous process using a fluidized-bed reactor has great potential because it can achieve process simplification, reduce manufacturing costs, and handle coal particles easily.</P>
흉수의 감별에 있어서 procalcitonin과 C-반응성단백의 유용성
김상하 ( Sang Ha Kim ),박주영 ( Joo Young Park ),박현숙 ( Hyun Sook Park ),서희석 ( Hee Seok Seo ),김신태 ( Shin Tae Kim ),김종환 ( Chong Whan Kim ),이부길 ( Bu Ghil Lee ),이석정 ( Seok Jeong Lee ),이선녕 ( Shun Nyung Lee ),노진규 대한결핵 및 호흡기학회 2007 Tuberculosis and Respiratory Diseases Vol.63 No.4
연구 배경: 흉수의 감별을 위해 염증지표로 알려진 procalcitonin과 CRP를 흉수와 혈청에서 각각 측정하여, 삼출액과 여출액의 감별과 삼출성 흉수의 다양한 원인들에 대한 감별에 유용한지 확인하고자 하였다. 대상 및 방법: 2005년 10월 1일부터 2006년 9월 30일까지 흉수로 입원하였거나 입원 중에 흉수가 발생하였던 총 198명을 전향적으로 연구하였으며, 원인 질환으로 한 가지의 정확한 진단이 가능하였던 178명을 분석하였다. 악성 흉수 57명, 결핵성 흉수 51명, 부폐렴성 흉수 31명, 농흉 5명, 기타 원인의 양성 흉수 7명과 여출성 흉수 27명이었으며, 대상 환자의 혈청과 흉수에서 procalcitonin과 CRP를 포함한 측정값을 비교 분석하였다. 결과: 흉수 procalcitonin과 CRP는 여출액과 비교하여 삼출액에서 유의한 증가를 보였고, 흉수 CRP가 2.06 mg/dL 이상일 때 특이도 96.3%, 민감도 45.0%로 삼출액을 감별할 수 있었다. 악성 흉수와 비교하였을 때에도 흉수 procalcitonin과 CRP는 양성 흉수에서 유의한 증가를 보였고, 흉수 CRP가 2.28 mg/dL 이상일 때 특이도 86.0%, 민감도 53.2%로, 흉수 procalcitonin이 0.11 ng/mL 이상일 때 특이도 84.2%, 민감도 40.4%로 양성 흉수를 감별할 수 있었다. 또한 흉수 procalcitonin은 비결핵성 흉수에서 유의한 증가를 보였다. 결론: 흉수에서 CRP와 procalcitonin을 측정하는 것은 삼출액과 여출액의 감별뿐 아니라 삼출성 흉수의 다양한 원인들 감별 등에 보조적으로 사용하기에 유용하다. Background: Malignancies are a common and important causes of exudative pleural effusions. Several tumor markers have been studied because the pleural fluid cytology and pleural biopsy specimens do not provide a diagnosis in a high percentage of malignant effusions. In an attempt to overcome this limitation, procalcitonin and C-reactive protein (CRP) in pleural effusions and serum, which are known to be inflammation markers, were measured to determine if they can differentiate an exudate from trasndate as well as the diverse causes of exudative pleural effusion. Methods: 178 consecutive patients with pleural effusion (malignant 57, tuberculous 51, parapneumonic 31, empyema 5, miscellaneous benign 7, transudative 27)were studied prospectively. The standard parameters of pleural effusion and measured serum and pleural procalcitonin were examined using in immunoluminometric assay. The level of CRP in serum and pleural fluid was determined by turbidimetric immunoassay. Results: The pleural procalcitonin levels in the exudate were significantly higher than those in the transudate, 0.81±3.09 ng/mL and 0.12±0.12 ng/mL, respectively (p=0.007). The pleural CRP levels were significantly higher in the exudate than the transudate, 2.83±3.31 mg/dL and 0.74±0.67 mg/dL, respectively (p<0.001). The pleural procalcitonin levels in the benign effusion were significantly higher than those in the malignant effusion, 1.15±3.82 ng/mL and 0.25±0.92 ng/mL, respectively (p=0.032). The pleural CRP levels were significantly higher in the benign effusion than in the malignant effusion, 3.68±3.78 mg/dL and 1.42±1.54 mg/dL, respectively (p<0.001). The pleural procalcitonin levels in the non-tuberculous effusion were significantly higher than those in the tuberculous effusion, 1.16±3.75 ng/mL and 0.13±0.37 ng/mL, respectively (p=0.008). Conclusion: Measuring the level of procalcitonin and CRP in the pleural fluid is helpful for differentiating between transudates and exudates. In addition, it is useful for differentiating between benign and malignant pleural effusions. (Tuberc Respir Dis 2007; 63: 353-361)
김신태 ( Shin Tae Kim ),이선녕 ( Shun Nyung Lee ),이석정 ( Seok Jeong Lee ),정필문 ( Pil Moon Jung ),박홍준 ( Hong Jun Park ),신명상 ( Myung Sang Shin ),김종환 ( Chong Whan Kim ),이부길 ( Bu Ghil Lee ),김상하 ( Sang Ha Kim ),리원 대한결핵 및 호흡기학회 2007 Tuberculosis and Respiratory Diseases Vol.63 No.6
Mycoplasma pneumoniae (M. pneumoniae) is the leading cause of pneumonia in older children and young adults. Normally, it does not progress to a condition requiring hospitalization but improves spontaneously or has a mild clinical course. We report two cases of M. pneumoniae pneumonia with different clinical manifestations from the normal course. The patients were young healthy individuals. The diagnoses were made by serology. However, it could not be determined beforehand that they had M. pneumoniae pneumonia. Based on the empirical treatment strategy of severe community acquired pneumonia, the patients were treated with broad-spectrum antibiotics including cephalosporin, quinolone and macrolide. After administering the antibiotics, they showed a gradually favorable clinical course and recovered without residual complications. A M. pneumoniae infection should be considered as a cause of severe community acquired pneumonia, and empirical treatment targeting this organism might be helpful in treating patients with the severe manifestation. (Tuberc Respir Dis 2007;63:515-520)
Glucose Metabolism Influences Cytoplasmic Maturation in Porcine Oocytes
Bao Yuan,Shuang Liang,Jiabao Zhang,Jeong-Woo Kwon,Shun-Ha Park,Hai-Yang Wang,PIAO XUAN JING,Xiang-Shun Cui,Nam-Hyung Kim 한국수정란이식학회 2016 한국수정란이식학회 학술대회 Vol.2016 No.10
In the present study, we examined potential roles of glucose and pyruvate in nuclear and cytoplasmic maturation of porcine oocytes. In the presence and absence of 10% porcine follicular fluid (PFF), either 5.6 mM glucose or 2mM pyruvate effect on meiotic maturation and followed development ability. However, DOs doesn't take full advantage of the glucose in medium, only pyruvate can increase MII rate and follow early embryo development ability significance. COCs were matured with 200 uM pentose phosphate pathway (PPP) inhibitor (dehydroepiandrosterone, DHEA) or 2 μM glycolysis inhibitor (iodoacetate, IA), significantly lower levels of GHS in the DHEA an IA treated oocytes and the levels of ROS were higher significantly in the DHEA treated oocytes, treatment with DHEA significantly reduced the intra-oocyte ATP and NADPH level. Blastocysts from DHEA or IA treated group also presented higher apoptosis levels, meanwhile, the percentage of proliferating cells was dramatically lower than the non-treated group. In conclusion, our results suggest that 10% PFF promoted oocytes make full use of energy, glucose metabolism during in vitro maturation inseparable from the cumulus cells, PPP and glycolysis promoted porcine oocytes cytoplasmic maturation by supplying energy and reducing oxidative stress.