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Identification of Multi-Input Multi-Output Wiener-type Nonlinear Systems
Yuzuru Shiotani,Yasuhide Kobayashi 제어로봇시스템학회 2009 제어로봇시스템학회 국제학술대회 논문집 Vol.2009 No.8
A Wiener model consists of alinear dynamic system in followed by a static nonlinearity. The Wiener model are widely used to represent nonlinear systems, and the multiple-input multiple-output(MIMO) Wiener model appears frequently in many nonlinear systems. Therefore, it is proposed that the identification method of the MIMO Wiener model with two or more linear dynamic subsystems, whose outputs are transformed by multiple-input static nonlinearities. The linear dynamic subsystems are represented by the MIMO state-space representation. The MIMO static nonlinearities are expressed by the artificial neural networks which have the ability to learn the complex nonlinear relationships.
Nerve Blocking Techniques of Pain Clinic
시오타니 마사히로,Shiotani, Masahiro The Korean Journal of Pain 1992 The Korean Journal of Pain Vol.5 No.1
A total of 578,886 nerve blocks were performed during a period of 28 years. Based on our experience, we introduced the concept of compartment block, and then improved our technique of nerve blocking. If the location of a compartment was defined by injecting a contrast medium under fluoroscopic monitoring, the effect of nerve block could be estimated. As a result, we can safely perform nerve blocks with alcohol within a short period of time.
Numerical Simulation of Ballast Water Exchange
Koichi KAMADA,Kiyokazu MINAMI,Shigeaki SHIOTANI,Kuniaki SHOJI 한국항해항만학회 2006 한국항해항만학회 학술대회논문집 Vol.2006 No.-
In February, 2004, at International Maritime Organization (IMO), LONDON, a new international convention “International Convention for the Control and Management of Ship’s Ballast Water and Sediment 2004" was adopted. It is called “Ballast Water Management Convention (BWM)". Ballast water means charged seawater or fresh water in ship’s special tanks (ballast tank) to keep safety navigation and ship’s maneuverability. However, from 1980, it was point out the serious problem for marine ecosystem and human life that ballast water includes harmful marine species (and small organisms) and these species are also discharged along with ballast water. These species were released with discharged ballast water in water areas, where species are different from discharged ballast water. The problem is that released species increase when released species are more powerful than native species and consequently, marine ecological system is destroyed in released water area. Authors have inspected the validity of the ballast water exchange using pumping-through method that is one of the methods of ballast water management. In this paper, the numerical simulation of the motion and density of the fluid at the time of exchange of the fluid in a 2-dimensional tank using the pumping-through method was carried out by using two different type numerical methods. One method is MPS method that is one of the particle methods. Other one is Finite Different Method (FDM). Authors were compared with result of two numerical method calculations and experiment result and reported some knowledge from these results.
( Tomoari Kamada ),( Yoshinori Fujimura ),( Kensuke Gotoh ),( Hiroshi Imamura ),( Noriaki Manabe ),( Hiroaki Kusunoki ),( Kazuhiko Inoue ),( Akiko Shiotani ),( Jiro Hata ),( Ken Haruma ) 대한소화기학회 2013 Gut and Liver Vol.7 No.1
Background/Aims: There have been few studies on the efficacy of proton pump inhibitors and the doses required to treat dyspeptic symptoms observed in clinical practice. The aim of this study was to compare the efficacy of different doses of omeprazole and different administration methods in Helicobacter pylori-negative, dyspeptic patients. Methods: Patients with chronic upper abdominal symptoms within the previous 3 months were randomly divided into three groups: a daily, omeprazole 20 mg treatment group (OPZ20, n=61); a daily, omeprazole 10 mg treatment group (OPZ10, n=72); and an on-demand omeprazole 20 mg treatment group (ondemand, n=62). After 4 weeks of administration of the drug, symptom improvement rates were evaluated based on the Overall Global Severity score. Results: The rates of symptom improvement after 4 weeks of treatment were 65.6% (40/61) in the OPZ20 group, 47.2% (34/72) in the OPZ10 group, and 50.0% (31/62) in the on-demand group. The OPZ20 group exhibited a significantly higher improvement rate (p=0.034) than the OPZ10 group. The OPZ20 group had significant improvements in regurgitation, postprandial fullness, vomiting, and bloating compared with the OPZ10 group. Conclusions: Daily treatment with 20 mg of omeprazole was efficient in treating upper abdominal symptoms. Trial registration: ClinicalTrials.gov, number UMIN000002621. (Gut Liver 2013;7:16-22)
( Ryo Katsumata ),( Manabu Ishii ),( Suni Lee ),( Yukiko Handa ),( Takahisa Murao ),( Minoru Fujita ),( Hiroshi Matsumoto ),( Takemi Otsuki ),( Akiko Shiotani ) 대한소화기기능성질환·운동학회(구 대한소화관운동학회) 2018 Journal of Neurogastroenterology and Motility (JNM Vol.24 No.3
Background/Aims Food interaction, including food hypersensitivity, plays a key role in the pathogenesis of irritable bowel syndrome with diarrhea (IBS-D). Since only a few studies have been reported about the relationship between food hypersensitivity and IBS-D, we elucidate the prevalence of serological food hypersensitivity in patients with IBS-D and the characteristics of gastrointestinal symptoms and serum cytokine profiles in patients with IBS-D and serological food hypersensitivity. Methods Immunoglobulin E (Ig E)-mediated serological food hypersensitivity and serum cytokine levels were evaluated using the multiple allergen simultaneous test evaluating food allergen-specific serum IgE and Luminex Milliplex Panel containing multiple fluorescencelabeled beads. Class 2 or above was considered as IgE-mediated food hypersensitivity positive. The gastrointestinal symptom rating scale was used to evaluate symptoms. Results We enrolled 92 subjects, including 60 with IBS-D and 32 healthy controls. The percentages of patients with IgE-mediated serological food hypersensitivity were not significantly different between the groups (controls = 28.1% and IBS-D = 33.3%). Serum IL-1β, IL- 6, IL-8, macrophage inflammatory protein-1alpha, and TNF-α levels were higher in patients with IBS-D than in controls. Serum concentration of TNF-α (43.4 vs 21.8 pg/mL, P = 0.009) was higher in patients with IBS-D without IgE-mediated serological food hypersensitivity than those with food hypersensitivity. Conclusions One-third of Japanese patients with IBS-D showed IgE-mediated serological food hypersensitivity. The serum cytokine profile differed and was characterized by lower inflammatory cytokine levels in IBS-D with IgE-mediated serological food hypersensitivity. Serological test regarding IgE-mediated food hypersensitivity can detect a certain cluster of IBS-D. (J Neurogastroenterol Motil 2018;24:415-421)