Time-Related Changes in Detrusor Overactivity in Awake Rats with Spinal Cord Injury Observed by Simultaneous Registrations of Intravesical and Intraabdominal Pressures

Jin, Long-Hu,Shin, Hwa-Yoan,Yoon, Seung-Hwan,Seong, Do-Hwan,Park, Chang-Shin,Lee, Tack,Yoon, Sang-Min Korean Continence Society 2011 International Neurourology Journal Vol.15 No.1

<P><B>Purpose</B></P><P>To compare the physical characteristics of detrusor overactivity (DO) induced by intravesical infusion of saline in awake, sham rats and rats with chronic spinal cord injury (SCI), by simultaneous registrations of intravesical and intraabdominal pressures.</P><P><B>Methods</B></P><P>Male Sprague-Dawley rats, normal or with a spinal vascular clip at the level of Th9, were investigated cystometrically 1 and 4 weeks after SCI. Intravesical pressure (IVP) and intraabdominal pressure (IAP) were recorded simultaneously to evaluate true DO. During the filling phase, the event of IVP rises, defined as increments that exceeded 2 cmH<SUB>2</SUB>O from baseline, were determined as DO according to the absence of simultaneous changes in IAP.</P><P><B>Results</B></P><P>All SCI rats exhibited DO during the filling phase, which was not shown in sham rats. The frequency and pressure of DO had a tendency to decrease with time. The DO frequency of SCI rats after 4 weeks (0.9±0.2 min<SUP>-1</SUP>) was decreased compared with that after 1 week (2.1±0.4 min<SUP>-1</SUP>; P<0.05). The DO pressure of SCI rats after 4 weeks (8.4±1.9 cmH<SUB>2</SUB>O) was decreased compared with that after 1 week (11.6±2.9 cmH<SUB>2</SUB>O; P>0.05).</P><P><B>Conclusions</B></P><P>Cystometric studies in awake male SCI rats showed some significant changes in bladder function after SCI. All SCI rats exhibited DO during the filling phase, and showed different physical characteristics of DO over the course of time. The neurological basis of these time-related changes remains poorly understood, but may provide important prognostic information about long-term urological management in SCI patients.</P>

인간포배기 배아의 효과적인 유리화 동결법의 개발을 위한 연구

이상민,이주희,이상원,이승민,윤산현,임진호,박흠대,이성구,Lee, Sang-Min,Lee, Ju-Hee,Lee, Sang-Won,Lee, Seoung-Min,Yoon, San-Hyun,Lim, Jin-Ho,Park, Huem-Dai,Lee, Seong-Goo 대한생식의학회 2003 Clinical and Experimental Reproductive Medicine Vol.30 No.3

Objective: The purpose of this study was to evaluate the survival rate of vitrified blastocyst according to the freezing vessels, equilibration time in cryoprotectant and artificial dehydration method. Methods: Human blastocysts were vitrified after loading onto the plastic straw, open-pulled straw (OPS), electron microscopy grid (EM grid) for 1.5 min or 3 min. They also were directly plunged into LN2 within 30sec. For artificial shrinkage of blastocysts, 36 gauge fine needle was pushed at the cellular junction of the trophectoderm into the blstocoele cavity until it shrank without damage of inner cell mass. Results: The survival rate of vitrified blastocysts on plastic straw, OPS, EM grid as freezing vessels were 26.7, 13.0 and 60.5%, respectively. The survival rate of EM grid was significantly higher than that of plastic straw and OPS (p<0.05). For 1.5 min equilibrium, the survival rates of early blastocyst (EB), middle blastocyst (MB) and late blastocyst (LB) were 64.4, 81.0, and 20.0% respectively. For 3 min equilibrium, the survival rates of EB, MB, and LB were 69.9, 50.0 and 57.5% respectively. The survival rates of EB and MB were significantly higher than that of LB in 1.5 min equilibrium group (p<0.05), however, the significance was not observed in 3 min equilibrium groups. In cytoplasmic shrinkage before vitrification, the survival rates of EB, MB and LB were 92.9, 100 and 75.9% respectively. The survival rate of MB was significantly higher than that of LB (p<0.05). The survival rates of vitrified blastocysts by artificial dehydration and slow-frozen blastocysts were not significantly different as 88.9 and 66.7%, respectively. Conclusion: This study showed that the vitrification of human blastocysts using EM grid and artificial dehydration is an effective method. Therefore, these methods would be an useful techniques for blastocyst cryopreservation.

중소기업 직접금융의 현황과 개선방안에 대한 연구

윤성민 釜慶大學校 1998 釜慶大學校 論文集 Vol.3 No.1

This paper aims to examine the causes of fund-raising difficultes of small and medium enterprises and propose some improvement programs for those difficulties especially in direct financing. The direct financing is a very profitable method that can improve fund-rasing difficulties of small and medium enterprises. These enterprises can raise long- term equipment funds through direct financing by credit only, with lower expenses than indirect financing. But in reality the portion of direct financing in fund-raising of small and medium enterprises is not much. They raise about 92% of the funds through indirect financing and only 7% through direct financing. Large enterprises get most(in 1998. 6, 98.7%) of the funds raised by the flotation of new issues and bonds in the Korea Stock Exchange. The fundamental cause that hinders small and medium enterprises in Korea from raising funds by the flotation of new issues and bonds is closely related to some existing systems of direct financial market. In other words small and medium enterprises have difficulties in accessing themselves to direct financial market, because they ccan not satisfy the rigorous institutional requirements in that markiet. Therefore to make direct financing of small and medium enterprises easier, some rigorous institutional requirements of direct financail market must be improved for accessibiility to that market.

남녀 청소년의 인터넷 이용, 공격성 및 인터넷 중독과 관련된 변인들

윤현민,박성연 이화여자대학교 생활환경대학 인간생활환경연구소 2005 인간생활환경연구소 논집 Vol.- No.4

This study examined variables as related to internet usage, aggression and internet addiction of adolescents with a sample of 386, 2nd-grade middle school students living in Seoul. The subject answered questionnaires on internet usage, aggression and internet addiction. The results indicated that boys spent more time on internet use and more involved in non-social type activity than girls; boys with higher proactive and relational aggression showed higher cyberspace aggression and girls with more internet use hours showed more reactive aggression; and internet addicted boys showed higher internet use hours, lower talking time with parents and higher non-social activity than non-addicted boys. On the other hand, internet addicted girls showed higher internet use hours, higher social-type activity and more internet friends than non-addicted girls. The results indicated that sex of adolescent, higher use internet hours, and social, and non-social type of internet use are the most important antecedent variables to predict internet usage, aggression and internet addiction.

두 마리의 고양이에서 발생한 복막 심낭막 횡격막 허니아의 수술적 치료

윤영민,정성목 忠南大學校 動物醫科學硏究所 2011 動物醫科學硏究誌 Vol.18 No.1

Two cats (5 years, intact female, Turkish Angora (case1) & 1 year, intact female, Persian Chinchinra (case2) admitted with the hisoty of cardiac abnormality. Two cats had the history of panting and increased respiratory rate. On physical examination, they had panting and right muffled heart sound. Thoracic radiography revealed increased cardiac silhouette, dorsal deviation of trachea, cylindric gas superimposition in cardiac silhouette, convex projection of the caudal cardiac silhoutte, and confluent silhoutte between heart and diaphragm. In ultrasonography, abdorminal viscera in pericardial sac were shown in two cats. They were diagnosed as peritoneopericardial diaphragmatic hermia(PPDH) based on diagnostic imaging examination. Herniorrhaphies and close perioperative care were performed for prevention of postoperative complication in two cats. PPDH in two cats were succesfully treated without postoperative complication.

충남대학교 기초과학분야의 효율적 육성에 관한 연구

윤화중,진성일,윤민중,윤혜수,이영하,최철규,이천배,신대현 충남대학교 자연과학연구소 1986 忠南科學硏究誌 Vol.13 No.2

Chungnam National University (CNU) is located in Daeduk Science Town, a center of science and technology in Korea, and it is expected to play an important role in the development of science in Korea. With this in mind, the basic natural sciences at CNU should be more actively supported in both education and research. Accordingly analysis and comparison of the basic science program at major college in Korea as well as those in the USA and Europe has been performed. The current cooperative relationship between CNU and research institutes in the science town has also been analyzed. This study has resulted in propositions to make more efficient the upbringing of the basic sciences at CNU, by focusing on the following points ; a) to improve academic affairs, b) to make graduate studies substantial, c) to secure highly qualified faculty members, d) to increase cooperation in research between CNU and reserch institutes, e) to enlarge research laboratories and acquire more equipment and facilities.

하도급 중소기업의 R&D 활동 결정요인

윤성민 한국중소기업학회 2003 中小企業硏究 Vol.25 No.1

본 연구의 목적은 하도급 중소기업 R&D 활동의 다양한 동기를 설명탈 수 있는 이론적 가설들을 제시하고, 이 연구가설들을 통계적으로 검정하는 것이다. 본 연구에서 제시하는 이론적 연구가설들에는 크게 기업의 특성, 제품유형 및 판매방범, 자금조달 측면, 기술적 측면의 네 가지 범주에 속하는 결정요인들이 포함되어 있다. 본 연구에서는 중소기업청·중소기업 협동조합중앙회(1999)의 『중소기업실태조사보고』의 원자료에 수록된 자료를 이용하여, 1-검정과 10git 및 probit 모형의 추정치레 대한 검정은 통하여 연구가설들의 통계적 타당성을 검정하였다. 이 두 모형의 추정결과로부터 기업규모와 기술적 복합성의 두 요인이 하도급 중소기업 R&0 합동에 대한 가장 중요한 결정요인이며 그 외에 수급의존도, 수출비중, 기술교류도 주요 결정요인이라는 사설을 알 수 있었다. The purpose of this paper is to present theoretical hypotheses on the determinants of R&D activities of subcontracting small firms and to test those empirically. The hypotheses Presented in this paper are consisted of firm characteristics, product type and sales method, funds raising method, and technological factors. We tested those hypotheses with the method of t-test and test on estimates of legit and probit model. And we used the raw data of 'Small and Medium Business Survey' of Small and Medium Business Administration(SMBA) and Korea Federation of Small and Medium Business(KFSB). We found that firm size and technological complexity are the most important determinants of R&0 activities of subcontracting small firms, and that subcontracting dependence, export ratio and technological interchange are also important determinants.

소화관내 이물에 대한 고찰

윤한덕,류진호,박주경,허탁,조석주,김성근,민용일 大韓應急醫學會 1997 대한응급의학회지 Vol.8 No.1

We analyzed records at Chonnam university hospital from Sep. 1. 1993 to Aug. 31. 1996 to assess clinical significance of the foreign body in the gastrointestinal tract. There were 133 episodes consisting of 79 pediatric and 54 adult patients as possible to review. In the pediatric patients, the coin was the most common cause of foreign body ingestion, while adult patients were usually caused by bones and meat. We removed foreign bodies in the oral cavity and oropharynx in 12 cases using direct laryngopharyngoscpy and forcep. Endoscopy was performed successfully in 47 of 51 patients in which was attempted; there were two complications composed of an aspiration pneumonia and a mediastinitis due to esophageal perforation. There were spontaneous passage of foreign bodies in 48 cases. We observed complications in 6 cases in which 4 cases needed operations due to complications. Foreign bodies which pass into the stomach can be observed for development of complications, as 94% of foreign bodies which reach the stomach spontaneously pass. Only 4 patients required interventions, which was done without mortality.

강진만 해역의 다모류 군집의 종조성 및 계절변동

윤성민,김춘철,서원일,황선영,이성훈,한경호,이우범 國立麗水大學校 環境問題硏究所 2004 環境硏究論文集 Vol.6 No.-

To detemine seasonal fluctuations in abundance and speices composition, polychaete samples were collected by Van Veen grab form March to November 2003 in Kangjin Bay. A total of 25,119.3 ind./㎡ polycaete were sampled and identified into 48 species. 25 families and 10 orders. Of the 10 orders. Phllodocida, Spionida, Eunicida and Sabellida accounted for approximately 79.9% of the polychaete fauna in this area. Phyllodocida, Nereidae, Nephtyidae ans Spionidae were dominant representing every moment 4 species. Of 48 species identified Neanthes japonica, Prionospio pinnate, Cirratulus cirratus and Palola siciliensis for 54.0% individuals collected. Season succession of dominant species was evident in study area: Neanthes japonica, Prionospio pinnata. Cirratulus cirratus. Nephtys oligobranchia in March, Neanthes japonica, Lumbrineris japonica. Cirratulus cirratus, Prionospio pinnata in May, Ncanthes japonica, Cirratulus cirratus, Lumbrineris nippnica. Lumbrineris japonica in August and Neanthes japonica, Prionospio pinnata, Laonice cirrata, Palola siciliensis in November, respectively. The diversity index was the highest value in March(H'=3.0059) and the lowest value in May(H'=2.7305). The eveness index was the highest in August(J=0.9184) and lowest in May(J=0.8524). The dominance index was the highest in May(D=0.3843) and the lowest in March(D=0.2275).

가구주 연령별 최저생계비의 계측과 분석

윤성민 釜慶大學校 1997 釜慶大學校 論文集 Vol.2 No.1

This study is to develop the measurement model of minimunm cost-of-living and to measure and analyze the minimum cost-of-living by householder's ages in Korea. The previously used models have the advantage of easy understanding, but also have the serious weakness as follows :(a) The previous models can not produce the reference data for living wages in the social wage system, because those are to measure minimum cost-of-living by family size(not by householder's ages). (b)In the previous models the definition of the minimum cost-of-living is not clear,so the minimum cost-of-living is measured arbitrarily. (c) The previous models use the Rowntree method. But this method is not objective, so the measurement results using that method can not be agreed by the wage negotiating bodies. A new model suggested in this study uses a duality relation of consumer's preference. And it modifies a theoetical model that is developed by KaKwani(1977) and van der Gagg and Smolensky(1982). We measured the minimum cost-of-living by householder's ages in Korea with a raw data of「Annual Report on the Family Income and Expenditure Survey」by using that model and analyzed the results. The new method presented in this paper is not arbitrary and can be agreed by the wage negotiating bodies.