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      • KCI등재

        Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting for Revascularization of Left Main Coronary Artery Disease

        Sangwoo Park,Seung-Jung Park,Duk-Woo Park 대한심장학회 2023 Korean Circulation Journal Vol.53 No.3

        Owing to a large-jeopardized myocardium, left main coronary artery disease (LMCAD) represents the substantial high-risk anatomical subset of obstructive coronary artery disease. For several decades, coronary artery bypass grafting (CABG) has been the “gold standard” treatment for LMCAD. Along with advances in CABG, percutaneous coronary intervention (PCI) has also dramatically evolved over time in conjunction with advances in the stent or device technology, adjunct pharmacotherapy, accumulated experiences, and practice changes, establishing its position as a safe, reasonable treatment option for such a complex disease. Until recently, several randomized clinical trials, meta-analyses, and observational registries comparing PCI and CABG for LMCAD have shown comparable long-term survival with tradeoffs between early and late risk-benefit of each treatment. Despite this, there are still several unmet issues for revascularization strategy and management for LMCAD. This review article summarized updated knowledge on evolution and clinical evidence on the treatment of LMCAD, with a focus on the comparison of state-of-the-art PCI with CABG.

      • KCI우수등재

        Dietary protease improves growth performance, nutrient digestibility, and intestinal morphology of weaned pigs

        ( Sangwoo Park ),( Jeong Jae Lee ),( Boung Mo Yang ),( Jin Ho Cho ),( Soyun Kim ),( Joowon Kang ),( Sejong Oh ),( Dong-jun Park ),( Rider Perez-maldonado ),( Jee-yeon Cho ),( Il-hun Park ),( Hyeun Bum 한국축산학회 2020 한국축산학회지 Vol.62 No.1

        This study was conducted to evaluate effects of dietary protease (PR) on growth performance, nutrient digestibility, and intestinal morphology of weaned pigs. A total of 75 weaned pigs [7.06 ± 0.18 kg of average body weight (BW); 28 day old] were randomly allotted to 3 dietary treatments in a randomized complete block design (blocks = BW and sex): a diet based on corn and soybean meal to meet the requirement of crude protein (CP) as a positive control (PC; CP = 24.49%), a low protein diet as a negative control (NC; CP = 22.51%), and NC + 0.02% PR. The PR used in this study was a commercial product containing 75,000 protease units/g derived from Nocardiopsis prasina produced in Bacillus licheniformis. Pigs were fed the dietary treatments for 6 weeks and the diets containing 0.2% chromic oxide for the last week of this study. Blood, feces, ileal digesta, and ileum samples were collected from randomly selected two pigs in each pen on respective time points. Measurements were growth performance, apparent ileal digestibility (AID) and apparent total tract digestibility (ATTD) of dry matter (DM), CP, and energy, frequency of diarrhea, packed cell volume (PCV), and ileal morphology of weaned pigs. Pigs fed PC and PR had higher (p < 0.05) final BW, average daily gain (ADG), and gain to feed ratio (G:F) during overall experimental period than those fed NC. Pigs fed PC and PR had higher (p < 0.05) AID or ATTD of DM, CP, or energy than those fed NC. Moreover, pigs fed PR had higher ratio between villus height and crypt depth (p < 0.05) and number of goblet cells (p < 0.05) than those fed NC. Addition of PR decreased (p < 0.05) frequency of diarrhea for the first two weeks after weaning compared with PC and NC. In addition, pigs fed PR had lower (p < 0.05) PCV on d 14 after weaning than those fed PC and NC. In conclusion, addition of PR in nursery diets with a low protein level significantly improved growth performance, nutrient digestibility, and intestinal morphology of weaned pigs

      • KCI등재후보

        2009 개정 초등 과학교과서의 과학사 도입 내용과 과학의 본성 분석

        박상우 ( Sangwoo Park ),정원우 ( Wonwoo Chung ),박경미 ( Kyungmi Park ) 경북대학교 과학교육연구소 2015 科學敎育硏究誌 Vol.39 No.2

        본 연구의 목적은 2009 개정 초등 과학교과서의 과학사 도입 내용과 이에 반영된 과학의 본성 요소를 분석하는 것이다. 분석을 위해 우선 2009 개정초등 과학교과서 8종을 새롭게 도입된 학년군과 내용 영역에 따라 과학사의 도입 자료와 제시형태를 도출하고 보다 체계적이고 심층적인 분석을 위해 과학사와 관련된 내용을 박세기, 이기영, 이면우(2011)가 개발한 3차원 조합 분석틀을 이용하여 과학사의 도입 내용을 분석하고, Leite(2002)가 개발하고 최윤희(2005)와 정고은(2013)이 수정한 분석틀을 보완하여 과학의 본성 요소를 분석하였다. 이연구의 분석 결과는 다음과 같다. 첫째, 2009 개정초등 과학교과서에 제시된 과학사 자료는 총 26개로 학년군 및 내용 영역별로 자료의 분포가 고르지않았다. 둘째, 전체 48개의 3차원 조합 유형 가운데에서 오직 13개 유형만 사용되고 있어 특정 유형에 편중하여 과학사를 도입하고 있었다. 셋째, 과학사 자료에 반영된 과학의 본성 요소가 학년 및 영역별로 고르게 분포되지 않았다. 결론적으로 과학사를 통해 과학의 본성을 이해하고 과학적 소양을 함양하기 위해서는 2009 개정 초등 과학교과서에서의 학년군과 내용 영역을 고려하여 다양한 유형의 과학사 자료를 도입해야 하고, 과학의 본성 요소를 적절히 반영하도록 교과서 도입에 있어 보다 다차원적인 접근이 이루어져야 할 것이다. The purpose of this study was to analyze the introduced contents and the nature of science on the history of science in elementary school science textbooks according to the 2009 revised curriculum. For this purpose, first of all, the frequency of contents of history of science in 8 kinds of science textbooks in elementary school is analyzed by grade cluster and content part. Analysis framework for analyzing the introduced contents on the history of science was characterized with three-dimensional combination of the context, the role and the types(Park, Lee, & Lee, 2011). Analysis framework for the nature of science on the history of science was developed by Leite(2002) and revised by Choi (2005) and Kim(2010) and complemented under one expert in science education. The results of this study are as follows: First, the frequency of contents of history of science in textbook is 26 and it were not equally distributed into science textbooks in elementary school as a result of the analysis by grade cluster and content part. Second, with three-dimensional combination framework only 13 kinds were used in all 48 different types through analyzing the textbooks. It implies that ways of introducing contents of history of science into textbooks were limited to certain types. Third, the nature elements of science were not equally distributed on the history of science in elementary school science textbooks. In conclusion, in order to understand the nature of science through the history of science and to foster scientific literacy ultimately, it implicates that it is need to present various kinds of the history of science for one theme in consideration about the grade cluster and content part. Also more multilateral approach is need to introduce equally distributed into textbooks to reflect the elements of the nature of science.

      • KCI등재

        과학사와 융합인재교육의 적용 실태와 과학사를 활용한 설계 기반의 융합인재교육 수업에 대한 초등교사들의 인식

        박상우 ( Sangwoo Park ),정원우 ( Wonwoo Chung ),박영관 ( Youngkwan Park ) 경북대학교 과학교육연구소 2016 科學敎育硏究誌 Vol.40 No.2

        이 연구는 과학 수업에서 과학사와 융합인재교육의 활용 실태와 과학사를 활용한 설계 기반의 융합인재교육 수업에 대한 초등교사들의 인식을 분석하는 것이다. 따라서 초등학교 과학 수업에서 과학사와 융합인재교육의 활용 실태와 과학사를 활용한 설계 기반의 융합인재교육 수업에 대한 교육적 가치를 알아보기 위해 설문지는 Shin & Han(2011)과 Lee & Shin(2014)의 연구와 Park et al.(2010)의 연구를 바탕으로 연구문제에 맞게 수정하여 총 20문항의 설문지를 개발하였다. 개발한 설문지는 D시와 G시 지역에 재직하고 있는 201명의 초등교사를 대상으로 설문을 실시하여 그 결과를 분석하였다. 이 연구의 결과 초등교사들은 과학 수업에서 과학사를 적극적으로 다루지 않으며, 주로 학생들에게 간단히 소개하면서 스스로 읽어보게 하였다. 초등교사들은 ‘충분하지 않은 시간’을 이유로 융합인재교육을 적극적으로 다루고 있지 않으며, ‘창의적 문제해결력’ 에 지도 중점을 두고 있지만 이 단계를 매우 지도하기 어려워하고 있었다. 또한 초등교사은 과학사를 활용한 설계 기반의 융합인재교육 수업의 교육적 가치에 대해서 매우 긍정적으로 인식하고 있었다. 특히 과학적 원리와 과거 과학자의 문제해결의 사례를 통해 학생들에게 창의적 설계와 문제해결의 아이디어와 실마리를 제공해 줄 수 있다고 인식하였다. 결론적으로 융합인재교육이 초등학교 현장에서 성공적으로 적용되기 위해서는 이와같은 초등교사들의 과학사와 융합인재교육의 활용실태에 대한 인식과 과학사를 활용한 설계 기반의 융합인재교육 수업의 교육적 가치에 대한 긍정적인 인식을 바탕으로 향후 보다 구체적인 과학사를 활용한 설계 기반의 융합인재교육 프로그램을 개발하고 적용하여 학교 현장에 보급할 필요가 있겠다. The purpose of this study was to analyze the utilization of history of science and STEAM and the elementary school teachers’ perceptions about design-based STEAM instruction applying the history of science in science class. To research the utilization of the history of science and STEAM in elementary science class, educational value of design-based STEAM instruction applying the history of science, the questionnaire was revised based on research conducted by Lee & Shin(2014), Park et al.(2010), Shin & Han(2011) and developed questionnaire a total of 20 questions. It was administered to reply the questionnaire to 201 teachers of elementary school in D and G area. The results of this study were as follows: elementary school teachers did not teach actively the history of science, made it read students by simply introducing himself. They did not teach actively STEAM due to not enough time(busy to take a magnitude). They were difficult to teach, but the most focused on the ‘Creative Problem-solving’ process. And elementary school teachers perceived positively about the educational value of design-based STEAM instruction applying the history of science. Especially, they perceived that it can help elementary school students find a hint for solving the problem through examples of cases of scientific principles and a scientist. In conclusion, it implicates that it is need to regard elementary school teachers’ perceptions on application of the history of science and STEAM, and develop specific design-based STEAM program applying the history of science in order to be applied successfully in elementary school for the STEAM settlement.

      • The Moderating Effect of Presenteeism in Relationship between Job Demands and Exhaustion of Korean Nurses: Secondary Data Analysis

        Sangwoo Park,Juhee Jeong,Youngjin Lee,Heejung Kim 한국간호과학회 2021 한국간호과학회 학술대회 Vol.2021 No.10

        Aim(s): This study aims to investigate the moderating effect of presenteeism between job demands and exhaustion among Korean registered nurses. Method(s): This study was the secondary data analysis from the Fifth Korean Working Conditions Survey(KWCS). The sample included 547 nurses. The variables were measured by the KWCS questionnaire including job-demand, presenteeism and exhaustion. Data were analyzed using descriptive statistics, independent t-test, ANOVA, multiple linear regression with SPSS 25.0 program. Result(s): Exhaustion among nurses was 2.90±0.90 and 25.7% of nurses answered that they experienced presenteeism over the past 12 months. Significant predictors for exhaustion were physical job demands (β=0.144, p=0.007) and work overload (β=0.125, p=0.019). There was a moderating effect of presenteeism between physical job demand and exhaustion (p=0.013). Conclusion(s): The higher the nurse’s physical job demands and work overload, the higher the level of exhaustion. When nurses experienced presenteeism, physical job demands increased the level of exhaustion. Therefore, it is required for nursing managers to manage presenteeism for nurses to reduce exhaustion.

      • Simultaneous mineralization and deposition of inorganic nanoparticles onto micropatterns with a perfluoropolyether-decorated surface as a passivating layer.

        Park, Soo-In,Park, Sangwoo,Kwon, Sunil,Lee, Sang-Yup American Scientific Publishers 2013 Journal of Nanoscience and Nanotechnology Vol.13 No.10

        <P>We achieved simultaneous mineralization and patterning of inorganic nanoparticles on micropatterns using peptide as a linker and perfluoropolyether (PFPE) as a passivating molecule. The peptide was used as a linker molecule immobilizing inorganic nanoparticles on the substrate and PFPE was exploited as a mask material preventing nanoparticle binding. These two substances were used as surface-modifying molecules for the positive and negative patterns, respectively. On the patterned surface, mineralization and selective deposition of inorganic nanoparticles (such as TiO2 and Cu2S) were achieved by exploiting the characteristics of the surface-modifying molecules. The aqueous precursors of inorganic sources were mineralized to the nanoparticles, and the mineralized nanoparticles were bound directly to the peptide-decorated positive pattern, while their deposition on the negative pattern was repelled because of the low surface energy of PFPE. The nanoparticle-bound surface was identified by making a sandwich structure with a fluorescece-decorated peptide and observing the surface topology. The nanoparticle layers retained their inherent electrical properties, suggesting potential applications in micro device fabrication. This study demonstrates that selective deposition of metallic and inorganic nanoparticles can be achieved with the use of PFPE and reactive peptides while keeping the original characteristics of the nanoparticles.</P>

      • SCOPUSKCI등재

        Prediction of the 10-year risk of atherosclerotic cardiovascular disease in the Korean population

        Sangwoo Park,Yong-Giun Kim,Soe Hee Ann,Young-Rak Cho,Shin-Jae Kim,Seungbong Han,Gyung-Min Park 한국역학회 2023 Epidemiology and Health Vol.45 No.-

        OBJECTIVES: Proper risk assessment is important for the primary prevention of atherosclerotic cardiovascular disease (ASCVD). However, no validated risk prediction tools are currently in use in Korea. This study sought to develop a 10-year risk prediction model for incident ASCVD. METHODS: Using the National Sample Cohort of Korea, 325,934 subjects aged 20-80 years without previous ASCVD were enrolled. ASCVD was defined as a composite of cardiovascular death, myocardial infarction, and stroke. The Korean atherosclerotic cardiovas cular disease risk prediction (K-CVD) model was developed separately for men and women using the development dataset and validated in the validation dataset. Furthermore, the model performance was compared with the Framingham risk score (FRS) and pooled cohort equation (PCE). RESULTS: Over 10 years of follow-up, 4,367 ASCVD events occurred in the overall population. The predictors of ASCVD included in the model were age, smoking status, diabetes, systolic blood pressure, lipid profiles, urine protein, and lipid-lowering and blood pressure-lowering treatment. The K-CVD model had good discrimination and strong calibration in the validation dataset (time-dependent area under the curve=0.846; 95% confidence interval, 0.828 to 0.864; calibration χ2=4.73, goodness-of-fit p=0.32). Compared with our model, both FRS and PCE showed worse calibration, overestimating ASCVD risk in the Korean population. CONCLUSIONS: Through a nationwide cohort, we developed a model for 10-year ASCVD risk prediction in a contemporary Korean population. The K-CVD model showed excellent discrimination and calibration in Koreans. This population-based risk prediction tool would help to appropriately identify high-risk individuals and provide preventive interventions in the Korean population.

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