Associations of serotonergic genes with poststroke emotional incontinence

Kim, Jae‐,Min,Stewart, Robert,Kang, Hee‐,Ju,Bae, Kyung‐,Yeol,Kim, Sung‐,Wan,Shin, Il‐,Seon,Kim, Joon‐,Tae,Park, Man‐,Seok,Cho, Ki‐,Hyun,Yoon, Jin‐ John Wiley Sons, Ltd 2012 INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY Vol.27 No.8

<P><B>Objectives</B></P><P>Poststroke emotional incontinence (PSEI) has been associated with serotonergic dysfunction. Polymorphisms of serotonin transporter (5‐HTT) and serotonin 2a receptor (5‐HTR2a) genes may regulate serotonergic signaling at brain synapses, and this study was to investigate associations with PSEI in an East Asian population.</P><P><B>Methods</B></P><P>In 276 stroke cases, PSEI was diagnosed by Kim's criteria. Covariates included age, gender, education, history of depression or stroke, current depression, and stroke severity and location. Genotypes were ascertained for 5‐HTT gene‐linked promoter region (5‐HTTLPR), serotonin transporter intron 2 variable number tandem repeat, 5‐HTR2a 1438A/G, and 5‐HTR2a 102 T/C. Associations with PSEI were estimated by using logistic regression models, and gene–gene interactions were investigated by using the generalized multifactor dimensionality reduction method.</P><P><B>Results</B></P><P>PSEI was present in 37 (13.4%) patients. The 5‐HTT gene‐linked promoter region <I>s</I>/<I>s</I> genotype was independently associated with PSEI. No associations with STin2 VNTR and 5‐HTR2a genes were found, and no significant gene–gene interactions were identified.</P><P><B>Conclusions</B></P><P>Stroke patients with 5‐HTTLPR <I>s</I> allele had higher susceptibility to PSEI, which underlines the potential role of serotonergic pathways in its etiology. Copyright © 2011 John Wiley & Sons, Ltd.</P>

Nanogenerators: Fully Rollable Transparent Nanogenerators Based on Graphene Electrodes (Adv. Mater. 19/2010)

Choi, Dukhyun,Choi, Min-Yeol,Choi, Won Mook,Shin, Hyeon-Jin,Park, Hyun-Kyu,Seo, Ju-Seok,Park, Jongbong,Yoon, Seon-Mi,Chae, Seung Jin,Lee, Young Hee,Kim, Sang-Woo,Choi, Jae-Young,Lee, Sang Yoon,Kim, Jo WILEY-VCH Verlag 2010 ADVANCED MATERIALS Vol.22 No.19

<B>Graphic Abstract</B> <P>The cover shows an image of fully rollable transparent nanogenerators synthesized using chemical vapor deposition grown large-scale graphene sheets as transparent electrodes and piezoelectric ZnO nanorod arrays. Sang-Woo Kim, Jae-Young Choi, and co-workers report on p. 2187 the electrical and structural stability of the nanogenerators, with excellent charge scavenging performance under external mechanical loads such as bending and rolling. This study shows that graphene-based nanogenerators are very promising for self-powered rollable transparent device applications. <img src='wiley_img_2010/09359648-2010-22-19-ADMA201090066-content.gif' alt='wiley_img_2010/09359648-2010-22-19-ADMA201090066-content'> </P>

예비유아교사 임용직전 교육프로그램 개발 및 교사역량에 미치는 효과

김연희 ( Yeon Hee Kim ),신인숙 ( In Sook Shin ),최성열 ( Sung Yeol Choi ) 한국아동교육학회 2013 아동교육 Vol.22 No.3

본 연구는 예비유아교사가 정교사로 임용되기 직전 교사로서의 역량을 강화하지 위한 교육프로그램을 개발하고 이 프로그램이 예비유아교사의 교사역량에 미치는 효과를 살펴보고자 하는 데 그 목적이 있다 이러한 목적을 달성하기 위하여 설정한 연구문제는 다음과 같다. 첫째, 예비유아교사 임용직전 교육프로그램 구성은 어떠한가? 둘째, 예비유아교사 임용직전 교육프로그램이 교육신념, 전문적 자질, 교사효능감에 미치는 효과는 어떠한가? 교사역량을 갖춘 유야교사가 되기 위한 예비유아교사 임용직전교육프로그램의 개발은 문헌고찰, 예비유아교사와 현직유아교사의 인식 조사, 전문가 의견 조사를 거쳐 프로그램의 목표 및 교육내용, 교수-학습 방법을 구성하였다. 예비유아교사 대상 임용직전 교육프로그램의 효과를 살펴보기 위하여 대구시내에 소재한 B 전문대학 유아교육과 3학년 재학생 30명을 실험집단, 30명을 비교집단으로 구분하였다. 실험집단을 대상으로 주 3회, 총 12회기에 걸쳐 실험을 진행하였다. 수집된 자료는 SPSS 18.0 프로그램을 이용하여 실험집단과 비교집단의 사전검사, 사후검사, 추후검사의 평균과 표준편차를 산출하고 시기별 점수 차이가 있는지 알아보기 위하여 집단과 시기를 독립변인으로 한 반복측정 분산분석(repeated measures ANOVA)을 실시하였다. 본 연구의 결과는 다음과 같다. 첫째, 예비유아교사의 교사역량을 향상시키기 위한 임용직전 교육프로그램은 교육신념, 전문적 자질, 개인적 자질, 교사효능감 증진을 위한 12회기 프로그램으로 개발되었다. 교수-학습 내용 및 방법은 교사역할에 대한 자신감 및 구체적 기술을 다양한 활동과 반성적 과정을 통해 학습할 수 있도록 구성하였다. 둘째, 예비유아교사 임용직전 교육프로그램은 교육신념, 전문적 자질, 개인적 자질, 교사효능감 증진에 긍정적인 효과가 있다. 본 연구를 통하여 예비유아교사에게 필요한 현장적응 역량 강화교육의 중요성이 강조된다. The purpose of this study was to develop an educational program for pre-service early childhood teachers and to investigate the program`s effects on the teachers` teaching competence. The research questions were as follows. First, what is the purpose, contents, teaching-learning methods, and the assessment of the educational program for pre-service early childhood teachers? Second, what are the effects of the program on teaching beliefs, professional disposition, and teaching efficacy of the pre-service early childhood teachers? The educational program for pre-service early childhood teachers was constructed through literature reviews, surveys on the perceptions of in-service and pre-service teachers, and interviews of early childhood professionals to develop the purpose, the contents, the teaching-learning methods, and the assessment of the educational program. The effects of the programs were investigated by carrying out an experLn1ental study. A total of 30 pre-service early childhood teachers were assigned to the experimental group and 30 pre-service early childhood teachers were assigned to the comparative group. The experimental group participated in 3 sessions per week for a total of 12 sessions. The teaching beliefs was examined by Moon`s (1993) scale, the personal and the professional disposition by Ki`s (2008) scale, and the leaching efficacy by Kim`s (2000) scale. The collected data were analyzed using SPSS 18.0. A pre-test, a post-test, and an afterward-test were carried out to compare the means of the experimental and the comparative groups using a repeated measures ANDV A. The results of this study were as follows. First, the teaching competence of pre-service early childhood teachers were composed of the teaching beliefs, the personal and the professional disposition, and the teaching efficacy. The educational program for pre-service early childhood teachers was developed for 12 sessions to promote the teaching competence through reflective and hands-on activities. Second, the experimental group`s teaching beliefs, personal and professional disposition and disposition and teaching efficacy improved by participating in the educational program developed by this study. The results of this study emphasize the importance of educating the early childhood pre-service teachers to promote their practical knowledge applicable to their teaching profession.

Topology and Control Scheme of OBC–LDC Integrated Power Unit for Electric Vehicles

Kim, Yun-Sung,Oh, Chang-Yeol,Sung, Won-Yong,Lee, Byoung Kuk Institute of Electrical and Electronics Engineers 2017 IEEE transactions on power electronics Vol. No.

<P>This paper proposes a novel integrated low-voltage dc-dc converter (LDC) and onboard battery charger (OBC) for electric vehicles (xEVs) that share heatsinks, terminals, sensing circuits, and circuit components between both parts. The proposed OBC-LDC integrated power unit (OLPU) can be simplified by modifying the internal connections of the vehicle, thus eliminating the cost of high-power cables. In addition, the OLPU decreases the number of circuit components and increases the total power density by combining or sharing heatsinks, terminals, sensing circuits, and circuit components. Further, the proposed circuit satisfies the performance characteristics of conventional OBCs and LDCs and can be operated as such. Moreover, a simultaneous charging method for both a high-voltage battery and a low-voltage battery is suggested through an additional operational mode that results from the integration. This paper also specifically describes the operating characteristics and the design method in each mode. Design considerations, including possible problems with the integrated circuit structure, are presented, and an additional compensation circuit is suggested to solve these problems. The prototype is built, and experiments are carried out to verify the performance and validity of the proposed power unit.</P>

Toxicological evaluation of extracellular vesicles derived from canine adipose tissue-derived mesenchymal stem cells (ASC-EVs)

Sung Bae Kim,Hyeon Yeol Ryu,Gyoo Il Kang,Hye Bin Bang,Hyung Taek Jeon,Byong Seung Cho,Sok Ho Kim,Moon Yong Song,Kyung Seuk Song 한국실험동물학회 2022 한국실험동물학회 학술발표대회 논문집 Vol.2022 No.7

Photoreactions of Quinonoid Compounds with Alkynes and Cyclic Olefins

Kim, Sung-Sik,Yoo, Dong-Yeol,Cho, In-Ho Korean Chemical Society 1988 Bulletin of the Korean Chemical Society Vol.9 No.4

Thermal Stability and Deposition Behaviors of Ru Thin Films Prepared by Using Metalorganic Chemical Vapor Deposition

Sang Yeol Kang,Hyeong Joon Kim,황철성,Ha Jin Lim 한국물리학회 2004 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.44 No.1

Ru thin films were deposited on Ta2O5 and TiN substrates by using metal-organic chemical vapor deposition (MOCVD) with cyclopentadienyl-propylcyclopentadienlylruthenium (II) [RuCp(i- PrCp)]. The thermal stability of the Ru lms, which were located between the diffusion barriers and the high-dielectric lms used as bottom electrodes, was investigated. We deposited Ti-doped Ru films to improve the thermal stability of the Ru films. We found that the increase in the surface roughness of Ti-doped Ru films with low Ti addition was suppressed during annealing. It seems that the TiOx phase formed at the grain boundary of the Ru grain inhibited growth of the Ru grain. We also improved the interface property of Ru/TiN through H2 annealing and found that the Ru-RuO2 film deposited on the TiN surface had more RuO2 phases than the Ru-RuO2 films deposited on Ta2O5 due to the different nucleation barriers for the deposition of Ru thin films.

Some results on convergence in distribution for fuzzy randomsets

Sang Yeol Joo,Gyeong Suk Choi,Joong Sung Kwon,Yun Kyong Kim 대한수학회 2005 대한수학회지 Vol.42 No.1

In this paper, we ¯rst establish some characterization of tightness for a sequence of random elements taking values in the space of normal and upper- semicontinuous fuzzy sets with compact support in Rp. As a result, we give some su±cient conditions for a sequence of fuzzy random sets to converge in distribution.

Photochemical Rearrangement of Chloranil

Kim, Sung-Sik,Yoo, Dong-Yeol,Cho, In-Ho,Shim, Sang-Chul Korean Chemical Society 1987 Bulletin of the Korean Chemical Society Vol.8 No.4

Irradiation of a solution of chloranil and cycloheptatriene, or 1,3-cyclohexadiene, in dichloromethane yielded unexpected photorearrangement products as the major product, while chloranil with cyclohexene gave the photorearrangement product as well as 1 : 1 adduct.

담배 연기발생과 Tipping 재료와의 상관성 연구

Kim, Young-Hoh,Lee, Young-Taek,Kim, Sung-Han,Kim, Chung-Ryul,Kim, Jong-Yeol,Shin, Chang-Ho,Lee, Keun-Hoi 한국연초학회 1998 한국연초학회지 Vol.20 No.1

In order to minimize the trial frequency in the new filter cigarette design, we studied the relationship between smoke yield and tipping materials of cigarette. A three levels full factorial design involving filament denier (X1,2.5-3.3d), Porosity of the acetate filter plug wrap (X2, 3,500-16,000CU) and porosity of the tip paper (X3, 400-1,200CU) was used. Three independent factors (Xl, X2, X3) were chosen for their effects on the various responses and the function was expressed in terms of a quadratic polynomial equation, Y : $\beta$o + $\beta$1Xl + $\beta$2X2 + $\beta$3X3 + $\beta$11Xl2 + $\beta$22X22+ $\beta$33X32 + $\beta$12X1X2 + $\beta$13XIX3 $\beta$23X2X3 which measures the linear, quadratic, and interaction effects. Twenty-nine trial numbers were obtained as a results of using a three levels full factorial design and it was analyzed by the multiple regression analysis with backward stepwise in STATISTICA/pc under restricted conditions. Tar yields of the cigarette was affected by porosity of tip paper (0.66), filament denier (0.47) and porosity of plug wrap (0.28) in the decreasing order, and linear effect of tip paper porosity (B3) and filament denier (91) were significant at a level of 0.01($\alpha$). The filament denier and tipping paper porosity interaction F ratio among three factors had a P-value of 0,000041, indicating higher interaction between these factors. Based on the analysis of variance, the model fitted for Tar (Y1) was significant at 5% confidence level and the coefficient of determination (0.96) was the proportion of variability in the data fitted for by the model.