[논문]해석방법에 따른 사각 RC 라멘교의 거동

진치섭,이승훈,엄장섭,배상현 釜山大學校生産技術硏究所 2006 生産技術硏究所論文集 Vol.65 No.-

본 연구에서는 사각(900°~450°) RC 라벤교를 2차원 보해석과 3차원 판해석으로 해석하였다. 연구 결과로부터 다음과 같은 결론을 얻었다. 슬래브 지점부의 단면력 집중에 따라,3차원 판해석에 의한 단면력은 2차원 보해석의 단면력보다 1.015~1.830배 크게 나타났다. 따라서 슬래브 지점부의 철근 보강 영역은 경사폭의 0.11~0.30배로 나타났다. 슬래브 최대 정모멘트 발생각과 라멘교 사각과의 상관관계를 살펴보면, 라벤교 사각 900° ~45°에 대하여 최대 정모벤트 발생각은 93° ~ 51°로 나타났다. 따라서 라벤교의 주인장 철근 이음장 위치는 최대 정모맨트 발생 구역 밖에들도록 해야한다.

외상 환자의 세포 면역학적 변화

지훈상,이한식,민진식 대한응급의학회 1995 대한응급의학회지 Vol.6 No.2

Thirty trauma patients admitted to our emergency center had lymphocyte phenotypic subsets characterized throughout hospital course. The immunosuppressive disease and CNS injury patients were exclude. There was no mortality in our studied cases. T-lymphocyte(CD-3), T helper(CD-4), T suppressor(CD-8) and B-lymphocyte(CD-19) were quantified by monoclonal antibodies and flowcytometric analysis. Results were analyzed on the day of admission 1st day, 2nd day, 4th day and 8th day among three groups: Injury severity score(ISS) below 15(n=10), 15-25(n=10), over 25(n=10). The patients were compared to 20 healthy controls. The immunologic depression was maximal on 2nd day and nearly recovered on 8th day. ISS over 25 group was most significantly depressed in all subset of T- lymphocyte, but ISS 15-25 group was slightly depressed less than ISS below 15 group. The B-lymphocyte was changed in similar pattern like as all subset of each ISS group, but the initial B-lymphocyte slightly increased comparing controls. Therefore the immunologic depression is affected by severity of trauma, and the severe and mild depression of immune system is included. The patterns of immune depression of T-lymphocyte and its subset were double peak in mild and severe trauma patients. The B-lymphocyte is stimulated in severe trauma patients during the initial stage of injury.

[논문]斜角을 고려한 곡선 Box Girder교의 거동에 관한 연구

박성진,이승훈,진치섭 釜山大學校生産技術硏究所 2003 生産技術硏究所論文集 Vol.62 No.-

일반적으로 국도상의 교량은 기존도로의 확장이나 주변지형의 영향 등을 많이 받기 때문에 기하학적 형상이 직선교보다 사교나 곡선교인 경우가 많다. 예를 들어, 고속도로 인터체인지 및 도심지 내의 입체교량 둥에서 교통의 흐름을 원활히 하기 위해서 곡선 교량이 본격적으로 설계 · 시공되고 있다. 또한 구조물의 현장조건에 따라서 사각(skew angles) 이 있는 곡선교의 시공이 불가피하게 되었다. 본 연구에서는 절판구조물로 구성된 단면형태를 가진 곡선교에서 사각의 크기 및 곡률변화에 따른 구조물의 거시적인 거동을 유한요소 범용 프로그램인 SAP2000을 사용하여 비교 · 분석하였다.

스프레드시트와 Green 정리를 이용한 철근 콘크리트 단주의 해석 및 설계

진치섭,한상중,엄장섭,이승훈 釜山大學校生産技術硏究所 1998 生産技術硏究所論文集 Vol.55 No.-

구조물 설게에서, 압축과 2축 휨을 동시에 받는 기둥 설계를 자주 접하게 된다. 이러한 부재의 해석과 설계는, 모멘트 평형에 따른 여러 변수들의 값을 동시에 구하기 위하여 반복적인 작업이 필요하기 때문에 많은 시간을 요구한다. 본 연구에서는 압축과 2축 휨을 받는 철근 콘크리트 단주를 해석 및 설계할 수 있는 컴퓨터 프로그램 COL2를 개발하였다. 프로그램 COL2는 스프레드시트 프로그램 중의 하나인 엑셀을 이용한 사용자 위주 환경의 프로그램으로 개발되었다. Green정리를 사용하여 임의 형상의 역학적 특성을 계산하였다. In structural design, columns subjected to combined compression and biaxial bending are frequently encountered. The analysis and design of such members, are both time consuming and demanding because an iterative procedure is reuqired in order to simultaneously evaluate a number of variables to achieve moment equilibrium. A computer program COL2 is developed to analyze and design reinforced concrete short columns subjected to combined compression and bizxial bending in this study. The program COL2 has been developed for user-friendly environment using MS-Excel one of the spreadsheets program. The mechanical properties of generic shapes was calculated by Green's theorem.

벤지딘계 염료제조 사업장 근로자의 벤지딘 폭로

노재훈,안연순,김규상,김치년,김현수 大韓産業醫學會 1995 대한직업환경의학회지 Vol.7 No.2

To evaluate the differences of benzidine exposure patterns of the workers in two benzidine-based dye manufacturing factories, the concentration of benzidine in air, blood and urine were measured. The air levels of benzidine dihydrochloride and benzidine-based dye were measured by high performance liquid chromatography with ultraviolet detector. Blood samples were collected at 3 hours after exposure and urine samples were collected at the end of shift. Blood and urine samples were analyzed by high performance liquid chromatography with electrochemical detector. The level of benzidine in reaction process (input, diazotization, and coupling) was 0.381±7950g/㎥. The blood benzidine was deteced in 25 workers among 38 in reaction process and their mean levels were 0.0153±.0376 ng/mg Hb. The urinary benzidine was detected for 11 workers among 38 workers in the reaction process. The level of benzidine-based dye in drying and packing process was 52.1748±14.4111g/㎥. The blood benzidine was deteced in 6 workers among 38 in drying and packing process and their mean levels was 0.0062±.0274 ng/mg Hb. The urinary benzidine was detected for 1 worker among 38 workers exposed to benzidine-based dye. The blood and urinary benzidine were detected in workers exposed to benzidine-based dye. Such results suggested that some part of benzidine-based dye was metaboized to benzidine. Therefore, some regulations for manufacturing and use of the benzidine-based dye are needed to prevent its hazards in industries.

忠南地域 屠畜豚의 肺病變으로부터 分離한 Actinobacillus pleuropneumoniae의 生物學的 및 免疫學的 特性

이종훈,장경수,장치훈,김일택,정용성,김귀현,전무형 충남대학교 수의과대학 동물의과학연구소 1996 動物醫科學硏究誌 Vol.4 No.-

An epidemiologic study on pleuropneumonia in the slaughter pigs(Chonan and Asan area, Chungnam province, Korea) during the period of January 1994 through December 1995 was conducted. Isolation of A. pleuropneumoniae was attempted in 425 pigs with pneumonic lesions. Biochemical properties, antimicrobial susceptibility, serotypes and pathogenicity of A. pleuropneumoniae isolates were investigated. In addition, outer membrane protein(OMP) of the isolates were extracted to determine its properties and immunogenicity in both mice and piglets. Of 3,395 slaughter pigs, pleuropneumonia was observed in 425 pigs(10.6%). A. pleuropneumoniae was isolated from 22 pigs(5.2%) out of 425 pigs with pneumonic lesions. The biochemical properties of all isolates were same as those of reference A. pleuropneumoniae strain. Among 22 isolates, 9, 1 and 12 isolates were serovar 2, 3 and 5, respectively. The results of antimicrobial susceptibility test revealed that the isolates showed high susceptibility to ciprofloxacin and cephalothin, moderate susceptibility to amikacin, gentamicin, kanamycin and streptomycin, and low susceptibility to erythromycin, tylosin and sulfadimethoxin. The isolates were varied in pathogenicity to mice. Median lethal dose of LE9402(serovar 2) and LE9511(serovar 5) were 9.2×10^7CFU and 2.8×10^7CFU, respectively. Specific pneumonic lesions were observed from the infected mice with clinical signs. Bacteria recovery rate was high in the lung, but low in heart blood and tracheas. Serovar 2 was found to be more pathogenic than serovar 5 in guinea pig. Mortality on guinea pigs inoculated with serovar 2(5.4×10^8 - 5.4×10^6CFU) abd serovar 5(2.8×10^8 - 2.8×10^6CFU) was 20-40% and 40-80%, respectively. A severe hemorrhagic lesions and focal pneumonic lesions were observed from dead guinea pigs. Bacteria recovery rate was relatively higher in the lung than that of other organs. In the SDS-PAGE analysis, OMP-enriched fractions of both isolates and reference strains contain common peptide bands equivalent to molecular weight of 17, 27, 42, 52 and 95Kd. In addition to common peptide bands, the bands which are specific to each isolate were also observed. The profiles of Sephadex G25 fractions showed 3 major peaks. The common peptide bands which were observed by SDS-PAGE of the crude OMPs were found i the peaks 1 and 2. The OMPs extracted from serovar 2(LE9402) and serovar 5(LE9511) provided high level of protection in mice(70-80%) and pigs(100%). All animals inoculated with OMPs were seroconverted, showing micro-agglutination titer of 640 to 1280.

SGML을 이용한 제안서, 보고서 관리시스템 기술 개발

전병현,한치근,이상훈 경희대학교 산학협력기술연구원 1997 산학협력기술연구논문집 Vol.3 No.-

We designed an SGML-Based Proposal and Report Management System in this paper. In this system, SGML files are stored in a database and can be searched using keywords. Hence, the documents can be handled efficiently. The relational database structure is recommended for the system and also a hybrid approach is discussed for multimedia information in the text. Functions for each module of the system are defined and conceptual and practical design issues are provided.

스코폴라민의 흰쥐 피부투과에 대한 투과촉진제들의 영향

정재영,감성훈,김건남,지상철,박은석 한국약제학회 2003 Journal of Pharmaceutical Investigation Vol.33 No.2

The transdermal therapeutic system (TTS) of scopolamine has various advantages over its oral dosage forms. The ideal scopolamine TTS requires high skin permeation rate in short time after it is applied on the skin. In order to increase the initial skin permeation rate of scopolamine from TTS, various permeation enhancers were employed. Enhancers employed were fatty acids(oleic and linolenic acids), cyclic monoterpenes(menthol, camphor, cineole and limonene) and others(isopropyl myristate, sodium lauryl sulfate and glyceryl monostearate). The concentration of enhancers in the base were fixed to 5% (w/w). While fatty acids had little enhancing effect on the skin permeation of scopolamine, cyclic monoterpenes, isopropyl myristate and sodium lauryl sulfate resulted in 1.5∼2.36-fold higher skin permeation rate of the drug compared to the control. However, lag time was not affected by enhancers studied.

톨루엔 디이소시아네이트 폭로 근로자들의 생물학적 모니터링

안연순,노재훈,김치년,박윤정,정상혁 大韓産業醫學會 1995 대한직업환경의학회지 Vol.7 No.2

Toluene diisocyanate(TDI) is widely used in the production of flexible polyurethane foams, as well as in the formulation of polyurethane paints and coatings. The commercial material is generally a mixture of 2,4- and 2, 6-TDI, the predominant mix being 80% 2,4 and 20% 2,6-TDI. The 2,4-isomer is considerably more reactive than the 2,6-TDI at ambient temperatures due to steric factors involving the positions of the isocyanate groups relative to the ring methyl group. Because of this difference in the reactivities of the isomers, it seemed probable that there might be an increase in the amount of 2,6-TDI offgased relative to the 2,4-isomer. Therefore a relative enrichment of the 2,6-TDI has been found in industrial atmospheres. Toluene diamines, which are metabolites of TDI, in urine have a linear relation with exposure to TDI, so that urianry TDA could be used as a biological index of the exposure to TDI. This study was conducted to investigate the distribution of TDI isomer in industrial atmospheres and to propose proper biological monitoring methods by identifying the relationships between the environmental TDI exposure and concentration of TDA in urine. Concentrations of 2, 4-TDI and 2, 6-TDI in air were 4.38㎍/㎥ and 25.43㎍/㎥, respectively. The Threshold Limited Value of 40㎍/㎥ was exceeded for the 2, 6-TDI in about 46.8%(22 samples) of the samples, while the 2, 4-TDI was not at all exceeded. The ratio between 2, 4-TDI and 2, 6-TDI varied in air samples in the range of 2.4%:97.6%-51.0%:49.0%. There was an enrichment of 2, 6-TDI in air relative to the 2, 4-TDI. Concentrations of 2, 4-TDA and 2, 6-TDA in urine were 1.31㎍/g creatinine and 4.16㎍/g creatinine, respectively. The ratio between 2, 4-TDA and 2, 6-TDA varied in urine samples in the range of 1.4%:98.6%-99.9%:0.1%. There was an enrichment of 2, 6-TDA in urine relative to the 2, 4-TDA. No relation between the concerations of TDA isomer in urine and concerations of TDI isomer in air was found. Above results of this study, workers were more exposed to the 2, 6-TDI relative to the 2, 4-TDI in industrial atmospheres. Therefore, the establishment of TLV for 2, 6-TDI should be considered. Also, the further studies on biological monitorigs of workers exposed to TDI should be continued.

복망-척수 이전술을 이용한 비외상성 경추 및 흉추 협착성 척수병증의 치료 경험

김영수,조용은,지훈상 대한신경외과학회 1993 Journal of Korean neurosurgical society Vol.22 No.2

Stenotic myelopathy due to ossification of posterior longitudinal ligament or degenerative spondylosis compresses the spinal cord and produces pain, motor weakness, sensory change. spasticity by several factors such as direct compression, vascular factor, mechanical factors. Chronic compression of spinal cord causes a ischemic change of spinal cord and cord atrophy. In this condition, only decompression of cord with wide decompressive laminectomy or expansive laminoplasty initially can expect mild improvement of clinical conditions of cord compression, but it cannot improve the irreversible ischemic change or atrophy of cord Omentum in peritoneal cavity has good blood supply and has lipid angiogenic factors proven by experimental study. Using these characteristics omentum transposition to spinal cord in chronic spinal cord injured patients have been tried. Authors tried the omentum-spinal transposition after wide decompressive laminectomy in three cases of severe nontraumatic spinal stenotic myelopathy and experienced the marked clinical improvement in one case of them. Operative thechniques were introduced and literatures were reviewed.