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Sangphil Park,고원건,P.S. Keshava Murthy,Saemi Park,Y. Murali Mohan 한국공업화학회 2011 Journal of Industrial and Engineering Chemistry Vol.17 No.2
In this investigation, we prepared semi-interpenetrating network (IPN) hydrogels composed of pluronic and poly(acrylamide), using free radical polymerization with a redox initiator system in the presence of N,N0-methylenebisacrylamide. The hydrogels served as templates for producing highly stable and uniformly distributed silver nanoparticles via in situ reduction of silver nitrate (AgNO_3) using sodium borohydride (NaBH_4) as reducing agent. We confirmed the formation of silver nanoparticles using ultraviolet visible (UV–vis) spectroscopy and X-ray diffraction (XRD). Stability and morphology of the nanoparticles was examined using thermogravimetric analysis (TGA), scanning electron microscopy (SEM) and transmission electron microscopy (TEM). Finally, we demonstrated the presence of antibacterial activity in the developed hydrogel–silver nanocomposite.
급성골수구성백혈병에서 재발의 첫 임상증상으로 나타난 시신경유두 침범의 1예
박새미,박성규,박태관,Saemi Park,Seong-Kyu Park,Tae Kwann Park 대한안과학회 2011 대한안과학회지 Vol.52 No.2
Purpose: To present a case of leukemic infiltration of the optic nerve head as the initial manifestation of leukemic relapse. Case summary: A 65-year-old woman was diagnosed with acute myeloid leukemia. Complete remission was achieved after 4 complete courses of chemotherapy. She complained of a sudden decrease in visual acuity in her left eye. Fundus examination showed severe optic disc edema with peripapillary hemorrhage and serous retinal detachment. Visual acuity and fundus continued to aggravate and high-dose intravenous steroid therapy was instituted. Visual acuity and fundus deteriorated more after treatment. Brain magnetic resonance imaging and CSF study were normal but intrathecal chemotherapy and focal irradiation were performed on account of the suspected CNS involvement of leukemia. Morphologic improvement in the retinal structure was achieved, however, optic atrophy remained and her vision did not recover. Conclusions: The present case shows the involvement of the optic nerve head as the initial isolated manifestation for the relapse in a patient with complete remission. CNS involvement is rare in acute myeloid leukemia and in particular, the optic nerve is rarely reported as the initial isolated presentation for the relapse. Moreover, the disease progression relatively aggravated after treatment. In the atypical aspects of leukemic relapse, the present case was noticeable. J Korean Ophthalmol Soc 2011;52(2):250-254