http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Multigigabit CMOS limiting amplifier and VCSEL driver arrays for parallel optical interconnects
Kang, Sae-Kyoung,Lee, Tae-Woo,Park, Hyo-Hoon Wiley Subscription Services, Inc., A Wiley Company 2006 MICROWAVE AND OPTICAL TECHNOLOGY LETTERS - Vol.48 No.8
<P>Limiting amplifier and VCSEL driver arrays for parallel optical interconnects operating at 8 Gb/s are presented, which are designed and fabricated in a Si-based 0.18-μm CMOS technology for the single chip integration with low-power consumption. The limiting amplifier array showed a differential gain of 26 dB, a −3-dB bandwidth of 6.8 GHz, and a crosstalk of −32 dB between channels. For the VCSEL driver array, it showed a differential gain of 25 dB, a −3-dB bandwidth of 6.3 GHz, and crosstalk of −26 dB between channels. The power dissipation per channel of the limiting amplifier and the VCSEL driver are 45 and 120 mW, respectively. © 2006 Wiley Periodicals, Inc. Microwave Opt Technol Lett 48: 1656–1659, 2006; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.21691</P>
Miniaturised 43 Gbit/s ROSA module using TO-can package for optical transceivers
Sae-Kyoung Kang,Joon Ki Lee,Joon Young Huh,KwangJoon Kim,Jong Hyun Lee IET 2014 Electronics letters Vol.50 No.7
<P>A 43 Gbit/s receiver optical subassembly (ROSA) module using a compact transistor outline-can (TO-can) package has been developed and successfully demonstrated at transmission over a 2 km single-mode fibre. The electrical interface of the ROSA is made of an impedance-matched flexible printed circuit board (FPCB) which is orthogonally connected to the TO-can package. The measured 3 dB optical-to-electrical bandwidth is ~31.5 GHz and the receiver sensitivity is <;-8.4 dBm at an extinction ratio of 8.2 dB and a bit error rate of 10<SUP>-12</SUP>.</P>
Sae-Kyoung Kang,고제수,Dong-Soo Lee,Hyunwoo Cho 한국전자통신연구원 2008 ETRI Journal Vol.30 No.2
In this paper, we demonstrate an electrically bandlimited carrier-suppressed return-to-zero (EB-CSRZ) signal generator operating up to a 10 Gbps data rate comprising a single-stage Mach-Zehnder modulator and a wideband signal mixer. The wideband signal mixer comprises inverter stages, a mixing stage, and a gain amplifier. It is implemented by using a 0.13 μm CMOS technology. Its transmission response shows a frequency range from DC to 6.4 GHz, and the isolation response between data and clock signals is about 21 dB at 6.4 GHz. Experimental results show optical spectral narrowing due to incorporating an electrical band-limiting filter and some waveform distortion due to bandwidth limitation by the filter. At 10 Gbps transmission, the chromatic dispersion tolerance of the EB-CSRZ signal is better than that of NRZ-modulated signal in single-mode fiber.
Kang, Seung-Gul,Na, Kyoung-Sae,Lee, Heon-Jeong,Chee, Ik-Seung,Lee, Kwanghun,Lee, Jonghun Wolters Kluwer Health, Inc. All rights reserved. 2015 JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY Vol.35 No.2
ABSTRACT: The aim of this study was to identify the association between the rs1079597 and rs1800497 genetic polymorphisms of the gene encoding the dopamine D2 receptor (DRD2) protein and the treatment response to the selective dopamine receptor antagonist amisulpride. After 6 weeks of treatment with amisulpride, 125 schizophrenia patients were interviewed based on the Positive and Negative Syndrome Scale and the Clinical Global Impression-Severity Scale. Genotyping for rs1079597 and rs1800497 was performed using the TaqMan single nucleotide polymorphism genotyping assay. There were significant differences in the genotype frequency of the recessive model (&khgr; = 5.73, P = 0.017) and allele frequency (&khgr; = 5.16, P = 0.023) of rs1079597 between the responders and nonresponders based on the Positive and Negative Syndrome Scale negative symptoms scores. There was no significant finding in this regard for the rs1800497 polymorphism. The T-C and C-C haplotype of rs1079597-rs1800497 were associated with the negative symptom treatment response to amisulpride after permutation test. To the best of our knowledge, this is the first report of the positive finding in the association study between rs1079597 polymorphism and the treatment response to amisulpride in schizophrenic patients. A larger scale study involving more single nucleotide polymorphisms of DRD2 will progress the research into the pharmacogenetics of the treatment response to amisulpride.
Kang, Seung-Gul,Chee, Ik-Seung,Chang, Hun Soo,Na, Kyoung-Sae,Lee, Kwanghun,Lee, Jonghun Elsevier 2017 Neuroscience Letters Vol.661 No.-
<P><B>Abstract</B></P> <P>Synaptosomal-associated protein 25kDa (<I>SNAP25</I>) is a promising candidate gene related to the treatment response to antipsychotics. Thus, the present study investigated the associations between polymorphisms of <I>SNAP25</I> and the treatment response to amisulpride in patients with schizophrenia. This study enrolled 154 schizophrenic patients from six university hospitals in South Korea. All patients were assessed with the Positive and Negative Syndrome Scale (PANSS) and the Clinical Global Impression-Severity (CGI-S) scale at baseline and week 6 of treatment. Additionally, 101 subjects were genotyped for the <I>rs</I>8636 and <I>rs</I>3746544 single nucleotide polymorphisms (SNPs) of <I>SNAP25</I>. The genotype frequencies of <I>rs</I>8636 SNP significantly differed between responders and non-responders, measured by PANSS total score, in additive, recessive, and overdominant models. These findings suggest that <I>SNAP25</I> might be a useful marker for predicting the response to antipsychotics. Future studies should include a larger number of subjects, a comprehensive array of <I>SNAP25</I> SNPs, and functional analyses.</P> <P><B>Highlights</B></P> <P> <UL> <LI> We investigated the genetic association between <I>SNAP25</I> and response to amisulpride. </LI> <LI> Genotype frequencies significantly differed between responders and non-responders. </LI> <LI> <I>SNAP25</I> might be a useful marker for predicting the response to antipsychotics. </LI> </UL> </P>