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S. Al-Bahar,J. Chakkamalayath,A. Joseph,S. Al-Otaibi,M. Abdulsalam 대한토목학회 2018 KSCE JOURNAL OF CIVIL ENGINEERING Vol.22 No.4
The current trend in concrete science and technology is to characterize the cementitious materials in multiscales so that the optimalperformance of concrete can be achieved with the minimal use of cement as well as sustainable materials. It has been realized that thenew properties of many materials are discovered when examined at nanoscale. Nanoindentation test has been adopted as a techniqueto examine the nanomechanical properties of cementitious materials leading to an improvement of their macro-mechanicalperformance in terms of strength development, tailoring of desired properties, and durability. The evidence of an experimentalinvestigation to evaluate the influence of micro- and nanocement additives on the nanomechanical properties and the surfacemorphology of the hydrated cement paste is presented in this paper. The effect of additives on the compressive strength of binary andternary blended cement paste was also examined. It could be concluded from these studies that the effect of the additives on theproperties of cement paste matrix at macroscale, microscale, and nanoscale can be correlated, and mixes can be designed for theoptimal performance by multiscale investigation.
The impact of omeprazole on mycophenolate pharmacokinetics in kidney transplant recipients
( Mohamed S. Abdelhalim ),( Ahmed S. Kenawy ),( Heba H. El Demellawy ),( Amany A. Azouz ),( Sarah S. Alghanem ),( Torki Al-otaibi ),( Osama Gheith ),( Mohamed Abd Elmonem ),( Mohammed K. Afifi ),( Rag 대한신장학회 2020 Kidney Research and Clinical Practice Vol.39 No.4
Background: The absorption rates of mycophenolate mofetil (MMF) and enteric-coated mycophenolate sodium (ECMPS) may be influenced by the concomitant use of omeprazole. Methods: One hundred kidney transplant patients were recruited during their outpatient visits, including 50 on MMF and 50 on EC-MPS. At the clinic, a predose mycophenolic acid (MPA) sample (C0) was collected; subsequently, the participants received the proton-pump inhibitor omeprazole along with either MMF or EC-MPS. Two more blood samples were collected at 1.5 and 3.5 hours and used to estimate an area under the curve (AUC) from zero to 12 hours [AUC (0-12)]. Results: The mean number of months after transplant was 92 months. The median AUC (0-12) and C0 results were 62.2 mg·h/L and 2.0 mg/L for the MMF group and 71.9 mg·h/L and 1.8 mg/L for the EC-MPS group (P = 0.160 and 0.225, respectively). Interestingly, 54% of the MMF group and 62% of the EC-MPS group showed AUCs above the target values. The correlation between MPA C0 and the predicted AUC was poor in both groups. Conclusion: Omeprazole can be safely co-administered with either MMF or EC-MPS, as it did not compromise the MPA exposure. Unexpectedly, however, a high percentage of patients presented MPA AUCs exceeding the target value, highlighting the importance of periodically assessing MPA level.
Ali S. Omrani,Mohammed F. Al-Otaibi,Souad M. Al-Ateah,Fahad M. Al-Onazi,Kamran Baig,Noura A. El-Khizzi,Ali M. Albarrak 대한감염학회 2014 Infection and Chemotherapy Vol.46 No.1
Background: GeneXpert MTB/RIF is a real-time PCR assay with established diagnostic performance in pulmonary and extra-pulmonaryforms of tuberculosis. The aim of this study was to assess the contribution of GeneXpert MTB/RIF assay to the management ofpatients with any form of active tuberculosis in a single large tertiary center in Saudi Arabia, with a special focus on the impact ontime to start of antituberculous therapy compared with Ziehl-Neelsen (ZN) smears and mycobacterial cultures. Materials and Methods: Clinical, radiological and laboratory records for all patients who were commenced on antituberculous therapybetween March 2011 and February 2013 were retrospectively reviewed. Results: A total of 140 patients were included, 38.6% of which had pulmonary tuberculosis. GeneXpert MTB/RIF was requested for only39.2% of patients and was the only reason for starting antituberculous therapy for only 12.1%. The median time to a positive GeneXpertMTB/RIF result was 0 days (IQR 3) compared with 0 day (IQR 1) for smear microscopy (P > 0.999) and 22 days (IQR 21) for mycobacterialcultures (P < 0.001). No patients discontinued antituberculous therapy because of a negative GeneXpert MTB/RIF result. Conclusions: In a setting wherein physicians are highly experienced in the diagnosis and treatment of tuberculosis, GeneXpertMTB/RIF was remarkably under-utilized and had only a limited impact on decisions related to starting or stopping antituberculoustherapy. Cost-effectiveness and clinical utility of routine testing of all smear-negative clinical samples submitted for tuberculosisinvestigations by GeneXpert MTB/RIF warrant further study.
Suitability of Camel Milk for Making Yogurt
Najeeb S. Al-Zoreky,Mutlag M. Al-Otaibi 한국식품과학회 2015 Food Science and Biotechnology Vol.24 No.2
Yogurt was produced using camel milk (CAM). Stabilizers (CMC, pectin, gum acacia, or alginate) were added at 0.6% to improve the texture and acceptability of CAM yogurt. The pH (4.59-4.63) and titratable acidity (0.71-0.87 %) of the CAM yogurt product were different from cow milk control yogurt. CAM yogurt contained 10.6 mg/mL of lactic acid based on HPLC. The separated whey (33.5%) of CAM yogurt with alginate was higher than for control cow milk yogurt (23.8%), indicating a weaker water holding capacity. Stabilizers did not improve the consistency and coagulum of CAM yogurt, compared with bovine milk yogurt.
Helping People with Visual Disability Using AI
Naif Al Otaibi,Tariq S Almurayziq International Journal of Computer ScienceNetwork S 2024 International journal of computer science and netw Vol.24 No.1
Artificial Intelligence (AI) technology has evolved rapidly in recent years and is used in everything from banking to email management to surgery, but without the help of the visible, most of the fun features of the Internet include visual impairment. It benefits people with disabilities. The main purpose of this study is to find ways to help people with visual impairments using AI technology. A visually impaired request is made for the visually impaired. For example, when a message arrives that the program will notify you by voice (reads the sender's name, read the message, and replies to it if necessary), this is a special program installed on your mobile phone. This program uses a customized algorithm developed in Python to convert written text to voice, read text, and convert voice to written text on a message when a visually impaired person wants to respond. Then it sends the response in the form of a text message. Therefore, the research should lead to programs for people with visual impairments. This program makes mobile phones easier and more comfortable to use and makes the daily life easier for visual impairments.