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      • Complex Vector Analysis and Suppression of Parallel Vibration of Distributed Power Grid Connected Converter

        Rui Guo,Cunxu Wang,Shu Liu,Xin Guan,Wei Gao,Shuaijie Wang,Chuan Chen 보안공학연구지원센터 2016 International Journal of Grid and Distributed Comp Vol.9 No.10

        With the continuous expansion of the scale of distributed power generation,multi grid connected converters often prone to oscillation problems when parallel operation.In this paper,we study the equivalent circuit of parallel connection of multi grid connected converters , system response characteristics of voltage source and in-depth analysis of the causes of the parallel oscillation of the converters.This paper analyzes converter’s parallel complex vector model by complex vector and comes to a conclusion that power grid voltage feed-forward will produce strong coupling between converter so that cause oscillation parallel converters. In view of the above problems and the flow of the converter starting or the voltage fluctuation of the grid, we design a low feed forward method, that is to make the fundamental and the main sub components of the grid voltage forward without delay and for the relative high frequency components, the filter technology is used to attenuate, so as to achieve the maximum elimination of the feed-forward coupling between the converter, to prevent the occurrence of system oscillation. In order to verify the use of this paper, the theory of the parallel converter is applied in the field of MW level wind field. The experimental results prove the correctness of the theory.

      • Morphological Factors and Cardiac Doses in Whole Breast Radiation for Left-sided Breast Cancer

        Guan, Hui,Dong, Yuan-Li,Ding, Li-Jie,Zhang, Zi-Cheng,Huang, Wei,Liu, Cheng-Xin,Fu, Cheng-Rui,Zhu, Jian,Li, Hong-Sheng,Li, Miao-Miao,Li, Bao-Sheng Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.7

        Background: To investigate the impact of the breast size, shape, maximum heart depth (MDH), and chest wall hypotenuse (the distance connecting middle point of the sternum and the length of lung draw on the selected transverse CT slice) on the volumetric dose to heart with whole breast irradiation (WBI) of left-sided breast cancer patients. Materials and Methods: Fifty-three patients with left-sided breast cancer undergoing adjuvant intensity-modulated radiotherapy (IMRT) were enrolled in the study. The primary breast size and shape, MHD and DCWH (chest wall hypotenuse) were contoured on radiotherapy (RT) planning CT slices. The dose data of hearts were obtained from the dose-volume histograms (DVHs). Data were analyzed by one-way analysis of variance (ANOVA), Student's t-test and linear regression analysis. Results: Breast size was independent of heart dose, whereas breast shape, MHD and DCWH were correlated with heart dose. The shapes of breasts were divided into four types, as the flap type, hemisphere type, cone type and pendulous type with heart mean dose being $491.8{\pm}234.6cGy$, $752.7{\pm}219.0cGy$, $620.2{\pm}275.7cGy$, and $666.1{\pm}238.0cGy$, respectively. The flap type of breasts shows a strong statistically reduction in heart dose, compared to others (p=0.008 for V30 of heart). DCWH and MHD were found to be the most important parameters correlating with heart dose in WBI. Conclusions: More attention should be paid to the heart dose of non-flap type patients. The MHD was found to be the most important parameter to correlate with heart dose in tangential WBI, closely followed by the DCWH, which could help radiation oncologists and physicsts evaluate heart dose and design RT plan in advance.

      • Cellular Mechanisms of a New Pyrazinone Compound that Induces Apoptosis in SKOV-3 Cells

        Wang, Guan,Jiang, Meng-Ying,Meng, Ying,Song, Hong-Rui,Shi, Wei Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.2

        We screened a small molecular library that was designed and independently synthesized in vitro and found a new drug (MY-03-01) that is active against ovarian cancer. We established that MY-03-01 effectively inhibited SKOV-3 cell survival in a dose-dependent manner, based on cell viability rates, and that it not only induced SKOV-3 apoptosis by itself, but also did so synergistically with paclitaxel. Secondly, when MY-03-01 was applied at $40{\mu}M$, its hemolytic activity was less than 10%, compared with the control, and there was almost no damage to nor mal cells at this concentration. In addition, we used DAPI staining and flow cytometry to show that MY-03-01 could significantly induce apoptosis of SKOV-3 cells. Finally, we found that MY-03-01 likely induced SKOV-3 apoptosis by activating caspase3 and caspase9 through the mitochondrial pathway.

      • In-situ photocrosslinked hydroxide conductive membranes based on photosensitive poly(arylene ether sulfone) block copolymers for anion exchange membrane fuel cells

        He, Rui,Wen, Pushan,Zhang, Hai-Ning,Guan, Shumeng,Xie, Guangyong,Li, Li-Zhong,Lee, Myong-Hoon,Li, Xiang-Dan Elsevier 2018 Journal of membrane science Vol.556 No.-

        <P><B>Abstract</B></P> <P>A series of photocrosslinkable multi-block poly(arylene ether sulfone) copolymers containing various block lengths of hydrophilic segments were synthesized. For comparison, a series of random poly(arylene ether) copolymers were also synthesized. The anion exchange membranes(AEMs) were fabricated and in-situ photocrosslinking was carried out by UV irradiation in a swollen state. The microphase-separated morphologies of the multi-block membranes were characterized by SAXS and TEM experiments, and the membrane properties were investigated by measuring ion exchange capacity (IEC), water uptake, water swelling ratio, ionic conductivity, methanol permeability and alkaline stability. IECs and water uptakes of the crosslinked multi-block membranes were in the range of 1.11–1.42 meq g<SUP>−1</SUP> and 14.36–31.01% at 20 °C, respectively. The hydroxide conductivity was in the range of 11.38–25.00 mS cm<SUP>−1</SUP> at 20 °C, and showed a maximum value of 178.77 mS cm<SUP>−1</SUP> at 100 °C. The multi-block membranes exhibited low methanol permeability (2.75 × 10<SUP>−7</SUP> cm<SUP>2</SUP> s<SUP>−1</SUP>) at room temperature, which is one order of magnitude lower than that of Nafion® 117 (23.8 × 10<SUP>−7</SUP> cm<SUP>2</SUP> s<SUP>−1</SUP>). The crosslinked membranes showed excellent dimensional stability and alkaline stability with only a slight decrease in ionic conductivity. All the multi-block membranes showed superior properties compared to their corresponding random copolymers.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Multi-block poly(arylene ether sulfone) copolymers were synthesized for AEMs. </LI> <LI> <I>In-situ</I> photo-crosslinking was carried out by UV irradiation in hydrated states. </LI> <LI> The block copolymers exhibited hydrophilic/hydrophobic phase separated morphology. </LI> <LI> The block copolymers showed superior properties compare to the random copolymers. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

      • KCI등재

        Research on intelligent tool condition monitoring based on data-driven: a review

        Yaonan Cheng,Rui Guan,Yingbo Jin,Xiaoyu Gai,Mengda Lu,Ya Ding 대한기계학회 2023 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.37 No.7

        The tool condition monitoring (TCM) can sense the real-time conditions of the tool to a large extent and warn the tool failure as early as possible. It can effectively improve processing efficiency, reduce production cost, and ensure production safety. With the rise of artificial intelligence technology, whether digital images obtained based on direct method or physical signals obtained through sensors by the indirect method can be regarded as valuable data. Using the artificial intelligence method to extract and identify the effective features in the data, mining the relationship between the tool wear or breakage and data is the key technology and difficulty of the intelligent tool condition monitoring. In this paper, the data representing tool wear or breakage characteristics are divided into image data and signal data. Moreover, the way to obtain high-quality data through image acquisition technology and multi-sensor fusion technology is discussed. Then the key principles and methods of feature extraction and decision making in TCM are studied. Finally, the future research direction is prospected based on the application of tool condition monitoring.

      • Design and Research on the Special System for High Efficient Manufacturing of Blisk Based on UG

        Yaonan Cheng,Rui Guan,Diange Zuo,Tianqi Chen,Li Liu 보안공학연구지원센터 2016 International Journal of Hybrid Information Techno Vol.9 No.10

        As one of the most important parts of aeroengine, blisk has complex structure and its material is titanium alloy hard to machine. It results in some difficulties in modeling and NC programming. In this paper, from the perspective of application, the secondary development technology of UG/Open Grip is used to design and develop the CAD/CAM module of blisk after analyzing structure feature and milling process of blisk. Firstly, it completes parametric modeling of blisk by establishing CAD module through the optimization of the original data points in NUBRS curve fitting and node interpolation technology; secondly, the inner and outer tolerance algorithm are applied to calculate the cutting step, and the row spacing is determined based on constant scallop height. Besides, tool axis vector is defined. All of these things are done to complete the establishment of the CAM module and realize trajectory planning of semi-finish machining of the blisk. It greatly improves the efficiency of programming and machining in blisks; finally, the module of blisk designed is used to model and program in the machining experiments in five axis machining center to verify correctness and reliability of the system. The results show that this module greatly improves manufacturing efficiency of blisk.

      • SCIESCOPUSKCI등재

        Effects of American Ginseng Cultivation on Bacterial Community Structure and Responses of Soil Nutrients in Different Ecological Niches

        ( Fan Chang ),( Fengan Jia ),( Rui Lv ),( Min Guan ),( Qingan Jia ),( Yan Sun ),( Zhi Li ) 한국미생물생명공학회 2022 Journal of microbiology and biotechnology Vol.32 No.4

        American ginseng (Panax quinquefolium L.) is a perennial herbaceous plant widely cultivated in China, Korea, the United States, and Japan due to its multifunctional properties. In northwest China, transplanting after 2-3 years has become the main mode of artificial cultivation of American ginseng. However, the effects of the cultivation process on the chemical properties of the soil and bacterial community remain poorly understood. Hence, in the present study, high-throughput sequencing and soil chemical analyses were applied to investigate the differences between bacterial communities and nutrition driver factors in the soil during the cultivation of American ginseng. The responses of soil nutrition in different ecological niches were also determined with the results indicating that the cultivation of American ginseng significantly increased the soluble nutrients in the soil. Moreover, the bacterial diversity fluctuated with cultivation years, and 4-year-old ginseng roots had low bacterial diversity and evenness. In the first two years of cultivation, the bacterial community was more sensitive to soil nutrition compared to the last two years. Proteobacteria, Actinobacteria, Gemmatimonadetes, Acidobacteria, Firmicutes, and Bacteroidetes dominated the bacterial community regardless of the cultivation year and ecological niche. With the increase of cultivation years, the assembly of bacterial communities changed from stochastic to deterministic processes. The high abundance of Sphingobium, Novosphingobium, and Rhizorhabdus enriched in 4-years-old ginseng roots was mainly associated with variations in the available potassium (AK), total phosphorus (TP), total potassium (TK), and organic matter (OM).

      • SCIESCOPUSKCI등재
      • KCI등재

        Association Study of Polymorphisms in Neuronal Nicotinic Acetylcholine Receptor Subunit Genes With Schizophrenia in the Han Chinese Population

        Yuan-yuan Li,Rui-jie Geng,Shun-ying Yu,Guan-jun Li,Zhou-ye Wang,Hua-fang Li 대한신경정신의학회 2021 PSYCHIATRY INVESTIGATION Vol.18 No.10

        Objective To investigate the relation between nicotinic acetylcholine receptor subunit (nAChR) genes and schizophrenia, and the relation between tag single nucleotide polymorphism (rs1317286, rs1044396, rs6494212, rs16969968, and rs684513) and schizophrenia in Han Chinese people. Methods The protein-protein interaction (PPI) network among nAChR protein and 350 proteins encoded by schizophrenia-related susceptibility genes was constructed through the String database to explore whether nAChR genes were associated with schizophrenia in these known databases. Then, five single nucleotide polymorphisms (SNPs) of CHRNA3 (rs1317286), CHRNA4 (rs1044396), CHRNA7 (rs6494212), and CHRNA5 (rs16969968, rs684513) were analyzed in a sample of 1,035 schizophrenic patients and 816 healthy controls. The interaction between the markers was analyzed using multifactor dimensionality reduction (MDR) software. Power analysis was performed using the Quanto program. Results There are no significant differences in genotype or allele distribution were identified between the patients and controls (p>0.05). The haplotypes constructed by four markers rs1317286, rs6494212, rs16969968, and rs684513 were not associated with schizophrenia either. However, a significant association between models made of rs1317286, rs1044396, rs6494212, and rs684513 and schizophrenia was revealed in interaction analysis (p<0.05). Conclusion The nAChR protein may have effects on the development of schizophrenia through the interaction with proteins encoded by schizophrenia-related susceptibility genes, but no relation was found between selected polymorphisms and schizophrenia in the collected Han Chinese people. However, interaction analysis suggested four-SNP model has an important effect on schizophrenia.

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