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      • KCI등재

        로그 데이터를 이용한 하둡기반 맞춤형 관광시스템

        Ding Ya,김강철(Kang Chul Kim) 한국전자통신학회 2018 한국전자통신학회 논문지 Vol.13 No.2

        인터넷 사용이 증가함에 따라 많은 사용자 행위가 로그 파일에 기록되고, 최근에 이들을 이용한 연구와 산업이 활성화되고 있다. 본 논문은 오픈 소스 기반 분산 컴퓨팅 플랫폼인 하둡을 사용하고, 로그 파일에 기록된 사용자 행위를 분석하여 맞춤형 관광 정보를 제공하는 시스템을 개발한다. 제안된 시스템은 사용자들이 검색한 웹사이트로부터 로그 파일을 얻기 위하여 구글의 Analytics를 사용하고, 하둡의 MapReduce를 사용하여 검색 항목을 추출하여 HDFS에 저장한다. Octopus 프로그램을 사용하여 여행안내 웹사이트로부터 여행관련 관광지나 도시에 대한 정보를 모으고, MapReduce를 사용하여 관광지의 특징을 추출한다. 그리고 관광지의 특징과 사용자 검색항목을 매칭하여 사용자에게 관광하고 싶은 맞춤형 도시를 제안한다. 본 논문에서는 매칭의 확률을 높이기 위하여 NBP(next bit permutation)알고리즘을 사용하여 검색항목과 관광지 특징을 재정렬하는 기법을 도입한다. 그리고 개발된 시스템의 효용성을 확인하기 위하여 39 명의 사용자에 대한 로그 데이터를 분석하여 맞춤형 관광도시를 제안한다. As the usage of internet is increasing, a lot of user behavior are written in a log file and the researches and industries using the log files are getting activated recently. This paper uses the Hadoop based on open source distributed computing platform and proposes a customized tourism system by analyzing user behaviors in the log files. The proposed system uses Google Analytics to get user’s log files from the website that users visit, and stores search terms extracted by MapReduce to HDFS. Also it gathers features about the sight-seeing places or cities which travelers want to tour from travel guide websites by Octopus application. It suggests the customized cities by matching the search terms and city features. NBP(next bit permutation) algorithm to rearrange the search terms and city features is used to increase the probability of matching. Some customized cities are suggested by analyzing log files for 39 users to show the performance of the proposed system.

      • KCI등재
      • KCI등재

        Dynamics of waste-to-energy incineration R&D collaboration networks: a social network analysis based on patent data

        Ding Ma,Yongsheng Yu,Si-shi Liu,Ya-rui Zhang 한국자원공학회 2017 Geosystem engineering Vol.20 No.2

        The municipal solid waste in China is increasing at an unprecedented pace due to the upgrading urbanization and improving living standard. The waste-to-energy (WTE) incineration technology offers a viable and potentially profitable technical solution to this booming phenomenon. The highly complex and systematic nature of WTE technologies have led to the emergence of WTE innovation network in the past decade. This study applies complex network theory as well as social network analysis to investigate the social network structure evolution of WTE technologies in terms of global network properties, major actors’ centrality and collaboration relationships. Based on the data-set covering joint filing patents pertaining to waste heat over the period 2006–2015, this study finds that the overall WTE innovation network exhibits the properties of scale-free network with minority organizations linking to abundant organizations. A large fraction of major actors represent the first-movers in the WTE research and still control the technological trajectories. The collaboration relationships have moved toward higher level of multidisciplinary and larger technological distance. Overall, the evolution of WTE innovation network features a young state of industry with high regime dependence. Finally, some suggestions are proposed to shed light on benign development of WTE innovation network.

      • KCI등재

        Effect of atorvastatin on dendritic cells of tubulointerstitium in diabetic rats

        ( Ya Fang Tu ),( Ru Han Jia ),( Guo Hua Ding ),( Ling Chen ) 한국생화학분자생물학회 (구 한국생화학회) 2010 BMB Reports Vol.43 No.3

        Inflammatory reactology has become increasingly important in diabetic kidney disease. In this study, we estabilished STZ-induced diabetic rat model to investigate whether dendritic cells (DCs) mediated tubulointerstitial damages, and whether the effects by DCs were mediated by P-selectin expression and can be inhibited by atorvastatin. The study demonstrated that there was an accumulation of DCs in diabetic rats mediated by P-selectin. It also showed the accumulation of DCs and expression of P-selectin was closely correlated with the degree of renal tubulointerstitial injury. These effects were markedly attenuated by atorvastatin. Thus, DCs play a role in tubulointerstitial damages, atorvasttin can prevent renal tubulointerstitium from damage by inhibiting the P-selectin expression and DCs migration. [BMB reports 2010; 43(3): 188-192]

      • KCI등재

        IL-13 R110Q, a Naturally Occurring IL-13 Polymorphism, Confers Enhanced Functional Activity in Cultured Human Bronchial Smooth Muscle Cells

        Ya-fang He,Li Hua,Yi-xiao Bao,Quan-hua Liu,Yi Chu,Ding-zhu Fang 대한천식알레르기학회 2013 Allergy, Asthma & Immunology Research Vol.5 No.6

        Purpose: Interleukin (IL)-13, a Th2-type cytokine, plays a pivotal role in the pathogenesis of asthma through its direct effects on airway smoothmuscles. A naturally occurring IL-13 polymorphism, R110Q, is strongly associated with increased total serum IgE levels and asthma. In the presentstudy, we aimed to determine whether the IL-13 R110Q variant would display different biochemical properties or altered functions in comparisonwith wild-type (WT) IL-13 in cultured human bronchial smooth muscle cells (hBSMCs). Methods: Culture supernatants and cell proteins were collectedfrom cultured hBSMCs that were treated with 50 ng/mL IL-13 or IL-13 R110Q for 24 h. Eotaxin released into hBSMC culture medium was determinedby ELISA. The expression levels of the high-affinity IgE receptor (FcεRI) α-chain, smooth muscle-specific actin alpha chain (α-SMA), smoothmuscle myosin heavy chain (SmMHC), and calreticulin in the cells were measured on Western blots. Results: Compared with WT IL-13, treatmentwith the IL-13 R110Q variant resulted in a significant increase in eotaxin release as well as significant, although modest, increases in the expressionlevels of α-SMA, SmMHC, calreticulin, and FcεRI α-chain. Conclusions: The results of the present study suggenst that the IL-13 R110Q variantmay enhance enhanced functional activities in hBSMCs.

      • KCI등재

        Novel miR-1958 Promotes Mycobacterium tuberculosis Survival in RAW264.7 Cells by Inhibiting Autophagy Via Atg5

        ( Shuqin Ding ),( Yuliang Qu ),( Shaoqi Yang ),( Ya’e Zhao ),( Guangxian Xu ) 한국미생물생명공학회(구 한국산업미생물학회) 2019 Journal of microbiology and biotechnology Vol.29 No.6

        Autophagy is crucial for immune defense against Mycobacterium tuberculosis (Mtb) infection. Mtb can evade host immune attack and survival within macrophages by manipulating the autophagic process. MicroRNAs (miRNAs) are small, non-coding RNAs that are involved in regulating vital genes during Mtb infection. The precise role of miRNAs in autophagy with the exits of Mtb remains largely unknown. In this study, we found miR-1958, a new miRNA that could regulate autophagy by interacting with 3'UTR of autophagy-related gene 5 (Atg5). In addition, Mtb infection triggered miR-1958 expression in RAW264.7 cells. What's more, miR- 1958 overexpression blocked autophagic flux by impairing the fusion of autophagosomes and lysosomes. Overexpression of miR-1958 reduced Atg5 expression and LC3 puncta while inhibition of miR-1958 brought an increase of Atg5 and LC3 puncta; the opposite results were observed in detection of p62. The survival of Mtb in RAW264.7 cells transfected with mimic of miR-1958 was enhanced. Taken together, our research demonstrated that a novel miR-1958 could inhibit autophagy by interacting with Atg5 and favored intracellular Mtb survival in RAW264.7 cells.

      • KCI등재

        Net micromineral requirements for maintenance and growth of ewe lambs at the latter fattening period

        Jin Ya Qian,Ding Na,Diao Xiao Gao,Yu Sheng Chen,Zhao Jun Xing,Zhang Jian Xin 아세아·태평양축산학회 2020 Animal Bioscience Vol.33 No.9

        Objective: The objective of this study was to investigate the net micromineral (Cu, Fe, Mn, Zn) requirements for maintenance and growth of Dorper×Jinzhong crossbred ewe lambs at their latter fattening period. Methods: Thirty 1/2 Dorper × 1/2 Jinzhong crossed F1 ewe lambs (35±0.5 kg of body weight [BW]) were used and divided into five groups in a randomized design for a comparative slaughter trial. At the beginning of the experiment, six lambs were randomly selected and slaughtered at 35 kg BW to determine their initial body composition. When their BWs reached 43 kg, another six lambs fed ad libitum were slaughtered to serve as an intermediate slaughter group. The retained eighteen lambs were randomly distributed into three groups and offered one type of feed at 100%, 65%, and 40% of the ad libitum intake. When the lambs fed ad libitum reached a BW of 50 kg, the three groups were slaughtered. The body composition (muscle, fat, bone, blood with viscera, skin, and wool) were weighted, ground, mixed, and subsampled for mineral content analysis. Results: The net maintenance requirements of Cu, Fe, Mn, and Zn were 0.017, 0.160, 0.004, and 0.067 mg/kg BW/d, respectively, and the net growth requirements per 100 grams of average daily gain ranged from 0.48 to 0.51 mg of Cu, 2.63 to 2.17 mg of Fe, 0.12 to 0.15 mg of Mn, and 2.07 to 2.00 mg of Zn, respectively, for Dorper × Jinzhong crossed ewes from 35 to 50 kg BW. Conclusion: Our results suggest that the micromineral requirements for both maintenance and growth of Dorper × Jinzhong crossbred ewe lambs were quite different from the recommendations of NRC (2007), except for Zn.

      • KCI등재

        THE MAGNETIC SEPARATION OF Nd - Fe - B POWDERS

        Li-Ya Cui,Da-Li Zheng,Jing-Han Zhu,Wei-Hong Zhao,Shu-Lin Ding 한국자기학회 1995 韓國磁氣學會誌 Vol.5 No.5

        The magnetic separation of Nd-Fe-B powders prepared by melt-spun and HDDR processes was investigated. The experiments show that the ununiform melt-spun powders can be separated into various standards by means of magnetic separation method. The magnetic powders with higher properties were obtained by the use of suitable separating field. For example, the properties of ununiform melt-spun powders are Br=7.95 kG, iHc=9.93 kOe and (BH)max=10.2 MGOe before separating. Through separating in different magnetic fields, the powders obtained with a separating field of 780 Oe has the optimum properties of Br=7.7 kG, iHc=11.0 kOe and (BH)max=15.3 MGOe. The magnetic properties of the HDDR magnetic powder are hardly separated by the magnetic separation method.

      • KCI등재

        Efficient Analysis of the Deformation and Fracture Properties of Nano-SiO2 Reinforced ABS/PMMA Composites

        Jin Ding,Dian Chen Li,Ya Hui Huang,Zhen Shan Fu 한국고분자학회 2022 폴리머 Vol.46 No.4

        This study investigated the damage mechanism of acrylonitrile-butadiene styrene (ABS)/poly(methyl methacrylate) (PMMA)/nano-SiO2 composites. The distortion and fracture behavior of ABS/PMMA/nano-SiO2 compositeswere predicted by developing the homogenization theory and the surface-based cohesive method. This model simulatedthe elementary action of elastoplastic damage in the matrix, the fracture for the nano-SiO2 reinforcement, and traction separation for interfaces. The experiment and morphology of the fracture section were validated by the modeling results. Thedamage mechanisms of ABS/PMMA/nano-SiO2 composites were researched with the numerical results, and the roles ofnano-SiO2 strength in the mechanical properties of ABS/PMMA blends were discussed in detail

      • KCI등재

        Metabolomic analysis of biochemical changes in the tissue and urine of proteoglycan-induced spondylitis in mice after treatment with moxibustion

        Xiao Xu,Ya-Nan Shi,Rong-Yun Wang,Cai-Yan Ding,Xiao Zhou,Yu-Fei Zhang,Zhi-Ling Sun,Zhi-Qin Sun,Qiu-Hua Sun 한국한의학연구원 2021 Integrative Medicine Research Vol.10 No.1

        Background: Moxibustion is widely used in East Asian countries to manage the symptom of rheumatic diseases. The aim of this study was to identify potential metabolic profiles of moxibustion on relieving ankylosing spondylitis (AS) mice through UHPLC-Q-TOF/MS metabolomic study. Methods: Thirty-two female Balb/c mice were randomized into healthy control (HC), AS model, moxibustion at acupuncture points (MA) in AS model, and moxibustion at non-acupuncture points (MNA) AS model groups. Moxibustion was administered daily at GV4, bilateral BL23 and bilateral ST36 acupuncture points for four weeks in the MA group. The overall health status, the thickness of hind paws and the tissue concentrations of IL-1β, PGE2, IL-6 and TNF-α were assessed. The UHPLC-Q-TOF/MS was used to explore the perturbations of endogenous metabolites in tissue and urine of AS model mice intervened by moxibustion. Results: Compared with the AS group, the overall health status was significantly improved after 4-week moxibustion intervention (p < 0.05). The results also showed that MA significantly reduced the levels of paw thickness and decreased the levels of four cytokines in the tissue (p < 0.01). Thirty-seven endogenous metabolites identified by the OPLS-DA were considered to be contributing to therapeutic effects of moxibustion. Moreover, metabolic pathway analysis further revealed that the identified metabolites were mainly involved in TCA cycle, Lipid metabolism, Amino Acid metabolism, Intestinal flora metabolism and Purine metabolism. Conclusions: UHPLC-Q-TOF/MS based metabolomics approach, as a novel and powerful tool, can help us to gain the insights into potential mechanisms of action of moxibustion for AS.

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