中文字辭重出之組合釋例

王仁鈞 단국대학교 중어중문학과 1980 中國文學報 Vol.- No.4

Evaluation of Renal Pathophysiological Processes Induced by an Iodinated Contrast Agent in a Diabetic Rabbit Model Using Intravoxel Incoherent Motion and Blood Oxygenation Level-Dependent Magnetic Resonance Imaging

Yongfang Wang,Xin Zhang,Bin Wang,Yang Xie,Yi Wang,Xuan Jiang,Rongjia Wang,Ke Ren 대한영상의학회 2019 Korean Journal of Radiology Vol.20 No.5

Objective: To examine the potential of intravoxel incoherent motion (IVIM) and blood oxygen level-dependent (BOLD) magnetic resonance imaging for detecting renal changes after iodinated contrast-induced acute kidney injury (CI-AKI) development in a diabetic rabbit model. Materials and Methods: Sixty-two rabbits were randomized into 2 groups: diabetic rabbits with the contrast agent (DCA) and healthy rabbits with the contrast agent (NCA). In each group, 6 rabbits underwent IVIM and BOLD imaging at 1 hour, 1 day, 2 days, 3 days, and 4 days after an iohexol injection while 5 rabbits were selected to undergo blood and histological examinations at these specific time points. Iohexol was administrated at a dose of 2.5 g I/kg of body weight. Further, the apparent transverse relaxation rate (R2*), average pure molecular diffusion coefficient (D), pseudo-diffusion coefficient (D*), and perfusion fraction (f) were calculated. Results: The D and f values of the renal cortex (CO) and outer medulla (OM) were significantly decreased compared to baseline values in the 2 groups 1 day after the iohexol injection (p < 0.05). A marked reduction in the D* values for both the CO and OM was also observed after 1 hour in each group (p < 0.05). In the OM, a persistent elevation of the R2* was detected for 4 days in the DCA group (p < 0.05). Histopathological changes were prominent, and the pathological features of CI-AKI aggravated in the DCA group until day 4. The D, f, and R2* values significantly correlated with the histological damage scores, hypoxiainducible transcription factor-1α expression scores, and serum creatinine levels. Conclusion: A combination of IVIM and BOLD imaging may serve as a noninvasive method for detecting and monitoring CIAKI in the early stages in the diabetic kidney.

A putative plastidial adenine nucleotide transporter, BRITTLE1-3, plays an essential role in regulating chloroplast development in rice (Oryza sativa L.)

Jia Lyu,Yihua Wang,Linglong Liu,Chunming Wang,Yulong Ren,Cheng Peng,Feng Liu,Yunlong Wang,Mei Niu,Di Wang,Ming Zheng,Kunneng Zhou,Shaolu Zhao,Fuqing Wu,Haiyang Wang,Jianmin Wan 한국식물학회 2017 Journal of Plant Biology Vol.60 No.5

Differentiation from proplastids into chloroplasts isa light- and energy-dependent process. How this process isregulated is still poorly understood at the molecular level. We herein report a new putative plastidial adenine nucleotidetransporter, BRITTLE1-3 (referred to as OsBT1-3), encoded bythe rice (Oryza sativa) White Stripe Leaf 2 (WSL2) gene. Loss of OsBT1-3 function results in defective chloroplastbiogenesis, severely reduced photosynthetic efficiency, andfinally a white stripe leaf phenotype in the first four leaves. The expression levels of genes related to chlorophyllbiosynthesis and photosynthesis are drastically reduced,accompanied with over accumulation of reactive oxygenspecies (ROS) in the wsl2 mutant. OsBT1-3 is targeted tothe chloroplasts and it expresses in almost all tissues inplants, especially in young leaves. OsBT1-3 consists of 419amino acids and exhibits features of all mitochondrialcarrier proteins, including a typical transmembrane-spanningdomain and a highly conserved sequence motif designatedas the ‘mitochondrial energy transfer signatures’. Phylogeneticanalysis shows that OsBT1-3 is a putative plastidialadenine nucleotide transporter and is most closely relatedto ZmBT1-2. Together, these observations suggest that thenew putative adenine nucleotide transporter, OsBT1-3,plays an essential role in regulating chloroplast biogenesisand maintenance of ROS homeostasis during rice seedlingde-etiolation.

Polymer Network Liquid Crystal (PNLC) Lenticular Microlens Array With No Surface Treatment

Wang, Xiahui,Ren, Hongwen,Wang, Qionghua IEEE 2016 Journal of display technology Vol.12 No.8

<P>A polymer network liquid crystal (PNLC) lenticular microlens array with no surface treatment is prepared. Before polymerization, the LC and diacrylate monomers are reoriented with gradient refractive index distribution by a fringing field. After polymerization, the oriented LC is stabilized by the polymer network. The prepared PNLC lenticular microlens array is optically anisotropic. Without surface treatment, the device fabrication is simplified, and it can present almost the same optical performance as the PNLC lenticular microlens with surface treatment. Integrating with a 90 twisted-nematic LC cell, the PNLC lenticular microlens array can be switched between a focusing state and non-focusing state. Such a PNLC lenticular microlens array has potential application in switchable 2D/3D displays.</P>

An Improved One Cycle Control for Active Power Filters under Non-Ideal Voltage Conditions

Wang, Lei,Ren, Chunguang,Yang, Yu,Han, Xiaoqing,Wang, Peng The Korean Institute of Power Electronics 2016 JOURNAL OF POWER ELECTRONICS Vol.16 No.6

The one cycle control (OCC) scheme for active power filters (APFs) has shown excellent harmonic suppression and implementation simplicity. However, its real world application is limited because the non-ideal supply voltage for APFs can influence its performance so that the source currents are still distorted after compensation. This paper proposes a modified one cycle control (MOCC) scheme to improve the performance of three-phase shunt APFs under non-ideal supply voltage conditions. In this paper a detailed mathematical derivation has been presented and the key control law of the MOCC has been developed for adaption to the non-ideal supply voltages, following the control philosophy of simplicity. A relatively simple sequence filter is introduced to extract the harmonic components of supply voltages. The modified scheme can be easily implemented. The proposed control strategy has excellent performance and a 5kVA APF hardware platform has been implemented to validate the feasibility and performance of the proposed strategy.

Research On Optimization In NC Bending Process Of Thin-walled Tube Based on Orthogonal Experiment

Ren Sheng-le,Wang Peng,Dai Ye 보안공학연구지원센터 2015 International Journal of Hybrid Information Techno Vol.8 No.1

In the process of research and development of tube bending forming technology, the way of improving the forming quality and establishing the optimization of forming process parameters has become an important problem that should be solved quickly. This text simulated the process of bend forming with the way of finite element, combined with the effects of geometric and physical parameters on the forming quality of bending pipe, taking the important parameters which are measurements of the pipe wall thickness variation as test indexes, made the virtual orthogonal experiment and gained the laws of the bending angle, relative bending radius, relative wall thickness, thrust, pipe friction coefficient between mode have effects on the forming quality of wall thinning rate and wall thickening. Through the comprehensive analysis and additional test, obtained the optimal parameters values, improved the accuracy of simulation and the optimization results of orthogonal test, improved the quality of tube bending forming.

Helicobacter pylori-Induced Progranulin Promotes the Progression of the Gastric Epithelial Cell Cycle by Regulating CDK4

Ren Zongjiao,Li Jiayi,Du Xianhong,Shi Wenjing,Guan Fulai,Wang Xiaochen,Wang Linjing,Wang Hongyan 한국미생물·생명공학회 2022 Journal of microbiology and biotechnology Vol.32 No.7

Helicobacter pylori, a group 1 carcinogen, colonizes the stomach and affects the development of stomach diseases. Progranulin (PGRN) is an autocrine growth factor that regulates multiple cellular processes and plays a tumorigenic role in many tissues. Nevertheless, the mechanism of action of PGRN in gastric cancer caused by H. pylori infection remains unclear. Here, we investigated the role of PGRN in cell cycle progression and the cell proliferation induced by H. pylori infection. We found that the increased PGRN was positively associated with CDK4 expression in gastric cancer tissue. PGRN was upregulated by H. pylori infection, thereby promoting cell proliferation, and that enhanced level of proliferation was reduced by PGRN inhibitor. CDK4, a target gene of PGRN, is a cyclin-dependent kinase that binds to cyclin D to promote cell cycle progression, which was upregulated by H. pylori infection. We also showed that knockdown of CDK4 reduced the higher cell cycle progression caused by upregulated PGRN. Moreover, when the PI3K/Akt signaling pathway (which is promoted by PGRN) was blocked, the upregulation of CDK4 mediated by PGRN was reduced. These results reveal the potential mechanism by which PGRN plays a major role through CDK4 in the pathological mechanism of H. pylori infection.

Time-varying physical parameter identification of shear type structures based on discrete wavelet transform

Wang, Chao,Ren, Wei-Xin,Wang, Zuo-Cai,Zhu, Hong-Ping Techno-Press 2014 Smart Structures and Systems, An International Jou Vol.14 No.5

This paper proposed a discrete wavelet transform based method for time-varying physical parameter identification of shear type structures. The time-varying physical parameters are dispersed and expanded at multi-scale as profile and detail signal using discrete wavelet basis. To reduce the number of unknown quantity, the wavelet coefficients that reflect the detail signal are ignored by setting as zero value. Consequently, the time-varying parameter can be approximately estimated only using the scale coefficients that reflect the profile signal, and the identification task is transformed to an equivalent time-invariant scale coefficient estimation. The time-invariant scale coefficients can be simply estimated using regular least-squares methods, and then the original time-varying physical parameters can be reconstructed by using the identified time-invariant scale coefficients. To reduce the influence of the ill-posed problem of equation resolving caused by noise, the Tikhonov regularization method instead of regular least-squares method is used in the paper to estimate the scale coefficients. A two-story shear type frame structure with time-varying stiffness and damping are simulated to validate the effectiveness and accuracy of the proposed method. It is demonstrated that the identified time-varying stiffness is with a good accuracy, while the identified damping is sensitive to noise.

A pressure-tolerant polymer microfluidic device fabricated by the simultaneous solidification-bonding method and flash chemistry application.

Ren, Wurong,Kim, Heejin,Lee, Hyune-Jea,Wang, Jun,Wang, Hao,Kim, Dong-Pyo Royal Society of Chemistry 2014 Lab on a chip Vol.14 No.21

<P>Pressure-tolerant polymer-glass microfluidic reactors with excellent bonding strength have been fabricated by the simultaneous solidification-bonding (SSB) method, in which a viscous and reactive matrix polymer was cast on the glass substrate with pre-patterned wax as a sacrificial template. Elaborate interfacial chemistry between the matrix polymer and the functionalized glass surface was designed to achieve simultaneous solidification and chemical bonding under UV or/and mild thermal conditions (<200 C with no pressure). Highly pressure-tolerant microchannels were obtained by complete removal of the liquid wax template at 80 C. Versatility was demonstrated by fabricating microreactors from various polymers with different interfacial chemistry, which were all stable at 1000 psi with the highest burst pressure of 2000 psi. In particular, the fluoropolymer-glass microreactor can withstand a burst pressure that is two orders of magnitude higher than that of the microchannel made by the conventional method. Finally, the polymer-glass microfluidic device was used for the synthesis of a natural product, tryptanthrin, by flash chemistry under high pressure induced conditions (synthetic yield: 90%, flow rate: 10.5 mL min(-1), reaction time: 14 ms). The transparent microfluidic device can be used as a useful platform for miniaturizing spectroscopic tools for chemical analysis studies under high pressure conditions.</P>

Patterning of CVD Diamond Films For MEMS Application

Wang, Xiaodong,Yang, Yirong,Ren, Congxin,Mao, Minyao,Wang, Weiyuan The Korean Vacuum Society 1998 Applied Science and Convergence Technology Vol.7 No.1

To apply diamond films in microelectromechanical systems(MEMS), it is necessary to develop the patterning technologies of diamond films in the micrometer scale. In this paper, three different kinds of technologies for patterning CVD diamond films carried out by us were demonstrated: selective growth by improved diamond nucleation in DC bias-enhanced microwave plasma chemical vapor deposition (MPCVD) system, selective growth of seeding using diamond-particle-mixed photoresist, and selective etching of oxygen ion beam using Al as the mask. It was show that high selectivity and precise patterns had been achieved, and all the processes were compatible with IC process.