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        Myeloid Sarcoma and Acute Myelomonocytic Leukemia in an Adolescent with Tetrasomy 8: Staging with $^{18}F$-FDG PET/CT

        Makis, William,Rakheja, Rajan,Lavoie, Josee,Hickeson, Marc The Korea Society of Nuclear Medicine 2012 핵의학 분자영상 Vol.46 No.2

        Tetrasomy 8 is a relatively rare chromosomal abnormality that has been reported in only 33 cases in hematologic disorders. It is known for its association with aggressive acute myeloid leukemia (AML) and myeloid sarcoma and is considered a very poor prognostic factor. Myeloid sarcoma is a rare hematologic malignancy characterized by tumor masses consisting of immature myeloid cells, presenting at an extramedullary site. We present a case of a 17-year-old boy referred for an $^{18}F$-FDG PET/CT for the evaluation of pleural masses and spinal bone lesions seen on CT, after presenting with a 4 month history of chest pain. The PET/CT revealed extensive FDG-avid extramedullary disease in the soft tissues of the chest, abdomen, and pelvis, which were biopsy-proven to be myeloid sarcoma, as well as extensive intramedullary disease biopsy proven to be AML. This is the first report of the use of $^{18}F$-FDG PET/CT to stage a subset of aggressive AML and myeloid sarcoma in a patient with an associated chromosomal abnormality (tetrasomy 8).

      • Synthesis and characterization of carbon microspheres from rubber wood by hydrothermal carbonization

        Ahmed Khan, Tanveer,Kim, Hyun‐,Joong,Gupta, Arun,Jamari, Saidatul S,Jose, Rajan John WileySons, Ltd 2019 Journal of chemical technology and biotechnology Vol.94 No.5

        <P><B>Abstract</B></P><P><B>BACKGROUND</B></P><P>Carbon is the raw material for many commercial products; conventionally their production is from non‐renewable sources such as petroleum coke, pitch and coal. Recently carbon has been obtained from bioresources because of their renewability and high lignocellulosic content. This article details the synthesis of carbon microspheres from rubber wood, which is one of the largest commodity plants, via hydrothermal carbonization (hydrothermal rubber wood carbon; HTRW carbon) and evaluation of their characteristics.</P><P><B>RESULTS</B></P><P>Two sets of carbon were synthesized: (i) in the first set, excess of water (20–40 × weight of biomass) was used in the hydrothermal process at 180–260 °C for 3–9 h; and (ii) in the second set, water ratio was 25–35 × weight of biomass and the hydrothermal carbonization (HTC) reaction temperature was fixed at 260 °C. The H/C and O/C ratios of starting rubber wood were ∼1.78 and ∼0.85, respectively, which upon processing through the first strategy resulted in H/C ∼0.78 and O/C ∼0.29; thereby suggesting increased condensation under HTC. On the other hand, the carbonization process was accelerated by water when the temperature was maintained at 260 °C; Fourier transform infrared (FTIR) studies show that this carbon has a different chemical structure from the starting rubber wood. Scanning electron microscopy (SEM) images showed that HTRW carbon was in the form of microspheres (size ∼1.5–5 µm).</P><P><B>CONCLUSION</B></P><P>HTRW carbon with carbon content as high as 68% was developed from rubber wood biomass by hydrothermal processing of a mixture containing 35 times more water than the solid raw biomass at a temperature of 260 °C for 7 h. © 2018 Society of Chemical Industry</P>

      • KCI등재

        Advances in stable and flexible perovskite solar cells

        Qamar Wali,Faiza Jan Iftikhar,Naveen Kumar Elumalai,Yaseen Iqbal,Sidra Yousaf,Shahid Iqbal,Rajan Jose 한국물리학회 2020 Current Applied Physics Vol.20 No.5

        Roll-to-roll (R2R) production is an innovative approach and is fast becoming a very popular industrial method for high throughput and mass production of solar cells. Replacement of costly indium tin oxide (ITO), which conventionally has served as the transparent electrode would be a great approach for roll to roll production of flexible cost effective solar cells. Indium tin oxide (ITO) and fluorine-doped tin oxide (FTO) are brittle and ultimately limit the device flexibility. Perovskite solar cells (PSCs) have been the centre of photovoltaic research community during the recent years owing to its exceptional performance and economical prices. The best reported PSCs fabricated by employing mesoporous TiO2 layers require elevated temperatures in the range of 400–500 °C which limits its applications to solely glass substrates. In such a scenario developing flexible PSCs technology can be considered a suitable and exciting arena from the application point of view, them being flexible, lightweight, portable, and easy to integrate over both small, large and curved surfaces.

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