http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Effects of Policosanol on Patients with Ischemic Stroke: A Pilot Open Study
R. Mas,L.L.Ortega,J. Schez,L. Ferndez,S. Mendoza,R. Gamez,J.C. Fernadez,J. Illnait,E. Alvarez 한국식품영양과학회 2006 Journal of medicinal food Vol.9 No.3
Stroke is a major health problem worldwide. Its pharmacological management includes thrombolytic therapyfor the acute phase and antiplatelet drugs for stroke recovery and prevention. Statins can help in the acute phase and in pre-venting stroke in secondary prevention patients. Policosanol is a cholesterol-lowering drug with concomitant antiplatelet ef-fects, with protective effects in stroke models. This observational study investigated the effects of policosanol (20 mg/day)with antiplatelets and vitamins. After hospital discharge, patients were followed up every 3 (first year) and 6 (thereafter)months. Neurological improvement was assessed with the modified Canadian Neurological Scale. Adverse events wererecorded. Fifty patients were included; all completed the study. Neurological score improved throughout the study. No pa-tient died, and most [40 (80.0%)] did not experience new vascular events; only one (2.0%) suffered a new stroke, and two(4.0%) suffered more than one transient ischemic attack. The time to the first recurrent event was 46.2 months. Policosanolpersistently lowered serum total cholesterol, with such reduction correlating with the neurological improvement (R.chemic stroke treated with aspirin and vitamins showed good results on neurological outcomes and recurrent events. Thisstudy, however, has limitations, since it was open and uncontrolled, and patients also consumed aspirin and vitamins. Newrandomized, controlled studies are needed to assess the usefulness of policosanol in stroke management.
Green Synthesis and Radial Breathing Modes in Ti Nanoparticles
R. Britto-Hurtado,M. CORTEZ-VALADEZ,Ramón A. B. Alvarez,P. Horta-Fraijo,J.-G. BOCARANDO-CHACON,R. Gamez-Corrales,A. Perez-Rodríguez,F. Martínez-Suarez,F. Rodríguez-Melgarejo,H. Arizpe-Chavez,M. FLORES 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2015 NANO Vol.10 No.5
This work presents the synthesis of metallic nanoparticles of titanium. The extract from the nopal (Opuntia ficus-indica) plant was used as the redactor agent. The results of transmission electronic microscopy (TEM) show that nanoparticles have a sphere-like shape with an approximate diameter of 1 – 4 nm. The presence of Ti in these particles was corroborated by energy dispersive X-ray spectroscopy (EDS). Optical properties were detected with the presence of absorption bands centered in 295 nm and 355 nm, similar to those reported in the literature. Two Raman bands centered at 359 cm-1 and 404 cm-1 were observed after the synthesis of titanium nanoparticles. Afterwards, structural and vibrational parameters of small clusters of Ti (Tin, n=3 – 13) were analyzed by the density functional theory (DFT) at the B3LYP level of approximation combined with the basis set LANL2DZ. Radial breathing modes (RBMs) were detected in the vibrational spectrum of each cluster, placed around 298 – 387 cm-1.
Perinatal/Postnatal Study of D-003, a Mixture of Long-Chain Fatty Acids, in Rats
M.D. Rodriguez,J.E. Gonzalez,E.F. Leon,A. Gutierrez,G. Marrero,R. Gamez,H Garcia,,E Goicochea,Y. Rodriguez,A. Gomez 한국식품영양과학회 2006 Journal of medicinal food Vol.9 No.2
D-003 is a mixture of long-chain fatty acids isolated and purified from sugar cane wax with cholesterol-low-ering and antiplatelet effects. In order to further characterize the developmental toxicity during the treatment period from lategestation up to weaning of the offspring, pregnant females received 0 (control), 500, and 1,000 mg/kg/day D-003 daily byoral gavage beginning at day 15 of pregnancy and through gestation until day 21 postpartum. Maternal clinical signs, bodyweight, and food intake were measured at regular intervals during gestation and lactation. Live pups were weighed, sexed,and examined for developmental signs. One female and male of each litter were randomly selected to evaluate the reproduc-tive potential. There were no spontaneous or dose-related maternal deaths during the course of this study. The general healthand behavioral condition of offspring was good in all groups. No significant differences among groups were found in com-parisons of litter size, survival through the weaning period, sex ratio, and male and female weights. This peri- and postnatalstudy conducted with D-003 in rats indicated that treatment of the dam during late gestation and lactation did not show ad-versely effects on reproductive performance or fetal development over two generations.