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( Pyung Chun Oh ),( Soon Yong Suh ),( Woong Chol Kang ),( Kyounghoon Lee ),( Seung Hwan Han ),( Taehoon Ahn ),( Eak Kyun Shin ) 대한내과학회 2016 The Korean Journal of Internal Medicine Vol.31 No.3
Background/Aims: Treatment of coronary in-stent restenosis (ISR) is still associated with a high incidence of recurrence. We aimed to compare the efficacy and safety of drug-eluting balloons (DEB) for the treatment of ISR as compared with conventional balloon angioplasty (BA) and drug-eluting stents (DES). Methods: Between January 2006 and May 2012 a total of 177 patients (188 lesions, 64.1 ± 11.7 years old) who underwent percutaneous coronary intervention for ISR were retrospectively enrolled. Clinical outcomes were compared between patients treated with DEB (n = 58, 32.8%), conventional BA (n = 65, 36.7%), or DES (n = 54, 30.5%). The primary end point was a major adverse cardiac event (MACE), defined as a composite of cardiac death, myocardial infarction, and target lesion revascularization (TLR). Results: Baseline characteristics were not different except for a history of previous MI, which was more frequent in patients treated by conventional BA or DES than in patients treated by DEB (40.0% vs. 48.1% vs. 17.2%, respectively, p = 0.002). The total incidences of MACEs were 10.7%, 7.4%, and 15.4% in patients treated by DEB, DES, or conventional BA, respectively (p > 0.05). TLR was more frequent in patients treated by conventional BA than in patients treated by DEB or DES, but this was not statistically significant (10.8% vs. 6.9% vs. 3.7%, p > 0.05 between all group pairs, respectively). Conclusions: This study showed that percutaneous coronary intervention using DEB might be a feasible alternative to conventional BA or DES implantation for treatment of coronary ISR. Further large-scaled, randomized study assessing long-term clinical and angiographic outcomes will be needed.
관상동맥 중재술을 시행받은 급성심근경색증 환자에서 고중성지방혈증과 복부 비만이 예후에 미치는 영향
오병천 ( Pyung Chun Oh ),한승환 ( Seung Hwan Han ) 대한내과학회 2014 대한내과학회지 Vol.86 No.2
Although there are still controversies about whether hypertriglyceridemia is an independent risk factor for coronary artery disease, recent analysis reported hypertriglyceridemia and central obesity are independent risk factors for coronary artery disease. However, the prognostic impact of hypertriglyceridemia and central obesity in acute myocardial infarction (AMI) patients underwent percutaneous coronary intervention (PCI) are still remained unclear. In this issue, Han et al. investigated the prognostic impact of hypertriglyceridemia and/or central obesity on baseline in AMI patients treated with PCI. In this editorial, we have reviewed the role of hypertriglyceridemia and central obesity on the prognosis after PCI in AMI patients. Although hypertriglyceridemia and central obesity on baseline in this study had no role on the prognosis following PCI in AMI patients, to confirm for these results, further studies on this topic will be warranted in the future. (Korean J Med 2014;86:165-168)
증례 : 신장 ; 혈액투석 환자에서 자연적으로 발생한 요관자연파열 1예
오병천 ( Pyung Chun Oh ),엄영실 ( Young Sil Eom ),박재찬 ( Jae Chan Park ),한우진 ( Woo Jin Han ),성주영 ( Ju Young Sung ),정우경 ( Woo Kyung Chung ),이현희 ( Hyun Hee Lee ) 대한내과학회 2009 대한내과학회지 Vol.76 No.2
요관자연파열은 요관의 기계적 조작, 외부 손상, 신수술의 과거력, 파괴성 신질환 없이 발생하는 경우를 말하며 매우 드물게 발생한다. 임상증상이 다양하고 급성복증(acute abdomen)과 감별하기 힘들기 때문에 진단이 어렵고 적절한 치료가 지연될 수 있다. 저자들은 진균성 농신장의 기왕력이 있는 혈액투석 환자에서 진균성 요로감염이 재발하고 요관자연파열이 발생하여 감염성 요종과 농양이 발생한 증례를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Spontaneous ureteral rupture is rare, and refers to leakage in the absence of prior ureteral manipulation, external trauma, previous surgery, or any destructive kidney disease. It presents a major diagnostic challenge due to the diversity at presentation. Here, we present a rare case of spontaneous ureteral rupture in a 62-year-old man with a history of fungal pyonephrosis (Candida) on maintenance hemodialysis, causing a large infected urinoma and abscess and a review the literature. (Korean J Med 76:229-233, 2009)
급성 관동맥증후군에서 예후평가를 위한 NT-proBNP, troponin 1, hs-CRP의 유용성
오병천 ( Pyung Chun Oh ),한승환 ( Seung Hwan Han ),정욱진 ( Wook Jin Chung ),강웅철 ( Woong Chol Kang ),서일혜 ( Yiel Hea Seo ),엄영실 ( Young Sil Eom ),문찬일 ( Chan Il Moon ),봉정민 ( Jeong Min Bong ),신미승 ( Mi Seung Shin ) 대한내과학회 2009 대한내과학회지 Vol.77 No.2
Background/Aims: Elevated levels of N-terminal pro-B-type natriuretic peptide (NT-proBNP), troponin I, and high-sensitivity C-reactive protein (hs-CRP) are each associated with higher rates of death and recurrent myocardial ischemia in patients with acute coronary syndrome (ACS). We evaluated the prognostic value of NT-proBNP and a multi-marker risk approach with the simultaneous assessment of NT-proBNP, troponin I, and hs-CRP in patients with ACS. Methods: We included 277 patients who were admitted for ACS between January and December 2006. We measured NT-proBNP, troponin I, and hs-CRP within 24 hours of the onset of symptoms. Patients were followed for a an of 559 days for cardiovascular events, including death, new myocardial infarction, heart failure, or rehospitalization for ACS. Results: NT-proBNP was the most powerful predictor of clinical outcome among the biomarkers (HR 3.65, 95% CI 2.11-6.30), followed by the peak troponin I and hs-CRP (HR 2.08, 95% CI 1.12-3.87; HR 1.99, 95% CI 1.18-3.37, respectively), but not the baseline troponin I. A multi-marker risk approach with the simultaneous assessment of NT-proBNP, hs-CRP, and peak troponin I was significantly associated with cardiovascular events, especially the presence of three positive biomarkers (adjusted HR 4.20, 95% CI 1.39-12.67). Conclusions: NT-proBNP is the most powerful, independent predictor of clinical outcome among the cardiac biomarkers. Since the peak troponin I level provides more prognostic information than the baseline level, follow-up measurement of troponin I may be warranted for risk stratification. The multi-marker risk approach appears to have better prognostic performance than any marker in isolation. (Korean J 77:200-210, 2009)
Reduction of labor in oyster mushroom cultivation by vinyl mulching on mushroom bed
Se-Jong Oh,Jeong-Sik Park,Pyung-Gyun Shin,Jong-Chun Cheong 한국버섯학회 2004 한국버섯학회지 Vol.2 No.1
Labor required for managing and harvesting the oyster mushroom bed was evaluated. Although vinyl mulching cultivation method needs more hours for spawning, it saves more than 50% of labor for harvesting and managing of the mushroom bed. Harvesting hour of 1st-3rd flush in vinyl mulching method was 48~50% for Plerutus ostreatus and 36~41% for P. sajor-caju. Labor for bed management after harvesting in vinyl mulching method was also 38~50% for P. ostreatus compared to conventional method, and 20~35% for P. sajor-caju. Vinyl mulching is believed to be a very efficient method for saving labor in oyster mushroom cultivation.
( Jongwook Yu ),( Pyung Chun Oh ),( Myeongjoo Son ),( Kyunghee Byun ),( Woong Chol Kang ) 대한내과학회 2016 대한내과학회 추계학술대회 Vol.2016 No.1
Background: Soluble ST2, an interleukin 33-related substance is a marker of biomechanical strain and has shown to be an independent predictor for adverse outcome in heart failure. We evaluated the prognostic value of soluble ST2 in ST-segment elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PCI). Methods: A total of 323 patients with STEMI undergoing primary PCI were enrolled and divided into two groups based on the median level of ST-2 measured at the time of presentation: the high ST2 group (ST2 ≥654 pg/mL, n=162) and the low ST2 group (ST2 <654 pg/mL, n=161). The primary endpoint was 1-year major adverse cardiovascular and cerebrovascular events (MACCE), defined as the composite of all-cause death, non-fatal MI, non-fatal stroke, and ischemia-driven revascularization. Results: Demographic, echocardiographic and angiographic characteristics were similar between the high and low ST2 groups. The cumulative incidence of MACCE at 1 year was significantly higher in the high ST2 group than in the low ST2 group (15.4% vs. 8.1%, p=0.044, Figure). By multivariate Cox regression analysis adjusting for age, sex, diabetes, anterior wall infarction, and systolic dysfunction (ejection fraction <40%), the high ST2 level was independently associated with 1-year MACCE (adjusted hazard ratio 2.09, 95% CI 1.01-4.29, p=0.046). Conclusions: The level of ST2 measured at the time of presentation can be a powerful, independent predictor of 1-year adverse clinical outcomes in patients with STEMI.
김현성,김일평,오상천,동진근 원광대학교 치의학연구소 1995 圓光齒醫學 Vol.5 No.2
There has been a lot of research into the essence of the smile, but so far just a few studies have been done on the relationship between personality and smile. On the assumption that smile aesthetics are closely related to individual physical condition and psychological state, this study investigated the correlation between personality factors and smile scores. The Personality Factor Questionnaire test was administered to 60 university students(male: 30, female: 30) who have no teeth missing, no experience of orthodontic or prosthodontic treatment and good dentition. Then, portraits were taken in a full smile. Esthetic smile scores were estimated by 10 appraisers who were dentists. These scores were analyzed statistically using the SAS program. The following results were obtained. 1. Personality factors of Warmth, Stableness, Surgency, Boldness, Untroubledadequacy, Group-dependence, Relaxation, Extraversion, Low anxiety were positively correlated to the aesthetic level of smile. 2. For females, personality factors had greater influence on smile aesthetics, whereas male smile aesthetics were less influenced by personality factors.