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        Acute Pancreatitis: A Rare Post-Colonoscopy Sequela

        Sujit P. Nair,Prasanta Debnath,Suhas Udgirkar,Parmeshwar Junare,Sanjay Chandnani,Shubham Jain,Vinay B. Pawar,Pravin M. Rathi 대한소화기내시경학회 2020 Clinical Endoscopy Vol.53 No.5

        Abdominal pain is a common but benign symptom after colonoscopy. We report a case of acute pancreatitis that occurred just after anelective screening colonoscopy; this is a rare event with very few reported cases. A healthy, asymptomatic male underwent screeningcolonoscopy at our center and developed abdominal pain and emesis after the procedure. An abdominal X-ray ruled out perforation but laboratory tests revealed elevated levels of amylase and lipase. The patient had no etiological risk factors for pancreatitis. Thepresumed mechanism of pancreatitis in this case is mechanical and pressure trauma from excessive insuffation, external abdominal pressure, and repeated withdrawal of the colonoscope due to tight angulation of the splenic flexure, a structure that is in close proximityto the pancreatic tail. Acute pancreatitis should be considered in the differential diagnosis of patients who present with abdominal painafter colonoscopy once more common etiologies have been excluded.

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        Normal Values of High-resolution Anorectal Manometry of Healthy Indians

        Rahul Deshmukh,Akash Shukla,Sanjay Chandnani,Pravin M Rathi,Pratik Tibdewal,Shubham Jain,Nitin Ramani,Parmeshwar Junare,Partha Debnath,Leela Shinde,Asif Bagwan,Megha Meshram 대한소화기 기능성질환·운동학회 2022 Journal of Neurogastroenterology and Motility (JNM Vol.28 No.3

        Background/AimsHigh-resolution anorectal manometry (HRAM) measures anal sphincter function and anorectal co-ordination. This study aims to provide normal data for HRAM and evaluate the effect of gender, age, and body mass index (BMI) on anorectal functions in healthy Indian subjects. MethodsHRAM was performed on 93 healthy volunteers using a 20-channel, water-perfused catheter. We evaluated anorectal pressures, rectal sensation, and balloon expulsion time. Measurements were recorded during rest, squeeze, and simulated defecation (push). ResultsMedian anal resting pressure (88 mmHg vs 94 mmHg, P = NS), anal squeeze pressure (165 mmHg vs 147 mmHg, P = NS) were not significantly different between males and females. Rectal pressure (70 mmHg vs 54 mmHg, P = 0.024) and anal pressure (82 mmHg vs 63 mmHg, P = 0.008) during simulated evacuation without rectal distention, were higher in males. The threshold for the first sensation was lower in females (40 mL vs 30 mL, P = 0.021) but desire to defecate (105 mL vs 90 mL, P = NS) and maximum tolerable volume (160 mL vs 140 mL, P = NS) were not significantly different in males and females. Anal residual pressure (median mmHg 83 vs 71 mmHg, P = 0.025) was higher in subjects < 40 years of age. Maximum anal squeeze pressure (185 mmHg vs 165 mmHg, P = 0.024) and maximum rectal pressure (75 mmHg vs 62 mmHg, P = 0.032) during push higher in BMI < 23 kg/m2. ConclusionsThe present study provides normal data for the Indian population that can be used for comparison and further work. Age, gender, and BMI affect anorectal parameters in HRAM and should be considered while reporting.

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