글쓰기 교육과 한문 교육의 앞으로의 방향

손병국,오정란,조규일,최기용,한지현 광운대학교 인문사회과학연구소 2000 인문사회과학논문집 Vol.29 No.-

Influence of Sensory Impairments on Incidence of Dementia in the Korean Population

Oh Gyu han,Jhoo Jin Hyeong,Park Sang-a,Jang Jae-Won,Kim Yeshin,Choe Young Min,Byeon Gihwan 대한신경정신의학회 2023 PSYCHIATRY INVESTIGATION Vol.20 No.6

Objective Previous studies have shown the influence of visual and auditory sensory impairment on dementia incidence. In this study, we tested the hypothesis that the incidence of dementia will increase with visual and auditory impairments than with visual or auditory impairment.Methods Data from the Korea National Health Insurance Service database were used, including disease and medication codes from 2009 to 2018, and the 2011 national health check-up results. Participants were grouped based on their sensory abilities: normal, visual impairment, auditory impairment, and both visual and auditory impairments (dual sensory impairment). To compare the incidence of dementia, hazard ratios were calculated for each group, with reference to the normal sensory (NS) group. Sensitivity analyses were performed comparing dementia incidence from 2014 to 2018, excluding the onset of the disease in 2012 and 2013.Results We identified 8,289 cases of dementia during the seven-year follow-up. In the multiple Cox regression analysis, adjusted for sex, social economic status, age, comorbidities, smoking, alcohol consumption, and activity level, the auditory impairment (hazard ratio= 1.1908) and visual impairment (hazard ratio=1.3553) groups showed a significantly higher dementia incidence than the NS group. Dual sensory impairment (hazard ratio=1.5267) showed the highest incidence. The sensitivity analysis yielded similar results.Conclusion Visual and auditory impairments are associated with an increased risk of dementia, particularly in individuals with dual sensory impairment. Hence, visual and auditory impairments might have increased the risk of dementia through independent pathological processes. Therefore, preventing and correcting sensory impairment is necessary to reduce the risk of dementia.

Efficacy and Safety of Fixed-dose Combination Therapy With Telmisartan and Rosuvastatin in Korean Patients With Hypertension and Dyslipidemia: TELSTA-YU (TELmisartan-rosuvaSTAtin from YUhan), a Multicenter, Randomized, 4-arm, Double-blind, Placebo-contro

Oh, Gyu Chul,Han, Jung-Kyu,Han, Ki Hoon,Hyon, Min-Su,Doh, Joon Hyung,Kim, Moo Hyun,Jeong, Jin-Ok,Bae, Jang-Ho,Kim, Sang Hyun,Yoo, Byung-Su,Baek, Sang Hong,Rhee, Moo-Yong,Ihm, Sang-Hyun,Sung, Jung Hoon Elsevier Science B.V., Amsterdam. 2018 Clinical therapeutics Vol.40 No.5

최근 10년간 국내 소 질병 원인체에 관한 문헌적 고찰

이한규 ( Han Gyu Lee ),조아라 ( Ara Cho ),오상익 ( Sang-ik Oh ),노재희 ( Jae-hee Roh ),정영훈 ( Yong Hoon Jung ),최창용 ( Changyong Choe ),도윤정 ( Yoon Jung Do ),엄재구 ( Jae Ku Oem ),손동수 ( Dong-soo Son ),류재규 ( Jae Gyu Yoo 한국동물위생학회(구 한국가축위생학회) 2020 韓國家畜衛生學會誌 Vol.43 No.3

For estimating the prevalence of bovine infectious disease agents, the pathogens were classified as follows: the digestive disease agents, respiratory disease agents, reproductive disease agents, and tick-borne disease agents. This study covered 81 published papers regarding bovine infectious diseases in Korea that determined the presence of diverse pathogens or the antibodies elicited by the infectious agents in cattle from 2010 to 2019. In total, 59,504 cows were involved in the papers reporting the causative agents in their cases. The disease prevalence for the digestive, respiratory, reproductive, and tick-borne cases was 9.0%, 13.4%, 10.4%, and 7.8%, respectively. Bovine viral diarrhea virus, Escherichia coli, Mycobacterium avium subsp. paratuberculosis, and Eimeria spp were more significantly prevalent in the cows under one-year age than over one-year age. Bovine viral diarrhea virus, Escherichia coli, Mycobacterium avium subsp. paratuberculosis, and Anaplasma spp. were more significantly prevalent in Hanwoo than dairy cattle. Coxiella burnetii, Neospora caninum, and Theilieria spp. were more significantly prevalent in dairy cattle than Hanwoo. Tick-borne disease agents were more prevalent in cows grazing than the case in housing. Our analytic data obtained from this study emphasize the need for more studies on the occurrence of these pathogens according to the breed, age, and the region, to come up with bovine infectious disease control measures in Korea.

과학기술위성 3호 S-대역 송신기 인증모델 설계 및 제작

오승한(Seung-Han Oh),서규재(Gyu-jae Seo),오대수(Dae-Soo Oh),이정수(Jung-Soo Lee),오치욱(Chi-Wook Oh) 한국항공우주학회 2010 韓國航空宇宙學會誌 Vol.38 No.1

본 논문은 현재 KAIST 인공위성연구센터(SaTReC)에서 개발하고 있는 과학기술위성3호(STSAT-3) 위성본체의 S대역 통신채널 중 송신기 개발에 관하여 서술하고 있다. STSAT-3의 통신시스템은 위성제어 및 상태정보 전송을 위하여 S대역을 사용하며 임무수행용 통신채널로는 X대역을 사용하고 있다. S대역 송신기(S band Transmitter, STX)는 변조기, 주파수 합성기, 파워 앰프, 전력공급기 로 구성되어 있다. 변조 방법으로는 주파수 천이방식(Frequency Shift Keying, FSK)을 사용 하며 위성체와는 RS-422통신 방식을 이용한다. STSAT-3의 STX는 모듈화에 근거하여 설계 및 제작 되었으며 1.5W(31.7dBm) 송신 출력에 1E-5 비트오율(BER) 성능을 만족한다. 현재 성능시험, 환경시험(진동시험, 열진공시험)을 성공적으로 마쳤다. This paper describes the development result of S-band Transmitter of STSAT-3 by satellite research center(SaTReC), KAIST. STSAT-3 has two kinds of communication channels, S- band for Telemetry & Command and X-band for mission payload. S-band Transmiiter(STX) consist of modulator, frequency synthesizer, power amp and DC/DC converter. The modulation scheme of STX is FSK(Frequency Shift Keying). The interface between spacecraft OBC and STX is RS-422. The STX is based on modular design. The RF output power of STX is 1.5W(31.7dBm) and BER of STX is under 1E-5. The Test of STX is completed successfully such as functional Test and environmental(vibration, thermal vacuum) Test.

The incidence and configuration of the bifid mandibular canal in Koreans by using cone-beam computed tomography

Kang, Ju-Han,Lee, Kook-Sun,Oh, Min-Gyu,Choi, Hwa-Young,Lee, Sae-Rom,Oh, Song-Hee,Choi, Yoon-Joo,Kim, Gyu-Tae,Choi, Yong-Suk,Hwang, Eui-Hwan Korean Academy of Oral and Maxillofacial Radiology 2014 Imaging Science in Dentistry Vol.44 No.1

Purpose: This study was performed to investigate the incidence and configuration of the bifid mandibular canal in a Korean population by using cone-beam computed tomography (CBCT) imaging. Materials and Methods: CBCT images of 1933 patients (884 male and 1049 female) were evaluated using PSR-9000N and Alphard-Vega 3030 Dental CT units (Asahi Roentgen Ind. Co., Ltd, Kyoto, Japan). Image analysis was performed by using OnDemand3D software (CyberMed Inc., Seoul, Korea). The bifid mandibular canal was identified and classified into four types, namely, the forward canal, buccolingual canal, dental canal, and retromolar canal. Statistical analysis was performed by using the chi-squared test and one-way analysis of variance (ANOVA). Results: Bifid mandibular canals were observed in 198 (10.2%) of 1933 patients. The most frequently observed type of bifid mandibular canal was the retromolar canal (n=104, rate: 52.5%) without any significant difference among the incidence of each age and gender. The mean diameter of the accessory canal was 1.27 mm (range: 0.27-3.29 mm) without any significant difference among the mean diameter of each type of the bifid mandibular canal. The mean length of the bifid mandibular canals was 14.97mm(range: 2.17-38.8 mm) with only a significant difference between the dental canal and the other types. Conclusion: The bifid mandibular canal is not uncommon in Koreans and has a prevalence of 10.2% as indicated in the present study. It is suggested that a CBCT examination be recommended for detecting a bifid canal.

Poster Session : PS 1376 ; Nephrology : Delta Neutrophil Index as an Independent Predictor of Mortality in Septic Acute Kidney Injury Patients Under-going Continuous Renal Replacement Therapy

( In Mee Han ),( Dong Ho Shin ),( Youn Kyung Kee ),( Chang Yun Yoon ),( Eunyoung Lee ),( Young Su Joo ),( Seung Gyu Han ),( Hyung Jung Oh ),( Jung Tak Park ),( Seung Hyeok Han ),( Shin Wook Kang ),( T 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

Background: Delta Neutrophil Index (DNI) indicates the fraction of circulating immature granulocytes, which is known to increase in infectious and/or septic conditions. However, the relationship between DNI and mortality in septic acute kidney injury (AKI) patients is not yet fully elucidated. Therefore, we assessed whether DNI is associated with mortality in septic AKI patients requiring continuous renal replacement therapy (CRRT). Methods: We retrospectively enrolled 285 patients with septic AKI who were treated with CRRT at Yonsei University Health System between August 2009 and September 2012. The patients were dichotomized into high and low DNI groups based on the cutoff value from receiver operating characteristics of DNI values at the time of CRRT initiation. Log-rank test and Cox proportional hazards analysis were conducted to evaluate the effect of DNI as a prognostic factor for 28-day all-cause mortality. Results: The mean age of the enrolled patients was 61.0 ± 14.7 years and 180 patients (63.2%) were male. The high DNI group (DNI > 5.6%) was composed of 149 patients (52.3%). During the study period, 192 patients (67.1%) died. Mortality rate during the 28-days was significantly increased in the high DNI group compared to low DNI group (79.9% vs. 53.3%, P < 0.01, log rank test p Conclusions: This study demonstrates that DNI at CRRT initiation could be an useful predictor for mortality in septic AKI patients requiring CRRT.

VLBI 시스템의 시각동기 유지를 위한 제어 및 모니터링 프로그램 개발

송민규 ( Min Gyu Song ),변도영 ( Do Young Byun ),위석오 ( Seog Oh Wi ),강용우 ( Yong Woo Kang ),제도흥 ( Do Heung Je ),오세진 ( Se Jin Oh ),한석태 ( Seog Tae Han ),김봉규 ( Bong Gyu Kim ) 대한설비관리학회 2010 대한설비관리학회지 Vol.15 No.4

In this paper, we discuss an approach for interface design and implementation of M&C(Monitoring & Control) program for the synchronizing of VLBI systems. In the case of VLBI based astronomical observation, there is arrival time difference of radio signal between each radio telescope. By using this timing difference properly, it is possible to accurately measure relative location of celestial bodies as well as each observatory, and to achive this goal in VLBI observation, it is necessary to record radio signals with precise time data. For the implementation of the system, in this paper, we examine standard clock and GPS time comparator with relevance to hydrogen maser providing reference frequency, and discuss the design and implementation of M&C program. And finally, we demonstrate efficient management of time data and clock system operation in VLBI observatory.

과학기술위성 3호 S-대역 송신기 비행모델 설계, 제작 및 시험

오승한(Seung-Han Oh),서규재(Gyu-Jae Seo),이정수(Jung-Soo Lee),오치욱(Chi-Wook Oh),박홍영(Hong-Young Park) 한국항공우주학회 2011 韓國航空宇宙學會誌 Vol.39 No.6

본 논문에서는 현재 KAIST 인공위성연구센터(SaTReC)에서 개발 진행 증인 과학기술위성3호(STSAT-3) 위성체의 위성 상태정보 전송을 위한 S-대역 송신기 비행모델 개발 및 시험에 관하여 서술하고 있다. STSAT-3의 통신시스템은 크게 상태정보, 명령 송수신을 위한 통신채널과 임무데이터 전송을 위한 통신채널로 구성되며 상태 정보 및 명령 송수신을 위하여 S-대역을 사용하며 임무데이터 전송용으로 χ-대역 주파수를 사용하고 있다. S-대역 송신기(S-band Transmitte, STX)는 기능적으로 변조기, 주파수 합성기, 파워 앰프 및 전력공급기 로 구성되어 제작되었다. 전송데이터 변조 방법으로는 주파수 천이방식 (Frequency Shift Keying, FSK)을 사용 하며 위생본체와의 데이터 통신은 표준방식인 RS-422통신 방식을 사용하였다. STSAT-3의 STX는 기능적 모듈화에 근거하여 설계 및 제작 되었으며 1.5W(31.7㏈m) 송신 출력에 1X10?? 비트오율(BER) 성능을 만족한다. STX 비행모델은 성능시험, 환경시험(진동시험, 열진공시험)을 성공적으로 마치고 위성체 조립단계에 납품되었다. This paper describes the development and test result of S-band Transmitter flight model(FM) of STSAT-3 by satellite research center(SaTReC), KAIST. The communication sub-system of STSAT-3 is consist of two different frequency band channels, S-band for Telemetry & Command and X-band for mission data. S-band Transmitter(STX) functionally made of modulator, frequency synthesizer, power amp and DC/DC converter. The transmission data is modulated by FSK(Frequency Shift Keying) and the interface between spacecraft sub-module and STX is RS-422 standard method. The FM STX is based on modular design. The RF output power of STX is 1.5W(31.7㏈m) and BER of STX is under 1X10?? which meets the specification respectively. The FM STX is delivered Spacecraft Assembly, Integration and Test(AIT) level through the completion of functional Test and environmental(vibration, thermal vacuum) Test successfully.

척수 편측절단 손상 후 일회성 운동량에 따른 neurotrophins 단백질발현 및 수용체 활성

오명진 ( Myung Jin Oh ),한재덕 ( Jae Duk Han ),서태범 ( Tae Beom Seo ),김종오 ( Jong Oh Kim ),정일규 ( Il Gyu Jeong ) 한국운동생리학회(구 한국운동과학회) 2011 운동과학 Vol.20 No.4

오명진, 한재덕, 서태범, 김종오, 정일규. 척수 편측절단 손상 후 일회성 운동량에 따른 neurotrophins 단백질발현 및 수용체 활성. 운동과학, 제20권 제4호. 475-486, 2011. 본 연구는 흰쥐의 흉추 9번을 반측절단 손상을 유발시키고, 1주 동안의 휴식 후 저강도 운동 처치를 15분, 30분, 60분, 90분으로 나누어 1회 실시하였으며, 운동직후 손상신경조직을 적출하여 형태적 변화와 신경성장관련 인자들의 발현정도를 분석하였다. 실험동물은 7주령된 SD계열 수컷 흰쥐 60마리를 실험대상으로 normal 그룹, 척수손상(SCI) 대조군, SCI+운동15분그룹, SCI+운동30분그룹, SCI+운동60분그룹, SCI+운동90분그룹으로 총 6그룹으로 설정하였다. 운동처치는 저강도운동으로 1회 실시하였다. 그 결과 BDNF 단백질의 발현량은 운동 60분 > 30분 > 90분 > 15분순으로 60분에서 가장 많이 발현되었으며, 수용체인 TrkB mRNA의 발현량은 30분 운동그룹에서만 높게 발현되었다. NGF 단백질 발현량은 손상 후 운동그룹 모두가 손상그룹보다 높게 나타났으며, 수용체인 TrkA mRNA의 발현량은 운동 15분 > 60분 > 30분, 90분순으로 운동 15분에 가장 높게 발현되었다. NT3 단백질 발현량에서는 운동 30분, 60분 > 90분 > 15분순으로 운동 30분과 60분에서 높게 나타났으며, 수용체인 TrkC mRNA의 발현량은 운동 30분 > 60분, 90분 > 15분순으로 운동 30분에서 가장 높게 발현되었다. 형태학적인 변화로 반응성 별아교세포의 변화는 일회적인 운동량만으로는 변화가 나타나지 않는 것을 확인하였다. 이상의 결과를 종합한 결론은 척수손상 후 운동처치에 따른 신경성장관련 인자들의 발현량은 운동약 30분~60분정도에서 높게 나타나는 것을 확인하였다. Oh, M. J., Han, J. D., Seo, T. B., Kim, J. O., Jeong, I. G. The effects of quantity of treadmill exercise on expression of neurotrophins and receptor after spinal cord hemisection in the rats. Exercise Science. 20(4): 475-486, 2011. Sixty male Sprague-Dawley rats (230±10 g; 7 week in age) were assigned equally to six different groups; Normal (n=10), Spinal cord injury (SCI)(n=10), SCI+15m treadmill training (TMT)(n=10), SCI+30 mTMT (n=10), SCI+60 mTMT (n=10), SCI+90 mTMT (n=10). Every rat in SCI and SCI+TMT groups underwent laminectomy at thoracic vertebra ninth(T9) level and then hemisection the exposed spinal cord site in the anesthetized condition. After one week-recovery from injury, rats in SCI+TMT group exercised on a motorized treadmill for 15, 30, 60, 90 min/d. All tissues were used for H&E, immunofluorescence staining, Western blot and RT-PCR. The data obtained were analyzed by one-way ANOVA and Tukey`s post-hoc. and presented as mean±standard deviation. BDNF induction levels in the injured spinal cord significantly showed more increases in exercise group with SCI and were highly correlated with time of exercise, but NGF did not differ from another groups. TrkB mRNA which is receptor for BDNF was increased in only exercise group for 30 minutes and TrkA mRNA which is receptor for NGF was upregulated in two exercise group for 15 and 60 minutes. Also, TrkC mRNA, activated by NT-3, was significantly enhanced in exercise group for 30 minutes. Thus present data suggest that exercise plays a important role for axonal regeneration and functional recovery after SCI.