알레르기 환자에서 혈청 IgE와 특이항원 양성율의 일치도

남해선,권준택,박준수 순천향의학연구소 2000 Journal of Soonchunhyang Medical Science Vol.6 No.2

To evaluate usefulness of serum IgE to determine specific allergens, authors conducted priest IgE and MAST-CLA allergen-specific IgE assays in 78 allergic patients diagnosed at Soonchunhyang University Chunan Hospital during October 1998 through July 2000. During the study period, inhalent and food Korean panels were applied in 57 (73.1%) and 21 outpatients (26.9%), respectively. Kappa index was calculated to evaluate the agreement of priest IgE with Total IgE and allergen-specific IgE by MAST-CLA. 1. The men (±SD) age was 13.2 (±14.1) year-old and male accounted for 62.8%. 2. The overall positive rate of priest IgE was 66.7% and mean (±SD) level of priest IgE was 271.2 (±265.6) IU/ml 3. Patients with more than one specific allergen and with elevated total IgE by MAST-CLA were 25 (32.1%) and 33 (42.3%), respectively. 4. Significant agreement between total IgE and allergen-specific IgE was shown, but strength of agreement was slight (Kappa = 0.186, P = 0.046), 5. While no significant agreement between priest IgE and total IgE was observer, the priest IgE agreed significantly with allergen-specific IgE (Kappa = 0.153, P=0.043) In conclusion, our data suggested that serum priest IgE is more likely associated with allergen-specific IgE than total IgE in MAST-CLA assay. Furthermore, it is recommended that Korean panel of MAST-CLA should contain more specific allergens.

알레르기 환자에서 MAST-CLA 검사의 의의

남해선,황규윤,,백병준,정윤영,오천환,조성란,박준수 순천향의학연구소;Soonchunhyang Medical Research Institute 2000 Journal of Soonchunhyang Medical Science Vol.6 No.1

To evaluate usefulness of application of MAST-CLA to indetify allergens, authors conducted MAST-CLA allergen-specific IgE assay and collected allergy related symptoms in 118 allergic patients diagnosed at Soonchunhyang University Chunan Hospital during October 1998 through January 2000. The results were as followings; 1. The mean (SD) age was 23.1 (±12.17) years old and teenagers accounted for 33.1% of patients. 2. The frequent allergic symptoms were sneezing (59.3%), rhinorrhea (53.4%), nasal stiffness (44.1%), itching sensation (24.6%), cough or sputum (16.1%), and eye symptom (8.5%) in order. 3. Among these subjects, 62.7% of patients revealed at least more than one specific allergen and 70.3% showed elevated total IgE levels by MAST-CLA. The three most frequent specific allergens were Dermatophagoides farinae (47.5%), Dermatophagoides pteronyssinus (45.8%), and house dust (30.5%). 4. While age was not significantly related to positive of both specific allergens and total IgE (P>0.05), sneezing and nasal stiffness were significantly associated with positive of specific allergen and total IgE, respectively (both P<0.05). 5. Total IgE increased with the number of specific allergens, but both specific allergen and total IgE were not significantly related to increases of allergic symptoms (P>0.05). In conclusion, our data suggest that MAST-CLA allergen-specific IgE assay is useful measure for identification of causative allergens in allergic patients, however, it is recommended that more specific allergic antigens should be determined and replaced or added to Korean inhalent panel of MAST-CLA.

알레르기성 소인이 없는 정상인에서 특이 알레르겐항체 양성율

남해선,안현철,박준수,황규윤,박춘식 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.2

This study was designed to evaluate prevalence of allergen-specific antibodies in healthy adults. During Mar. ~ Aug. 2001, 1,925 subjects visited for medical check-up, were inquired to fill out a standardized questionnaire. Among them, 200 subjects who had no current and past allergic disorders were randomly selected for rhe current study and examined for allergen-specific antibodies using Korean inhalant panel of MAST-CLA allergen-specific IgE assay. Among them, 170 persons (85.0%) did not have any positive allergen-specific antibody. Each positive rate of 35 allergen specific antibodies was usually less than 3%, except Cockroach Mix (3.5%), Dermatophagoides farinae(8.5%), Dermatophagoides pteronyssinus(6.0%). Among 30 positive subjects, 19(63.3%) showed one or two allergen-specific antibodies. Although atopic subjects in non-allergic population were not common, few of them showed allergen-specific antibodies in Korean inhalant panel of MAST-CLA. Our results suggested that the standardized questionnaire and MAST-CLA could be an useful tool of a screening test for allergy, showing high specificity and sensitivity.

중격측좌핵 및 선조체기저핵의 아미노산 함량에 대한 한쪽 뇌 해마 제거의 영향

남준철,김종규 순천향의학연구소 1996 Journal of Soonchunhyang Medical Science Vol.2 No.2

We analyzed the amino acid contents of fundus striatal and accumbens septal tissue in unilateral hippocampectomized rats by high performance liquid chromatography(HPLC). Thirty-one male rats were divided into hippocampal, cortical control and normal control groups. After a survival period of 7 days, the animals were sacrificed by decapitation. Two to three milligrams of tissue were removed from the nucleus fundus striati and the nucleus accumbens septi in ipsilateral or contralateral side of the brain. In the nucleus accumbens septi, the contents of glutamate were reduced significantly in the ipsilateral hippocampal group and increased significantly in the contralateral hippocampal group than in the normal control group and the cortical control group, while there were no significant differences between the 2 control groups. The contents of glycine were reduced significantly in the contralateral hippocampal group than in the normal control group and the cortical control group. But in the nucleus fundus striati, the difference of contents of all amino acids were nonsignificant. From the above results it is suggested that the ipsilateral hippocampus may exert a direct effect on the accumbens septi than the contralateral hippocampus.

지역사회 정신보건사업을 위한 환자 발견 체계에 관한 연구 : Case Detection and Delivery Method

남정현,박준혁,박용천,신영전 漢陽大學校 精神健康硏究 1998 精神健康硏究 Vol.17 No.-

Goeth의 時에 나타난 東方의 受容에 關한 硏究 I. : Goethe 와 中國

張南駿 中央大學校 人文科學硏究所 1984 人文學硏究 Vol.11 No.-

웹 기반 공동작업 지원시스템의 개발

문남두,안건태,김진홍,박양수,이명준 울산대학교 2001 공학연구논문집 Vol.32 No.1

최근 웹의 확산과 더불어 제품개발을 위하여 공동작업 구성원들 사이의 정보 공유와 재사용을 지원하는 웹 기반의 공동작업 지원 시스템 개발에 대한 관심이 고조되고 있다. 기업 및 공공기관의 공동작업은 광범위하게 분산되어 있는 경우가 많으며, 여러 작업그룹 내의 구성원은 이러한 환경에서 효과적으로 서로의 정보를 교환하고 공유할 수 있는 작업공간을 필요로 한다 또한 공동작업의 결과로서 생성된 기술문서의 체계적인 관리 기능과 실시간 의사전달의 기능 등이 함께 제공되는 것이 바람직하다. 본 논문에서는 웹 기반의 공동작업 지원 시스템인 CoWare의 설계와 구현에 대하여 설명한다. CoWare는 통합시스템으로서 CoSpace, CoDocs, CoMail로 명명된 세 개의 관련된 시스템으로 구성된다. CoSpace는 자료의 저장과 공유를 위하여 개인 및 작업그룹을 위한 작업공간을 제공하고, CoDocs는 전자문서의 체계적인 관리를 지원하며, CoMail은 실시간 의사전달의 기능을 제공한다. CoSpace, CoDocs, 그리고 CoMail은 기본적으로 사용자 정보, 사용자 그룹정보, 작업그룹정보의 공유를 통하여 상호 연계되어, 보다 자연스럽고 효율적으로 공동작업을 지원할 수 있다. With rapid growth of World-Wide Web(WWW or Web), much interest has shifted to develop a Web-based collaborative work system which supports information sharing and reusing. Most of collaborative works in a company or a public corporation are widely distributed. In such an environment, members of work groups require workspaces for exchanging and sharing information. In addition to those workspaces, it is desirable to support real-time messaging facility and systematic management of technical documents produced during collaborative works. In this paper, we describe the design and implementation of a Web-based groupware, named CoWare, which supports effective collaboration. The CoWare system is an integrated system including three related systems : CoSpace, CoDocs and CoMail. The CoSpace system provides personal workspace and shared workspace for storing and sharing informations. The CoDocs system manages electronic documents systematically, while the CoMail system supports real-time messaging facility. Basically, the user information, the user group information, and the work group information are shared among CoSpace, CoDocs, and CoMail. Thereby, the CoWare system supports more natural and effective collaboration.

港灣 시스템의 生産性 堤高를 위한 戰略的 計劃에 관한 硏究

許南秀,梁漢洙,金俊式,崔德哲 慶南大學校 産業經營硏究所 1990 産業經營 Vol.13 No.-

전문지식을 기반으로 한 지능형 운동처방 시스템

강남호,박충희,이상준 제주대학교 공과대학 첨단기술연구소 2002 尖端技術硏究所論文集 Vol.13 No.2

This paper is about a study on computer system, which prescribes and recommends someone's suitable exercise based on the data of physical and mental features that people have. This paper shows the method of specialization and process of user's feature informations. This method is realized and evaluated about its efficiency based on the knowledge of exercise prescriptive expert.

독일 낭만주의의 국가 이념

장남준 中央大學校 人文科學硏究所 1998 人文學硏究 Vol.27 No.-