채종박 품질이 이유돈의 성장에 미치는 영향

강창원,남기택,임호중,공진훈,안상태 한국축산학회 1995 한국축산학회지 Vol.37 No.4

This study was made to evaluate the nutritional values and glucosinolate contents of three types of rapeseed oil meal(RSM), originated from Canada(canola), China(CRSM:Chinese Rapeseed Oil Meal) and India (IRSM:Indian Rapeseed Oil Meal), and their dietary effects on the performance of weanling pigs. Nutritional evaluation included the contents of moisture, crude protein(CP), ether extracts (EE), crude fiber(CF), Ash, Ca and P, KOH solubility, tannin, and glucosinolate contents of each RSM. Total of two hundred-forty weanling pigs weighing about 20㎏ initially were housed in 24 pens with 10 pigs per pen. The thirty animals were assigned to one of eight rations : T₁ (0% RSM + 2% molasses), T₂ (6% canola + 2% molasses), T₃ (6% CRSM + 2% Molasses), T₄(6% IRSM + 2% molasses), T_5 (0% RSM + 5% molasses), T_6 (6% Canola + 5% molasses). T_7 (6% CRSM + 5% molasses), T_8 (6% IRSM + 5% molasses). During the experimental period, body weight and feed intakes were measured weekly and feed conversion rates were calculated. The results obtained from this experiments are summarized as follows. 1. The KOH solubility of canola, CRSM and IRSM was found to be 54.6, 35.7 and 64.8%, respectively. The glucosinolate contents of canola, CRSM and IRSM were found to be 0.11, 0.22 and 0.79%, respectively. 2. There were no significant differences between the 2% molasses and the 5% molasses supplemented groups in feed intake and body weight gain. 3. The 6% CRSM(T₃, T_7) and IRSM(T₄, T_8) groups were significantly (P$lt;0.05) inferior to the control groups(T₁, T_5) and 6% canola groups(T₂, T_6) in feed intake and body weight gains. The control groups(T₂, T_6) were significantly (P$lt;0.05) superior to the 6% canola groups(T₂, T_6), 6% CRSM(T₃, T_7) and 6% IRSM groups(T₄, T_8) in feed conversion rate.

Prediction of pathologic staging with magnetic resonance imaging after preoperative chemoradiotherapy in rectal cancer: Pooled analysis of KROG 10-01 and 11-02

Lee, J.H.,Jang, H.S.,Kim, J.G.,Lee, M.A.,Kim, D.Y.,Kim, T.H.,Oh, J.H.,Park, S.C.,Kim, S.Y.,Baek, J.Y.,Park, H.C.,Kim, H.C.,Nam, T.K.,Chie, E.K.,Jung, J.H.,Oh, S.T. Elsevier Science Publishers 2014 Radiotherapy and oncology Vol.113 No.1

Background and purpose: The reported overall accuracy of MRI in predicting the pathologic stage of nonirradiated rectal cancer is high. However, the role of MRI in restaging rectal tumors after neoadjuvant CRT is contentious. Thus, we evaluate the accuracy of restaging magnetic resonance imaging (MRI) for rectal cancer patients who receive preoperative chemoradiotherapy (CRT). Methods and materials: We analyzed 150 patients with locally advanced rectal cancer (T3-4N0-2) who had received preoperative CRT. Pre-CRT MRI was performed for local tumor and nodal staging. All patients underwent restaging MRI followed by total mesorectal excision after the end of radiotherapy. The primary endpoint of the present study was to estimate the accuracy of post-CRT MRI as compared with pathologic staging. Results: Pathologic T classification matched the post-CRT MRI findings in 97 (64.7%) of 150 patients. 36 (24.0%) of 150 patients were overstaged in T classification, and the concordance degree was moderate (k=0.33, p<0.01). Pathologic N classification matched the post-CRI MRI findings in 85 (56.6%) of 150 patients. 54 (36.0%) of 150 patients were overstaged in N classification. 26 patients achieved downstaging (ycT0-2N0) on restaging MRI after CRT. 23 (88.5%) of 26 patients who had been downstaged on MRI after CRT were confirmed on the pathological staging, and the concordance degree was good (k=0.72, p<0.01). Conclusions: Restaging MRI has low accuracy for the prediction of the pathologic T and N classifications in rectal cancer patients who received preoperative CRT. The diagnostic accuracy of restaging MRI is relatively high in rectal cancer patients who achieved clinical downstaging after CRT.

Comparison of the Haas and the Oxford classifications for prediction of renal outcome in patients with IgA nephropathy

Park, K.S.,Han, S.H.,Kie, J.H.,Nam, K.H.,Lee, M.J.,Lim, B.J.,Kwon, Y.E.,Kim, Y.L.,An, S.Y.,Kim, C.H.,Doh, F.M.,Koo, H.M.,Oh, H.J.,Kang, S.W.,Choi, K.H.,Jeong, H.J.,Yoo, T.H. W. B. Saunders Co ; Centrum Philadelphia 2014 Human pathology Vol.45 No.2

Pathologic features can provide valuable information for determining prognosis in IgA nephropathy (IgAN). However, it is uncertain whether the Oxford classification, a new classification of IgAN, can predict renal outcome better than previous ones. We conducted a retrospective cohort study in 500 patients with biopsy-proven IgAN between January 2002 and December 2010 to compare the ability of the Haas and the Oxford classifications to predict renal outcome. Primary outcome was a doubling of the baseline serum creatinine concentration (D-SCr). During a mean follow-up of 68months, 52 (10.4%) and 35 (7.0%) developed D-SCr and end-stage renal disease, respectively. There were graded increases in the development of D-SCr in the higher Haas classes. In addition, the primary endpoint of D-SCr occurred more in patients with the Oxford M and T lesions than those without such lesions. In multivariate Cox regression analyses, the Haas class V (HR, 12.19; P=.002) and the Oxford T1 (hazard ratio [HR], 6.68; P<.001) and T2 (HR, 12.16; P<.001) lesions were independently associated with an increased risk of reaching D-SCr. Harrell's C index of each multivariate model with the Haas and the Oxford classification was 0.867 (P=.015) and 0.881 (P=.004), respectively. This was significantly higher than that of model with clinical factors only (C=0.819). However, there was no difference in C-statistics between the 2 models with the Haas and the Oxford classifications (P=.348). This study suggests that the Haas and the Oxford classifications are comparable in predicting progression of IgAN.

사료내 식물성 Phytase 첨가가 산란계의 생산성 및 인 이용성에 미치는 영향

권순관,김성권,안병기,양운목,강창원,강석진,남기택 한국동물자원과학회 2002 한국축산학회지 Vol.44 No.1

본 연구는 식물성 phytase 처리수준이 산란계의 생산성에 미치는 영향 및 인 이용률에 미치는 영향을 검토하기 위하여 실시하였다. NRC 사양표준의 유효 인 요구량을 충족시킨 대조구와 무기태인 사용량을 50%로 제한한 처리구로 나누고, 각각의 처리구에 식물성 phytase를 각각 0.05%, 0.1% 및 0.2% 첨가하였다. 58주령의 갈색 산란계(ISA-Brown) 240수를 공시하여 총 6주간 사양실험을 실시하였고 산란종계를 이용하여 인 및 질소의 이용성을 측정하였다. 그 결과를 요약하면 다음과 같다. 1. 50% 무기태인 수준에서 식물성 phytase의 첨가에 따른 일당증체량, 산란율의 저하는 나타나지 않았다. 2. 50% 무기태인 수준에서 식물성 phytase 0.05% 첨가수준에서 일시적으로 난각질 저하 현상이 나타났으나 0.1% 이상 첨가수준에서는 난각질의 변화가 관찰되지 않았다. 3. 효소의 첨가수준이 증가함에 따라 P 배설량의 감소와 P 이용률이 개선되었다(P<0.05). 4. 식물성 phytase 첨가는 산란계의 성적 저하없이 사료내 무기태인의 사용량을 줄일 수 있음이 시사되었다. Two experiments were conducted to investigate the effect of dietary supplementation of plant phytase(Phytazyme^R) in corn-soybean meal based diets on utilization of phytase-bound phosphorus in laying hens and evaluate nitrogen(N) digestibility and phosphorus(P) availability in breeders. In he experiment one, three levels of the Phytazyme^R(0.05, 0.1, and 0.2% of diet) were added to diets containing a half of control TCP level(0.96%) for 4 wks. Feed consumption, egg production rate, egg weight and eggshell quality were recorded weekly. At the end of experiment, 8 birds per treatment were sacrificed, liver weight were weighed and right tibiae were removed for determination of P content. The second experiment was conducted to evaluate the P availability and nitrogen digestibility in breeders fed same diets for 2 wks. Feed and excreta were collected to determine the P and N contents for the last three days of experiment two. Addition of Phytazyme^R resulted in no effects on feed intake, egg product rate, egg weight and egg shell quality. P excretion decreased and its availability enhanced as phytase supplementation increased in diets. Dietary supplementation of Phytayme ^R above 0.1% level in corn-soybean meal based diets did not have an adverse effect on production and decreased level of phosphorus in excreta.

인버터 고전압 전원공급장치를 이용한 펄스전원공급장치 연구

박성수(S.S. Park),김상희(S.H. Kim),황정연(J.Y. Hwang),남상훈(S.H. Nam),이경태(K.T. Lee),김흥근(H.G. Kim) 전력전자학회 2004 전력전자학술대회 논문집 Vol.- No.-

The klystron-modulator(K&M) system of the Pohang Light Source(PLS) had been supplying high power microwaves for the acceleration of 2.5 GeV electron beams since October 2002. There are 12 sets of K&M systems to accelerate electron beams to 2.5GeV nominal beam energy. One module of the K&M system consists of an 80 MW S-band (2856 MHZ) klystron tube and the matching 200 MW modulator. In order to obtain electron beam of the consequently stability for linac, the pulse-to-pulse beam voltage regulation is less than +/- 0.5 %. To get the reliable stability of the modulator which is less than +/- 0.5 %, a charging section is improved in a modulator which has been operated with inverter power supply.

Holstein 보증종모우 및 후보종모우의 선천성 장애 유전좌위 검색에 관한 연구

이연근,장길원,남인식,장원경,탁태영,김경남,이광전 한국동물자원과학회 2002 한국축산학회지 Vol.44 No.3

본 연구는 국내 홀스타인 젖소 보증종모우 16두와 후보종모우 93두를 이용하여 선청성 장애 유전자의 검색을 통하여 불량 유전자의 존재 유무를 판별함과 동시에 가축의 선발 및 육종, 개량시 기초자료로 제공하고자 하는데 그 목적이 있으며, 본 연구의 결과를 요약하면 아래와 같다. 공시재료(홀스타인 젖소 보증종모우 16두, 후보 종모우 93두) 109두에 대하여 DUMPS(deficiency of uridine monophophate synthase)의 검색결과 모든 개체에서 DUMPS 유전자를 보유하는 개체는 없는 것으로 판명되었다. 또한 PCR-RFLP(AvaⅠ) 방법에 의해 조기 검색이 가능하게 되었다. 한편, BLAD(bovine leukocyte adhesion deficiency) 검색결과, 보증종모우 16두에서는 검출되지 않았으나, 후보우 93두중 5두에서 BLAD 잠재성 보유개체(carrier)로 판명되었고, 혈통확인을 통하여 BLAD 유전자의 전이 경로를 추정할 수 있었으며, PCR 증폭산물에 대한 제한효소 처리시 HaeⅢ 보다는 TaqⅠ 제한효소를 사용하였을 때 더 효율적으로 판명할 수 있는 것으로 나타났다. Citrullinemia 검색결과 보증종모우 16두 및 후보종모우 93두 모두에서 잠재성 보유개체는 없는 것으로 판명되었으나 citrullinemia에 대한 폭넓고 다양한 조사 및 분석이 이루어져야 할 것으로 사료된다. 본 연구의 결과로 미루어 볼 때 가축의 유전성 질환에 대한 다양하고 폭넓은 연구가 이루어 져야 할 것으로 사료되며, 가축의 선발과 육종, 개량에 있어서 지속적이며 혈통의 철저한 관리를 통한 개량의 방향을 설정하여야 할 것으로 판명되었다. This study was performed to discriminate defective loci by detection of congenital genetic disorder, to offer basic data for selection and improvement of Korean dairy cattle using frozen semen of Holstein bulls(16 proven and 93 candidate). The results obtained were as follows ; By the detection of DUMP(deficiency of uridine monophophate synthase) for 109 Holstein bulls(16 proven and 93 candidate), DUMP carrier was not found in whole animals. Also, it was possible to early detection of DUMP carrier by using PCR-RFLP(AvaⅠ). As the results of detection for BLAD(bovine leukocyte adhesion deficiency), BLAD carrier was not found in 16 proven bulls. But 5 candidtae bulls are discriminated to BLAD carrier, and it could be predicted to transmitted pathway of inherited loci by pedigree identification. Also, when digesting PCR products using restriction enzyme, results from Taq Ⅰ restriction enzyme were more efficient than that of HaeⅢ. After detection test of citrullinaemia, it was concluded that proven and candidate bulls were not. However, wide range of research and citrullinaemia genotyping should be performed. As a result of this study, the wide and various research should be performed in genetic disease of animal. And in the selection and breeding of animal, the breeding scheme by completely and continuously management of pedigree should be established.

국내 분리 일본뇌염 바이러스 유전자에 대한 항체생성 연구(Ⅱ) : 일본뇌염 바이러스 유전자 발현 expression of JEV viral genes

주영란,최택균,유정희,이한샘,남재환,최우영,박근용,조해월 국립보건연구원 2000 국립보건원보 Vol.37 No.-

14.6 A GeV ^28Si 중이온이 원자핵건판내에서 발생시킨 핵반응에서 생성된 2차입자의 발생각 분포

김종오,김태연,남신우,신택수,우종관,이세병,임계엽,장세덕,조재희,천병구,임인택,김기영 慶尙大學校 기초과학연구소 1990 基礎科學硏究所報 Vol.6 No.-

14.6A GeV^28Si 중이온이 원자핵 건판내에서 발생시킨 N_h=1인 핵반응에서 생성된 47개의 파쇄 α 입자와 537개의 단일하전 2차입자의 발생각들을 측정하여 변수 exp(γ-η_b)의 포괄적 분포를 회귀함수 dN=exp[a+χ{exp(γ-η_b)d{exp(γ-η_b)}로 적합시켰다. 여기서 의사신속도 γ=arctanh(cosθ)=-ln tan(θ/2)이고, 입사 중이온의 신속도 η_b=3.445이다. 그 적합결과 파쇄 α입자의 경우 χ=-0.052±0.011이고, 파쇄 p입자의 경우 χ=-0.141±0.015이었다. For LS emission angles of 47 α fragments and 537 single-charged shower particles, produced by the N_h (the number of heavyprongs)=1 interactions of 14.6 A GeV^28Si nuclei in the nuclear emulsion, the distribution of the parameter exp(γ-η_b) is well expressed by dN=exp[a+χ{exp(γ-η_b)d{exp(γ-η_b)}with χ=-0.052±0.011 for αfragments and χ=-0.141±0.015 for p 'fragments', where the pseudorapidity of secondaries γ=arctanh(cosθ)=-ln tan(θ/2) and the rapidity of incident heavy ions, η_b=3.445.

High-Performance Blue InGaN Laser Diodes With Single-Quantum-Well Active Layers

Ryu, H.Y.,Haleem, K.H.,Lee, S.N.,Jang, T.,Son, J.K.,Paek, H.S.,Sung, Y.J.,Kim, H.K.,Kim, K.S.,O.H. Nam,Park, Y.J.,Shim, J.I. IEEE 2007 Photonics Technology Letters Vol.19 No.21

<P>The authors report on the high-performance blue laser diodes (LDs) with an emission wavelength of ~448 nm employing InGaN single-quantum-well (QW) active layers. At 100-mW continuous-wave (CW) output power, operation current and voltage are, respectively, 150 mA and 5.3 V, corresponding to the wall plug efficiency of >12%, a record value for the single-mode InGaN LDs with blue wavelengths. The single QW blue LD showed normal temperature dependence of light output-current curves with the characteristic temperature of 170 K. In addition, we demonstrate a high level of catastrophic optical damage of >300 mW and long device lifetime under CW operation condition at room temperature.</P>

Brillouin Light Scattering Study of the Magnetic Anisotropy in bcc-Fe(100) Ultrathin Films Grown on GaAs(100) Surfaces With Different Reconstructions

Seung-Seok Ha,Nam-Hee Kim,Chun-Yeol You,Sukmock Lee,Ohta, K.,Maruyama, T.,Konishi, K.,Nozaki, T.,Suzuki, Y.,Van Roy, W. IEEE 2009 IEEE transactions on magnetics Vol.45 No.6

<P>We investigated the magnetic anisotropy of ultrathin bcc-Fe (001) films with a fcc-Au(001) cover layer, grown onto GaAs (001) (4 times 1) and (2 times 6)/(3 times 6) reconstructed surfaces. The magneto-optical Kerr effect hysteresis loops revealed existence of a strong in-plane uniaxial magnetic anisotropy in the Fe films grown on both the surfaces. Details of the in-plane uniaxial anisotropy (K<SUB>U</SUB>), cubic anisotropy (K<SUB>C</SUB>), and effective demagnetization field (4piM<SUB>eff</SUB>) were studied by Brillouin light scattering method. We observed a stronger reduction of K<SUB>U</SUB>, K<SUB>C</SUB>, and 4piM<SUB>eff</SUB> in thinner Fe layers (below 1.3 nm) grown on both the surfaces. In the case of Fe films grown on GaAs (4 times 1) surface, anisotropies observed were smaller than that for the (2 times 6)/(3 times 6) surface. This reflects the role of surface structure in determining the magnetic anisotropies.</P>