Distinction of Landslide by Monitoring Acceleration to Autonomous Node In Wireless Sensing Network

Yasutaka Nakajima,Riki Ohbayashi,Shigeru Takayama 제어로봇시스템학회 2009 제어로봇시스템학회 국제학술대회 논문집 Vol.2009 No.8

For monitoring natural landslide disaster, wireless sensing node network is so effective system. The sensingnode is constructed by some sensors (acceleration, soil moisture, GPS and so on), data processing unit (micro processor)and wireless communication unit. The network topology we have constructed is mesh type. In the system, at sensinglandslide, the node will transport the information to host system through the node network by using wirelesscommunication. Generally, in natural field, the landslide is sensed as the changing of acceleration. But, it is sodifficult to distinguish the landslide obviously. The acceleration of the sensing node will change by not only thelandslide disaster but also collision with several hard blocks like stones. This paper describes the distinction method oflandslide disaster by using only the signal of acceleration sensor mounted in the sensing node. The method focuses thetime transition of frequency distribution of the acceleration signal. Observing the time transition, the situations ofsensing node have been distinguished.

Capability of Pulse-Doped GaAs MESFETs as Active Devices for Satellite Communications

Nobuo Shiga,Shigeru Nakajima,Kenji Otobe,Takeshi Sekiguchi,Nobuhiro Kuwata,Ken-ichiro Matsuzaki,Hideki Hayashi 대한전자공학회 1990 JC-CNSS : Joint Conference on Communications, Netw Vol.3 No.-

Significance of PD-L1 expression in carbon-ion radiotherapy for uterine cervical adeno/adenosquamous carcinoma

Moito Iijima,Noriyuki Okonogi,Nakako Izumi Nakajima,Yukie Morokoshi,Hiroaki Kanda,Taiju Yamada,Yusuke Kobayashi,Kouji Banno,Masaru Wakatsuki,Shigeru Yamada,Tadashi Kamada,Daisuke Aoki,Sumitaka Hasegaw 대한부인종양학회 2020 Journal of Gynecologic Oncology Vol.31 No.2

Objective: Programmed cell death-ligand 1 (PD-L1) is expressed in tumor cells and has been shown to predict clinical outcomes of several types of malignancies. The aim of this study was to investigate the effects of carbon-ion (C-ion) beam irradiation on PD-L1 expression in human uterine cervical adeno/adenosquamous carcinoma (UCAA) cells and clinical samples and to identify the prognostic factors for outcomes after C-ion radiotherapy (CIRT). Methods: The effects of C-ion irradiation on PD-L1 expression in human UCAA and cervical squamous cell carcinoma cells were examined by flow cytometry. We examined PD-L1 expression in UCAA biopsy specimens from 33 patients before CIRT started (pre-CIRT) and after 12 Gy (relative biological effectiveness [RBE]) irradiation (post-12Gy-C) in 4 fractions of CIRT to investigate the correlation between PD-L1 status and clinical outcomes. Results: The PD-L1 expression was upregulated by C-ion beam in a dose-dependent manner in HeLa and SiHa cells through phosphorylated Chk1. The overall frequencies of pre-CIRT and post-12Gy-C PD-L1 positivity were 45% (15/33) and 67% (22/33), respectively. The post-12Gy-C PD-L1 expression was significantly elevated compared to the pre-CIRT PD-L1 expression. There was no significant relationship between the pre-CIRT PD-L1 status and clinical outcomes, such as local control (LC), progression-free survival (PFS), and overall survival (OS). However, the post-12Gy-C PD-L1 expression had better correlation with PFS, but not with LC and OS. Conclusion: CIRT can induce PD-L1 expression in UCAA and we propose that PD-L1 expression after starting CIRT may become as a predictive prognostic marker in CIRT for UCAA.

Induction of apoptotic lesions in liver and lymphoid tissues and modulation of cytokine mRNA expression by acute exposure to deoxynivalenol in piglets

Osamu Mikami,Hiroyuki Yamaguchi,Hideo Murata,Yasuyuki Nakajima,Shigeru Miyazaki 대한수의학회 2010 Journal of Veterinary Science Vol.11 No.2

Six 1-month-old piglets were intravenously injected with deoxynivalenol (DON) at the concentration of 1 mg/kg body weight, with three pigs each necropsied at 6 and 24 h post-injection (PI) for investigation of hepatotoxicity and immunotoxicity with special attention to apoptotic changes and cytokine mRNA expression. Histopathological examination of the DON-injected pigs revealed systemic apoptosis of lymphocytes in lymphoid tissues and hepatocytes. Apoptosis of lymphocytes and hepatocytes was confirmed by the TdT-mediated dUTP-biotin nick end-labeling (TUNEL) method and immunohistochemical staining against singlestranded DNA and cleaved caspase-3. The number of TUNELpositive cells in the thymus and Peyer’s patches of the ileum was increased at 24 h PI compared to 6 h PI, but the peak was at 6 h PI in the liver. The mRNA expression of interleukin (IL)-1β, IL-6, IL-18, and tumor necrosis factor (TNF)-α in the spleen, thymus and mesenteric lymph nodes were determined by semi-quantitative RT-PCR, and elevated expression of IL-1β mRNA at 6 h PI and a decrease of IL-18 mRNA at 24 h PI were observed in the spleen. IL-1β and IL-6 mRNA expressions increased significantly at 6 h PI in the thymus, but TNF-α decreased at 6 h PI in the mesenteric lymph nodes. These results show the apoptosis of hepatocytes suggesting the hepatotoxic potential of DON, in addition to an immunotoxic effect on the modulation of proinflammatory cytokine genes in lymphoid organs with extensive apoptosis of lymphocytes induced by acute exposure to DON in pigs.

Suppressed Fat Accumulation in Rats Fed a Histidine-Enriched Diet

Michiko Endo,Seiichi Kasaoka,Miki Takizawa,Kiyoko Goto,Shigeru Nakajima,Soo-Kyung Moon,In-Soo Kim,Bo-Young Jeong,Soichiro Nakamura 한국식품영양과학회 2010 Preventive Nutrition and Food Science Vol.15 No.1

The effect on body fat accumulation on male Wistar rats undergoing continuous feeding with a histidine-enriched diet was investigated. Five-week-age rats were assigned to two groups and were fed either the control diet (purified diet AIN-76™) or the histidine-enriched diet containing 3% histidine for 28 days. It was observed that both adipose tissue masses in retroperitoneal and epididymal areas of rats fed histidine-enriched diet significantly decreased (p<0.05) compared to those of control rats, while there was no significant difference in the food efficiency ratio between them. The blood levels of histidine derivatives of 3-methylhistidine and carnosine were significantly (p<0.05) increased in the rats fed a histidine-enriched diet, whereas there were no significant different between the histidine-enriched diet and control groups in the general amino acid distribution. Our results demonstrate that a histidine-enriched diet suppresses body fat accumulation in rats.

Suppressed Fat Accumulation in Rats Fed a Histidine-Enriched Diet

Endo, Michiko,Kasaoka, Seiichi,Takizawa, Miki,Goto, Kiyoko,Nakajima, Shigeru,Moon, Soo-Kyung,Kim, In-Soo,Jeong, Bo-Young,Nakamura, Soichiro The Korean Society of Food Science and Nutrition 2010 Preventive Nutrition and Food Science Vol.15 No.1

The effect on body fat accumulation on male Wistar rats undergoing continuous feeding with a histidine-enriched diet was investigated. Five-week-age rats were assigned to two groups and were fed either the control diet (purified diet AIN-$76^{TM}$) or the histidine-enriched diet containing 3% histidine for 28 days. It was observed that both adipose tissue masses in retroperitoneal and epididymal areas of rats fed histidine-enriched diet significantly decreased (p<0.05) compared to those of control rats, while there was no significant difference in the food efficiency ratio between them. The blood levels of histidine derivatives of 3-methylhistidine and carnosine were significantly (p<0.05) increased in the rats fed a histidine-enriched diet, whereas there were no significant different between the histidine-enriched diet and control groups in the general amino acid distribution. Our results demonstrate that a histidine-enriched diet suppresses body fat accumulation in rats.

한ㆍ일 일부지역 여대생의 식습관과 식품기호도 비교

이경애(Kyoung Ae Lee),정보영(Bo-Young Jeong),문수경(Soo-Kyung Moon),김인수(In-Soo Kim),Nakajima Shigeru,Nakamura Soichiro 한국식품영양과학회 2010 한국식품영양과학회지 Vol.39 No.11

본 연구는 한국과 일본의 일부지역 여대생들을 대상으로 식습관과 식품기호도를 조사?비교함으로써 우리나라 여대생들의 식생활 실태를 대외적 차원에서 파악하고자 하였으며 결과를 요약하면 다음과 같다. 한국여대생은 일본여대생에 비해 체중에는 차이가 없었으나 신장이 더 커서 BMI는 더 적었다. 한국여대생은 일본여대생보다 밥식과 된장국 섭취횟수는 많았으나 아침 결식과 외식 횟수는 2배 이상 높았고 패스트푸드, 인스턴트식품, 냉동식품의 섭취 횟수가 높아 식습관이 바람직하지 못하였으며 활동 정도도 낮았다. 양국 대학생들은 모두 생선류보다는 육류와 우유 및 유제품에 대한 기호도가 높아 식생활의 서구화 경향을 보였고 채소류보다는 과일류에 대한 기호도가 높아 단맛에 대한 기호를 나타내었다. 한국여대생은 일본여대생과 비교하여 육류에 대한 기호도에는 차이가 없었으나 곡류, 생선류, 콩 및 콩제품, 채소류, 김을 제외한 해조류에 대한 기호도가 낮았으며 반면에 우유와 요구르트에 대한 기호도는 높았다. 결론적으로 한국여대생은 일본여대생에 비해 아침 결식, 외식, 패스트푸드, 인스턴트식품, 냉동식품의 섭취 횟수가 높아 바람직하지 못한 식습관을 지니고 있었고 식품기호도에서도 섭취를 권장하는 생선류, 콩 및 콩제품, 채소류, 해조류에 대한 기호도가 낮아 전반적으로 바람직하지 못한 식생활실태를 보였으며 더욱이 활동 정도까지 낮아 일본여대생보다 장차 식생활과 관련한 질병 유발 가능성을 더 많이 내포하고 있었다. 따라서 여대생 자신의 건강과 미래의 가정과 사회를 이끌 그들의 위치를 고려하여 우리나라 여대생들이 이러한 자신들의 실태를 자각하고 식습관을 바르게 교정하여 바람직한 식생활을 할 수 있도록 이와 관련한 교육이 절실히 요구된다. This study was conducted to compare eating habits and food preferences of Korean and Japanese female college students in some areas of the two countries. The subjects were 365 Korean students and 313 Japanese students. The survey was done in every May for three years from 2006 to 2008. Eating habits and food preferences were investigated by questionnaire. The results were as follows. There was no significant difference in body weight, but Korean students were taller and they ate out more frequently than Japanese students. Both Korean students and Japanese students liked meat, milk and milk products better than fishes. Also, they liked fruits better than vegetables. Korean students had lower preferences for fish, beans and bean products, vegetables, and seaweed than Japanese students. In conclusion, Korean students seem to be exposed to risk factors to health more than Japanese students, because they had less desirable eating habits and food preferences, and were less active than Japanese students. Therefore Korean students might need to change their eating habits and food preferences into more desirable ones for their good health.