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김도현,박무인,유찬희,김규종,문원,박선자,장희경 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.2
저자들은 65세 남자 환자의 위 중부체부 대만부 전벽에 발생한 점막하 종양에 대하여 3년간 추적관찰 중 크기증가소견으로 쐐기 절재술을 시행하였으며, 조직검사 및 면역 조직 화학 검사에서 위 신경초종으로 진단한 1예를 경험하였기에 보고하는 바이다. Gastric schwannoma is a very rare gastrointestinal benign tumor, which represents only 0.2% of all gastric tumors and 4% of all benign gastric tumors. We report a case of gastric schwannoma with enlargement of size through serial endoscopic examination. Endoscopic examination showed a hard mass of 4 x 3 cm in size with normal overlying gastric mucosa on the great curvature of the mid-body of stomach. The pathological finding revealed a picture of spindle cell tumor. Immunohistochemical stain was strongly positive for S-100 protein and non-reactive for CD34, C-kit and smooth muscle actin, thus leading to the diagnosis of gastric schwannoma.
인체 간 Microsome에서의 우슬 추출물의 Cytochrome P450 약물 대사효소에 대한 억제작용
김경아,이지숙,박히준,김진우,김창주,심인섭,한승무,임사비나 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2003 東西醫學硏究所 論文集 Vol.2003 No.-
Objective : Achyranthes bidentata radix (Usul) has been used as anti-arthritic, antiallergic, antidiuretic and so on Recently extracts of Achyranthes bidentata radix have shown anti-inflammatory and cancer preventive effects in vitro and in vivo. Methods : We therefore evaluated the inhibitory potential of ehtanol extracts of Achyranthes bidentata radix on cytochrome P450(CYP) isoforms-catalyzecd reactions, which relate to causes of cancer and inflammation, including CYP1A2, CYP2C9, CYP2C19, CYP2E1, CYP2D6, CYP2C8, and CYP3A4, using human liver microsomal preparations. Results : The extracts showed weak or negligible inhibitory effects on CYP2C9-catalyzed (S)-warfarin 7-hydroxylation, CYP2C19-catalyzed S-mephenytoin 4-hydroxylation, and CYP2D6-catalyzed dextromethorphan O-demethylation with each IC50 over 1750 g/㎖, respectively. However, it showed relatively significant inhibitory effect on CYP1A2-catalyzed phenacetin O-deethylation and CYP2E1-catalyzed chloizoxazone 6-hydroxylation with IC50s of 970.5 g/㎖ and 821.4 g/㎖, respectively. Conclusions : These results suggest that extracts of Achyranthes bidentata radix have inhibitory effects on CYP-catalyzed reactions, expeciallyCYP1A2 and CYP2E1, in human liver microsomes. These effects appear to relate to anti-inflammatory and cancer prevention following decrease of reactive oxygen species formed by CYP, especially CYP1A2 and CYP2E1, by Achyranthes bidentata radix. However, further evaluation is necessary to demonstrate and to confirm its effects in human.
The Effect of Sa-am acupuncture on Knee Osteoarthritis
( Moo Hong Min ),( Yeong Gon Choi ),( Yun Ju Kim ),( Hi Joon Park ),( Sam Chool Lee ),( Ho No Joo ),( Seung Moo Han ),( Sa Bi Na Lim ) 대한경락경혈학회 2009 Korean Journal of Acupuncture Vol.26 No.4
Objective: Acupuncture has been widely used throughout the world for the treatment of knee osteoarthritis (knee OA). This study investigated whether acupuncture, particularly Sa-am acupuncture, could be effective in relieving pain and improving the symptoms of knee OA. Method: This study was conducted as a prospective, randomized, controlled, and patient- and investigator- blinded clinical trial. Forty volunteers with knee OA participated in the study. All participants were screened through an inclusion and exclusion criteria. Thirty four participants completed the clinical trial. In total, forty subjects were randomly selected to receive Sa-am acupuncture. Eight sessions of acupuncture were given at the contralateral side of the problematic knee for 4 weeks. Korean translation of Western Ontario and McMaster Universities Osteoarthritis Index (KWOMAC) scores were measured twice: at the beginning and end of the clinical trial period. Both the Patient Global Assessment and physical health scores based on the 36-Item Short-Form Health Survey were also used to measure the results. Results: Compared to the pre-trial scores, the Sa-am acupuncture group (n=34) showed a significant decrease in KWOMAC total scores according to a paired t -test. The Sa-am acupuncture group also showed significant improvement in the Patient Global Assessment when compared to the pre-trial. Conclusions: Sa-am acupuncture for knee OA resulted in an improved KWOMAC total score. This was mostly driven by the function component score that was greatly affected by acupuncture. However, further studies with expanded designs are needed to solidify this finding with scientific rigor.
The Effect of Sa-am acupuncture on Knee Osteoarthritis
Min, Moo-Hong,Choi, Yeong-Gon,Kim, Yun-Ju,Park, Hi-Joon,Lee, Sam-Chool,Joo, Ho-No,Han, Seung-Moo,Lim, Sa-Bi-Na Society for Meridian and Acupoint 2009 Korean Journal of Acupuncture Vol.22 No.1
Objective : Acupuncture has been widely used throughout the world for the treatment of knee osteoarthritis (knee OA). This study investigated whether acupuncture, particularly Sa-am acupuncture, could be effective in relieving pain and improving the symptoms of knee OA. Method : This study was conducted as a prospective, randomized, controlled, and patient- and investigator-blinded clinical trial. Forty volunteers with knee OA participated in the study. All participants were screened through an inclusion and exclusion criteria. Thirty four participants completed the clinical trial. In total, forty subjects were randomly selected to receive Sa-am acupuncture. Eight sessions of acupuncture were given at the contralateral side of the problematic knee for 4 weeks. Korean translation of Western Ontario and McMaster Universities Osteoarthritis Index (KWOMAC) scores were measured twice: at the beginning and end of the clinical trial period. Both the Patient Global Assessment and physical health scores based on the 36-Item Short-Form Health Survey were also used to measure the results. Results : Compared to the pre-trial scores, the Sa-am acupuncture group (n=34) showed a significant decrease in KWOMAC total scores according to a paired t-test. The Sa-am acupuncture group also showed significant improvement in the Patient Global Assessment when compared to the pre-trial. Conclusions : Sa-am acupuncture for knee OA resulted in an improved KWOMAC total score. This was mostly driven by the function component score that was greatly affected by acupuncture. However, further studies with expanded designs are needed to solidify this finding with scientific rigor.
Melting of Ice on the Heating Plate with Split Fins
Hong, Hi-Ki,Kim, Moo-Geun The Society of Air-Conditioning and Refrigerating 2001 International Journal Of Air-Conditioning and Refr Vol.9 No.2
One of the important applications of a contact melting process is a latent thermal energy storage system owing to its high heat flux and small temperature variation. In some previous works, the split fins have been employed in order to enhance the melting rate. In the present work, the direct contact melting was experimentally investigated using an ice as specimen for both split and non-split fins. It was shown that the contact melting by split fins increases the melting rate compared to that of non-split ones.
李茂洛,姜淙熙 慶北工業專門大學 1979 論文集 Vol.16 No.-
Today according to the increase of construction works, land development plan was spured on the development of industrialbase of burying sea and streams. And according to the demand of large-sized structures and rapid constrection-works, evaporation-method and liquid chemicals instillment has been developed as the improvement method of soft ground. As the response of such demand, uria-risim, cement, poly sodiumacrglate, water glass, etd. are produced and the studo on each chararacteristics is continuing. In this paper urea resin primari-condensation product, and polymer was used with hardener. As a result, causing polymerization or crosslinking reaction in soil, net-work poly makes coagulation and adhesion consist soil particles. In this experiment NH₄Cl was used as hardener of urea resin primari-condensation product. This method is now performed to know whether hardening of NH₄Clis superior of other kind of salt or not. Each of salts used for this experiment-NH₄Cl and Al₂(SO₄)₃were arranged to urea resin promaries-condensation product, and then hydrochloric acid of fixed quantity was added to it as hardener-promotor. In the experiment of intensity, testing method for unconfined compressive strength cohesive soils was performed, and then the capacity of stablizer of soils and the effect for hardner were examined comparatively.
Yeoul Hi Lee(李烈熙),Gi Jung Byun(卞基禎),Suk Hwan Klm(金錫煥),Kyoung Woo Lee(李庚雨),Jae Yeoun Kim(金在淵),Moo Jung Kim(金茂中) 대한구강악안면외과학회 1979 대한구강악안면외과학회지 Vol.5 No.1
We made a repart of rarity about a papilloma s size and our various experiences during treatment. The result for the treatment of a papilloma in an epithelial origin on hard palate was as following; ① A papilloma on hard palate can recur easily, if 1t will not be excised radically. ② When a papilloma recur, increase of the size of a papilloma is very rapid ③ It is considered that a papilloma on hard palate is produced by chronic irritation of maxillary anterior restoration as Kruger s report. ④ When radical excision with mucoperosteal flap was performed, saucer-like bony invasion of hard palate was noticed, the result of biopsy by curetting the bone surface showed normal osseous and fibrous connective tissue.