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Kim, Moo-Sub,Kubo, Kazuki,Monzen, Hajime,Yoon, Do-Kun,Shin, Han-Back,Kim, Sunmi,Suh, Tae Suk Korean Society of Medical Physics 2016 의학물리 Vol.27 No.4
The purpose of this study is to develop the treatment planning system (TPS) based on Monte-Carlo simulation for BNCT. In this paper, we will propose a method for dose estimation by Monte-Carlo simulation using the CT image, and will evaluate the accuracy of dose estimation of this TPS. The complicated geometry like a human body allows defining using the lattice function in MCNPX. The results of simulation such as flux or energy deposition averaged over a cell, can be obtained using the features of the tally provided by MCNPX. To assess the dose distribution and therapeutic effect, dose distribution was displayed on the CT image, and dose volume histogram (DVH) was employed in our developed system. The therapeutic effect can be efficiently evaluated by these evaluation tool. Our developed TPS could be effectively performed creating the voxel model from CT image, the estimation of each dose component, and evaluation of the BNCT plan.
Reference based simulation study of detector comparison for BNCT-SPECT imaging
Kim, Moo-Sub,Shin, Han-Back,Choi, Min-Geon,Monzen, Hajime,Shim, Jae Goo,Suh, Tae Suk,Yoon, Do-Kun Korean Nuclear Society 2020 Nuclear Engineering and Technology Vol.52 No.1
To investigate the optimal detector material for prompt gamma imaging during boron neutron capture therapy, in this study, we evaluated the characteristic regarding radiation reaction of available detector materials using a Monte Carlo simulation. Sixteen detector materials used for radiation detection were investigated to assess their advantages and drawbacks. The estimations used previous experimental data to build the simulation codes. The energy resolution and detection efficiency of each material was investigated, and prompt gamma images during BNCT simulation were acquired using only the detectors that showed good performance in our preliminary data. From the simulation, we could evaluate the majority of detector materials in BNCT and also could acquire a prompt gamma image using the six high ranked-detector materials and lutetium yttrium oxyorthosilicate. We provide a strategy to select an optimal detector material for the prompt gamma imaging during BNCT with three conclusions.
Yuichi Onishi,Shinichi Nakayama,Shinsaku Watanabe,Souichirou Kaneshige,Hajime Monzen,Kenji Matsumoto,Naoya Shintani,Takeshi Kamomae 한국물리학회 2015 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.67 No.1
We constructed seven intensity-modulated radiation therapy (IMRT) treatment plans for prostate cancer (49 irradiation fields which contained seven randomly-sampled patients and seven fields) and evaluated the dose distributions by using a radiochromic film (EBT3 film) and a 2D detector. We superposed the calculated dose distribution of the IMRT treatment plan on EBT3 film and the 2D detector results and then compared those with the -analysis pass rate. The relative positions of the beam and the detector were varied; the results of the analysis of the superior-inferior (SI) direction potentially differed, depending on the detector position, under an irradiation beam with the same fluence map. The detector was moved over a range of ±8 mm in the SI direction in 1-mm step increments, measurement were made at each position, and the results were analyzed. The -analysis compared the dose distributions from EBT3 film and the radiation treatment planning system (RTPS) for each patient and field; the pass rate with the -analysis from 98 to 100% was 2.04%. When we compared the dose distributions of the 2D detector and the RTPS, the pass rate from 98 to 100% was 63.2%. The mean values for the -analysis pass rates for EBT3 film and the 2D detector were 94.2 and 97.6%, respectively. Volume averaging of the data indicated a mean pass rate and standard deviation of 98.6 and 0.91%, respectively, and a pass rate of more than 96% for all positions. A 2D detector can, therefore, be used as an alternative apparatus for IMRT dose verification.
Immunological Enhancement by Echinacea purpurea of An Ingredient Fraction
Yeunhwa Gu,Takenori Yamashita,Takashi Nakamura,Kiyoto Saito,Hajime Monzen,Masami Oshima,Eunsuk Choi,Daigo Matsumoto,Ikukatsu Suzuki,Kyoo Seok Ahn,Tetsuo Takeuchi,Satoshi Mishima,Yuicti Mituhana,Kenich 한의병리학회 2004 대한동의병리학회 학술대회논문집 Vol.2004 No.8
Anti-Cancer and Radiation Protection Effects by Ganoderma Lucidum
Yeunhwa Gu,Kouri Ryutarou,Takashi Nakamura,Kenichiro Tanaka,Masayuki Tajima,Takenori Yamashita,Hiroaki Tanabe,Daigo Matsumoto,Hajime Monzen,Masami Oshima,Eunsuk Choi,Ikukatsu Suzuki,Kyoo Seok Ahn,Tets 한의병리학회 2004 대한동의병리학회 학술대회논문집 Vol.2004 No.8
Anti-Tumor effect and Immunological Enhancement in Fuscoporia obliqua
Yeunhwa Gu,Kenichiro Tanaka,Takashi Nakamura,Masayuki Tajima,Takenori Yamashita,Takeo Hasegawa,Kaoru Terai,Hiroyuki Iwasa,Hajime Monzen,Masami Oshima,Eunsuk Choi,Kyoo Seok Ahn,Tetsuo Takeuchi,Mituhana 한의병리학회 2004 대한동의병리학회 학술대회논문집 Vol.2004 No.8
Anti-Tumor effect and Immunological Enhancement in Fuscoporia obliqua
Yeunhwa Gu,Kenichiro Tanaka,Tankashi Nakamura,Masayuki Tajima,Takenori Yamashita,Takeo Hasegawa,Kaoru Terai,Hiroyuki Iwasa,Hajime Monzen,Masami Oshima,Eunsuk Choi,Kyoo Seok Ahn,Tetsuo Takeuchi,Mituhan 한의병리학회 2004 대한동의병리학회 학술대회논문집 Vol.2004 No.8
Anti-Cancer and Radiation Protection Effects by Ganoderma Lucidum
Yeunhwa Gu,Kouri Ryutarou,Takashi Nakamura,Kenichiro Tanaka,Masayuki Tajima,Takenori Yamashita,Hiroaki Tanabe,Daigo Matsumoto,Hajime Monzen,Masami Oshima,Eunsuk Choi,Ikukatsu Suzuki,Kyoo Seok Ahn,Tets 한의병리학회 2004 대한동의병리학회 학술대회논문집 Vol.2004 No.8