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Immune activation and radioprotection by Echinacea purpurea (American herb)
Mishima, Satoshi,Gu, Yeun-Hwa,Saito, Kiyoto,Yamashita, Takenori,Maruyama, Hiroe,Inoue, Makoto,Ahn, Kyoo-Seok Kyung Hee Oriental Medicine Research Center 2004 Oriental pharmacy and experimental medicine Vol.4 No.3
The effect of immune activation by Echinacea purpurea was investigated by measuring total immunoglobulin (Ig) G, IgM. and the radioprotective effect of immune activation by Echinacea purpurea was investigated by measuring T lymphocyte subsets in the peripheral blood of mice following whole body irradiation. Echinacea purpurea activated macrophages to stimulate $IFN-{\gamma}$ production in association with the secondary activation of T lymphocytes, resulting in a decrease in IgG and IgM production. Cytokines released from macrophages in mouse peripheral blood after Echinacea purpurea administration activated helper T cells to proliferate. In addition, activated macrophages in association with the secondary T lymphocyte activation increased $IFN-{\gamma}$ production and stimulated proliferation of cytotoxic T cells and suppressor T cells, indicating the activation of cell-mediated immune responses.
Immunological Enhancement by Echinacea purpurea of An Ingredient Fraction
Yeunhwa Gu,Takenori Yamashita,Takashi Nakamura,Kiyoto Saito,Hajime Monzen,Masami Oshima,Eunsuk Choi,Daigo Matsumoto,Ikukatsu Suzuki,Kyoo Seok Ahn,Tetsuo Takeuchi,Satoshi Mishima,Yuicti Mituhana,Kenich 한의병리학회 2004 대한동의병리학회 학술대회논문집 Vol.2004 No.8