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Expression of translationally controlled tumor protein mRNA in human colon cancer
Chung, Sookhee,Kim, Miyoung,Choi, Won-Ja,Chung, June-Key,Lee, Kyunglim 梨花女子大學校 藥學硏究所 2000 藥學硏究論文集 Vol.- No.9
The translationally controlled tumor protein (TCTP) was first identified as a tumor-associated protein. Here we described the expression profile of TCTP mRNA using a panel of normal human tissues. We also investigated the cell-cycle-dependence expression of the TCTP mRNA using synchronized cultures of Saccahromyces cerevisiae. The TCTP gene was constantly expressed through the yeast cell cycle. The expression of TCTP mRNA from three human colon carcinoma cell lines and the tumors xenografted in a nude mouse was studied. Our data imply that the TCTP is a housekeeping gene and that its deregulation may be involved in the tumor development of colon carcinoma.
대학생의 인터넷 중독위험 정도에 따른 사회 심리적 건강
정미영(Miyoung Chung),조옥희(Ok-Hee Cho) 한국콘텐츠학회 2013 한국콘텐츠학회논문지 Vol.13 No.5
본 연구는 749명의 대학생을 대상으로 인터넷 중독위험 정도에 따른 사회 심리적 건강상태를 파악하고 중독위험에 영향을 미치는 요인을 규명하기 위하여 시행되었다. 인터넷 중독위험 정도는 The 6th Korea Youth Risk Behavior Web-based Survey의 인터넷 중독 자가진단 척도로 측정하여 중독위험 사용자군, 정상 사용자군으로 분류하였고 각 군의 사회 심리적 건강상태는 절망감, 자살생각, 자살시도, 생활스트레스, 사회적 고립감, 정신건강 점수를 측정하여 비교하였다. 인터넷 정상 사용자군 및 중독위험 사용자군의 일반적 특성과 인터넷 중독위험 정도, 사회 심리적 건강은 t-test와 x2-test로 비교 분석하였고, 인터넷 중독위험 에 영향을 미치는 요인은 logistic regression analysis로 확인하였다. 연구결과 중독위험 사용자군은 82명(10.9%), 정상 사용자군은 667명(89.1%)이었고 절망감, 자살시도 경험, 생활스트레스, 사회적 고립감, 정신건강 점수에서 중독위험 사용자 군이 정상사용자군에 비해 빈도 및 점수가 유의하게 높아 사회 심리적 건강상태가 불량한 것으로 나타났다. 이상의 결과는 인터넷 중독사용 고위험 군을 조기선별하고 인터넷 중독 발생을 예방하며 나아가 이들을 위한 심리사회적 건강을 증진시키기 위한 프로그램 개발의 기초자료로 활용될 것을 기대한다. This study aimed to compare Psycho-social Well-being depending on level of internet addiction and investigate the factors inducing internet addiction among 749 college students. The Internet Addiction Diagnosis Criterion Inventory was used to classify participants into two groups, Internet overuse and Internet normal use. The psychosocial well-being of each group was measured by hopelessness, idea of suicide, suicide attempt, stress, social isolation, and mental health. Data were analyzed using the t-test and x2-test to compare general characteristics, level of internet addiction and psycho-social well-being between two groups(the overuse and normal use group). Moreover, logistic regression analysis was used to examine the factors inducing internet addiction. The results placed 82 people (10.9%) in the internet overuse group and 667 people(89.1%) in the internet normal use group. The internet overuse group showed higher level of hopelessness, idea of suicide, suicide attempt, stress, social isolation, and mental health scores than the internet normal use group. Therefore, people in the internet overuse group were more likely to have worse Psycho-social well-being. The results of this study recommend that the Internet overuse should be screened early because it can be useful in developing addiction prevention programs and then finally improving the psycho-social well-being.
Clinical practice guidelines for percutaneous endoscopic gastrostomy
Chung Hyun Tae,Ju Yup Lee,Moon Kyung Joo,Chan Hyuk Park,Eun Jeong Gong,Cheol Min Shin,Hyun Lim,Hyuk Soon Choi,Miyoung Choi,Sang Hoon Kim,Chul-Hyun Lim,Jeong-Sik Byeon,Ki-Nam Shim,Geun Am Song,Moon Sun 대한소화기내시경학회 2023 Clinical Endoscopy Vol.56 No.4
With an aging population, the number of patients with difficulty in swallowing due to medical conditions is gradually increasing. In such cases, enteral nutrition is administered through a temporary nasogastric tube. However, the long-term use of a nasogastric tube leads to various complications and a decreased quality of life. Percutaneous endoscopic gastrostomy (PEG) is the percutaneous placement of a tube into the stomach that is aided endoscopically and may be an alternative to a nasogastric tube when enteral nutritional is required for four weeks or more. This paper is the first Korean clinical guideline for PEG developed jointly by the Korean College of Helicobacter and Upper Gastrointestinal Research and led by the Korean Society of Gastrointestinal Endoscopy. These guidelines aimed to provide physicians, including endoscopists, with the indications, use of prophylactic antibiotics, timing of enteric nutrition, tube placement methods, complications, replacement, and tube removal for PEG based on the currently available clinical evidence.
Transferable single-crystal GaN thin films grown on chemical vapor-deposited hexagonal BN sheets
Chung, Kunook,Oh, Hongseok,Jo, Janghyun,Lee, Keundong,Kim, Miyoung,Yi, Gyu-Chul Nature Publishing Group 2017 NPG Asia Materials Vol.9 No.7
<P>Single-crystal gallium nitride (GaN) layers were directly grown on centimeter-scale hexagonal boron nitride (h-BN). Using chemical vapor deposition (CVD), centimeter-scale h-BN films were synthesized on a single-crystal Ni(111) and readily transferred onto amorphous fused silica supporting substrates that had no epitaxial relationship with GaN. For growing fully coalescent GaN layers on h-BN, the achievement of high-density crystal growths was a critical growth step because the sp(2)-bonded h-BN layers are known to be free of dangling bonds. Unlike GaN layers grown on a typical heterogeneous sapphire substrate, the morphological and microstructural results strongly suggest a high-density growth feature that is driven by the atomic cliffs inherent in the CVD-grown h-BN layers. More importantly, the GaN layers grown on CVD-grown h-BN exhibited a flat and continuous surface morphology with well-aligned crystal orientations both along the c-axis and in-plane, indicating the characteristics of GaN heteroepitaxy on h-BN.</P>
케냐의 지속가능한 모자보건 증진을 위한 감염병 퇴치 도전과 성과
박미영(Miyoung Park),정명애(Myung-Ae Chung),안경숙(Kyungsook Ahn) 적정기술학회 2022 적정기술학회지(Journal of Appropriate Technology) Vol.8 No.3
케냐에서는 임산부 무상 케어 프로그램인 ‘린다 마마 프로그램’을 시행하고 있지만, 2017년 기준 출생아 10만 명 당 임산부 사망률이 342에 달하며 에이즈, B형 간염, 매독 등 감염률이 높은 상황이다. 신속간이검사(래피드진단)를 중심으로 진단이 이루어지고 있으나 정확도가 떨어지고 있어, 정확하고 신속한 진단 방법이 필요하다. 이에 한국국제협력단(KOICA)의 혁신적 기술 프로그램(CTS)을 통해 병원 이외에 학교, 지역 보건소 등에서 최소 교육으로도 검사가 가능한 에이즈, B형 간염, 매독을 진단할 수 있는 다중면역진단기기 및 다중진단키트를 개발하였다. 진단키트의 민감도 및 특이도는 각 90% 이상으로 나타났으며 이는 신속진단키트 대비 20% 이상 향상된 것이다. 가격경쟁력을 갖춘 진단기기와 키트 보급으로 15세 이상 49세 이하 가임여성들의 에이즈, B형 간염, 매독 감염에 대한 지속적인 모니터링이 가능해짐으로서 모자 보건 증진에 기여할 수 있을 것이다. In Kenya, the ‘Linda Mama Program’, a free care program for pregnant women, is being implemented, but as of 2017, maternal deaths per 100,000 live births reached 342, and the infection rate such as AIDS, hepatitis B, and syphilis is high. Diagnosis is being made centering on a quick simple test (rapid diagnosis), but the reliability is low, so an accurate and quick diagnosis method is needed. Through the Innovative Technology Program (CTS) of Korea International Cooperation Agency (KOICA), we developed a multi-immune diagnostic device and multi-diagnostic kit that can diagnose AIDS, hepatitis B, and syphilis, which can be tested with minimal education at schools and local public health centers in addition to hospitals. The sensitivity and specificity of the diagnostic kit were each 90% or more, which was improved by more than 20% compared to the rapid diagnostic kits. The supply of cost-competitive diagnostic devices and test kits will enable continuous monitoring of AIDS, hepatitis B, and syphilis infections among women of childbearing age between the ages of 15 and 49, thereby contributing to the improvement of maternal and child health.
Clinical Practice Guideline for Percutaneous Endoscopic Gastrostomy
Tae Chung Hyun,Lee Ju Yup,Joo Moon Kyung,Park Chan Hyuk,Gong Eun Jeong,Shin Cheol Min,Lim Hyun,Choi Hyuk Soon,Choi Miyoung,Kim Sang Hoon,Lim Chul-Hyun,Byeon Jeong-Sik,Shim Ki-Nam,Song Geun Am,Lee Moon 거트앤리버 소화기연관학회협의회 2024 Gut and Liver Vol.18 No.1
With an aging population, the number of patients with difficulty swallowing due to medical conditions is gradually increasing. In such cases, enteral nutrition is administered through a temporary nasogastric tube. Long-term use of a nasogastric tube leads to various complications and a decreased quality of life. Percutaneous endoscopic gastrostomy (PEG) is the percutaneous placement of a tube into the stomach, aided endoscopically, which may be an alternative to a nasogastric tube when enteral nutritional is required for 4 weeks or more. This paper is the first Korean clinical guideline for PEG. It was developed jointly by the Korean College of Helicobacter and Upper Gastrointestinal Research and led by the Korean Society of Gastrointestinal Endoscopy. These guidelines aimed to provide physicians, including endoscopists, with the indications, use of prophylactic antibiotics, timing of enteric nutrition, tube placement methods, complications, replacement, and tubes removal for PEG based on the currently available clinical evidence.
신규 간호사의 관계지향(Reinforcement of Resilience and Relation) 프로그램 개발
이미영 ( Lee Miyoung ),전미경 ( Jeon Mi-kyeong ),이미경 ( Lee Mi-kyoung ),임숙빈 ( Im Sookbin ),변은경 ( Byun Eun Kyung ),정은자 ( Chung Eunja ) 병원간호사회 2020 임상간호연구 Vol.26 No.2
Purpose: The purpose of this study was to develop a program for reinforcing the resilience of new nurses and relation-oriented organizational culture. Methods: An Intervention Research (IR) model was used to develop a program. Literature review, focus group interviews with nurses and need surveys were conducted from August to December 2018. Based on the results of the investigation, the researcher developed the content of a program. The program was revised by nurse managers for the content validation. Results: According to the results of the need surveys, 58.8% of the participants thought relation-oriented culture was the most ideal, and 61.8% of the participants wanted to participate in a program for organizational culture improvement. In the focus group interview, not only new nurses but also wards and nursing organizations should be a target subject of the program. Reinforcement of resilience and relation (3R) program was developed as a one-year course, which includes a ‘mentor-mentee’ program and a ‘thanks’ program. Conclusion: It would contribute to improving the resilience of new nurses and creating a relation-oriented organizational culture by 3R program. The 3R program could play a role as expanded program from an existing pragmatic short-term training program for improving the competencies or communication skills of new nurses.