대만의 지능장애와 감각장애 특수학교 교장 전형 리더십에 대한 연구

蕭金土,高文民,卓美方,王金香 대구대학교 특수교육재활과학연구소 2007 再活科學硏究 Vol.25 No.1

최근 몇 년 회귀 주류와의 융합 교육 정책 하에 대만의 특수 교육 학교는 예전과 다른 큰 변화에 직면해 있다. 완전 융합 이념의 실시 또 심신장애학생을 주류교육으로 회귀해야 한다는 것을 제창함으로, 특수교육학교는 인원이 감소하게 됐다. 특수교육 학교는 신입생 모집이 부족한 상황에서 학교 교사들의 관점이 교장의 지도에 대해 보는 관점이 어떻게 다른가? 그에 대한 요구도 다른가? 본 연구는 두 인자 변의 수 분석이 대만 지능 장애와 감각 장애 종류의 특수 교육 학교 교장전형 리더십에 대한 연구이다. 실험 대상자는 8개 지능 장애종류 특수교육 학교와 5개 감각 장애종류 특수 교육 학교의 259명의 교사이고 그들이 특수교육학교 교장 리더에 대한 건의를 제출했다. In recent years, the domestic special education schools have faced with huge changes under the mainstream and inclusive education policies for the implementation of the full-inclusive and the mainstream education for the students with impairment. That causes the special education schools to reduce classes. Under this situation, what are the teachers?fdifferent views about the principal? What are their needs? The study was undertaken through two-way ANOVA to explore principals?ftransformational leadership between the schools for the mentally retarded and for the sensory impaired. 259 teachers were selected from 8 schools for the mentally retarded and 5 sensory impairment special education schools. Based upon the findings, the implications for practice were proposed.

The Relationship among Nursing Competence, Job Satisfaction, and Intention to Stay in Nursing Profession

Mei-Yao Ho,Hsiao-Mei Chang,Ming-Yi Hsu 한국간호과학회 2015 한국간호과학회 학술대회 Vol.2015 No.10

Function of Global Regulator CodY in Bacillus thuringiensis BMB171 by Comparative Proteomic Analysis

( Ming Xia Qi ),( Fei Mei ),( Hui Wang ),( Ming Sun ),( Ge Jiao Wang ),( Ziniu Yu ),( Yeon Ho Je ),( Ming Shun Li ) 한국미생물 · 생명공학회 2015 Journal of microbiology and biotechnology Vol.25 No.2

CodY is a highly conserved protein in low G+C gram-positive bacteria that regulates genes involved in sporulation and stationary-phase adaptation. Bacillus thuringiensis is a grampositive bacterium that forms spores and parasporal crystals during the stationary phase. To our knowledge, the regulatory mechanism of CodY in B. thuringiensis is unknown. To study the function of CodY protein in B. thuringiensis, BMB171codY- was constructed in a BMB171 strain. A shuttle vector containing the ORF of cry1Ac10 was transformed into BMB171 and BMB171codY-, named BMB171cry1Ac and BMB171codY-cry1Ac, respectively. Some morphological and physiological changes of codY mutant BMB171codY-cry1Ac were observed. A comparative proteomic analysis was conducted for both BMB171codY-cry1Ac and BMB171cry1Ac through two-dimensional gel electrophoresis and MALDI-TOF-MS/MS analysis. The results showed that the proteins regulated by CodY are involved in microbial metabolism, including branched-chain amino acid metabolism, carbohydrate metabolism, fatty acid metabolism, and energy metabolism. Furthermore, we found CodY to be involved in sporulation, biosynthesis of poly-β-hydroxybutyrate, growth, genetic competence, and translation. According to the analysis of differentially expressed proteins, and physiological characterization of the codY mutant, we performed bacterial one-hybrid and electrophoretic mobility shift assay experiments and confirmed the direct regulation of genes by CodY, specifically those involved in metabolism of branched-chain amino acids, ribosomal recycling factor FRR, and the late competence protein ComER. Our data establish the foundation for in-depth study of the regulation of CodY in B. thuringiensis, and also offer a potential biocatalyst for functions of CodY in other bacteria.

Study of the Synthesis and Properties of Ir(III) Complexes Based on Phosphine Carbonylimide Derivative as Auxiliary Ligand

Qing-Mei Guo,Guoli Huang,Xin-Ying Yin,Jian-Jian Bian,Xiao-Mei Li,Ming-Yu Teng 대한화학회 2020 Bulletin of the Korean Chemical Society Vol.41 No.12

Three iridium complexes of (dfppy)2Ir(DAPB), (dfppy)2Ir(DAPB), and (dfppy)2Ir(DAPB) were synthesized by using phosphine carbonylimide derivative as auxiliary ligand and fluoro?/trifluoromethyl substituted 2-phenylpyridine derivatives as primary ligands. Their quantum efficiency range from 19.4% to 38.5%, and show strong rigidochromic effect. The maximum emission wavelengths of solid-state fluorescence have remarkable red shifts from 39 to 55?nm compared with these in CH2Cl2.

An Ester Extract of Cochinchina Momordica Seeds Induces Differentiation of Melanoma B16 F1 Cells via MAPKs Signaling

Zhao, Lian-Mei,Han, Li-Na,Ren, Feng-Zhi,Chen, Shu-Hong,Liu, Li-Hua,Wang, Ming-Xia,Sang, Mei-Xiang,Shan, Bao-En Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.8

Cochinchina momordica seeds (CMS) have been widely used due to antitumor activity by Mongolian tribes of China. However, the details of the underlying mechanisms remain unknown. In the present study, we found that an EtOAc (ethyl ester) extract of CMS (CMSEE) induced differentiation and caused growth inhibition of melanoma B16 F1 cells. CMSEE at the concentration of $5-200{\mu}g/ml$ exhibited strongest anti-proliferative effects on B16 F1 cells among other CMS fractions (water or petroleum ether). Moreover, CMSEE induced melanoma B16 F1 cell differentiation, characterized by dendrite-like outgrowth, increasing melanogenesis production, as well as enhancing tyrosinase activity. Western blot analysis showed that sustained phosphorylation of p38 MAP accompanied by decrease in ERK1/2 and JNK dephosphorylation were involved in CMSEE-induced B16 F1 cell differentiation. Notably, 6 compounds that were isolated and identified may be responsible for inducing differentiation of CMSEE. These results indicated that CMSEE contributes to the differentiation of B16 F1 cells through modulating MAPKs activity, which may throw some light on the development of potentially therapeutic strategies for melanoma treatment.

消?者?新性?移?支付?APP使用意愿的影??究

全冬梅 ( Quan Dong Mei ),张明明 ( Zhang Ming Ming ),庆成林 ( Qing Cheng Lin ) 한국외국어대학교 중국연구소 2019 中國硏究 Vol.81 No.-

Mobile payment Apps such as Alipay, WeChat payment and Union-Pay are emerging in endlessly, and the competition in the mobile payment market is becoming increasingly severe. This paper divides the mobile payment Apps into perceived benefits and perceived sacrifices based on their characteristics. By means of questionnaire survey, 350 questionnaires were collected, among which 309 were valid. In addition, the model was tested by reliability analysis, validity analysis, structural equation model and path analysis. Finally, the data processing results show that:Consumer innovation has a positive effect on the perceived benefits of mobile payment Apps, that is, the higher the consumer innovation is, the higher the perceived usefulness, perceived ease of use and perceived entertainment are. Perceived benefits positively influence the perceived value of mobile payment Apps, and then promote the use intention of consumers. Perceived benefits and perceived value play a mediating role between consumers' innovation and their willingness to use mobile payment Apps.The above research conclusions clearly define the impact and function mechanism of consumer innovation on the intention to use mobile payment Apps. Therefore, the following suggestions are put forward to mobile payment enterprises: Position innovation groups and pay attention to the word-of-mouth effect. Optimize product functions and enhance the perceived usefulness of consumers. Simplify operation steps and promote advertising. Reduce payment risks and increase security guarantee.

Genetic variations in the bitter taste receptor gene TAS2R38 are related to cigarette smoking behavior in Han Chinese smokers

Qi Fei-Yan,Zhu Zhou-Hai,Li Meng,Guan Ying,Peng Qi-Yuan,Lu She-Ming,Liu Zhi-Hua,Wang Ming-Feng,Miao Ming-Ming,Chen Zhang-Yu,Li Xue-Mei,Bai Jie,Yao Jian-Hua 한국유전학회 2022 Genes & Genomics Vol.44 No.11

Background: Smoking behavior is influenced by multiple genes, including the bitter taste gene TAS2R38. It has been reported that the correlation between TAS2R38 and smoking behavior has ethnicity-based differences. However, the TAS2R38 status in Chinese smokers is still unclear. Objective: This study aims to investigate the possible relationship between genetic variations in TAS2R38 (A49P, V262A and I296V) and smoking behaviors in the Han Chinese population. Methods: The haplotype analyses were performed and smoking behavior questionnaire was completed by 1271 individuals. Genetic association analyses for smoking behavior were analyzed using chi-square test. Further, for investigating the molecular mechanism of TAS2R38 variants effect on smoking behavior, we conducted TAS2R38-PAV and TAS2R38-AVI expression plasmids and tested the cellular calcium assay by cigarette smoke compounds stimulus in HEK293. Results: Significant associations of genetic variants within TAS2R38 were identified with smoking behavior. We found a higher PAV/PAV frequency than AVI/AVI in moderate and high nicotine dependence (FTND ≥ 4; X2 = 4.611, 1 df, p = 0.032) and strong cigarette smoke flavor intensity preference (X2 = 4.5383, 1 df, p = 0.033) in participants. Furthermore, in the in vitro cellular calcium assay, total particle matter (TPM), N-formylnornicotine and cotinine, existing in cigarette smoke, activated TAS2R38-PAV but not TAS2R38-AVI-transfected cells. Conclusion: Our data highlights that genetic variations in TAS2R38 are related to smoking behavior, especially nicotine dependence and cigarette smoke flavor intensity preference. Our findings may encourage further consideration of the taste process to identify individuals susceptible to nicotine dependence, particularly Han Chinese smokers.

Self-Management Programs on eGFR, Depression, and Quality of Life among Patients with Chronic Kidney Disease: A Meta-Analysis

Mei-Chen Lee,Shu-Fang Vivienne Wu,Nan-Chen Hsieh,Juin-Ming Tsai 한국간호과학회 2016 Asian Nursing Research Vol.10 No.4

Purpose: Chronic kidney disease (CKD) is a condition characterized by the gradual loss of kidney function over time. Self-management programs have been widely applied to chronic disease education programs, which are designed to delay deteriorating kidney functions, preclude depression, and improve quality of life. This study aims to analyze effectiveness of self-management programs in bettering CKD patients' eGFR, mitigating depression symptoms and improving quality of life in randomized control or clinical trials. Methods: Using key terms, a search was conducted in English-language, peer-reviewed journals on CKD that were published between 2002 and 2014 on databases including CINAHL, Cochrane Library, MEDLINE. The measurable variables included CKD patients' eGFR, depression, and quality of life. Random and fixed effects meta analysis were applied with standard error and correlation based measure of effect size. Results: Eight studies met the inclusion criteria. A self-management program significantly impacted CKD patients' depression and mental quality-of-life dimensions, with an effect size of .29 [95% confidence interval (CI) (0.07, 0.53)] and .42 [95% CI ( 0.75, 0.10)]. However, the intervention of a selfmanagement program had no significant effect on patients' eGFR as well as physical quality-of-life dimensions, with effect sizes of .06 [95% CI ( 0.69, 0.81)] and .16 [95% CI ( 0.81, 0.50)]. Conclusions: Self-management programs of patients with chronic kidney disease can improve the depression and mental quality of life. Aside from providing more objective evidence-based results, this study provides a reference for clinical health care personnel who tend to patients with CKD.

Effects of enzymolysis and fermentation of Chinese herbal medicines on serum component, egg production, and hormone receptor expression in laying hens

Mei Hong Jiang,Tao Zhang,Qing Ming Wang,Jin Shan Ge,Lu Lu Sun,Meng Qi Li,Qi Yuan Miao,Yuan Zhao Zhu Asian Australasian Association of Animal Productio 2024 Animal Bioscience Vol.37 No.1

Objective: In the present study, we aimed to investigate the effects of enzymolysis fermentation of Chinese herbal medicines (CHMs) on egg production performance, egg quality, lipid metabolism, serum reproductive hormone levels, and the mRNA expression of the ovarian hormone receptor of laying hens in the late-laying stage. Methods: A total of 360 Hy-Line Brown laying hens (age, 390 days) were randomly categorized into four groups. Hens in the control (C) group were fed a basic diet devoid of CHMs, the crushed CHM (CT), fermented CHM (FC), and enzymatically fermented CHM (EFT) groups received diets containing 2% crushed CHM, 2% fermented CHM, and 2% enzymatically fermented CHM, respectively. Results: Compared with crushed CHM, the acid detergent fiber, total flavonoids, and total saponins contents of fermented CHM showed improvement (p<0.05); furthermore, the neutral and acid detergent fiber, total flavonoids, and total saponins contents of enzymatically fermented CHM improved (p<0.05). At 5 to 8 weeks, hens in the FC and EFT groups showed increased laying rates, haugh unit, albumin height, yolk color, shell thickness, and shell strength compared with those in the C group (p<0.05). Compared with the FC group, the laying rate, albumin height, and Shell thickness in the EFT group was increased (p<0.05). Compared with the C, CT, and FC groups, the EFT group showed reduced serum total cholesterol and increased serum luteinizing hormone levels and mRNA expressions of follicle stimulating hormone receptor and luteinizing hormone receptor (p<0.05). Conclusion: These results indicated that the ETF group improved the laying rate and egg quality and regulated the lipid metabolism in aged hens. The mechanism underlying this effect was likely related to cell wall degradation of CHM and increased serum levels of luteinizing hormone and mRNA expression of the ovarian hormone receptor.

Experimental study on deformation and strength property of compacted loess

Mei, Yuan,Hu, Chang-Ming,Yuan, Yi-Li,Wang, Xue-Yan,Zhao, Nan Techno-Press 2016 Geomechanics & engineering Vol.11 No.1

A series of experimental studies are conducted on the deformation and shear strength property of compacted loess. The results reveal that the relationships of both the initial moisture content (w) and the initial degree of compaction (K) of compacted loess with cohesion (w) and the angle of internal friction (${\varphi}$) are linear. The relationship between the secant modulus ($E_{soi}$) and K is also linear. The relationship between $E_{soi}$ and w can be fitted well by a second-order polynomial. Further, when the influences of w and K are ignored, the relationship between the confined compression strain (${\varepsilon}$) and vertical pressure (p) can be expressed by a formula. A correction formula for the deformation of compacted loess caused by a change in w and K is derived on the basis of the study results.