Uniaxial Compression Properties and Compression Fatigue Performance of Selective Laser Melted Ti–6Al–4V Cellular Structure

Ming‑Wei Wu,Jhewn‑Kuang Chen,Mo‑Kai Tsai,Pei Wang,Tien‑Lin Cheng,Bo‑Huan Lin,Po‑Hsing Chiang,Annadurai Dhinakar 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.1

The selective laser melted (SLM) Ti–6Al–4V cellular solid is a promising material in biomedical and other applications. The mechanical properties of the SLM Ti–6Al–4V cellular material are predominantly controlled by the design of the cellular structure. The objective of this study was to investigate the uniaxial compressive properties and compressive fatigueperformance of the SLM Ti–6Al–4V cellular solid with a new cuboctahedron unit cell reinforced by four diagonal strutsand two horizontal struts along the X and Y axes. The infuences of hot isostatic pressing (HIP) on the various mechanicalproperties were also examined. The results showed a smoother stress–strain curve and fewer stress oscillations in the HIPspecimen than in the SLM specimen. The HIP process slightly decreased the yield strength of the SLM sample from 55 to52 MPa. Under uniaxial compressive stress, the SLM and HIP specimens exhibited layer-by-layer fracture and diagonalshear fracture, respectively. Furthermore, the HIP treatment signifcantly increased the fatigue performance and improved thefatigue endurance ratio at 106cycles from 0.15 to 0.35. The HIP treatment contributed to several positive efects, includingphase transformation from brittle α′ to α + β, the elimination of strut porosity and residual stress, an increase in lath size,and a better combination of strength and ductility, thereby improving the fatigue performance. The efects of stress mode onthe fracture mechanism were also clarifed using in situ observation in combination with digital image correlation.

朱光潛的比較詩學思想及其實踐

鐘名誠 한국중국문화학회 2002 中國學論叢 Vol.14 No.-

Zhu Guangqian is a pioneer of modern Chinese comparative poetics. In the course of the exchange between oriental culture and western culture, he looked into the Chinese modern poetic movement with his international perspective. In his research of Chinese and western poems, he applied the general principles and ideas of comparative poetics, i.e. the applicable value principles; the mutually depicting principles; the principles of the sense of history; the comprehensive comparison principles and etc., to explore the art of the Chinese and western poems Zhu has made great valuable efforts in the comparative research of western and Chinese poems and had made great contributions to the healthy development of Chinese modern poems. Today whenever we encounter any difficulties in our modern Chinese poems, we will refer to Zhu's comparative poetics thoughts. We find Zhu's thoughts still very practical and instructive.

녹음 구어 제시가 중도정신지체 성인여성의 목욕 능력 개선에 미치는 효과

鄭如意,陳明聰,陳政見 대구대학교 특수교육재활과학연구소 2006 再活科學硏究 Vol.24 No.2

1. This study aimed to explore the effect of recorded auditory prompts on helping an adult with profound mental retardation to take bath independently. 「A-B-C-A-C」design, a kind of single-subject experiment was adopted. Three phases, baseline phase, intervention phase(B): auditory prompt, and intervention phase(C): recorded auditory prompt were included. A female with profound mental retardation participated in the experiment. It took over seven months to finishing the intervention. The results of the experiment indicated that auditory prompts, whether human auditory prompt or recorded prompt, could help the client to take bath more independently. The families of the client also regarded recorded auditory prompt was a feasible solution. Based on the result, there were some suggestions for the further research. 본 연구의 목적은 녹음 구어 제시를 이용해서 극 중도 지능장애 성인 여성 스스로 목욕 동작을 완성 할 수 있도록 도와주는 효과에 대한 연구입니다. 본 연구에 사용하는 연구법은 ⌜A-B-A-C-A-C⌟역 설계이다. 기선기의(A)개입一(B)인공구어제시 개입二(C)녹음 구어 제시로 나누어졌다. 실험기간은 모두 7개월 반이었다. 연구결과는 피 실험자가 스스로 목욕할 때와 비교했을 때 인공구어 제시와 녹음구어 제시는 모두 피 실험자가 목욕 동작을 완성 하는 데에 효과가 있는 것으로 나타났다. 이 외에도 녹음 구어 제시는 피 실험자 가족들도 받아들일 수 있다. 본 연구 결과에 근거해서 연구자들은 미래 응용과 연구에 대한 건의도 제출하였다.

Tenofovir Alafenamide for Chronic Hepatitis B Patients with Advanced Fibrosis and Partial Virologic Responses to Oral Nucleos(T)Ide Analogues- Interim Report

( Ming-lung Yu ),( Ming-lun Yeh ),( Chi-yi Chen ),( Pin-nan Cheng ),( Ming-jong Bair ),( Jyh-jou Chen ),( Ching-chu Lo ),( Chi-ming Tai ),( Ching-yang Tsai ),( Kuo-chih Tseng ),( Chien-hung Chen ),( C 대한간학회 2020 춘·추계 학술대회 (KASL) Vol.2020 No.1

Aims: Insufficient data regarding the treatment strategy for partial response to nucleot(s)ide analogue (NUC) raised the aim of investigating tenofovir alafenamide (TAF) switching for chronic hepatitis B (CHB) patients with advanced fibrosis and partial response to other NUCs. Methods: CHB patients with advanced fibrosis (stage 3 or 4) and under NUC (except TAF) therapy with detectable hepatitis B virus (HBV) DNA for >52 weeks are enrolled to TAF 25 mg/day for 96 weeks. The objectives are viral suppression, alanine aminotransferase (ALT) normalization and safety. Results: From Feb. 2019, 34 patients, including 21 (61.8%) with entecavir, 10 (29.4%) TDF and 3 (8.8%) lamivudine or adefovir, were enrolled (15 [44.1%] male, median 53 years). The fibroscan demonstrated a mean of 10.5 kPa (7 [20.6%] cirrhotic). Sixteen (47.1%) patients were HBV e antigen positive, seven (20.6%) had YMDD mutation. The median HBV DNA level declined from 68.5 IU/mL at enrollment to 27.0 IU/mL at 4^th week, and undetectable at 12^th, 24^th, 36^th week, respectively, after TAF switching, with undetectable HBV DNA in 14/34 (41.2%), 17/33 (51.5%), 15/25 (60.0%), and 9/15 (60.0%) patients and rate of ALT normalization (≤40 U/L) of 85.3%, 85.3%, 84.8%, 92.0%, and 80.0%, respectively, after TAF switching. (figure 1) Two patients experienced transient virological breakthrough and another one developed at the final time follow up. Serum creatinine and eGFR levels were stable after TAF switching (figure 1). Two patients early terminated including one at 12^th week due to personal reason, and another one accidently died at 20^th week due to acute heart attack. Others suffered only mild degrees of adverse events which were considered unrelated to treatment. Conclusions: The preliminary results demonstrated the TAF switching is effective and safe in viral suppression for CHB patients with advanced fibrosis and partial virologic responses to other NUCs.

Sofosbuvir/Ledipasvir in the Treatment of Chronic Hepatitis C - A Subgroup Analysis from A Nationwide Real-World HCV Registry Program (TACR) in Taiwan

( Ming-Lung Yu ),( Chi-Yi Chen ),( Kuo-Chih Tseng ),( Ching-Chu Lo ),( Pin-Nan Cheng ),( Cheng-Yuan Peng ),( Ming-Jong Bair ),( Chih-Lang Lin ),( Chi-Ming Tai ),( Chi-Chieh Yang ),( Chih-Wen Lin ),( C 대한간학회 2020 춘·추계 학술대회 (KASL) Vol.2020 No.1

Aims: TASL HCV Registry (TACR) is a nationwide registry program organized and supervised by Taiwan Association for the Study of the Liver (TASL), which aims to setup the database and biobank of patients with chronic hepatitis C (CHC) in Taiwan. The present study aimed to evaluate the treatment outcome of sofosbuvir (SOF)/ledipasvir (LDV) in Taiwanese CHC patients in TACR. Methods: By May 2020, 19 tertiary hospitals, 23 community hospitals and one primary care clinic join the TACR program. The baseline characteristics, prior liver and non-liver related medical history, DAA regimens, laboratory results, treatment course and outcome were recorded. The primary objective was sustained virological response, defined as undetectable HCV RNA 3 months after end-of-treatment (SVR12). Results: A total of 4742 SOF/LDV+ ribavirin treated CHC patients with available SVR12 data from 39 sites were enrolled in the current analysis. The mean age was 61.3 years, and female accounted for 54.8% of the population. The dominant viral genotypes were GT1b (52.6%) and GT2 (35.6%). 1354 (28.6%) patients had liver cirrhosis, including 156 (3.3%) with liver decompensation, 552 (11.6%) had preexisting hepatocellular carcinoma (HCC) before DAAs treatment and 413 (8.7%) had hepatitis B virus dual infections. The overall SVR12 rate was 98.5%, with 98.5%, 98.2%, 99.7% and 98.6% in treatment- naïve non-cirrhotics, treatment-naïve cirrhotics, treatment- experienced non-cirrhotics and treatment-experienced cirrhotics patients, respectively. While patients were stratified by HCV genotype, the SVR12 was 98.5%, 98.4% and 98.5% among those with GT1, GT2 and GT6 infection, respectively. The strongest factor independent associated with treatment failure was DAA adherence < 60% (odds ratio [OR]/95% confidence intervals [CI]: 125.4/25.7-612.4, P<0.0001), followed by active HCC (OR/CI: 6.20/2.57-14.97, P<0.0001), HIV co-infection (OR/CI: 3.01/1.14-7.92, P=0.026), and male gender (OR/ CI: 1.85/1.09-3.13, P=0.023). The eGFR decreased significantly at the end of treatment (EOT) (89.3 ml/min/1.73㎡ vs. 93.2 ml/min/1.73㎡, P< 0.001) and remained stable 3 months after EOT (89.3 ml/min/1.73㎡). However, the decreased eGFR was observed only in patients whose baseline eGFR > 90 ml/ min/1.73㎡. Instead, patients with chronic kidney diseases whose pretreatment eGFR < 60 ml/min/1.73㎡ had improved eGFR after SOF/LDV. Conclusions: SOF/LDV is highly effective in treating CHC patients in real-world setting of Taiwan. The satisfactory result could be explicitly generalized to patients with different viral genotypes and liver disease severities.

RepFinder : Finding Approximately Repeated Scene Elements for Image Editing

Ming-Ming Cheng,Fang-Lue Zhang,Niloy J. Mitra,Xiaolei Huang,Shi-Min Hu (사)한국CDE학회 2010 한국CAD/CAM학회 국제학술발표 논문집 Vol.2010 No.8

Current Status, Future Trend and General Policies of Forestry in China

Ming Cheng,Su Kyoung Chun 한국가구학회 2006 한국가구학회 학술대회논문집 Vol.- No.-

With the economy reform carried on deeply step by step, forestry industry is playing a more and more important role in the country's economy. How to use the limited resources to make the largest economical benefit is a key point for the industry development, however it is exciting that our forest resources is on sustainable development gradually and forestry output value is also increasing every year, input and export volume is enlarged fast, add to reasonable strategy, no doubt that China's forestry can achieve a prosperous future.

Optimal Design and Dynamic Control of Construction Dewatering with the Consideration of Dewatering Process

Cheng-hua Shi,Cheng-yong Cao,Ming-feng Lei,Li-min Peng,Jing Jiang 대한토목학회 2017 KSCE Journal of Civil Engineering Vol.21 No.4

Design optimization of construction dewatering has important values in protecting the surrounding environment and reducing the engineering cost. The existing dewatering design methods are mostly based on the optimization of pumping rate needed to maintain a stable water level, while the drop and rise of water level are not considered in the estimation of pumping rate and dewatering time. The dynamics process of construction dewatering is taken into account in this article. The method for calculating the total water yield and dewatering time from the initial groundwater level to the target water level is established. Then, the design optimization of well group dewatering is provided with the consideration of total water yield and dewatering time in dynamic dewatering process. Finally, the method for the calculation of total water yield and dewatering time when dewatering regions change is derived. The proposed method can realize design optimization and dynamic control of dewatering as the dewatering regions and water level changes in construction. The reliability of this method is verified in on-site engineering applications.

Development and Situation of Chinese Forest Resources

Ming Cheng,Su Kyoung Chun 한국가구학회 2006 한국가구학회 학술대회논문집 Vol.- No.-

China has a very large area, but the total and average amount of forest resources are always relative scarcity, retrospect the forest history, when the activities of human beings existed on the earth, the forest resources began to reduce gradually, it indicates that the amount of the forest resources have grate connection with the activities of human beings, especially from the foundation of New China, long term out-of- order logging and unsustainable development make the forest resources and ecological environment be destructed seriously. However, although Chinese forest resources still face a large number of complicated problems, it has already begun to recover and been into the right orbit through listing and analysis a series dates. Additionally, six key forest resources program's launching and the strategy shifting will take China enter a bright future.

Visual Servoing of a Micro Quadrotor Landing on a Ground Platform

Cheng-Ming Huang,Ming-Li Chiang,Tzu-Shun Hung 제어·로봇·시스템학회 2017 International Journal of Control, Automation, and Vol.15 No.6

This paper presents a visual servoing methodology for landing a quadrotor-type micro aerial vehicle(MAV) on a ground platform in an indoor environment. Since space in an indoor environment is usually limited, thesizes of the MAV and the landing platform employed here have to be small. Thus, visual servoing based on two pinholecameras mounted on the front and bottom of a MAV is suitable for such a scenario. A powerful computationalprocessing unit for image or control processing and a high capacity battery for charging the MAV are equipped onthe ground platform. The captured images and the flying control commands are transmitted between the groundplatform and the MAV through a wireless network. Visual feature extraction of the landing platform is proposedto detect a specific image pattern on the landing platform. Flying control strategies, with the cameras switching,are developed to search for and approach the landing platform. Alignment control during the landing procedure isdesigned using multi-level fuzzy logic control with the target position error on the image. The overall performanceof the landing algorithm is validated by several online experiments with a commercialized MAV.