A 3-Gb/s Equalizer with an Adaptive Swing Controller for TFT-LCD Interfaces

Miao-Shan Li,Yen-Chen Lin,Chai-Chi Liu,Ching-Rong Chang,Jyun-Yi Li,You-Sheng Lin,Ching-Yuan Yang 대한전자공학회 2019 Journal of semiconductor technology and science Vol.19 No.1

A 0.18-μm CMOS 3-Gb/s equalizer with an adaptive swing controller is presented for 4K2K large display panels to compensate a 24-dB channel loss. Employing the output-swing control technique, we propose the adaptive loop for the equalizer to improve adaptation accuracy without degrading the boost tuning and input swing ranges. Besides, cascading two bandpass filters (BPF) measured energy in a narrow range is much more accuracy than conventional highpass filters (HPF). The measured jitter of 3-Gb/s and 1.5-Gb/s data are 0.23-UI and 0.356-UI for 1.23-m FR4 board, respectively. The core area occupies 0.12-㎟ and the power consumption is 27-mW at 3 Gb/s from a 1.8-V supply.

An Extended Plant Circadian Clock Model for Characterising Flowering Time under Different Light Quality Conditions

Miao Lin Pay,Jesper Christensen,Fei He,Laura Roden,Hafiz Ahmed,Mathias Foo 제어로봇시스템학회 2022 제어로봇시스템학회 국제학술대회 논문집 Vol.2022 No.11

Speed breeding has recently emerged as an innovative agricultural technology solution to meet the ever-increasing global food demand. In speed breeding, typically various light qualities (e.g., colour, duration, intensity) are modified to manipulate the circadian clock of the plants, which in turn alter the plant growth and enhance the productivity such as by reducing the flowering time. In order to develop a comprehensive framework describing plant growth, a model incorporating the effect of various light qualities on plant growth needs to be established. Recently a mathematical model of the plant circadian clock for Arabidopsis thaliana has been developed to characterise the hypocotyl growth subject to multiple light quality properties. This is a first step towards developing a more comprehensive model that links light quality, plant circadian clock and plant growth. In this work, we extend the model by adding the effect of various light qualities on the flowering time. The proposed model can capture the flowering time behaviours of plant when subject to red, blue, and mixed lights and can be used to guide experiment of light properties manipulation for optimised plant growth via hypocotyl growth and flowering time.

miR-29 family inhibited the proliferation and migration of lung cancer cells by targeting SREBP-1

Lin Lin,Bao Yongxia,Tian Miao,Ren Qiu,Zhang Wei 대한독성 유전단백체 학회 2022 Molecular & cellular toxicology Vol.18 No.2

Backgrounds Lipid metabolism dysregulation is an important characteristic of tumor cells. Increased lipid metabolism provides a vital material and energy source for tumor growth, thereby promoting tumor invasion and metastasis. Objectives In the current work, we carried out a series of in vivo and in vitro studies to explore the relationship between miR-29 and lung cancer. Results The results showed that miR-29 was down-regulated in lung cancer, and overexpression of miR-29 inhibited the proliferation and migration of lung cancer cells (in vitro). Anti-lung cancer effect of miR-29 in vivo was evaluated, and results indicated that transfection of miR-29b/c markedly inhibited lung tumor growth (in vivo). We further explored the potential mechanism by which miR-29 could inhibit the cell proliferation of lung cancer. It is well known that lipid metabolism dysregulation is an important characteristic of tumor cells. Increased lipid metabolism provides a vital material and energy source for tumor growth, thereby promoting tumor invasion and metastasis, and sterol regulatory element-binding protein 1 (SREBP) is involved in liposome metabolism. Therefore, we analyzed the interaction between miR-29C and SREBP-1 in lung cancer cells. Bioinformatics analysis showed that the miR-29 has the potential binding site on SCAP and SREBP mRNA, and Luciferase reporter gene assays revealed the interaction between 3′UTR of SREBP-1 mRNA and miR-29c. Further study showed that miR-29 suppressed (SREBP-1) expression by interacting with 3′UTR of SREBP-1. Further work indicated that miR-29 transfection strongly inhibited lung cancer cell proliferation, which was rescued by the overexpression of SREBP-1. Conclusion These fi ndings demonstrate that transfection of miR-29 suppressed lung cancer proliferation via inhibiting SREBP-1 expression. The current study provides a basis for exploring the targeted agents against lung cancer.

Semantic Behavior of Indexed Co-inductive Data Type in Fibrational Setting

Miao De-cheng,Xi Jian-qing,Jiang Chang-jin,Liang Yong-lin 보안공학연구지원센터 2016 International Journal of u- and e- Service, Scienc Vol.9 No.6

Traditional methods such as category theory and coalgebra have some drawbacks to analyze semantic behavior of indexed co-inductive data type. Aiming at the problem above, this paper explored indexed co-inductive data type in programming by Fibrations theory. Our main work was that we firstly made some basic logical structures of indexed co-inductive data type over a fibration such as truth and quotient functor; using endo-functor in base categories and their equation-preserving lifting in total categories, then we analyzed semantic behavior of indexed co-inductive data type; at last we briefly introduced applications of Fibrations theory on indexed co-inductive data type by example. Compared with traditional methods, brief descriptions and flexible expansibility of Fibrations theory can analyze semantic behavior of indexed co-inductive data type accurately, and superior abstractness of Fibrations theory doesn’t rely on particular computing environments to compute semantics.

Synthesis and electrochemical performance of Li1þxV3O8 as cathode material prepared by citric acid and tartaric acid assisted solegel processes

Miao Shui,Weidong Zheng,Jie Shu,Qingchun Wang,Shan Gao,Dan Xu,Liangliang Cheng,Lin Feng,Yuanlong Ren 한국물리학회 2013 Current Applied Physics Vol.13 No.3

Lithium-ion battery cathode material Li1þxV3O8 is synthesized by a citric acid/tartaric acid assisted sol egel method and sintered at 350 C, 450 C and 550 C for 3 h for the formation of Li1þxV3O8 phase. The synthesized samples were fully characterized by FTIR, TG/DTA, XRD, SEM, EIS and chargeedischarge tests. Li1þxV3O8 material synthesized by tartaric acid assisted route and sintered at 450 C for 3 h shows best electro-chemical performance. It shows a high initial capacity of 249 mAh g1 and still reserves a discharge capacity of 260 mAh g1 after 50 cycles. Moreover, in the case of tartaric assisted products, no capacity decadence is observed in 50 cycles. XRD together with TG/DTA measurements reveal that compared with citric acid assisted products, the adoption of tartaric acid as chelating agent effectively lowers the crystallization temperature of amorphous Li1þxV3O8. Therefore, precursors obtained by tartaric acid route calcinated at 450 C for 3 h exhibit lower crystallinity and smaller grain size, which contributes to the better electrochemical performance of the cathode electrodes. From EIS measurements, the bulk resistance is reduced, which favors the intercalation and de-intercalation of lithium ions while cycling.

Efficient Mining Maximal Subspace Differential Co-expression Patterns in Matrix Datasets : a General Earthquake Analysis Approach

Miao Wang,Zhiyong Xiong,Liang Xu,Lihua Zhang,Cheng Gong,Yi Hu,Yi Lin 보안공학연구지원센터 2015 International Journal of Database Theory and Appli Vol.8 No.3

The electromagnetic anomaly observations before earthquake, have been confirmed by many cases of strong earthquakes. The analysis of earthquake magnetic anomaly is an effective approach for seismo-precursor detection. Traditional frequent mining methods for electromagnetic matrix datasets analysis often find the co-related items. However, these methods may miss the items which are differential co-related patters under different datasets. Mining these differential co-related patterns is more valuable for inferring potential knowledge. In this paper, we develop an algorithm, MSPattern, to mine maximal subspace differential co-expression patterns. MSPattern constructs a weighted undirected item-item relational graph firstly. Then all the maximal co-related patterns would be mined using item-growth method in above graph. MSPattern also utilizes several techniques for producing maximal patterns without candidate patterns maintenance. Evaluated by real electromagnetic matrix datasets and the gene expression datasets, the experimental results show our algorithm can find some potential knowledge for earthquake analysis, and MSPattern algorithm is more efficient than traditional ones. The performance of MSPattern is also evaluated by empirical p-value and gene ontology, the results show our algorithm can find statistical significant and biological differential co-expression patterns.

Rhizospheric fungi of Panax notoginseng: diversity and antagonism to host phytopathogens

Miao, Cui-Ping,Mi, Qi-Li,Qiao, Xin-Guo,Zheng, You-Kun,Chen, You-Wei,Xu, Li-Hua,Guan, Hui-Lin,Zhao, Li-Xing The Korean Society of Ginseng 2016 Journal of Ginseng Research Vol.40 No.2

Background: Rhizospheric fungi play an essential role in the plantesoil ecosystem, affecting plant growth and health. In this study, we evaluated the fungal diversity in the rhizosphere soil of 2-yr-old healthy Panax notoginseng cultivated in Wenshan, China. Methods: Culture-independent Illumina MiSeq and culture-dependent techniques, combining molecular and morphological characteristics, were used to analyze the rhizospheric fungal diversity. A diffusion test was used to challenge the phytopathogens of P. notoginseng. Results: A total of 16,130 paired-end reads of the nuclear ribosomal internal transcribed spacer 2 were generated and clustered into 860 operational taxonomic units at 97% sequence similarity. All the operational taxonomic units were assigned to five phyla and 79 genera. Zygomycota (46.2%) and Ascomycota (37.8%) were the dominant taxa; Mortierella and unclassified Mortierellales accounted for a large proportion (44.9%) at genus level. The relative abundance of Fusarium and Phoma sequenceswas high, accounting for 12.9% and 5.5%, respectively. In total,113 fungal isolates were isolated from rhizosphere soil. They were assigned to five classes, eight orders (except for an Incertae sedis), 26 genera, and 43 species based on morphological characteristics and phylogenetic analysis of the internal transcribed spacer. Fusarium was the most isolated genus with six species (24 isolates, 21.2%). The abundance of Phoma was also relatively high (8.0%). Thirteen isolates displayed antimicrobial activity against at least one test fungus. Conclusion: Our results suggest that diverse fungi including potential pathogenic ones exist in the rhizosphere soil of 2-yr-old P. notoginseng and that antagonistic isolates may be useful for biological control of pathogens.

Super-Lift DC-DC Converters: Graphical Analysis and Modelling

Miao Zhu,Fang Lin Luo 전력전자학회 2009 JOURNAL OF POWER ELECTRONICS Vol.9 No.6

Super-lift dc-dc converters are a series of advanced step-up dc-dc topologies that provide high voltage transfer gains by super-lift techniques. This paper presents a developed graphical modelling method for super-lift converters and gives a thorough analysis with a consideration of the effects caused by parasitic parameters and diodes’ forward voltage drop. The general guidelines for constructing and deriving graphical models are provided for system analysis. By applying it to examples, the proposed method shows the advantages of high convenience and feasibility. Both the circuit simulation and experimental results are given to support the theoretical analysis.

A split spectrum processing of noise-contaminated wave signals for damage identification

Miao, X.T.,Ye, Lin,Li, F.C.,Sun, X.W.,Peng, H.K.,Lu, Ye,Meng, Guang Techno-Press 2012 Smart Structures and Systems, An International Jou Vol.10 No.3

A split spectrum processing (SSP) method is proposed to accurately determine the time-of-flight (ToF) of damage-scattered waves by comparing the instantaneous amplitude variation degree (IAVD) of a wave signal captured from a damage case with that from the benchmark. The fundamental symmetrical ($S_0$) mode in aluminum plates without and with a notch is assessed. The efficiency of the proposed SSP method and Hilbert transform in determining the ToF of damage-scattered $S_0$ mode is evaluated for damage identification when the wave signals are severely contaminated by noise. Broadband noise can overwhelm damage-scattered wave signals in the time domain, and the Hilbert transform is only competent for determining the ToF of damage-scattered $S_0$ mode in a noise-free condition. However, the calibrated IAVD of the captured wave signal is minimally affected by noise, and the proposed SSP method is capable of determining the ToF of damage-scattered $S_0$ mode accurately even though the captured wave signal is severely contaminated by broadband noise, leading to the successful identification of damage (within an error on the order of the damage size) using a triangulation algorithm.

Long-term Survivals, Toxicities and the Role of Chemotherapy in Early-Stage Nasopharyngeal Carcinoma Patients Treated with Intensity-modulated Radiation Therapy: A Retrospective Study with 15-year Follow-up

Lin Wang,Jingjing Miao,Huageng Huang,Boyu Chen,Xiao Xiao,Manyi Zhu,Yingshan Liang,Weiwei Xiao,Shaomin Huang,Yinglin Peng,Xiaowu Deng,Xing Lv,Weixiong Xia,Yanqun Xiang,Xiang Guo,Fei Han,Chong Zhao 대한암학회 2022 Cancer Research and Treatment Vol.54 No.1

Purpose This study was aimed to investigate long-term survivals and toxicities of early-stage nasopharyngeal carcinoma (NPC) in endemic area, evaluating the role of chemotherapy in stage II patients. Materials and Methods Totally 187 patients with newly diagnosed NPC and restaged American Joint Committee on Cancer/ International Union Against Cancer 8th T1-2N0-1M0 were retrospectively recruited. All received intensity-modulated radiotherapy (IMRT)±chemotherapy (CT) from 2001 to 2010. Results With 15.7-year median follow-up, 10-year locoregional recurrence-free survival, distant metastasis-free survival (DMFS), disease-specific survival (DSS), and overall survival (OS) were 93.3%, 93.5%, 92.9% and 88.2%, respectively. Multivariable analyses showed cervical lymph nodes positive and pre-treatment prognostic nutritional index ≥ 52.0 could independently predict DMFS (p=0.036 and p=0.011), DSS (p=0.014 and p=0.026), and OS (p=0.002 and p < 0.001); Charlson comorbidity index < 3 points could predict DSS (p=0.011); age > 45 years (p=0.002) and pre-treatment lactate dehydrogenase ≥ 240 U/L (p < 0.001) predicted OS. No grade 4 late toxicity happened; grade 3 late toxicities included subcutaneous fibrosis (4.3%), deafness or otitis (4.8%), skin dystrophy (2.1%), and xerostomia (1.1%). No differences on survivals were shown between IMRT+CT vs. IMRT alone in stage II patients, even in T2N1M0 (p > 0.05). Unsurprising, patients in IMRT+CT had more acute gastrointestinal reaction, myelosuppression, mucositis, late ear toxicity, and cranial nerve injury (all p < 0.05) than IMRT alone group. Conclusion Superior tumor control and satisfying long-term outcomes could be achieved with IMRT in early-stage NPC with mild late toxicities. As CT would bring more toxicities, it should be carefully performed to stage II patients.