The Properties of Planck Galactic Cold Clumps in the L1495 Dark Cloud

Tang, Mengyao,Liu, Tie,Qin, Sheng-Li,Kim, Kee-Tae,Wu, Yuefang,Tatematsu, Ken’ichi,Yuan, Jinghua,Wang, Ke,Parsons, Harriet,Koch, Patrick M.,Sanhueza, Patricio,Ward-Thompson, D.,Tó,th, L. Viktor,S American Astronomical Society 2018 The Astrophysical journal Vol.856 No.2

Rotor ground-fault diagnosis methods for synchronous condensers based on amplitude and phase-angle of voltage

Jiang, Mengyao,Ma, Hongzhong,Zhao, Shuai,Tang, Xiaozheng,Liu, Yidan The Korean Institute of Power Electronics 2020 JOURNAL OF POWER ELECTRONICS Vol.20 No.5

A single ground fault of the rotor windings in a synchronous condenser can cause serious damage if the fault is not eliminated in time. This paper proposes a new rotor ground-fault diagnosis method for synchronous condensers based on the amplitude of the 150 Hz component of the voltage across a grounding resistance (GR) placed in the neutral of an excitation transformer. It can be seen that the amplitude of the 150 Hz component of the voltage across the GR increases with a decrease of the ground-fault resistance (GFR). This method is an improvement of existing algorithms for rotor ground-fault detection that requires less analyzing and can achieve online detection of the severity of a rotor ground fault at any point of the excitation winding. In addition, the influence of different excitation voltages on the algorithm based on phase-angle is analyzed considering actual working characteristics. Moreover, a model is built in the MATLAB/Simulink platform using the real parameters of a TTS-300-2 synchronous condenser to verify the effectiveness of the proposed method. Finally, a dual diagnostic criterion is given according to the results of simulations. The research conclusions can have a great significance on the healthy running of synchronous condensers and they can help to drastically reduce both cost and repair time.

Differential Hrd1 Expression and B-Cell Accumulation in Eosinophilic and Non-eosinophilic Chronic Rhinosinusitis With Nasal Polyps

Kun Chen,Miaomiao Han,Mengyao Tang,Yadong Xie,Yuting Lai,Xianting Hu,Jia Zhang,Jun Yang,Huabin Li 대한천식알레르기학회 2018 Allergy, Asthma & Immunology Research Vol.10 No.6

Purpose: Hrd1 has recently emerged as a critical regulator of B-cells in autoimmune diseases. However, its role in the pathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNP) remains largely unexplored. This study aimed to examine Hrd1 expression and B-cell accumulation and their possible roles in CRSwNP. Methods: Quantitative real-time polymerase chain reaction, immunohistochemistry, enzyme-linked immunosorbent assay and Western blotting were used to assess gene and protein expression in nasal tissue extracts. Cells isolated from nasal tissues and peripheral blood mononuclear cells were characterized by flow cytometry. Local antibody production was measured in tissue extracts with a Bio-Plex assay. Additionally, changes in Hrd1 expression in response to specific inflammatory stimuli were measured in cultured dispersed polyp cells. Results: Nasal polyps (NPs) from patients with eosinophilic CRSwNP (ECRS) had increased levels of Hrd1, B-cells and plasma cells compared with NPs from patients with non-eosinophilic CRSwNP (non-ECRS) or other control subjects (P < 0.05). The average Hrd1 levels in B-cells in NPs from ECRS patients were significantly higher than those from non-ECRS patients and control subjects (P < 0.05). NPs also contained significantly increased levels of several antibody isotypes compared with normal controls (P < 0.05). Interestingly, Hrd1 expression in cultured polyp cells from ECRS patients, but not non-ECRS patients, was significantly increased by interleukin-1β, lipopolysaccharide and Poly(I:C) stimulation, and inhibited by dexamethasone treatment (P < 0.05). Conclusions: Differential Hrd1 expression and B-cell accumulation between the ECRS and non-ECRS subsets suggests that they can exhibit distinct pathogenic mechanisms and play important roles in NP.

The genome of Bacillus aryabhattai T61 reveals its adaptation to Tibetan Plateau environment

Ping Wan,ZhiWei Yang,Yan Yan,Lei Zhang,MengYao Yu,Jian Wang,He Tang 한국유전학회 2016 Genes & Genomics Vol.38 No.3

Tibetan Plateau is called ‘the Roof of the World’. Organisms survive there have to adapt to the high altitude environment. By shotgun method, we sequenced the genome of Bacillus aryabhattai T61, which inhabits in the soil at the altitude of 4123 m in Shigatse, Tibetan. Further, we explored the genomic basis for its adaptations to the plateau environment. The results showed that B. aryabhattai T61 has evolved an array of ROS defense systems and sporulation system for adaptations to the stresses caused by the plateau strong ultraviolet radiation, extreme oxygen limitation and low temperature. Specifically, B. aryabhattai T61 encodes the ResE–ResD twocomponent to sense the oxygen limitation and regulates COX15 for aerobic and anaerobic respiration. The twocomponent system DesK–DesR, which regulates the gene Des initiating the biosynthesis of unsaturated fatty acids, along with 33 temperature-shock proteins contribute to low temperature adaptation. With the comparative analysis, we deduced the novel gene cbiY may be involved in cobalamin biosynthesis. We also found that B. aryabhattai T61 may have novel regulatory mechanisms for sporulation initiation. B. aryabhattai T61 is the first Tibetan strain with high quality genome sequenced. The genome provides a paradigm for understanding the adaptations to the plateau environment in Bacteria kingdom.

Backbone Coplanarity Tuning of 1,4-Di(3-alkoxy-2-thienyl)-2,5-difluorophenylene-Based Wide Bandgap Polymers for Efficient Organic Solar Cells Processed from Nonhalogenated Solvent

Liao, Qiaogan,Yang, Kun,Chen, Jianhua,Koh, Chang Woo,Tang, Yumin,Su, Mengyao,Wang, Yang,Yang, Yinhua,Feng, Xiyuan,He, Zhubing,Woo, Han Young,Guo, Xugang American Chemical Society 2019 ACS APPLIED MATERIALS & INTERFACES Vol.11 No.34

<P>Halogenated solvents are prevailingly used in the fabrication of nonfullerene organic solar cells (NF-OSCs) at the current stage, imposing significant restraints on their practical applications. By copolymerizing phthalimide or thieno[3,4-<I>c</I>]pyrrole-4,6-dione (TPD) with 1,4-di(3-alkoxy-2-thienyl)-2,5-difluorophenylene (DOTFP), which features intramolecular noncovalent interactions, the backbone planarity of the resulting DOTFP-based polymers can be effectively tuned, yielding distinct solubilities, aggregation characters, and chain packing properties. Polymer DOTFP-PhI with a more twisted backbone showed a lower degree of aggregation in solution but an increased film crystallinity than polymer DOTFP-TPD. An organic thin-film transistor and NF-OSC based on DOTFP-PhI, processed with a nonhalogenated solvent, exhibited a high hole mobility up to 1.20 cm<SUP>2</SUP> V<SUP>-1</SUP> s<SUP>-1</SUP> and a promising power conversion efficiency up to 10.65%, respectively. The results demonstrate that DOTFP is a promising building block for constructing wide bandgap polymers and backbone coplanarity tuning is an effective strategy to develop high-performance organic semiconductors processable with a nonhalogenated solvent.</P> [FIG OMISSION]</BR>

Genome‑wide identification of GMP genes in Rosaceae and functional characterization of FaGMP4 in strawberry (Fragaria × ananassa)

Yuanxiu Lin,Jiahao Zhang,Lintai Wu,Yunting Zhang,Qing Chen,Mengyao Li,Yong Zhang,Ya Luo,Yan Wang,Xiaorong Wang,Haoru Tang 한국유전학회 2021 Genes & Genomics Vol.43 No.6

Background GDP-D-mannose pyrophosphorylase (GMP) is one of the key enzymes determining ascorbic acid (AsA) biosynthesis. However, little information about GMP genes is currently available for the Rosaceae species, especially in the AsA-riched cultivated octoploid strawberry (Fragaria × ananassa). Objective To identify the all the GMP genes in Rosaceae, as well as the predominant homologues and the role of GMP genes in strawberry AsA accumulation. Methods In the present study, we performed genome-wide identifcation and comprehensive analysis of the duplicated GMP genes in strawberry and other Rosaceae species by bioinformatics methods, the expression of the GMP genes from cultivated strawberry (Fragaria × ananassa, FaGMP) was specifcally analyzed by qPCR. Finally, the FaGMP4 was transiently overexpressed in strawberry to estimate the role of GMP in regulating AsA accumulation in strawberry. Results As results, a total of 28 GMP genes were identifed in the fve Rosaceae species. The origins of duplication events analysis suggested that most GMP duplications in Rosaceae species were generated from whole genome duplication (WGD). The Ka/Ks ratio suggested that FaGMP genes underwent a stabilization selection. qPCR based expression analysis showed diferent patterns of FaGMP paralogs during fruit ripening, while FaGMP4 expressed higher in the variety containing higher AsA. Overexpression of FaGMP4 in strawberry signifcantly enhanced AsA accumulation. Furthermore, the expression of FaGMP4 under the treatment of blue and red light was largely increased in leaves while signifcantly inhibited in fruit. These results revealed the vital role of FaGMP4 in regulating AsA in strawberry.