http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Md Faruk Ahmed (검색결과 5 건)
- 무료
- 기관 내 무료
- 유료
-
Potential Therapeutic and Preventive Effect of Drinking Hydrogen-rich Water on Acute Fatigue
Md Faruk Ahmed,Jesmin Ara,AilynFadriquela,RahimaBegum,JohnyBajgai,KyuJaeLee 한국물학회 2017 한국물학회지 Vol.6 No.1
Acute fatigue is a condition defined as a sudden onset of physical and mental exhaustion particularly after a short but strenuous period of physical exercise due to effect of waste product of muscle contraction within muscle fiber and accumulation of metabolites within the muscle fiber. Until recently, it’s believed that lactic acid build-up and reactive oxygen species (ROS) resulting oxidative stress are the most common causes of muscle fatigue. With prevalence of this condition and due to the lack of effective therapeutics, fatigue-related disorders turn to alternative medicine and other non-traditional practices. Previous studies on molecular hydrogen have reported that hydrogen exerts antioxidant, anti-inflammatory and metabolic modulation properties that are beneficial to the cell. Herein we hypothesized that hydrogen-rich water (HW) might ameliorate various impairment of acute fatigue through ROS scavenging activity and elevation of metabolic profile which were related to fatigue such as blood lactate and increasing storage of muscle glycogen, thereby improving physical endurance.
-
-
-
Hair Growth Promoting Effects of Mineral-rich Spring Water in SKH-1 Hairless Mice
Rahima Begum,Jesmin Ara,Md Faruk Ahmed,Johny Bajgai,Ailyn Fadriquela,Kyu Jae Lee 한국물학회 2017 한국물학회지 Vol.6 No.1
Mineral rich spring water has been used in spa and bathing purpose that often belong to traditional medicinal therapies. It also considered as a classical alternative medicine to cure the immunological disease. Recently, mineral rich containing medicine and cosmetics has been widely applied in hair loss purpose but not tried by mineral water. Therefore, the purpose of the present study is to observe the hair growth promoting effects of mineral rich spring water in SKH-1 hairless mice. We designed this study to evaluate the mineral water has hair growth promoting effect. The experimental SKH-1 hairless mice were divided into a normal control group (NC: No treatment), a positive control group (M: 3% Minoxidil), and different concentrations of mineral water group as a treatment group (MW: 2.5%, 5%, and 10%). All the test samples were topically sprayed on the three distinct parts of the leg, dorsal and a shoulder portion (about 1 cm2 areas) of the mice skin (100 L per application), twice a day, for μ 21 days. The number of hair and length was measured by taking a photograph of using the scale bar tools of the DinoCapture 2.0 digital microscope windows software. The thickness of the hair was measured by using scanning electron microscope. After 21 days of the experiment, mice treated with 2.5% mineral water showed the preferable effect on the number of hair, length, and thickness compared to the PC group and other concentration groups. However, the positive control minoxidil has no mineral containing ingredient but it has strong activity in hair growth. In our study, we found minoxidil had shown less active in hair growth effects in SKH-1 hairless mice. These results suggest that the using of optimum concentration of mineral rich spring water might have a remarked hair growth promoting effect, as observed morphologically. Collectively, according to our studies, we hypothesized that the topical application of mineral rich spring water might represent a novel strategy for the management and therapy for hair falling purpose. However, furthermore, studies could be more assured this hair growth promoting effects.
-
Johny Bajgai,Ailyn Fadriquela,Jesmin Ara,Rahima Begum,Md Faruk Ahmed,Cheol-Su Kim,Soo-Ki Kim,Kwang-Yong Shim,Kyu-Jae Lee 한국물학회 2017 한국물학회지 Vol.6 No.1
Atopic dermatitis (AD) is a chronic relapsing allergic inflammatory skin disease that currently affects millions of children and adults worldwide. Drugs used to treat these inflammatory diseases include anti-histamines, corticosteroids and calcineurin inhibitors but these drugs have their limitations such as adverse effects with their long-term usage. Thus, researcher’s interest in several alternative and complementary therapies are continually growing and balneotherapy is one of these approaches. Therefore, we investigate the bathing effect of high concentration mineral spring water (HMW) on redox balance and immune modulation in 2,4-dinitrochlorobenzene (DNCB)-induced atopic dermatitis like inflammation in hairless mice. We induced AD-like inflammation by application of DNCB on the dorsal skin of female skh-1 hairless mice. The mice were treated with 100% pure HMW (PHMW) and 10% diluted HMW (DHMW) through bathing once a day for 4 weeks. Tacrolimus ointment (0.1%) was used as positive control (PC) and only DNCB treatment as negative control (NeC) group. The severity of skin lesion inflammation was assessed through clinical scoring and observing scratching behavior. Levels of immunoglobulin E (IgE) and inflammatory cytokines in serum were detected by ELISA and multiplex bead array system, and the levels of oxidative stress-related biomarkers and antioxidant enzyme were also measured. We found that HMW significantly decreased the scratching behavior in PHMW and DHMW groups at the 2nd week and in PHMW group at 4th week compared to NeC group. Likewise, serum IgE level was significantly decreased in DHMW group as compared to NeC group. In line, the level of inflammatory cytokines in serum such as interleukin (IL)-1 , IL-13 and tumor necrosis factor- β α were significantly inhibited in PHMW and DHMW groups compared to NeC group. In parallel, total reactive oxygen species (ROS) of serum level was significantly decreased in PHMW treatment groups compared to NeC group. Consistently, serum malondialdehyde (MDA) level in PHMW group was lower than in NeC group. By contrast, glutathione peroxidase (GPx) activity was significantly enhanced in PHMW than NeC. Collectively, our study indicates a balneotherapeutic effect of HMW on DNCB-induced AD like inflammation in hairless mice via immunomodulation and redox balance.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
