Enamel Matrix Derivative in Periodontal Regeneration

( Kathleen McCombs ) 대한치주과학회 2002 대한치주과학회 학술대회자료집 Vol.2002 No.1

Effectiveness of Hepatitis C Virus (HCV) Screening Laws in United States [US]: Evidence from Paid Claims Data from 2010 to 2016

( Darshan Mehta ),( Jeffrey Mccombs ),( Yuri Sanchez Gonzalez ),( Steven Marx ),( Sammy Saab ),( Yongkyun Won ) 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1

Aims: The World Health Organization [WHO] has set a goal of having 90% of the world’s population screened for chronic hepatitis C (HCV) infection by 2030. Starting from 2014 in the United States (US) 5 states (NY, CA, CT, MA, CO) implemented new HCV screening policies. This study assesses the effectiveness of these screening laws and projects states’ progress toward the WHO target. Methods: Claims data for 2010-2016 from Optum Clinformatics ® Data Mart, a de-identified claims database from the US were analyzed. HCV screening was identified by paid claims for CPT codes 86803, 86804, or G0742. Logistic regression models of the likelihood of a patient being screened were estimated, controlling for patient demographic and clinical characteristics. Three time periods [2010; 2011-13 and 2014-16] were used to measure the effect on screening of the availability of the newer curative agents. Variables identifying states with screening policies were entered as interaction terms with the post-2014 time period to test if new screening policies enhanced screening rates, independent of the availability effect of the newer agents. Further, the proportion of the population screened in each state was extrapolated to 2050 using each state’s 2014-16 screening rates applied to an assumed baseline diagnosis rate of 50%. Results: Relative to the annual screening rate in 2010, annual screening rates were increased by 19.9% post 2014. In the states that passed screening laws, the annual post 2014 screening rates were increased by an additional 6.4%. Among the states that passed screening laws, MA and CT increased annual screening rates but policies in NY, CA and CO had no significant effect. Other factors that increased the likelihood of a patient being screened were female gender, Medicare enrollment and presence of comorbidities like chronic kidney disease, mixed cryoglobulinemia, fatigue and coinfection with HIV and/ or HBV. Projections of screening rates suggest that NY and 4 other states without screening laws were on track to reach the WHO target by 2030 with 8 additional states attaining WHO target by 2040. 29 states would not attain this target by 2050. Conclusions: The availability of curative therapies has increased the likelihood of screening for HCV. While current efforts to increase annual HCV screening have had positive impact, over 90% of states in the US are still not on track to reach WHO target by 2030.

Investigation of the Thermal Characteristics of a Gain-guided, Index-anti-guided Fiber

김현수,Vikas Sudesh,Timothy S. McComb,Martin C. Richardson 한국물리학회 2010 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.56 No.1

We investigate the thermal characteristics of a gain guided, index anti-guided (GG+IAG) fiber. We find the minimum of the heat transfer coefficient of the coolant to reduce the temperature of the core to below the transformation point of the GG+IAG fiber material.

의제설정 이론의 재고찰

반현(Hyun Ban),Maxwell E. McCombs 한국언론학회 2007 커뮤니케이션 이론 Vol.3 No.2

본 논문은 매스 커뮤니케이션 영역에서 가장 활발하게 연구되어온 이론 가운데 하나인 의제설정 이론을 5단계 진화 모델이라는 커다란 틀 속에서 개념적으로 재정립해보고자 시도한 논문이다. 즉, 초기 미디어 의제의 공중 의제로의 전이에 관한 연구에서, 의제설정 효과의 외적 조건들에 대한 논의, 소위 ‘2차 의제설정’이라 불리는 이슈나 공적 인물의 특정 속성에 대한 전이 영역, 미디어 의제에 영향을 미치는 요인들에 대한 연구, 그리고 최근 활발하게 이루어지고 있는 분야인 의제설정 과정 이후의 다양한 효과들에 이르는 과정 등이다. 각 단계별 논의들이 기존 연구 문헌들을 통해 구체적으로 서술되었다. 본 논문에서 논의된 이론적 개념들과 접근 방식은 앞으로 학문적 논쟁과 도전의 여지를 남겨줄 수 있다. 다시 말해 이론적 진화의 완성이라기보다는 앞으로 후속 연구자들의 학문적 논쟁과 도전의 여지를 남겨줄 수 있다. 이를 위해, 추후학자들은 본 논문에서 제시된 개념들을 다양한 영역과 환경에서 다양하게 검증할 필요가 있다. 그럼에도 불구하고 본 논문은 추후 의제설정 연구와 관련된 다양한 커뮤니케이션 현상을 연구하고자 하는 학자들에게 이론적 방향을 제시하고 개념정립을 하는데 기초적 역할을 할 수 있을 것이다. This study attempts to reconceptualize agenda-setting theory, which, one of the most dynamic research fields in mass communication, has evolved into a broad perspective on news and public opinion from its initial focus on the influence that the news media have on public opinion about the issues of the days. Hundreds of studies have been done under a wide variety of circumstances, and now the theory has been expanded explanatory power by linking up with other communication theories, such as framing or priming. The evolution of agenda-setting theory has explicated five distinct theoretical areas and has expanded to include propositions about the contingent conditions for the effects, the impact of specific elements in the media’s messages, the influences that shape the media agenda, and a variety of consequences of the agenda-setting process. Each phase was discussed in detail with a variety of related literature. The concepts introduced in this paper are not the completion of theoretical evolution of agenda-setting theory. Rather, it leaves us more challenge and disputation from future scholars. Thus, the five-phase model needs to be more elaborated in terms of theoretical and methodological aspects. The theory of agenda-setting is a complex intellectual map still in the process of evolving.

Patterns of Firm Entry and Exit in Texas Home Care Industry

Dakshina G. De Silva,정호진,Robert McComb,Anita R. Schiller 한국산업경제학회 2021 한국산업경제학회 정기학술발표대회 논문집 Vol.2021 No.8

퇴원 또는 지리적 변동의 결정 요인에 대한 가정건강관리 서비스의 영향에 관심을 가졌던 기존 연구와 달리, 본 연구에서는 가정건강관리 서비스 공급자의 진입 및 퇴출 유형을 조사하였다. 특히 미국 텍사스 주의 상세한 데이터를 사용하여 가정방문간호 서비스 제공자의 진입, 성장 및 퇴출 유형의 결정 요인을 분석하였다. 실증분석을 통해 시장의 진입하는 방문간호서비스 공급자는 보완적인 의료 서비스를 제공하는 다른 보건시설들로 인해 국지화경제 효과를 누릴 수 있음을 발견하였다.

The Spillover Effects of Regional Trade Agreements on Trade

( Dakshina G. De Silva ),( Soon-cheul Lee ),( Robert P. Mccomb ),( Maurizio Zanardi ) 대외경제정책연구원 2018 Working Papers Vol.18 No.8

Agricultural pesticide use and risk of glioma in Nebraska, United States.

Lee, W J,Colt, J S,Heineman, E F,McComb, R,Weisenburger, D D,Lijinsky, W,Ward, M H BMJ Pub. Group 2005 Occupational and environmental medicine Vol.62 No.11

<P>BACKGROUND: To evaluate the risk of the adult glioma associated with farming and agricultural pesticide use, the authors conducted a population based case control study in eastern Nebraska. METHODS: Telephone interviews were conducted with men and women diagnosed with gliomas (n = 251) between 1988 and 1993 and controls (n = 498) randomly selected from the same geographical area. Unconditional logistic regression was used to calculate adjusted odds ratios (ORs) for farming and for use of individual and chemical classes of insecticides and herbicides, including pesticides classified as nitrosatable (able to form N-nitroso compounds upon reaction with nitrite). Non-farmers were used as the reference category for all analyses. RESULTS: Among men, ever living or working on a farm and duration of farming were associated with significantly increased risks of glioma (> or =55 years on a farm OR = 3.9, 95% CI 1.8 to 8.6); however, positive findings were limited to proxy respondents. Among women, there were no positive associations with farming activities among self or proxy respondents. Specific pesticide families and individual pesticides were associated with significantly increased risks among male farmers; however, most of the positive associations were limited to proxy respondents. For two herbicides and three insecticides, use was positively associated with risk among both self and proxy respondents. Based on a small number of exposed cases, ORs were significantly increased for the herbicides metribuzin (OR = 3.4, 95% CI 1.2 to 9.7) and paraquat (OR = 11.1, 95% CI 1.2 to 101), and for the insecticides bufencarb (OR = 18.9, 95% CI 1.9 to 187), chlorpyrifos (OR = 22.6, 95% CI 2.7 to 191), and coumaphos (OR = 5.9, 95% CI 1.1 to 32). CONCLUSION: The authors found significant associations between some specific agricultural pesticide exposures and the risk of glioma among male farmers but not among female farmers in Nebraska; however, most of the positive associations were limited to proxy respondents. These findings warrant further evaluation in prospective cohort studies where issues of recall bias are not a concern.</P>

환경 문제의 2차 의제설정효과

이건호(Gunho Lee),유찬윤(Chan Yun Yoo),맥스웰 맥콤스(Maxwell E. McCombs) 한국언론학회 2007 한국언론학보 Vol.51 No.2

This study explores the second level agenda setting effects of global warming issue and their relation with the issue's salience transfer. Dividing the issue into pro-environment and con-environment (or pro-economy) attributes and delivering them through pseudo-online newspapers, the study reveals that the media boost the audiences' perceived affective attribute salience better than substantive attribute salience. It is additionally supported that the affective attribute' salience transfer more likely affects the issue salience transfer than the substantive attribute does. The study results are quite different from previous researches dealing with political issues, because they posited that not the affective but the substantive attributes had closer relation with the issue examined. Consequently, they focused on examining the substantive attributes' role in public opinion formation. The current research, however, seems to herald that the affective dimension of attributes in the agenda setting study should not be missed but studied further in order to achieve the synthetic understanding of the media effects. As the first level agenda setting effects had broadened its theoretical boundaries by scrutinizing various issues, the second level agenda setting realm can be furthered by exploring diversified attributes of issues.

의제설정이론의 정향욕구 개념에 대한 탐구적 제언

이건호(Gunho Lee),유찬윤(Chan Yun Yoo),맥스웰 맥콤스(Maxwell E. McCombs) 한국언론학회 2007 한국언론학보 Vol.51 No.6

Revisiting the core psychological concept of need for orientation, this experiment examined the relationship between the magnitude of agenda-setting effects resulting from exposure to an online newspaper and three aspects of need for orientation: (1) personal involvement, newly re-conceptualized for a traditional need for orientation component of relevance (2) knowledge as an alternative to another traditional component of uncertainty, and (3) effort, an aspect deleted in the original need for orientation research during the 1970s. The results of the experiment demonstrate that all three are significantly related to agenda-setting effects, with personal involvement having the greatest weight followed by effort. Knowledge is only weakly and negatively related to the magnitude of the agenda-setting effects. Methodologically, this study introduces continuous measures for all three components, which allows the use of more sophisticated statistical procedures.

Rapid Ultrasensitive Single Particle Surface-Enhanced Raman Spectroscopy Using Metallic Nanopores

Cecchini, Michael P.,Wiener, Aeneas,Turek, Vladimir A.,Chon, Hyangh,Lee, Sangyeop,Ivanov, Aleksandar P.,McComb, David W.,Choo, Jaebum,Albrecht, Tim,Maier, Stefan A.,Edel, Joshua B. American Chemical Society 2013 NANO LETTERS Vol.13 No.10

<P>Nanopore sensors embedded within thin dielectric membranes have been gaining significant interest due to their single molecule sensitivity and compatibility of detecting a large range of analytes, from DNA and proteins, to small molecules and particles. Building on this concept we utilize a metallic Au solid-state membrane to translocate and rapidly detect single Au nanoparticles (NPs) functionalized with 589 dye molecules using surface-enhanced resonance Raman spectroscopy (SERRS). We show that, due to the plasmonic coupling between the Au metallic nanopore surface and the NP, signal intensities are enhanced when probing analyte molecules bound to the NP surface. Although not single molecule, this nanopore sensing scheme benefits from the ability of SERRS to provide rich vibrational information on the analyte, improving on current nanopore-based electrical and optical detection techniques. We show that the full vibrational spectrum of the analyte can be detected with ultrahigh spectral sensitivity and a rapid temporal resolution of 880 μs.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/nalefd/2013/nalefd.2013.13.issue-10/nl402108g/production/images/medium/nl-2013-02108g_0007.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/nl402108g'>ACS Electronic Supporting Info</A></P>