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      • Free Paper Session : Upper Gastrointestinal Tract 1 ; Symptomatic Improvement Of Dyspepsia After Helicobacter Pylori (H. Pylori) Eradication

        ( Khaira Utia ),( Ari Fahrial Syam ),( Marcellus Simadibrata ),( Siti Setiati ),( Chudahman Manan ) 대한소화기학회 2007 SIDDS Vol.9 No.-

        Background/Aims: In most studies eradication of H. pylori has resolved the symptoms of dyspepsia in patient with or without peptic ulcer. But the symptomatic improvement of dyspepsia after eradication treatment remains unclear. The aim of this study was to find symptom characteristics of dyspepsia after eradication treatment of H. pylori and to see the association between symptom of dyspepsia and H. pylori findings. Methods: This was the cross sectional study in H. pylori patients with history of dyspepsia that had been administered eradication treatment of H. pylori for 1 week in 5 years period (2002-2007). Patients were invited to be interviewed about current symptoms of dyspepsia and then underwent urea breath test (UBT) examination to identify H. pylori. Global overall symptom of dyspepsia scale was used to assess the symptoms of dyspepsia. Results: There were 22 patients (13 male and 9 female) fulfilled the eligibility criteria for this study, 36.4% patients with eradication treatment history less than 1 year, and 63.6% patients more than 1 year. The symptoms of dyspepsia, the symptoms of dyspepsia were evaluated and as much as 77.3% (17/22) of patients, the symptoms of dyspepsia were subsided, and 22.7% (5/22) of patients with persistent symptoms after eradication. After eradication treatment, 72.7% (16/22) of patients appeared with negative Helicobacter pylori finding, and 27.3% (6/22) of patients remains positive. In negative group, 75% (12/16) of patients had relieved symptoms, and 25% (4/16) of patients with persistent symptom, and in positive group, as much as 83.8% (5/6) of patients the symptoms were relieved, and 16.7% (1/6) of patient remains persistent. We didn`t find any significant association between symptoms of dyspepsia and Helicobacter pylori status (p-0.581). Conclusions: In majority of patients, symptoms of dyspepsia after eradication treatment were resolved, but no significant association between symptoms of dyspepsia and Helicobacter pylori status.

      • Biliary Disorders/Pancreatic Disorders : Common Bile Duct Stone Is The Most Cause Of Obstructive Jaundice Patient: Evaluation From Endoscopic Retrograde Cholangiopancreatography

        ( Yudianti Pangestu ),( Ari Fahrial Syam ),( Ahmad Fauzi ),( Murdani Abdullah ),( Dadang Makmun ),( Marcellus Simadibrata ),( Chudahman Manan ),( Aziz Rani ),( H Daldiyono ) 대한소화기학회 2007 SIDDS Vol.9 No.-

        Background/Aims: Obstructive jaundice may be caused by extrahepatic cholestatic (CBD stones, pancreas and ampula cancer, CBD stricture, cholangiocarcinoma) and intra hepatic cholestatic. The aim of this study was to know what was the cause of obstructive jaundice based on ERCP evaluation. Methods: We did the retrospective study based on data of ERCP in Cipto Mangunkusumo Hospital in October 2004 until Mei 2007 Results: We evaluated 95 patients which has be done ERCP examination. We got complete data in 76 patients. Male was more frequent than female (61.8% vs 38.2%), with age range was 20-80 years old (age mean was 48.47 years old). We found CBD stones in 33 (43.4%) patients, papilla vateri tumour in 10 (13.2%) patients, head of pancreatic cancer in 8 (10.5%) patients, CBD stricture in 3 (3.9%) patients, cholangiocarcinoma in 1 (1.3%) patient, Klatskin tumour in 1 (1.3%) patient and unknown etiology obstructive in 4 (5.3%) patients. Obstructive jaundice was the most indication in ERCP examination, in 47 (61.8%) patients, followed by cholelithiasis in 22 (28.9%) patients. Sphincterotomy and stones extraction has be done in 17 (22.4%) patients, ductal cleansing in 3 (3.9%) patients, CBD stenting was performed in 17 (22.4%) pasien. We sent to surgery in 13 (17.1%) patients. ERCP failed was reported in 15 (19.7%) patients, most in the of pancreatic cancer patients. Conclusions: We found CBD stones was the most cause of obstructive jaundice, based on ERCP evaluation. ERCP has done successfully in 80.3% patients and therapeutics has done in 48.7% patients.

      • KCI등재

        Role of interventional endoscopic ultrasound in a developing country

        Hasan Maulahela,Nagita Gianty Annisa,Achmad Fauzi,Kaka Renaldi,Murdani Abdullah,Marcellus Simadibrata,Dadang Makmun,Ari Fahrial Syam 대한소화기내시경학회 2023 Clinical Endoscopy Vol.56 No.1

        Background/Aims: Endoscopic ultrasound (EUS) has become an essential diagnostic and therapeutic tool. EUS was introduced in2013 in Indonesia and is considered relatively new. This study aimed to describe the current role of interventional EUS at our hospitalas a part of the Indonesian tertiary health center experience. Methods: This retrospective study included all patients who underwent interventional EUS (n=94) at our center between January 2015and December 2020. Patient characteristics, technical success, clinical success, and adverse events associated with each type of interventionalEUS procedure were evaluated. Results: Altogether, 94 interventional EUS procedures were performed at our center between 2015 and 2020 including 75 cases ofEUS-guided biliary drainage (EUS-BD), 14 cases of EUS-guided pancreatic fluid drainage, and 5 cases of EUS-guided celiac plexusneurolysis. The technical and clinical success rates of EUS-BD were 98.6% and 52%, respectively. The technical success rate was 100%for both EUS-guided pancreatic fluid drainage and EUS-guided celiac plexus neurolysis. The adverse event rates were 10.6% and 7.1%for EUS-BD and EUS-guided pancreatic fluid drainage, respectively. Conclusions: EUS is an effective and safe tool for the treatment of gastrointestinal and biliary diseases. It has a low rate of adverseevents, even in developing countries.

      • KCI등재

        The association between new generation oral contraceptive pill and the development of inflammatory bowel diseases

        Santosh Sanagapalli,Yanna Ko,Viraj Kariyawasam,Siew C Ng,Whitney Tang,Hithanadura Janaka de Silva,Minhu Chen,Kaichun Wu,Satimai Aniwan,Ka Kei Ng,David Ong,Qin Ouyang,Ida Hilmi,Marcellus Simadibrata,Pi 대한장연구학회 2018 Intestinal Research Vol.16 No.3

        Background/Aims: To examine the association between use of oral contraceptive pills (OCPs) and the risk of developing inflammatory bowel diseases (IBD), in a modern cohort. Methods: A prospective nested case-control study across sites in the Asia-Pacific region was conducted; involving female IBD cases and asymptomatic controls. Subjects completed a questionnaire addressing questions related to OCP use. Primary outcome was the risk of development of IBD of those exposed to OCP versus non-exposure. Secondary outcomes were development of Crohn’s disease (CD) versus ulcerative colitis (UC), and whether age of first use of OCP use may be associated with risk of IBD. Results: Three hundred and forty-eight female IBD cases (41% CD, median age: 43 years) and 590 female age-matched controls were recruited. No significant association was found between OCP use and the risk of IBD (odds ratio [OR], 1.65; 95% confidence interval, 0.77–3.13; P=0.22), CD (OR, 1.55) or UC (OR, 1.01). The lack of association persisted when results were adjusted for age and smoking. IBD cases commenced OCP use at a younger age than controls (18 years vs. 20 years, P=0.049). Conclusions: In this large cohort of subjects from the Asia-Pacific region, we found a modest but not significantly increased risk of developing IBD amongst OCP users.

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