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Ahammad, A.J. Saleh,Pal, Poly Rani,Shah, Syed Shaheen,Islam, Tamanna,Mahedi Hasan, Md.,Qasem, Mohammed Ameen Ahmed,Odhikari, Noyon,Sarker, Subrata,Kim, Dong Min,Abdul Aziz, Md. Elsevier 2019 Journal of Electroanalytical Chemistry Vol.832 No.-
<P><B>Abstract</B></P> <P>Aiming at constructing a new nonenzymatic electrochemical nitrite sensor, we have prepared a screen-printed fluorine-doped tin oxide (FTO) electrode with activated jute carbon paste (AJCP) (AJCP-SP-FTO) synthesized from jute (<I>Corchorus</I> genus) sticks by using ZnCl<SUB>2</SUB> as activating agent and subsequent carbonizing at 850°C. Surface morphology, textural properties, chemical composition and nature of pores of AJC were studied by FE-SEM, XRD, EDS, Raman spectroscopy and BET analysis. The surface area of the AJC was found to be 1452.4m<SUP>2</SUP>/g with an average pore diameter of 2.6nm obtained from a BJH pore-size distribution curve. Electron transfer capacity at the interface of the AJCP material screen-printed FTO was studied by cyclic voltammetry (CV) and EIS techniques. The AJCP-SP-FTO sensor was used for amperometric detection of nitrite. The limit of detection (LOD) for nitrite oxidation was found to be 437nM for the proposed sensor. The sensitivity of AJCP-SP-FTO toward nitrite was 863.71μAmM<SUP>−1</SUP> cm<SUP>−2</SUP>. From the analysis of electrochemical data, the effective surface area of the AJCP-SP-FTO was 0.12cm<SUP>2</SUP>. We proposed a mechanism for sensitive detection of nitrite based on analysis of experimental findings of spectroscopic and electroanalytical techniques. We further utilized the proposed sensor for analyzing nitrite in tap water. The AJCP-SP-FTO electrode showed good reproducibility and stability.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Activated jute carbon (AJC) material was prepared by using ZnCl<SUB>2</SUB> as activating agent. </LI> <LI> Surface morphology, textural properties, chemical composition and nature of pores of AJC were studied. </LI> <LI> A novel AJC paste screen printed FTO electrode was constructed for nonenzymatic electrochemical determination of nitrite. </LI> <LI> The detection limit and sensitivity of nitrite were calculated to be 437 nM and 863.71 μA μM<SUP>-1</SUP> cm<SUP>-2</SUP>, respectively. </LI> <LI> A mechanism for detection of nitrite was proposed based on analysis of spectroscopic and electroanalytical techniques. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
( Yudianti Pangestu ),( Ari Fahrial Syam ),( Ahmad Fauzi ),( Murdani Abdullah ),( Dadang Makmun ),( Marcellus Simadibrata ),( Chudahman Manan ),( Aziz Rani ),( H Daldiyono ) 대한소화기학회 2007 SIDDS Vol.9 No.-
Background/Aims: Obstructive jaundice may be caused by extrahepatic cholestatic (CBD stones, pancreas and ampula cancer, CBD stricture, cholangiocarcinoma) and intra hepatic cholestatic. The aim of this study was to know what was the cause of obstructive jaundice based on ERCP evaluation. Methods: We did the retrospective study based on data of ERCP in Cipto Mangunkusumo Hospital in October 2004 until Mei 2007 Results: We evaluated 95 patients which has be done ERCP examination. We got complete data in 76 patients. Male was more frequent than female (61.8% vs 38.2%), with age range was 20-80 years old (age mean was 48.47 years old). We found CBD stones in 33 (43.4%) patients, papilla vateri tumour in 10 (13.2%) patients, head of pancreatic cancer in 8 (10.5%) patients, CBD stricture in 3 (3.9%) patients, cholangiocarcinoma in 1 (1.3%) patient, Klatskin tumour in 1 (1.3%) patient and unknown etiology obstructive in 4 (5.3%) patients. Obstructive jaundice was the most indication in ERCP examination, in 47 (61.8%) patients, followed by cholelithiasis in 22 (28.9%) patients. Sphincterotomy and stones extraction has be done in 17 (22.4%) patients, ductal cleansing in 3 (3.9%) patients, CBD stenting was performed in 17 (22.4%) pasien. We sent to surgery in 13 (17.1%) patients. ERCP failed was reported in 15 (19.7%) patients, most in the of pancreatic cancer patients. Conclusions: We found CBD stones was the most cause of obstructive jaundice, based on ERCP evaluation. ERCP has done successfully in 80.3% patients and therapeutics has done in 48.7% patients.
( Khean Lee Goh ),( Myung Gyu Choi ),( Ping I Hsu ),( Hoon Jai Chun ),( Varocha Mahachai ),( Udom Kachintorn ),( Somchai Leelakusolvong ),( Nayoung Kim ),( Abdul Aziz Rani ),( Benjamin C Y Wong ),( Ju 대한소화기기능성질환·운동학회(구 대한소화관운동학회) 2016 Journal of Neurogastroenterology and Motility (JNM Vol.22 No.3
Although gastroesophageal reflux disease is not as common in Asia as in western countries, the prevalence has increased substantially during the past decade. Gastroesophageal reflux disease is associated with considerable reductions in subjective well-being and work productivity, as well as increased healthcare use. Proton pump inhibitors (PPIs) are currently the most effective treatment for gastroesophageal reflux disease. However, there are limitations associated with these drugs in terms of partial and non-response. Dexlansoprazole is the first PPI with a dual delayed release formulation designed to provide 2 separate releases of medication to extend the duration of effective plasma drug concentration. Dexlansoprazole has been shown to be effective for healing of erosive esophagitis, and to improve subjective well-being by controlling 24-hour symptoms. Dexlansoprazole has also been shown to achieve good plasma concentration regardless of administration with food, providing flexible dosing. Studies in healthy volunteers showed no clinically important effects on exposure to the active metabolite of clopidogrel or clopidogrel-induced platelet inhibition, with no dose adjustment of clopidogrel necessary when coprescribed. This review discusses the role of the new generation PPI, dexlansoprazole, in the treatment of gastroesophageal reflux disease in Asia. (J Neurogastroenterol Motil 2016;22:355-366)